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Papers authored by Gessler M

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WTX inactivation is a frequent, but late event in Wilms tumors without apparent clinical impact.

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Wegert J, Wittmann S, Leuschner I, Geissinger E, Graf N, and Gessler M

Genes, chromosomes & cancer 48(12):1102-11, 2009 Dec - Who cited this? | PubMed ID: 19760609 | Fulltext

Novel features of boundary cap cells revealed by the analysis of newly identified molecular markers.

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Coulpier F, Le Crom S, Maro GS, Manent J, Giovannini M, Maciorowski Z, Fischer A, Gessler M, Charnay P, and Topilko P

Glia 57(13):1450-7, 2009 Oct - Who cited this? | PubMed ID: 19243017 | Fulltext

Loss of heterozygosity at 2q37 in sporadic Wilms' tumor: putative role for miR-562.

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Drake KM, Ruteshouser EC, Natrajan R, Harbor P, Wegert J, Gessler M, Pritchard-Jones K, Grundy P, Dome J, Huff V, Jones C, and Aldred MA

Clinical cancer research : an official journal of the American Association for Cancer Research 15(19):5985-92, 2009 Oct 1 - Who cited this? | PubMed ID: 19789318 | Fulltext

Dll1 and Dll4: similar, but not the same.

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Gessler M

Blood 113(22):5375-6, 2009 May 28 - Who cited this? | PubMed ID: 19478053 | Fulltext

Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti.

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Doetzlhofer A, Basch ML, Ohyama T, Gessler M, Groves AK, and Segil N

Developmental cell 16(1):58-69, 2009 Jan - Who cited this? | PubMed ID: 19154718 | Fulltext

Integrated Regulation of Toll-like Receptor Responses by Notch and Interferon-gamma Pathways.

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Hu X, Chung AY, Wu I, Foldi J, Chen J, Ji JD, Tateya T, Kang YJ, Han J, Gessler M, Kageyama R, and Ivashkiv LB

Immunity 29(5):691-703, 2008 Nov - Who cited this? | PubMed ID: 18976936 | Fulltext

Identification of the human homolog of the imprinted mouse Air non-coding RNA.

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Yotova IY, Vlatkovic IM, Pauler FM, Warczok KE, Ambros PF, Oshimura M, Theussl HC, Gessler M, Wagner EF, and Barlow DP

Genomics, 2008 Sep 9 - Who cited this? | PubMed ID: 18789384 | Fulltext

Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease.

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Saburi S, Hester I, Fischer E, Pontoglio M, Eremina V, Gessler M, Quaggin SE, Harrison R, Mount R, and McNeill H

Nature genetics 40(8):1010, 2008 Aug - Who cited this? | PubMed ID: 18604206 | Fulltext

New prognostic markers revealed by evaluation of genes correlated with clinical parameters in Wilms tumors.

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Wittmann S, Wunder C, Zirn B, Furtwängler R, Wegert J, Graf N, and Gessler M

Genes, chromosomes & cancer 47(5):386, 2008 May - Who cited this? | PubMed ID: 18260125 | Fulltext

The rodent Four-jointed ortholog Fjx1 regulates dendrite extension.

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Probst B, Rock R, Gessler M, Vortkamp A, and Püschel AW

Developmental biology 312(1):461-70, 2007 Dec 1 - Who cited this? | PubMed ID: 18028897 | Fulltext

Upregulation of soluble vascular endothelial growth factor receptor 1 contributes to angiogenesis defects in the placenta of alpha 2B-adrenoceptor deficient mice.

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Muthig V, Gilsbach R, Haubold M, Philipp M, Ivacevic T, Gessler M, and Hein L

Circulation research 101(7):682-91, 2007 Sep 28 - Who cited this? | PubMed ID: 17673674 | Fulltext

Combined loss of Hey1 and HeyL causes congenital heart defects because of impaired epithelial to mesenchymal transition.

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Fischer A, Steidl C, Wagner TU, Lang E, Jakob PM, Friedl P, Knobeloch KP, and Gessler M

Circulation research 100(6):856-63, 2007 Mar 30 - Who cited this? | PubMed ID: 17303760 | Fulltext

Loss of 11q and 16q in Wilms tumors is associated with anaplasia, tumor recurrence, and poor prognosis.

