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Papers authored by Glimcher LH

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The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes.

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Jenner RG, Townsend MJ, Jackson I, Sun K, Bouwman RD, Young RA, Glimcher LH, and Lord GM

Proceedings of the National Academy of Sciences of the United States of America 106(42):17876-81, 2009 Oct 20 - Who cited this? | PubMed ID: 19805038 | Fulltext

XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy.

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Hetz C, Thielen P, Matus S, Nassif M, Court F, Kiffin R, Martinez G, Cuervo AM, Brown RH, and Glimcher LH

Genes & development 23(19):2294-306, 2009 Oct 1 - Who cited this? | PubMed ID: 19762508 | Fulltext

XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development.

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Todd DJ, McHeyzer-Williams LJ, Kowal C, Lee AH, Volpe BT, Diamond B, McHeyzer-Williams MG, and Glimcher LH

The Journal of experimental medicine 206(10):2151-9, 2009 Sep 28 - Who cited this? | PubMed ID: 19752183 | Fulltext

Fine-tuning of the unfolded protein response: Assembling the IRE1alpha interactome.

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Hetz C and Glimcher LH

Molecular cell 35(5):551-61, 2009 Sep 11 - Who cited this? | PubMed ID: 19748352 | Fulltext

Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells.

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Garrett WS, Punit S, Gallini CA, Michaud M, Zhang D, Sigrist KS, Lord GM, Glickman JN, and Glimcher LH

Cancer cell 16(3):208-19, 2009 Sep 8 - Who cited this? | PubMed ID: 19732721 | Fulltext

Intersection of the unfolded protein response and hepatic lipid metabolism.

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Lee AH and Glimcher LH

Cellular and molecular life sciences : CMLS 66(17):2835-50, 2009 Sep - Who cited this? | PubMed ID: 19468685 | Fulltext

From sugar to fat: How the transcription factor XBP1 regulates hepatic lipogenesis.

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Glimcher LH and Lee AH

Annals of the New York Academy of Sciences 1173 Suppl 1:E2-9, 2009 Sep - Who cited this? | PubMed ID: 19751410 | Fulltext

TAK1 is an essential regulator of BMP signalling in cartilage.

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Shim JH, Greenblatt MB, Xie M, Schneider MD, Zou W, Zhai B, Gygi S, and Glimcher LH

The EMBO journal 28(14):2028-41, 2009 Jul 22 - Who cited this? | PubMed ID: 19536134 | Fulltext

T-bet-deficient NOD mice are protected from diabetes due to defects in both T Cell and innate immune system function.

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Esensten JH, Lee MR, Glimcher LH, and Bluestone JA

Journal of immunology (Baltimore, Md. : 1950) 183(1):75-82, 2009 Jul 1 - Who cited this? | PubMed ID: 19535634 | Fulltext

Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells.

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Yuan X, Ansari MJ, D'Addio F, Paez-Cortez J, Schmitt I, Donnarumma M, Boenisch O, Zhao X, Popoola J, Clarkson MR, Yagita H, Akiba H, Freeman GJ, Iacomini J, Turka LA, Glimcher LH,

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Proceedings of the National Academy of Sciences of the United States of America 106(26):10734-9, 2009 Jun 30 - Who cited this? | PubMed ID: 19528638 | Fulltext

Harvard's women four years later.

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Glimcher LH and Lieberman J

Nature immunology 10(6):559-61, 2009 Jun - Who cited this? | PubMed ID: 19448653 | Fulltext

Control of T helper cell differentiation through cytokine receptor inclusion in the immunological synapse.

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Maldonado RA, Soriano MA, Perdomo LC, Sigrist K, Irvine DJ, Decker T, and Glimcher LH

The Journal of experimental medicine 206(4):877-92, 2009 Apr 13 - Who cited this? | PubMed ID: 19349465 | Fulltext

BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha.

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Lisbona F, Rojas-Rivera D, Thielen P, Zamorano S, Todd D, Martinon F, Glavic A, Kress C, Lin JH, Walter P, Reed JC, Glimcher LH, and Hetz C

Molecular cell 33(6):679-91, 2009 Mar 27 - Who cited this? | PubMed ID: 19328063 | Fulltext

The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells.

