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Papers authored by Galdzicki Z

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Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1.

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Baek KH, Zaslavsky A, Lynch RC, Britt C, Okada Y, Siarey RJ, Lensch MW, Park IH, Yoon SS, Minami T, Korenberg JR, Folkman J, Daley GQ, Aird WC, Galdzicki Z, and Ryeom S

Nature 459(7250):1126-30, 2009 Jun 25 - Who cited this? | PubMed ID: 19458618 | Fulltext

Speeding of miniature excitatory post-synaptic currents in Ts65Dn cultured hippocampal neurons.

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Best TK, Cho-Clark M, Siarey RJ, and Galdzicki Z

Neuroscience letters 438(3):356-61, 2008 Jun 27 - Who cited this? | PubMed ID: 18490108 | Fulltext

Defects in embryonic neurogenesis and initial synapse formation in the forebrain of the Ts65Dn mouse model of Down syndrome.

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Chakrabarti L, Galdzicki Z, and Haydar TF

The Journal of neuroscience : the official journal of the Society for Neuroscience 27(43):11483-95, 2007 Oct 24 - Who cited this? | PubMed ID: 17959791 | Fulltext

Trisomy for the Down syndrome 'critical region' is necessary but not sufficient for brain phenotypes of trisomic mice.

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Olson LE, Roper RJ, Sengstaken CL, Peterson EA, Aquino V, Galdzicki Z, Siarey R, Pletnikov M, Moran TH, and Reeves RH

Human molecular genetics 16(7):774-82, 2007 Apr 1 - Who cited this? | PubMed ID: 17339268 | Fulltext

Ts65Dn, a mouse model of Down syndrome, exhibits increased GABAB-induced potassium current.

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Best TK, Siarey RJ, and Galdzicki Z

Journal of neurophysiology 97(1):892-900, 2007 Jan - Who cited this? | PubMed ID: 17093127 | Fulltext

Altered signaling pathways underlying abnormal hippocampal synaptic plasticity in the Ts65Dn mouse model of Down syndrome.

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Siarey RJ, Kline-Burgess A, Cho M, Balbo A, Best TK, Harashima C, Klann E, and Galdzicki Z

Journal of neurochemistry 98(4):1266, 2006 Aug - Who cited this? | PubMed ID: 16895585 | Fulltext

Abnormal expression of the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) in hippocampus, frontal cortex, and substantia nigra of Ts65Dn mouse: a model of Down syndrome.

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Harashima C, Jacobowitz DM, Witta J, Borke RC, Best TK, Siarey RJ, and Galdzicki Z

The Journal of comparative neurology 494(5):815-33, 2006 Feb 10 - Who cited this? | PubMed ID: 16374808 | Fulltext

Elevated expression of the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) in cerebellar unipolar brush cells of a Down syndrome mouse model.

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Harashima C, Jacobowitz DM, Stoffel M, Chakrabarti L, Haydar TF, Siarey RJ, and Galdzicki Z

Cellular and molecular neurobiology 26(4-6):719-34, 2006 - Who cited this? | PubMed ID: 16783527 | Fulltext

Abnormal synaptic plasticity in the Ts1Cje segmental trisomy 16 mouse model of Down syndrome.

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Siarey RJ, Villar AJ, Epstein CJ, and Galdzicki Z

Neuropharmacology 49(1):122-8, 2005 Jul - Who cited this? | PubMed ID: 15992587 | Fulltext

Understanding mental retardation in Down's syndrome using trisomy 16 mouse models.

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Galdzicki Z and Siarey RJ

Genes, brain, and behavior 2(3):167-78, 2003 Jun - Who cited this? | PubMed ID: 12931790 | Fulltext

Kinetic and mechanistic characterization of NMDA receptor antagonism by replacement and truncation variants of the conantokin peptides.

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Klein RC, Warder SE, Galdzicki Z, Castellino FJ, and Prorok M

Neuropharmacology 41(7):801-10, 2001 Dec - Who cited this? | PubMed ID: 11684144 | Fulltext

Measurement of myo-inositol turnover in phosphatidylinositol: description of a model and mass spectrometric method for cultured cortical neurons.

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Chikhale EG, Balbo A, Galdzicki Z, Rapoport SI, and Shetty HU

Biochemistry 40(37):11114-20, 2001 Sep 18 - Who cited this? | PubMed ID: 11551209 | Fulltext

The amino acid residue at sequence position 5 in the conantokin peptides partially governs subunit-selective antagonism of recombinant N-methyl-D-aspartate receptors.