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Wittmann S, Zirn B, Alkassar M, Ambros P, Graf N, and Gessler M

Genes, chromosomes & cancer 46(2):163-70, 2007 Feb - Who cited this? | PubMed ID: 17099873 | Fulltext

Delta-Notch--and then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factors.

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Fischer A and Gessler M

Nucleic acids research 35(14):4583, 2007 - Who cited this? | PubMed ID: 17586813 | Fulltext

Hypoxia-mediated activation of Dll4-Notch-Hey2 signaling in endothelial progenitor cells and adoption of arterial cell fate.

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Diez H, Fischer A, Winkler A, Hu CJ, Hatzopoulos AK, Breier G, and Gessler M

Experimental cell research 313(1):1-9, 2007 Jan 1 - Who cited this? | PubMed ID: 17045587 | Fulltext

Developmental patterning of the cardiac atrioventricular canal by Notch and Hairy-related transcription factors.

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Rutenberg JB, Fischer A, Jia H, Gessler M, Zhong TP, and Mercola M

Development (Cambridge, England) 133(21):4381-90, 2006 Nov - Who cited this? | PubMed ID: 17021042 | Fulltext

Identification of limited regions of genetic aberrations in patients affected with Wilms' tumor using a tiling-path chromosome 22 array.

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Benetkiewicz M, de Ståhl TD, Gördör A, Pfeifer S, Wittmann S, Gessler M, and Dumanski JP

International journal of cancer. Journal international du cancer 119(3):571-8, 2006 Aug 1 - Who cited this? | PubMed ID: 16496407 | Fulltext

Target genes of the WNT/beta-catenin pathway in Wilms tumors.

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Zirn B, Samans B, Wittmann S, Pietsch T, Leuschner I, Graf N, and Gessler M

Genes, chromosomes & cancer 45(6):565-74, 2006 Jun - Who cited this? | PubMed ID: 16575872 | Fulltext

Expression profiling of Wilms tumors reveals new candidate genes for different clinical parameters.

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Zirn B, Hartmann O, Samans B, Krause M, Wittmann S, Mertens F, Graf N, Eilers M, and Gessler M

International journal of cancer. Journal international du cancer 118(8):1954-62, 2006 Apr 15 - Who cited this? | PubMed ID: 16287080 | Fulltext

[Structure, use, and risks of biomaterial repositories of embryonal tumors].

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Ernestus K, Pietsch T, Gessler M, Simon T, Hero B, and Berthold F

Klinische Padiatrie 218(3):132-8, 2006 - Who cited this? | PubMed ID: 16688668 | Fulltext

Very-KIND is a novel nervous system specific guanine nucleotide exchange factor for Ras GTPases.

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Mees A, Rock R, Ciccarelli FD, Leberfinger CB, Borawski JM, Bork P, Wiese S, Gessler M, and Kerkhoff E

Gene expression patterns : GEP 6(1):79-85, 2005 Dec - Who cited this? | PubMed ID: 16099729 | Fulltext

Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.

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Rock R, Schrauth S, and Gessler M

Developmental dynamics : an official publication of the American Association of Anatomists 234(3):747-55, 2005 Nov - Who cited this? | PubMed ID: 16059920 | Fulltext

Fjx1: a notch-inducible secreted ligand with specific binding sites in developing mouse embryos and adult brain.

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Rock R, Heinrich AC, Schumacher N, and Gessler M

Developmental dynamics : an official publication of the American Association of Anatomists 234(3):602-12, 2005 Nov - Who cited this? | PubMed ID: 16145673 | Fulltext

Hey basic helix-loop-helix transcription factors are repressors of GATA4 and GATA6 and restrict expression of the GATA target gene ANF in fetal hearts.

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Fischer A, Klattig J, Kneitz B, Diez H, Maier M, Holtmann B, Englert C, and Gessler M

Molecular and cellular biology 25(20):8960-70, 2005 Oct - Who cited this? | PubMed ID: 16199874 | Fulltext

All-trans retinoic acid treatment of Wilms tumor cells reverses expression of genes associated with high risk and relapse in vivo.