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Lazarevic V, Zullo AJ, Schweitzer MN, Staton TL, Gallo EM, Crabtree GR, and Glimcher LH

Nature immunology 10(3):306-13, 2009 Mar - Who cited this? | PubMed ID: 19169262 | Fulltext

Restoration of T-box-containing protein expressed in T cells protects against allergen-induced asthma.

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Park JW, Min HJ, Sohn JH, Kim JY, Hong JH, Sigrist KS, Glimcher LH, and Hwang ES

The Journal of allergy and clinical immunology 123(2):479-85, 2009 Feb - Who cited this? | PubMed ID: 19081613 | Fulltext

T-bet-/- RAG2-/- ulcerative colitis: the role of T-bet as a peacekeeper of host-commensal relationships.

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Garrett WS and Glimcher LH

Cytokine 48(1-2):144-7, 2009 - Who cited this? | PubMed ID: 19666230 | Fulltext

A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathy.

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Yuan X, Paez-Cortez J, Schmitt-Knosalla I, D'Addio F, Mfarrej B, Donnarumma M, Habicht A, Clarkson MR, Iacomini J, Glimcher LH, Sayegh MH, and Ansari MJ

The Journal of experimental medicine 205(13):3133-44, 2008 Dec 22 - Who cited this? | PubMed ID: 19047438 | Fulltext

HCO3-/Cl- anion exchanger SLC4A2 is required for proper osteoclast differentiation and function.

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Wu J, Glimcher LH, and Aliprantis AO

Proceedings of the National Academy of Sciences of the United States of America 105(44):16934-9, 2008 Nov 4 - Who cited this? | PubMed ID: 18971331 | Fulltext

NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism.

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Aliprantis AO, Ueki Y, Sulyanto R, Park A, Sigrist KS, Sharma SM, Ostrowski MC, Olsen BR, and Glimcher LH

The Journal of clinical investigation, 2008 Oct 9 - Who cited this? | PubMed ID: 18846253 | Fulltext

XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease.

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Kaser A, Lee AH, Franke A, Glickman JN, Zeissig S, Tilg H, Nieuwenhuis EE, Higgins DE, Schreiber S, Glimcher LH, and Blumberg RS

Cell 134(5):743, 2008 Sep 5 - Who cited this? | PubMed ID: 18775308 | Fulltext

The endoplasmic reticulum stress response in immunity and autoimmunity.

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Todd DJ, Lee AH, and Glimcher LH

Nature reviews. Immunology, 2008 Aug 1 - Who cited this? | PubMed ID: 18670423 | Fulltext

T-bet plays a key role in NK-mediated control of melanoma metastatic disease.

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Werneck MB, Lugo-Villarino G, Hwang ES, Cantor H, and Glimcher LH

Journal of immunology (Baltimore, Md. : 1950) 180(12):8004-10, 2008 Jun 15 - Who cited this? | PubMed ID: 18523263 | Fulltext

Regulation of hepatic lipogenesis by the transcription factor XBP1.

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Lee AH, Scapa EF, Cohen DE, and Glimcher LH

Science (New York, N.Y.) 320(5882):1492, 2008 Jun 13 - Who cited this? | PubMed ID: 18556558 | Fulltext

Functional Th1 cells are required for surgical adhesion formation in a murine model.

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Tzianabos AO, Holsti MA, Zheng XX, Stucchi AF, Kuchroo VK, Strom TB, Glimcher LH, and Cruikshank WW

Journal of immunology (Baltimore, Md. : 1950) 180(10):6970, 2008 May 15 - Who cited this? | PubMed ID: 18453619 | Fulltext

Protective role of nuclear factor of activated T cells 2 in CD8+ long-lived memory T cells in an allergy model.

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Karwot R, Maxeiner JH, Schmitt S, Scholtes P, Hausding M, Lehr HA, Glimcher LH, and Finotto S

The Journal of allergy and clinical immunology 121(4):992, 2008 Apr - Who cited this? | PubMed ID: 18329088 | Fulltext

Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice.

