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Papers authored by Glaeser RM

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Survey of large protein complexes in D. vulgaris reveals great structural diversity.

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Han BG, Dong M, Liu H, Camp L, Geller J, Singer M, Hazen TC, Choi M, Witkowska HE, Ball DA, Typke D, Downing KH, Shatsky M, Brenner SE, Chandonia JM, Biggin MD,

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Proceedings of the National Academy of Sciences of the United States of America 106(39):16580-5, 2009 Sep 29 - Who cited this? | PubMed ID: 19805340 | Fulltext

A method for the alignment of heterogeneous macromolecules from electron microscopy.

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Shatsky M, Hall RJ, Brenner SE, and Glaeser RM

Journal of structural biology 166(1):67-78, 2009 Apr - Who cited this? | PubMed ID: 19166941 | Fulltext

Practical factors affecting the performance of a thin-film phase plate for transmission electron microscopy.

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Danev R, Glaeser RM, and Nagayama K

Ultramicroscopy 109(4):312-25, 2009 Mar - Who cited this? | PubMed ID: 19157711 | Fulltext

Retrospective: Radiation damage and its associated "Information Limitations".

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Glaeser RM

Journal of structural biology 163(3):271-6, 2008 Sep - Who cited this? | PubMed ID: 18588985 | Fulltext

Retrospective on the early development of cryoelectron microscopy of macromolecules and a prospective on opportunities for the future.

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Taylor KA and Glaeser RM

Journal of structural biology 163(3):214-23, 2008 Sep - Who cited this? | PubMed ID: 18606231 | Fulltext

Restoration of weak phase-contrast images recorded with a high degree of defocus: The "twin image" problem associated with CTF correction.

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Downing KH and Glaeser RM

Ultramicroscopy 108(9):921-8, 2008 Aug - Who cited this? | PubMed ID: 18508199 | Fulltext

Macromolecular structures without crystals.

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Glaeser RM

Proceedings of the National Academy of Sciences of the United States of America 105(6):1779-80, 2008 Feb 12 - Who cited this? | PubMed ID: 18256181 | Fulltext

Octomeric pyruvate-ferredoxin oxidoreductase from Desulfovibrio vulgaris.

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Garczarek F, Dong M, Typke D, Witkowska HE, Hazen TC, Nogales E, Biggin MD, and Glaeser RM

Journal of structural biology 159(1):9-18, 2007 Jul - Who cited this? | PubMed ID: 17400475 | Fulltext

The parallelization of SPIDER on distributed-memory computers using MPI.

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Yang C, Penczek PA, Leith A, Asturias FJ, Ng EG, Glaeser RM, and Frank J

Journal of structural biology 157(1):240-9, 2007 Jan - Who cited this? | PubMed ID: 16859923 | Fulltext

SPARX, a new environment for Cryo-EM image processing.

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Hohn M, Tang G, Goodyear G, Baldwin PR, Huang Z, Penczek PA, Yang C, Glaeser RM, Adams PD, and Ludtke SJ

Journal of structural biology 157(1):47-55, 2007 Jan - Who cited this? | PubMed ID: 16931051 | Fulltext

Stroboscopic image capture: reducing the dose per frame by a factor of 30 does not prevent beam-induced specimen movement in paraffin.

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Typke D, Gilpin CJ, Downing KH, and Glaeser RM

Ultramicroscopy 107(2-3):106-15, 2007 - Who cited this? | PubMed ID: 16905258 | Fulltext

Design of a microfabricated, two-electrode phase-contrast element suitable for electron microscopy.

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Cambie R, Downing KH, Typke D, Glaeser RM, and Jin J

Ultramicroscopy 107(4-5):329-39, 2007 - Who cited this? | PubMed ID: 17079082 | Fulltext

Membrane-protein stability in a phospholipid-based crystallization medium.

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Lunde CS, Rouhani S, Facciotti MT, and Glaeser RM

Journal of structural biology 154(3):223-31, 2006 Jun - Who cited this? | PubMed ID: 16600634 | Fulltext

Molecular architecture and assembly mechanism of Drosophila tripeptidyl peptidase II.

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Rockel B, Peters J, Müller SA, Seyit G, Ringler P, Hegerl R, Glaeser RM, and Baumeister W

Proceedings of the National Academy of Sciences of the United States of America 102(29):10135-40, 2005 Jul 19 - Who cited this? | PubMed ID: 16006508 | Fulltext

High-throughput film-densitometry: an efficient approach to generate large data sets.

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Typke D, Nordmeyer RA, Jones A, Lee J, Avila-Sakar A, Downing KH, and Glaeser RM

Journal of structural biology 149(1):17-29, 2005 Jan - Who cited this? | PubMed ID: 15629654 | Fulltext

Experimental characterization and mitigation of specimen charging on thin films with one conducting layer.

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Downing KH, McCartney MR, and Glaeser RM

Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 10(6):783-9, 2004 Dec - Who cited this? | PubMed ID: 19780320 | Fulltext

Specimen charging on thin films with one conducting layer: discussion of physical principles.