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Zirn B, Samans B, Spangenberg C, Graf N, Eilers M, and Gessler M

Oncogene 24(33):5246, 2005 Aug 4 - Who cited this? | PubMed ID: 15897880 | Fulltext

Novel familial WT1 read-through mutation associated with Wilms tumor and slow progressive nephropathy.

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Zirn B, Wittmann S, and Gessler M

American journal of kidney diseases : the official journal of the National Kidney Foundation 45(6):1100-4, 2005 Jun - Who cited this? | PubMed ID: 15957141 | Fulltext

Chibby, a novel antagonist of the Wnt pathway, is not involved in Wilms tumor development.

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Zirn B, Wittmann S, Graf N, and Gessler M

Cancer letters 220(1):115-20, 2005 Mar 18 - Who cited this? | PubMed ID: 15737694 | Fulltext

Transposable elements as a source of genetic innovation: expression and evolution of a family of retrotransposon-derived neogenes in mammals.

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Brandt J, Schrauth S, Veith AM, Froschauer A, Haneke T, Schultheis C, Gessler M, Leimeister C, and Volff JN

Gene 345(1):101-11, 2005 Jan 17 - Who cited this? | PubMed ID: 15716091 | Fulltext

[Botulinum toxin A in orthopedic pain therapy].

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Placzek R, Söhling M, Gessler M, and Jerosch J

Schmerz (Berlin, Germany) 18(6):498-505, 2004 Dec - Who cited this? | PubMed ID: 15586299 | Fulltext

her7 and hey1, but not lunatic fringe show dynamic expression during somitogenesis in medaka (Oryzias latipes).

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Elmasri H, Liedtke D, Lücking G, Volff JN, Gessler M, and Winkler C

Gene expression patterns : GEP 4(5):553, 2004 Sep - Who cited this? | PubMed ID: 15261833 | Fulltext

Phenotypic variability in Hey2 -/- mice and absence of HEY2 mutations in patients with congenital heart defects or Alagille syndrome.

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Fischer A, Klamt B, Schumacher N, Glaeser C, Hansmann I, Fenge H, and Gessler M

Mammalian genome : official journal of the International Mammalian Genome Society 15(9):711-6, 2004 Sep - Who cited this? | PubMed ID: 15389319 | Fulltext

Cloning and expression analysis of the mouse stroma marker Snep encoding a novel nidogen domain protein.

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Leimeister C, Schumacher N, Diez H, and Gessler M

Developmental dynamics : an official publication of the American Association of Anatomists 230(2):371-7, 2004 Jun - Who cited this? | PubMed ID: 15162516 | Fulltext

Overlapping expression pattern of the actin organizers Spir-1 and formin-2 in the developing mouse nervous system and the adult brain.

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Schumacher N, Borawski JM, Leberfinger CB, Gessler M, and Kerkhoff E

Gene expression patterns : GEP 4(3):249-55, 2004 May - Who cited this? | PubMed ID: 15053972 | Fulltext

The Notch target genes Hey1 and Hey2 are required for embryonic vascular development.

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Fischer A, Schumacher N, Maier M, Sendtner M, and Gessler M

Genes & development 18(8):901-11, 2004 Apr 15 - Who cited this? | PubMed ID: 15107403 | Fulltext

Identification of BOIP, a novel cDNA highly expressed during spermatogenesis that encodes a protein interacting with the orange domain of the hairy-related transcription factor HRT1/Hey1 in Xenopus and mouse.

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Van Wayenbergh R, Taelman V, Pichon B, Fischer A, Kricha S, Gessler M, Christophe D, and Bellefroid EJ

Developmental dynamics : an official publication of the American Association of Anatomists 228(4):716-25, 2003 Dec - Who cited this? | PubMed ID: 14648848 | Fulltext

Characterization of hey bHLH genes in teleost fish.

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Winkler C, Elmasri H, Klamt B, Volff JN, and Gessler M

Development genes and evolution 213(11):541-53, 2003 Nov - Who cited this? | PubMed ID: 14593478 | Fulltext

Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.

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Leimeister C, Schumacher N, and Gessler M

Gene expression patterns : GEP 3(5):595-8, 2003 Oct - Who cited this? | PubMed ID: 12971992 | Fulltext

Hey genes in cardiovascular development.

