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Papers authored by Gautel M

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Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover.

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Waters S, Marchbank K, Solomon E, Whitehouse C, and Gautel M

FEBS letters 583(12):1846-52, 2009 Jun 18 - Who cited this? | PubMed ID: 19427866 | Fulltext

Myosin binding protein C positioned to play a key role in regulation of muscle contraction: structure and interactions of domain C1.

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Ababou A, Rostkova E, Mistry S, Le Masurier C, Gautel M, and Pfuhl M

Journal of molecular biology 384(3):615-30, 2008 Dec 19 - Who cited this? | PubMed ID: 18926831 | Fulltext

Mechanoenzymatics of titin kinase.

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Puchner EM, Alexandrovich A, Kho AL, Hensen U, Schäfer LV, Brandmeier B, Gräter F, Grubmüller H, Gaub HE, and Gautel M

Proceedings of the National Academy of Sciences of the United States of America, 2008 Sep 2 - Who cited this? | PubMed ID: 18765796 | Fulltext

Comparing proteins by their unfolding pattern.

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Puchner EM, Franzen G, Gautel M, and Gaub HE

Biophysical journal 95(1):426-34, 2008 Jul - Who cited this? | PubMed ID: 18550806 | Fulltext

Interactions with titin and myomesin target obscurin and obscurin-like 1 to the M-band - implications for hereditary myopathies.

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Fukuzawa A, Lange S, Holt M, Vihola A, Carmignac V, Ferreiro A, Udd B, and Gautel M

Journal of cell science 121(Pt 11):1841, 2008 Jun 1 - Who cited this? | PubMed ID: 18477606 | Fulltext

The sarcomere and sarcomerogenesis.

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Ehler E and Gautel M

Advances in experimental medicine and biology 642:1-14, 2008 - Who cited this? | PubMed ID: 19181089 | Fulltext

The sarcomere and the nucleus: functional links to hypertrophy, atrophy and sarcopenia.

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Gautel M

Advances in experimental medicine and biology 642:176-91, 2008 - Who cited this? | PubMed ID: 19181101 | Fulltext

Rigid conformation of an immunoglobulin domain tandem repeat in the A-band of the elastic muscle protein titin.

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Müller S, Lange S, Gautel M, and Wilmanns M

Journal of molecular biology 371(2):469-80, 2007 Aug 10 - Who cited this? | PubMed ID: 17574571 | Fulltext

C-terminal titin deletions cause a novel early-onset myopathy with fatal cardiomyopathy.

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Carmignac V, Salih MA, Quijano-Roy S, Marchand S, Al Rayess MM, Mukhtar MM, Urtizberea JA, Labeit S, Guicheney P, Leturcq F, Gautel M, Fardeau M, Campbell KP, Richard I, Estournet B, and Ferreiro A

Annals of neurology 61(4):340-51, 2007 Apr - Who cited this? | PubMed ID: 17444505 | Fulltext

Dissecting the N-terminal myosin binding site of human cardiac myosin-binding protein C. Structure and myosin binding of domain C2.

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Ababou A, Gautel M, and Pfuhl M

The Journal of biological chemistry 282(12):9204-15, 2007 Mar 23 - Who cited this? | PubMed ID: 17192269 | Fulltext

Crystal structures of human cardiac beta-myosin II S2-Delta provide insight into the functional role of the S2 subfragment.

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Blankenfeldt W, Thomä NH, Wray JS, Gautel M, and Schlichting I

Proceedings of the National Academy of Sciences of the United States of America 103(47):17713-7, 2006 Nov 21 - Who cited this? | PubMed ID: 17095604 | Fulltext

Targeted homozygous deletion of M-band titin in cardiomyocytes prevents sarcomere formation.

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Musa H, Meek S, Gautel M, Peddie D, Smith AJ, and Peckham M

Journal of cell science 119(Pt 20):4322, 2006 Oct 15 - Who cited this? | PubMed ID: 17038546 | Fulltext

Evidence for a dimeric assembly of two titin/telethonin complexes induced by the telethonin C-terminus.