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Mukherjee S, Raje N, Schoonmaker JA, Liu JC, Hideshima T, Wein MN, Jones DC, Vallet S, Bouxsein ML, Pozzi S, Chhetri S, Seo YD, Aronson JP, Patel C, Fulciniti M, Purton LE,

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The Journal of clinical investigation 118(2):491, 2008 Feb - Who cited this? | PubMed ID: 18219387 | Fulltext

NFATc1 Balances Quiescence and Proliferation of Skin Stem Cells.

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Horsley V, Aliprantis AO, Polak L, Glimcher LH, and Fuchs E

Cell 132(2):299-310, 2008 Jan 25 - Who cited this? | PubMed ID: 18243104 | Fulltext

Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis.

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Hetz C, Lee AH, Gonzalez-Romero D, Thielen P, Castilla J, Soto C, and Glimcher LH

Proceedings of the National Academy of Sciences of the United States of America 105(2):757, 2008 Jan 15 - Who cited this? | PubMed ID: 18178615 | Fulltext

Mycobacterium tuberculosis Rv2224c modulates innate immune responses.

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Rengarajan J, Murphy E, Park A, Krone CL, Hett EC, Bloom BR, Glimcher LH, and Rubin EJ

Proceedings of the National Academy of Sciences of the United States of America 105(1):264-9, 2008 Jan 8 - Who cited this? | PubMed ID: 18172199 | Fulltext

Lentivirus Delivery of shRNA Constructs into Osteoblasts.

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Wein MN, Jones DC, and Glimcher LH

Methods in molecular biology (Clifton, N.J.) 455:149-55, 2008 - Who cited this? | PubMed ID: 18463817 | Fulltext

Control of postnatal bone mass by the zinc finger adapter protein schnurri-3.

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Glimcher LH, Jones DC, and Wein MN

Annals of the New York Academy of Sciences 1116:174-81, 2007 Dec - Who cited this? | PubMed ID: 18083927 | Fulltext

Schnurri-3 is an essential regulator of osteoblast function and adult bone mass.

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Jones DC, Wein MN, and Glimcher LH

Annals of the rheumatic diseases 66 Suppl 3:iii49-51, 2007 Nov - Who cited this? | PubMed ID: 17934096 | Fulltext

Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system.

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Garrett WS, Lord GM, Punit S, Lugo-Villarino G, Mazmanian SK, Ito S, Glickman JN, and Glimcher LH

Cell 131(1):33-45, 2007 Oct 5 - Who cited this? | PubMed ID: 17923086 | Fulltext

The transcription factor XBP-1 is essential for the development and survival of dendritic cells.

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Iwakoshi NN, Pypaert M, and Glimcher LH

The Journal of experimental medicine 204(10):2267, 2007 Oct 1 - Who cited this? | PubMed ID: 17875675 | Fulltext

Constraints in antigen presentation severely restrict T cell recognition of the allogeneic fetus.

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Erlebacher A, Vencato D, Price KA, Zhang D, and Glimcher LH

The Journal of clinical investigation 117(5):1399, 2007 May - Who cited this? | PubMed ID: 17446933 | Fulltext

Trawling for treasure: tales of T-bet.

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Glimcher LH

Nature immunology 8(5):448-50, 2007 May - Who cited this? | PubMed ID: 17440449 | Fulltext

Transcription factor T-bet regulates skin sclerosis through its function in innate immunity and via IL-13.

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Aliprantis AO, Wang J, Fathman JW, Lemaire R, Dorfman DM, Lafyatis R, and Glimcher LH

Proceedings of the National Academy of Sciences of the United States of America 104(8):2827, 2007 Feb 20 - Who cited this? | PubMed ID: 17307869 | Fulltext

Dendritic cell expression of the transcription factor T-bet regulates mast cell progenitor homing to mucosal tissue.