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Fischer A and Gessler M

Trends in cardiovascular medicine 13(6):221-6, 2003 Aug - Who cited this? | PubMed ID: 12922017 | Fulltext

Mouse gridlock: no aortic coarctation or deficiency, but fatal cardiac defects in Hey2 -/- mice.

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Gessler M, Knobeloch KP, Helisch A, Amann K, Schumacher N, Rohde E, Fischer A, and Leimeister C

Current biology : CB 12(18):1601-4, 2002 Sep 17 - Who cited this? | PubMed ID: 12372253 | Fulltext

Developmental expression and biochemical characterization of Emu family members.

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Leimeister C, Steidl C, Schumacher N, Erhard S, and Gessler M

Developmental biology 249(2):204, 2002 Sep 15 - Who cited this? | PubMed ID: 12221002 | Fulltext

Placental alpha(2)-adrenoceptors control vascular development at the interface between mother and embryo.

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Philipp M, Brede ME, Hadamek K, Gessler M, Lohse MJ, and Hein L

Nature genetics 31(3):311-5, 2002 Jul - Who cited this? | PubMed ID: 12068299 | Fulltext

Hey bHLH factors in cardiovascular development.

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Fischer A, Leimeister C, Winkler C, Schumacher N, Klamt B, Elmasri H, Steidl C, Maier M, Knobeloch KP, Amann K, Helisch A, Sendtner M, and Gessler M

Cold Spring Harbor symposia on quantitative biology 67:63-70, 2002 - Who cited this? | PubMed ID: 12858525 | Fulltext

A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease.

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Bruneau BG, Nemer G, Schmitt JP, Charron F, Robitaille L, Caron S, Conner DA, Gessler M, Nemer M, Seidman CE, and Seidman JG

Cell 106(6):709-21, 2001 Sep 21 - Who cited this? | PubMed ID: 11572777 | Fulltext

Gain of 1q is associated with adverse outcome in favorable histology Wilms' tumors.

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Hing S, Lu YJ, Summersgill B, King-Underwood L, Nicholson J, Grundy P, Grundy R, Gessler M, Shipley J, and Pritchard-Jones K

The American journal of pathology 158(2):393-8, 2001 Feb - Who cited this? | PubMed ID: 11159177 | Fulltext

Analysis of HeyL expression in wild-type and Notch pathway mutant mouse embryos.

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Leimeister C, Schumacher N, Steidl C, and Gessler M

Mechanisms of development 98(1-2):175-8, 2000 Nov - Who cited this? | PubMed ID: 11044625 | Fulltext

Oscillating expression of c-Hey2 in the presomitic mesoderm suggests that the segmentation clock may use combinatorial signaling through multiple interacting bHLH factors.

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Leimeister C, Dale K, Fischer A, Klamt B, Hrabe de Angelis M, Radtke F, McGrew MJ, Pourquié O, and Gessler M

Developmental biology 227(1):91-103, 2000 Nov 1 - Who cited this? | PubMed ID: 11076679 | Fulltext

Comparative analysis of the human and mouse Hey1 promoter: Hey genes are new Notch target genes.

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Maier MM and Gessler M

Biochemical and biophysical research communications 275(2):652-60, 2000 Aug 28 - Who cited this? | PubMed ID: 10964718 | Fulltext

Activation of the Notch pathway in the hair cortex leads to aberrant differentiation of the adjacent hair-shaft layers.

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Lin MH, Leimeister C, Gessler M, and Kopan R

Development (Cambridge, England) 127(11):2421-32, 2000 Jun - Who cited this? | PubMed ID: 10804183 | Fulltext

Characterization of the human and mouse HEY1, HEY2, and HEYL genes: cloning, mapping, and mutation screening of a new bHLH gene family.

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Steidl C, Leimeister C, Klamt B, Maier M, Nanda I, Dixon M, Clarke R, Schmid M, and Gessler M

Genomics 66(2):195-203, 2000 Jun 1 - Who cited this? | PubMed ID: 10860664 | Fulltext

Molecular analysis of E-cadherin and cadherin-11 in Wilms' tumours.

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Schulz S, Becker KF, Braungart E, Reichmuth C, Klamt B, Becker I, Atkinson M, Gessler M, and Höfler H

The Journal of pathology 191(2):162-9, 2000 Jun - Who cited this? | PubMed ID: 10861576 | Fulltext

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