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Glaeser RM and Downing KH

Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 10(6):790-6, 2004 Dec - Who cited this? | PubMed ID: 19780321 | Fulltext

Energy transduction in transmembrane ion pumps.

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Facciotti MT, Rouhani-Manshadi S, and Glaeser RM

Trends in biochemical sciences 29(8):445-51, 2004 Aug - Who cited this? | PubMed ID: 15362229 | Fulltext

Specificity of anion binding in the substrate pocket of bacteriorhodopsin.

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Facciotti MT, Cheung VS, Lunde CS, Rouhani S, Baliga NS, and Glaeser RM

Biochemistry 43(17):4934-43, 2004 May 4 - Who cited this? | PubMed ID: 15109251 | Fulltext

Crystal structures of bR(D85S) favor a model of bacteriorhodopsin as a hydroxyl-ion pump.

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Facciotti MT, Rouhani S, and Glaeser RM

FEBS letters 564(3):301-6, 2004 Apr 30 - Who cited this? | PubMed ID: 15111113 | Fulltext

Automatic particle selection: results of a comparative study.

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Zhu Y, Carragher B, Glaeser RM, Fellmann D, Bajaj C, Bern M, Mouche F, de Haas F, Hall RJ, Kriegman DJ, Ludtke SJ, Mallick SP, Penczek PA, Roseman AM, Sigworth FJ, Volkmann N,

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Journal of structural biology 145(1-2):3-14 - Who cited this? | PubMed ID: 15065668 | Fulltext

Electron microscopy of biological macromolecules: bridging the gap between what physics allows and what we currently can get.

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Typke D, Downing KH, and Glaeser RM

Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 10(1):21-7, 2004 Feb - Who cited this? | PubMed ID: 15306063 | Fulltext

Historical background: Why is it important to improve automated particle selection methods?.

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Glaeser RM

Journal of structural biology 145(1-2):15-8, 2004 - Who cited this? | PubMed ID: 15065669 | Fulltext

A binary segmentation approach for boxing ribosome particles in cryo EM micrographs.

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Adiga PS, Malladi R, Baxter W, and Glaeser RM

Journal of structural biology 145(1-2):142-51, 2004 - Who cited this? | PubMed ID: 15065681 | Fulltext

Crystal structure of the bromide-bound D85S mutant of bacteriorhodopsin: principles of ion pumping.

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Facciotti MT, Cheung VS, Nguyen D, Rouhani S, and Glaeser RM

Biophysical journal 85(1):451-8, 2003 Jul - Who cited this? | PubMed ID: 12829500 | Fulltext

Three-dimensional diffractive imaging for crystalline monolayers with one-dimensional compact support.

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Spence JC, Weierstall U, Fricke TT, Glaeser RM, and Downing KH

Journal of structural biology 144(1-2):209-18, 2003 - Who cited this? | PubMed ID: 14643223 | Fulltext

A giant protease with a twist: the TPP II complex from Drosophila studied by electron microscopy.

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Rockel B, Peters J, Kühlmorgen B, Glaeser RM, and Baumeister W

The EMBO journal 21(22):5979-84, 2002 Nov 15 - Who cited this? | PubMed ID: 12426370 | Fulltext

Modeling chemical bonding effects for protein electron crystallography: the transferable fragmental electrostatic potential (TFESP) method.

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Zhong S, Dadarlat VM, Glaeser RM, Head-Gordon T, and Downing KH

Acta crystallographica. Section A, Foundations of crystallography 58(Pt 2):162-70, 2002 Mar - Who cited this? | PubMed ID: 11832586 | Fulltext

Crystallization of membrane proteins from media composed of connected-bilayer gels.

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Rouhani S, Facciotti MT, Woodcock G, Cheung V, Cunningham C, Nguyen D, Rad B, Lin CT, Lunde CS, and Glaeser RM

Biopolymers 66(5):300-16, 2002 - Who cited this? | PubMed ID: 12539259 | Fulltext

Structure of an early intermediate in the M-state phase of the bacteriorhodopsin photocycle.

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Facciotti MT, Rouhani S, Burkard FT, Betancourt FM, Downing KH, Rose RB, McDermott G, and Glaeser RM

Biophysical journal 81(6):3442-55, 2001 Dec - Who cited this? | PubMed ID: 11721006 | Fulltext

Crystal structure of the D85S mutant of bacteriorhodopsin: model of an O-like photocycle intermediate.

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Rouhani S, Cartailler JP, Facciotti MT, Walian P, Needleman R, Lanyi JK, Glaeser RM, and Luecke H

Journal of molecular biology 313(3):615-28, 2001 Oct 26 - Who cited this? | PubMed ID: 11676543 | Fulltext

Review: automatic particle detection in electron microscopy.

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Nicholson WV and Glaeser RM

Journal of structural biology 133(2-3):90-101, 2001 - Who cited this? | PubMed ID: 11472081 | Fulltext

Chemical and physical evidence for multiple functional steps comprising the M state of the bacteriorhodopsin photocycle.