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Alcaide P, Jones TG, Lord GM, Glimcher LH, Hallgren J, Arinobu Y, Akashi K, Paterson AM, Gurish MA, and Luscinskas FW

The Journal of experimental medicine 204(2):431-9, 2007 Feb 19 - Who cited this? | PubMed ID: 17296784 | Fulltext

Schnurri-3: a key regulator of postnatal skeletal remodeling.

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Jones DC, Wein MN, and Glimcher LH

Advances in experimental medicine and biology 602:1-13, 2007 - Who cited this? | PubMed ID: 17966382 | Fulltext

T-bet controls pathogenicity of CTLs in the heart by separable effects on migration and effector activity.

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Taqueti VR, Grabie N, Colvin R, Pang H, Jarolim P, Luster AD, Glimcher LH, and Lichtman AH

Journal of immunology (Baltimore, Md. : 1950) 177(9):5890-901, 2006 Nov 1 - Who cited this? | PubMed ID: 17056513 | Fulltext

Gout: new insights into an old disease.

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Martinon F and Glimcher LH

The Journal of clinical investigation 116(8):2073-5, 2006 Aug - Who cited this? | PubMed ID: 16886051 | Fulltext

Cutting edge: STAT1 and T-bet play distinct roles in determining outcome of visceral leishmaniasis caused by Leishmania donovani.

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Rosas LE, Snider HM, Barbi J, Satoskar AA, Lugo-Villarino G, Keiser T, Papenfuss T, Durbin JE, Radzioch D, Glimcher LH, and Satoskar AR

Journal of immunology (Baltimore, Md. : 1950) 177(1):22-5, 2006 Jul 1 - Who cited this? | PubMed ID: 16785492 | Fulltext

Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3.

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Jones DC, Wein MN, Oukka M, Hofstaetter JG, Glimcher MJ, and Glimcher LH

Science (New York, N.Y.) 312(5777):1223-7, 2006 May 26 - Who cited this? | PubMed ID: 16728642 | Fulltext

Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells.

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Shinohara ML, Lu L, Bu J, Werneck MB, Kobayashi KS, Glimcher LH, and Cantor H

Nature immunology 7(5):498-506, 2006 May - Who cited this? | PubMed ID: 16604075 | Fulltext

Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha.

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Hetz C, Bernasconi P, Fisher J, Lee AH, Bassik MC, Antonsson B, Brandt GS, Iwakoshi NN, Schinzel A, Glimcher LH, and Korsmeyer SJ

Science (New York, N.Y.) 312(5773):572-6, 2006 Apr 28 - Who cited this? | PubMed ID: 16645094 | Fulltext

Rapid turnover of unspliced Xbp-1 as a factor that modulates the unfolded protein response.

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Tirosh B, Iwakoshi NN, Glimcher LH, and Ploegh HL

The Journal of biological chemistry 281(9):5852-60, 2006 Mar 3 - Who cited this? | PubMed ID: 16332684 | Fulltext

Transcription factor T-bet regulates inflammatory arthritis through its function in dendritic cells.

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Wang J, Fathman JW, Lugo-Villarino G, Scimone L, von Andrian U, Dorfman DM, and Glimcher LH

The Journal of clinical investigation 116(2):414-21, 2006 Feb - Who cited this? | PubMed ID: 16410834 | Fulltext

T-bet polymorphisms are associated with asthma and airway hyperresponsiveness.

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Raby BA, Hwang ES, Van Steen K, Tantisira K, Peng S, Litonjua A, Lazarus R, Giallourakis C, Rioux JD, Sparrow D, Silverman EK, Glimcher LH, and Weiss ST

American journal of respiratory and critical care medicine 173(1):64-70, 2006 Jan 1 - Who cited this? | PubMed ID: 16179640 | Fulltext

XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands.

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Lee AH, Chu GC, Iwakoshi NN, and Glimcher LH

The EMBO journal 24(24):4368-80, 2005 Dec 21 - Who cited this? | PubMed ID: 16362047 | Fulltext

Turning down the system: counter-regulatory mechanisms in bone and adaptive immunity.

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Wein MN, Jones DC, and Glimcher LH

Immunological reviews 208:66-79, 2005 Dec - Who cited this? | PubMed ID: 16313341 | Fulltext

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