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Papers authored by Garcia KC

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Structural basis of receptor sharing by interleukin 17 cytokines.

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Ely LK, Fischer S, and Garcia KC

Nature immunology 10(12):1245-51, 2009 Dec - Who cited this? | PubMed ID: 19838198 | Fulltext

Different Strategies Adopted by Kb and Ld to Generate T Cell Specificity Directed against Their Respective Bound Peptides.

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Bowerman NA, Colf LA, Garcia KC, and Kranz DM

The Journal of biological chemistry 284(47):32551-61, 2009 Nov 20 - Who cited this? | PubMed ID: 19755422 | Fulltext

Gabapentin Receptor alpha2delta-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis.

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Eroglu C, Allen NJ, Susman MW, O'Rourke NA, Park CY, Ozkan E, Chakraborty C, Mulinyawe SB, Annis DS, Huberman AD, Green EM, Lawler J, Dolmetsch R, Garcia KC, Smith SJ, Luo ZD,

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Cell 139(2):380-92, 2009 Oct 16 - Who cited this? | PubMed ID: 19818485 | Fulltext

Distinct Structural Requirements for Interleukin-4 (IL-4) and IL-13 Binding to the Shared IL-13 Receptor Facilitate Cellular Tuning of Cytokine Responsiveness.

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Ito T, Suzuki S, Kanaji S, Shiraishi H, Ohta S, Arima K, Tanaka G, Tamada T, Honjo E, Garcia KC, Kuroki R, and Izuhara K

The Journal of biological chemistry 284(36):24289-96, 2009 Sep 4 - Who cited this? | PubMed ID: 19586918 | Fulltext

Mechanistic and structural insights into the proteolytic activation of Vibrio cholerae MARTX toxin.

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Shen A, Lupardus PJ, Albrow VE, Guzzetta A, Powers JC, Garcia KC, and Bogyo M

Nature chemical biology 5(7):469-78, 2009 Jul - Who cited this? | PubMed ID: 19465933 | Fulltext

IL1B polymorphisms modulate cystic fibrosis lung disease.

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Levy H, Murphy A, Zou F, Gerard C, Klanderman B, Schuemann B, Lazarus R, García KC, Celedón JC, Drumm M, Dahmer M, Quasney M, Schneck K, Reske M, Knowles MR, Pier GB,

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Pediatric pulmonology 44(6):580-93, 2009 Jun - Who cited this? | PubMed ID: 19431193 | Fulltext

CPDadh: A new peptidase family homologous to the cysteine protease domain in bacterial MARTX toxins.

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Pei J, Lupardus PJ, Garcia KC, and Grishin NV

Protein science : a publication of the Protein Society 18(4):856-62, 2009 Apr - Who cited this? | PubMed ID: 19309740 | Fulltext

STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1.

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Park CY, Hoover PJ, Mullins FM, Bachhawat P, Covington ED, Raunser S, Walz T, Garcia KC, Dolmetsch RE, and Lewis RS

Cell 136(5):876-90, 2009 Mar 6 - Who cited this? | PubMed ID: 19249086 | Fulltext

Structural biology of shared cytokine receptors.

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Wang X, Lupardus P, Laporte SL, and Garcia KC

Annual review of immunology 27:29-60, 2009 - Who cited this? | PubMed ID: 18817510 | Fulltext

Distinct CDR3 Conformations in TCRs Determine the Level of Cross-Reactivity for Diverse Antigens, but Not the Docking Orientation.

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Jones LL, Colf LA, Stone JD, Garcia KC, and Kranz DM

Journal of immunology (Baltimore, Md. : 1950) 181(9):6255-64, 2008 Nov 1 - Who cited this? | PubMed ID: 18941216 | Fulltext

Different Thermodynamic Binding Mechanisms and Peptide Fine Specificities Associated with a Panel of Structurally Similar High-Affinity T Cell Receptors.

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Jones LL, Colf LA, Bankovich AJ, Stone JD, Gao YG, Chan CM, Huang RH, Garcia KC, and Kranz DM

Biochemistry, 2008 Oct 31 - Who cited this? | PubMed ID: 18973345 | Fulltext

Small molecule-induced allosteric activation of the Vibrio cholerae RTX cysteine protease domain.