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Pinotsis N, Petoukhov M, Lange S, Svergun D, Zou P, Gautel M, and Wilmanns M

Journal of structural biology 155(2):239, 2006 Aug - Who cited this? | PubMed ID: 16713295 | Fulltext

Activation of myocardial contraction by the N-terminal domains of myosin binding protein-C.

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Herron TJ, Rostkova E, Kunst G, Chaturvedi R, Gautel M, and Kentish JC

Circulation research 98(10):1290, 2006 May 26 - Who cited this? | PubMed ID: 16614305 | Fulltext

Palindromic assembly of the giant muscle protein titin in the sarcomeric Z-disk.

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Zou P, Pinotsis N, Lange S, Song YH, Popov A, Mavridis I, Mayans OM, Gautel M, and Wilmanns M

Nature 439(7073):229, 2006 Jan 12 - Who cited this? | PubMed ID: 16407954 | Fulltext

From A to Z and back? Multicompartment proteins in the sarcomere.

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Lange S, Ehler E, and Gautel M

Trends in cell biology 16(1):11-8, 2006 Jan - Who cited this? | PubMed ID: 16337382 | Fulltext

The kinase domain of titin controls muscle gene expression and protein turnover.

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Lange S, Xiang F, Yakovenko A, Vihola A, Hackman P, Rostkova E, Kristensen J, Brandmeier B, Franzen G, Hedberg B, Gunnarsson LG, Hughes SM, Marchand S, Sejersen T, Richard I, Edström L,

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Science (New York, N.Y.) 308(5728):1599, 2005 Jun 10 - Who cited this? | PubMed ID: 15802564 | Fulltext

Calpain 1-titin interactions concentrate calpain 1 in the Z-band edges and in the N2-line region within the skeletal myofibril.

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Raynaud F, Fernandez E, Coulis G, Aubry L, Vignon X, Bleimling N, Gautel M, Benyamin Y, and Ouali A

The FEBS journal 272(10):2578, 2005 May - Who cited this? | PubMed ID: 15885106 | Fulltext

The crystal structure of the actin binding domain from alpha-actinin in its closed conformation: structural insight into phospholipid regulation of alpha-actinin.

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Franzot G, Sjöblom B, Gautel M, and Djinović Carugo K

Journal of molecular biology 348(1):151-65, 2005 Apr 22 - Who cited this? | PubMed ID: 15808860 | Fulltext

Mechanically induced titin kinase activation studied by force-probe molecular dynamics simulations.

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Gräter F, Shen J, Jiang H, Gautel M, and Grubmüller H

Biophysical journal 88(2):790-804, 2005 Feb - Who cited this? | PubMed ID: 15531631 | Fulltext

Complete human gene structure of obscurin: implications for isoform generation by differential splicing.

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Fukuzawa A, Idowu S, and Gautel M

Journal of muscle research and cell motility 26(6-8):427-34, 2005 - Who cited this? | PubMed ID: 16625316 | Fulltext

Protein kinase D is a novel mediator of cardiac troponin I phosphorylation and regulates myofilament function.

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Haworth RS, Cuello F, Herron TJ, Franzen G, Kentish JC, Gautel M, and Avkiran M

Circulation research 95(11):1091, 2004 Nov 26 - Who cited this? | PubMed ID: 15514163 | Fulltext

Binding of myosin binding protein-C to myosin subfragment S2 affects contractility independent of a tether mechanism.

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Harris SP, Rostkova E, Gautel M, and Moss RL

Circulation research 95(9):930-6, 2004 Oct 29 - Who cited this? | PubMed ID: 15472117 | Fulltext

The elasticity of single titin molecules using a two-bead optical tweezers assay.

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Leake MC, Wilson D, Gautel M, and Simmons RM

Biophysical journal 87(2):1112-35, 2004 Aug - Who cited this? | PubMed ID: 15298915 | Fulltext

Sequence specific assignment of domain C1 of the N-terminal myosin-binding site of human cardiac myosin binding protein C (MyBP-C).

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Ababou A, Zhou L, Gautel M, and Pfuhl M

Journal of biomolecular NMR 29(3):431-2, 2004 Jul - Who cited this? | PubMed ID: 15213454 | Fulltext

Association of the chaperone alphaB-crystallin with titin in heart muscle.