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Betancourt FM and Glaeser RM

Biochimica et biophysica acta 1460(1):106-18, 2000 Aug 30 - Who cited this? | PubMed ID: 10984594 | Fulltext

Review: electron crystallography: present excitement, a nod to the past, anticipating the future.

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Glaeser RM

Journal of structural biology 128(1):3-14, 1999 Dec 1 - Who cited this? | PubMed ID: 10600552 | Fulltext

Chemical bonding effects in the determination of protein structures by electron crystallography.

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Chang S, Head-Gordon T, Glaeser RM, and Downing KH

Acta crystallographica. Section A, Foundations of crystallography 55 ( Pt 2 Pt 2):305-13, 1999 Mar 1 - Who cited this? | PubMed ID: 10927261 | Fulltext

Structural characterization of the L-to-M transition of the bacteriorhodopsin photocycle.

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Hendrickson FM, Burkard F, and Glaeser RM

Biophysical journal 75(3):1446-54, 1998 Sep - Who cited this? | PubMed ID: 9726946 | Fulltext

Differences in hydration structure near hydrophobic and hydrophilic amino acids.

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Head-Gordon T, Sorenson JM, Pertsemlidis A, and Glaeser RM

Biophysical journal 73(4):2106-15, 1997 Oct - Who cited this? | PubMed ID: 9336206 | Fulltext

Direct evidence for modified solvent structure within the hydration shell of a hydrophobic amino acid.

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Pertsemlidis A, Saxena AM, Soper AK, Head-Gordon T, and Glaeser RM

Proceedings of the National Academy of Sciences of the United States of America 93(20):10769-74, 1996 Oct 1 - Who cited this? | PubMed ID: 8855255 | Fulltext

The relevance of dose-fractionation in tomography of radiation-sensitive specimens.

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McEwen BF, Downing KH, and Glaeser RM

Ultramicroscopy 60(3):357-73, 1995 Oct - Who cited this? | PubMed ID: 8525549 | Fulltext

Crystallographic extraction and averaging of data from small image areas.

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Perkins GA, Downing KH, and Glaeser RM

Ultramicroscopy 60(2):283-94, 1995 Sep - Who cited this? | PubMed ID: 7502383 | Fulltext

Two progressive substrates of the M-intermediate can be identified in glucose-embedded, wild-type bacteriorhodopsin.

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Vonck J, Han BG, Burkard F, Perkins GA, and Glaeser RM

Biophysical journal 67(3):1173-8, 1994 Sep - Who cited this? | PubMed ID: 7811930 | Fulltext

The bacteriorhodopsin photocycle: direct structural study of two substrates of the M-intermediate.

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Han BG, Vonck J, and Glaeser RM

Biophysical journal 67(3):1179-86, 1994 Sep - Who cited this? | PubMed ID: 7811931 | Fulltext

Specimen flatness of glucose-embedded biological materials for electron crystallography is affected significantly by the choice of carbon evaporation stock.

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Han BG, Wolf SG, Vonck J, and Glaeser RM

Ultramicroscopy 55(1):1-5, 1994 Jul - Who cited this? | PubMed ID: 7974847 | Fulltext

Probing toward atomic resolution in molecular topography.

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Glaeser RM

Proceedings of the National Academy of Sciences of the United States of America 91(6):1981-2, 1994 Mar 15 - Who cited this? | PubMed ID: 11607464 | Fulltext

Overview of significant challenges in molecular biology amenable to computational methods.

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Glaeser RM

Basic life sciences 63:11-8; discussion 18-9, 1994 - Who cited this? | PubMed ID: 7755540 | Fulltext

High-resolution electron crystallography of protein molecules.

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Glaeser RM and Downing KH

Ultramicroscopy 52(3-4):478-86, 1993 Dec - Who cited this? | PubMed ID: 8116103 | Fulltext

Glucose alone does not completely hydrate bacteriorhodopsin in glucose-embedded purple membrane.

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Perkins GA, Burkard F, Liu E, and Glaeser RM

Journal of microscopy 169(Pt 1):61-5, 1993 Jan - Who cited this? | PubMed ID: 8445632 | Fulltext

Assessment of resolution in biological electron crystallography.

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Glaeser RM and Downing KH

Ultramicroscopy 47(1-3):256-65, 1992 Nov - Who cited this? | PubMed ID: 1481279 | Fulltext

Specimen flatness of thin crystalline arrays: influence of the substrate.

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Glaeser RM

Ultramicroscopy 46(1-4):33-43, 1992 Oct - Who cited this? | PubMed ID: 1481276 | Fulltext

Characterization of the conformational change in the M1 and M2 substates of bacteriorhodopsin by the combined use of visible and infrared spectroscopy.

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Perkins GA, Liu E, Burkard F, Berry EA, and Glaeser RM

Journal of structural biology 109(2):142-51, 1992 - Who cited this? | PubMed ID: 1288615 | Fulltext

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