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Lupardus PJ, Shen A, Bogyo M, and Garcia KC

Science (New York, N.Y.) 322(5899):265-8, 2008 Oct 10 - Who cited this? | PubMed ID: 18845756 | Fulltext

Structural Organization of a Full-Length gp130/LIF-R Cytokine Receptor Transmembrane Complex.

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Skiniotis G, Lupardus PJ, Martick M, Walz T, and Garcia KC

Molecular cell 31(5):737-48, 2008 Sep 5 - Who cited this? | PubMed ID: 18775332 | Fulltext

BacMam system for high-level expression of recombinant soluble and membrane glycoproteins for structural studies.

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Dukkipati A, Park HH, Waghray D, Fischer S, and Garcia KC

Protein expression and purification, 2008 Aug 22 - Who cited this? | PubMed ID: 18782620 | Fulltext

The Structure of Interleukin-23 Reveals the Molecular Basis of p40 Subunit Sharing with Interleukin-12.

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Lupardus PJ and Garcia KC

Journal of molecular biology, 2008 Jul 25 - Who cited this? | PubMed ID: 18680750 | Fulltext

An autonomous CDR3delta is sufficient for recognition of the nonclassical MHC class I molecules T10 and T22 by gammadelta T cells.

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Adams EJ, Strop P, Shin S, Chien YH, and Garcia KC

Nature immunology 9(7):777, 2008 Jul - Who cited this? | PubMed ID: 18516039 | Fulltext

Predictors of mucoid Pseudomonas colonization in cystic fibrosis patients.

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Levy H, Kalish LA, Cannon CL, García KC, Gerard C, Goldmann D, Pier GB, Weiss ST, and Colin AA

Pediatric pulmonology 43(5):463-71, 2008 May - Who cited this? | PubMed ID: 18361452 | Fulltext

Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system.

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LaPorte SL, Juo ZS, Vaclavikova J, Colf LA, Qi X, Heller NM, Keegan AD, and Garcia KC

Cell 132(2):259-72, 2008 Jan 25 - Who cited this? | PubMed ID: 18243101 | Fulltext

Structure of the measles virus hemagglutinin.

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Colf LA, Juo ZS, and Garcia KC

Nature structural & molecular biology 14(12):1227, 2007 Dec - Who cited this? | PubMed ID: 18026116 | Fulltext

Posttranslational regulation of I-Ed by affinity for CLIP.

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Rinderknecht CH, Belmares MP, Catanzarite TL, Bankovich AJ, Holmes TH, Garcia KC, Nanda NK, Busch R, Kovats S, and Mellins ED

Journal of immunology (Baltimore, Md. : 1950) 179(9):5907, 2007 Nov 1 - Who cited this? | PubMed ID: 17947664 | Fulltext

Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'.

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Feng D, Bond CJ, Ely LK, Maynard J, and Garcia KC

Nature immunology 8(9):975, 2007 Sep - Who cited this? | PubMed ID: 17694060 | Fulltext

Elucidation of the interleukin-15 binding site on its alpha receptor by NMR.

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Hanick NA, Rickert M, Varani L, Bankovich AJ, Cochran JR, Kim DM, Surh CD, and Garcia KC

Biochemistry 46(33):9453, 2007 Aug 21 - Who cited this? | PubMed ID: 17655329 | Fulltext

Solution mapping of T cell receptor docking footprints on peptide-MHC.

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Varani L, Bankovich AJ, Liu CW, Colf LA, Jones LL, Kranz DM, Puglisi JD, and Garcia KC

Proceedings of the National Academy of Sciences of the United States of America 104(32):13080, 2007 Aug 7 - Who cited this? | PubMed ID: 17670943 | Fulltext

Polyspecificity of T cell and B cell receptor recognition.

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Wucherpfennig KW, Allen PM, Celada F, Cohen IR, De Boer R, Garcia KC, Goldstein B, Greenspan R, Hafler D, Hodgkin P, Huseby ES, Krakauer DC, Nemazee D, Perelson AS, Pinilla C, Strong RK,

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Seminars in immunology 19(4):216, 2007 Aug - Who cited this? | PubMed ID: 17398114 | Fulltext

Structural elucidation of the m157 mouse cytomegalovirus ligand for Ly49 natural killer cell receptors.