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Bullard B, Ferguson C, Minajeva A, Leake MC, Gautel M, Labeit D, Ding L, Labeit S, Horwitz J, Leonard KR, and Linke WA

The Journal of biological chemistry 279(9):7917-24, 2004 Feb 27 - Who cited this? | PubMed ID: 14676215 | Fulltext

Myofibrillar tightly bound calcium in skeletal muscle fibers: a possible role of this cation in titin strands aggregation.

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Coulis G, Sentandreu MA, Bleimling N, Gautel M, Benyamin Y, and Ouali A

FEBS letters 556(1-3):271-5, 2004 Jan 2 - Who cited this? | PubMed ID: 14706862 | Fulltext

A targeted deletion of the C-terminal end of titin, including the titin kinase domain, impairs myofibrillogenesis.

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Miller G, Musa H, Gautel M, and Peckham M

Journal of cell science 116(Pt 23):4811, 2003 Dec 1 - Who cited this? | PubMed ID: 14600266 | Fulltext

Structure, stability and dynamics of the central domain of cardiac myosin binding protein C (MyBP-C): implications for multidomain assembly and causes for cardiomyopathy.

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Idowu SM, Gautel M, Perkins SJ, and Pfuhl M

Journal of molecular biology 329(4):745-61, 2003 Jun 13 - Who cited this? | PubMed ID: 12787675 | Fulltext

Solution scattering suggests cross-linking function of telethonin in the complex with titin.

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Zou P, Gautel M, Geerlof A, Wilmanns M, Koch MH, and Svergun DI

The Journal of biological chemistry 278(4):2636, 2003 Jan 24 - Who cited this? | PubMed ID: 12446666 | Fulltext

Filamin C accumulation is a strong but nonspecific immunohistochemical marker of core formation in muscle.

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Bönnemann CG, Thompson TG, van der Ven PF, Goebel HH, Warlo I, Vollmers B, Reimann J, Herms J, Gautel M, Takada F, Beggs AH, Fürst DO, Kunkel LM, Hanefeld F, and Schröder R

Journal of the neurological sciences 206(1):71-8, 2003 Jan 15 - Who cited this? | PubMed ID: 12480088 | Fulltext

Transient association of titin and myosin with microtubules in nascent myofibrils directed by the MURF2 RING-finger protein.

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Pizon V, Iakovenko A, Van Der Ven PF, Kelly R, Fatu C, Fürst DO, Karsenti E, and Gautel M

Journal of cell science 115(Pt 23):4469-82, 2002 Dec 1 - Who cited this? | PubMed ID: 12414993 | Fulltext

The spectrin repeat: a structural platform for cytoskeletal protein assemblies.

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Djinovic-Carugo K, Gautel M, Ylänne J, and Young P

FEBS letters 513(1):119-23, 2002 Feb 20 - Who cited this? | PubMed ID: 11911890 | Fulltext

Sequence specific resonance assignment of the central domain of cardiac myosin binding protein C (MyBP-C).

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Idowu SM, Gautel M, and Pfuhl M

Journal of biomolecular NMR 22(2):199-200, 2002 Feb - Who cited this? | PubMed ID: 11883787 | Fulltext

PEVK domain of titin: an entropic spring with actin-binding properties.

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Linke WA, Kulke M, Li H, Fujita-Becker S, Neagoe C, Manstein DJ, Gautel M, and Fernandez JM

Journal of structural biology 137(1-2):194-205, 2002 - Who cited this? | PubMed ID: 12064946 | Fulltext

Interaction between PEVK-titin and actin filaments: origin of a viscous force component in cardiac myofibrils.

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Kulke M, Fujita-Becker S, Rostkova E, Neagoe C, Labeit D, Manstein DJ, Gautel M, and Linke WA

Circulation research 89(10):874-81, 2001 Nov 9 - Who cited this? | PubMed ID: 11701614 | Fulltext

Obscurin, a giant sarcomeric Rho guanine nucleotide exchange factor protein involved in sarcomere assembly.

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Young P, Ehler E, and Gautel M

The Journal of cell biology 154(1):123-36, 2001 Jul 9 - Who cited this? | PubMed ID: 11448995 | Fulltext

Structural evidence for a possible role of reversible disulphide bridge formation in the elasticity of the muscle protein titin.