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Adams EJ, Juo ZS, Venook RT, Boulanger MJ, Arase H, Lanier LL, and Garcia KC

Proceedings of the National Academy of Sciences of the United States of America 104(24):10128-33, 2007 Jun 12 - Who cited this? | PubMed ID: 17537914 | Fulltext

Structural insight into pre-B cell receptor function.

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Bankovich AJ, Raunser S, Juo ZS, Walz T, Davis MM, and Garcia KC

Science (New York, N.Y.) 316(5822):291, 2007 Apr 13 - Who cited this? | PubMed ID: 17431183 | Fulltext

How a single T cell receptor recognizes both self and foreign MHC.

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Colf LA, Bankovich AJ, Hanick NA, Bowerman NA, Jones LL, Kranz DM, and Garcia KC

Cell 129(1):135, 2007 Apr 6 - Who cited this? | PubMed ID: 17418792 | Fulltext

Graded expression of semaphorin-1a cell-autonomously directs dendritic targeting of olfactory projection neurons.

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Komiyama T, Sweeney LB, Schuldiner O, Garcia KC, and Luo L

Cell 128(2):399-410, 2007 Jan 26 - Who cited this? | PubMed ID: 17254975 | Fulltext

Structural and mechanistic insights into nerve growth factor interactions with the TrkA and p75 receptors.

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Wehrman T, He X, Raab B, Dukipatti A, Blau H, and Garcia KC

Neuron 53(1):25-38, 2007 Jan 4 - Who cited this? | PubMed ID: 17196528 | Fulltext

In vitro reconstitution and preparative purification of complexes between the chemokine receptor CXCR4 and its ligands SDF-1alpha, gp120-CD4 and AMD3100.

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Dukkipati A, Vaclavikova J, Waghray D, and Garcia KC

Protein expression and purification 50(2):203-14, 2006 Dec - Who cited this? | PubMed ID: 16962791 | Fulltext

Engineering and characterization of a stabilized alpha1/alpha2 module of the class I major histocompatibility complex product Ld.

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Jones LL, Brophy SE, Bankovich AJ, Colf LA, Hanick NA, Garcia KC, and Kranz DM

The Journal of biological chemistry 281(35):25734, 2006 Sep 1 - Who cited this? | PubMed ID: 16815841 | Fulltext

Structural determinants of natriuretic peptide receptor specificity and degeneracy.

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He XL, Dukkipati A, and Garcia KC

Journal of molecular biology 361(4):698-714, 2006 Aug 25 - Who cited this? | PubMed ID: 16870210 | Fulltext

Structure of artemin complexed with its receptor GFRalpha3: convergent recognition of glial cell line-derived neurotrophic factors.

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Wang X, Baloh RH, Milbrandt J, and Garcia KC

Structure (London, England : 1993) 14(6):1083, 2006 Jun - Who cited this? | PubMed ID: 16765900 | Fulltext

Deconstructing the form and function of the TCR/CD3 complex.

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Kuhns MS, Davis MM, and Garcia KC

Immunity 24(2):133, 2006 Feb - Who cited this? | PubMed ID: 16473826 | Fulltext

High-level bacterial secretion of single-chain alphabeta T-cell receptors.

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Maynard J, Adams EJ, Krogsgaard M, Petersson K, Liu CW, and Garcia KC

Journal of immunological methods 306(1-2):51-67, 2005 Nov 30 - Who cited this? | PubMed ID: 16198365 | Fulltext

Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors.

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Wang X, Rickert M, and Garcia KC

Science (New York, N.Y.) 310(5751):1159-63, 2005 Nov 18 - Who cited this? | PubMed ID: 16293754 | Fulltext

How the T cell receptor sees antigen--a structural view.

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Garcia KC and Adams EJ

Cell 122(3):333, 2005 Aug 12 - Who cited this? | PubMed ID: 16096054 | Fulltext

The structure of interleukin-2 complexed with its alpha receptor.