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Mayans O, Wuerges J, Canela S, Gautel M, and Wilmanns M

Structure (London, England : 1993) 9(4):331-40, 2001 Apr 4 - Who cited this? | PubMed ID: 11525170 | Fulltext

Kinase recognition by calmodulin: modeling the interaction with the autoinhibitory region of human cardiac titin kinase.

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Amodeo P, Castiglione Morelli MA, Strazzullo G, Fucile P, Gautel M, and Motta A

Journal of molecular biology 306(1):81-95, 2001 Feb 9 - Who cited this? | PubMed ID: 11178895 | Fulltext

Early and selective disappearance of telethonin protein from the sarcomere in neurogenic atrophy.

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Schröder R, Reimann J, Iakovenko A, Mues A, Bönnemann CG, Matten J, and Gautel M

Journal of muscle research and cell motility 22(3):259, 2001 - Who cited this? | PubMed ID: 11763198 | Fulltext

The interaction of titin and alpha-actinin is controlled by a phospholipid-regulated intramolecular pseudoligand mechanism.

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Young P and Gautel M

The EMBO journal 19(23):6331-40, 2000 Dec 1 - Who cited this? | PubMed ID: 11101506 | Fulltext

Activation of calcium/calmodulin regulated kinases.

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Wilmann M, Gautel M, and Mayans O

Cellular and molecular biology (Noisy-le-Grand, France) 46(5):883-94, 2000 Jul - Who cited this? | PubMed ID: 10976872 | Fulltext

A functional knock-out of titin results in defective myofibril assembly.

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van der Ven PF, Bartsch JW, Gautel M, Jockusch H, and Fürst DO

Journal of cell science 113 ( Pt 8):1405-14, 2000 Apr - Who cited this? | PubMed ID: 10725223 | Fulltext

A newly created splice donor site in exon 25 of the MyBP-C gene is responsible for inherited hypertrophic cardiomyopathy with incomplete disease penetrance.

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Moolman JA, Reith S, Uhl K, Bailey S, Gautel M, Jeschke B, Fischer C, Ochs J, McKenna WJ, Klues H, and Vosberg HP

Circulation 101(12):1396-402, 2000 Mar 28 - Who cited this? | PubMed ID: 10736283 | Fulltext

Characterization of muscle filamin isoforms suggests a possible role of gamma-filamin/ABP-L in sarcomeric Z-disc formation.

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van der Ven PF, Obermann WM, Lemke B, Gautel M, Weber K, and Fürst DO

Cell motility and the cytoskeleton 45(2):149-62, 2000 Feb - Who cited this? | PubMed ID: 10658210 | Fulltext

Myosin binding protein C, a phosphorylation-dependent force regulator in muscle that controls the attachment of myosin heads by its interaction with myosin S2.

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Kunst G, Kress KR, Gruen M, Uttenweiler D, Gautel M, and Fink RH

Circulation research 86(1):51-8, 2000 - Who cited this? | PubMed ID: 10625305 | Fulltext

Unfolding forces of titin and fibronectin domains directly measured by AFM.

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Rief M, Gautel M, and Gaub HE

Advances in experimental medicine and biology 481:129-36; discussion 137-41, 2000 - Who cited this? | PubMed ID: 10987070 | Fulltext

Structure of the alpha-actinin rod: molecular basis for cross-linking of actin filaments.

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Djinović-Carugo K, Young P, Gautel M, and Saraste M

Cell 98(4):537-46, 1999 Aug 20 - Who cited this? | PubMed ID: 10481917 | Fulltext

I-band titin in cardiac muscle is a three-element molecular spring and is critical for maintaining thin filament structure.

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Linke WA, Rudy DE, Centner T, Gautel M, Witt C, Labeit S, and Gregorio CC

The Journal of cell biology 146(3):631-44, 1999 Aug 9 - Who cited this? | PubMed ID: 10444071 | Fulltext

cAPK-phosphorylation controls the interaction of the regulatory domain of cardiac myosin binding protein C with myosin-S2 in an on-off fashion.

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Gruen M, Prinz H, and Gautel M

FEBS letters 453(3):254-9, 1999 Jun 25 - Who cited this? | PubMed ID: 10405155 | Fulltext

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