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Rickert M, Wang X, Boulanger MJ, Goriatcheva N, and Garcia KC

Science (New York, N.Y.) 308(5727):1477-80, 2005 Jun 3 - Who cited this? | PubMed ID: 15933202 | Fulltext

A new paradigm for hormone recognition and allosteric receptor activation revealed from structural studies of NPR-C.

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He XL, Dukkipati A, Wang X, and Garcia KC

Peptides 26(6):1035-43, 2005 Jun - Who cited this? | PubMed ID: 15911071 | Fulltext

Signaling conformations of the tall cytokine receptor gp130 when in complex with IL-6 and IL-6 receptor.

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Skiniotis G, Boulanger MJ, Garcia KC, and Walz T

Nature structural & molecular biology 12(6):545-51, 2005 Jun - Who cited this? | PubMed ID: 15895091 | Fulltext

Structure of a gammadelta T cell receptor in complex with the nonclassical MHC T22.

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Adams EJ, Chien YH, and Garcia KC

Science (New York, N.Y.) 308(5719):227-31, 2005 Apr 8 - Who cited this? | PubMed ID: 15821084 | Fulltext

Antigen recognition determinants of gammadelta T cell receptors.

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Shin S, El-Diwany R, Schaffert S, Adams EJ, Garcia KC, Pereira P, and Chien YH

Science (New York, N.Y.) 308(5719):252-5, 2005 Apr 8 - Who cited this? | PubMed ID: 15821090 | Fulltext

A TNF receptor family member, TROY, is a coreceptor with Nogo receptor in mediating the inhibitory activity of myelin inhibitors.

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Park JB, Yiu G, Kaneko S, Wang J, Chang J, He XL, Garcia KC, and He Z

Neuron 45(3):345, 2005 Feb 3 - Who cited this? | PubMed ID: 15694321 | Fulltext

Genetic deletion of the Nogo receptor does not reduce neurite inhibition in vitro or promote corticospinal tract regeneration in vivo.

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Zheng B, Atwal J, Ho C, Case L, He XL, Garcia KC, Steward O, and Tessier-Lavigne M

Proceedings of the National Academy of Sciences of the United States of America 102(4):1205-10, 2005 Jan 25 - Who cited this? | PubMed ID: 15647357 | Fulltext

Structure of an autoimmune T cell receptor complexed with class II peptide-MHC: insights into MHC bias and antigen specificity.

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Maynard J, Petersson K, Wilson DH, Adams EJ, Blondelle SE, Boulanger MJ, Wilson DB, and Garcia KC

Immunity 22(1):81, 2005 Jan - Who cited this? | PubMed ID: 15664161 | Fulltext

Structure of a human A-type potassium channel interacting protein DPPX, a member of the dipeptidyl aminopeptidase family.

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Strop P, Bankovich AJ, Hansen KC, Garcia KC, and Brunger AT

Journal of molecular biology 343(4):1055, 2004 Oct 29 - Who cited this? | PubMed ID: 15476821 | Fulltext

Compensatory energetic mechanisms mediating the assembly of signaling complexes between interleukin-2 and its alpha, beta, and gamma(c) receptors.

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Rickert M, Boulanger MJ, Goriatcheva N, and Garcia KC

Journal of molecular biology 339(5):1115-28, 2004 Jun 18 - Who cited this? | PubMed ID: 15178252 | Fulltext

Structure of nerve growth factor complexed with the shared neurotrophin receptor p75.

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He XL and Garcia KC

Science (New York, N.Y.) 304(5672):870-5, 2004 May 7 - Who cited this? | PubMed ID: 15131306 | Fulltext

Peptide register shifting within the MHC groove: theory becomes reality.

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Bankovich AJ, Girvin AT, Moesta AK, and Garcia KC

Molecular immunology 40(14-15):1033, 2004 Feb - Who cited this? | PubMed ID: 15036907 | Fulltext

Specificity and degeneracy of T cells.

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Wilson DB, Wilson DH, Schroder K, Pinilla C, Blondelle S, Houghten RA, and Garcia KC

Molecular immunology 40(14-15):1047-55, 2004 Feb - Who cited this? | PubMed ID: 15036909 | Fulltext

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