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Klein RC, Prorok M, Galdzicki Z, and Castellino FJ

The Journal of biological chemistry 276(29):26860-7, 2001 Jul 20 - Who cited this? | PubMed ID: 11335724 | Fulltext

On the cause of mental retardation in Down syndrome: extrapolation from full and segmental trisomy 16 mouse models.

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Galdzicki Z, Siarey R, Pearce R, Stoll J, and Rapoport SI

Brain research. Brain research reviews 35(2):115-45, 2001 Apr - Who cited this? | PubMed ID: 11336779 | Fulltext

Increased expression of NR2A subunit does not alter NMDA-evoked responses in cultured fetal trisomy 16 mouse hippocampal neurons.

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Klein RC, Siarey RJ, Caruso A, Rapoport SI, Castellino FJ, and Galdzicki Z

Journal of neurochemistry 76(6):1663-9, 2001 Mar - Who cited this? | PubMed ID: 11259484 | Fulltext

Abnormal chloride and potassium conductances in cultured embryonic tongue muscle from trisomy 16 mouse.

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Peng S, Rapoport SI, Pearce RJ, and Galdzicki Z

Brain research. Developmental brain research 122(2):193-7, 2000 Aug 30 - Who cited this? | PubMed ID: 10960688 | Fulltext

Ts65Dn mouse, a Down syndrome model, exhibits elevated myo-inositol in selected brain regions and peripheral tissues.

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Shetty HU, Siarey RJ, Galdzicki Z, Stoll J, and Rapoport SI

Neurochemical research 25(4):431, 2000 Apr - Who cited this? | PubMed ID: 10823574 | Fulltext

Brain myo-inositol level is elevated in Ts65Dn mouse and reduced after lithium treatment.

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Huang W, Galdzicki Z, van Gelderen P, Balbo A, Chikhale EG, Schapiro MB, and Rapoport SI

Neuroreport 11(3):445-8, 2000 Feb 28 - Who cited this? | PubMed ID: 10718292 | Fulltext

A positive-feedback model for the loss of acetylcholine in Alzheimer's disease.

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Ehrenstein G, Galdzicki Z, and Lange GD

Annals of the New York Academy of Sciences 899:283-91, 2000 - Who cited this? | PubMed ID: 10863547 | Fulltext

Inhibition of NMDA-induced currents by conantokin-G and conantokin-T in cultured embryonic murine hippocampal neurons.

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Klein RC, Galdzicki Z, and Castellino FJ

Neuropharmacology 38(12):1819-29, 1999 Dec - Who cited this? | PubMed ID: 10608277 | Fulltext

Increased synaptic depression in the Ts65Dn mouse, a model for mental retardation in Down syndrome.

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Siarey RJ, Carlson EJ, Epstein CJ, Balbo A, Rapoport SI, and Galdzicki Z

Neuropharmacology 38(12):1917-20, 1999 Dec - Who cited this? | PubMed ID: 10608287 | Fulltext

Activator protein-1 DNA binding activation by hydrogen peroxide in neuronal and astrocytic primary cultures of trisomy-16 and diploid mice.

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Scortegagna M, Galdzicki Z, Rapoport SI, and Hanbauer I

Brain research. Molecular brain research 73(1-2):144-50, 1999 Nov 10 - Who cited this? | PubMed ID: 10581408 | Fulltext

The ultrastructural effects of beta-amyloid peptide on cultured PC12 cells: changes in cytoplasmic and intramembranous features.

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Lane NJ, Balbo A, Fukuyama R, Rapoport SI, and Galdzicki Z

Journal of neurocytology 27(10):707-18, 1998 Oct - Who cited this? | PubMed ID: 10640186 | Fulltext

Evidence of increased oxidative stress in hippocampal primary cultures of trisomy 16 mouse. Studies on metallothionein-I/II.

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Hanbauer I, Galdzicki Z, Rapoport SI, and Scortegagna M

Restorative neurology and neuroscience 12(2-3):87-93, 1998 Jun - Who cited this? | PubMed ID: 12671302 | Fulltext

Increased expression of voltage-activated calcium channels in cultured hippocampal neurons from mouse trisomy 16, a model for Down syndrome.

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Galdzicki Z, Coan EJ, Rapoport SI, and Stoll J

Brain research. Molecular brain research 56(1-2):200-6, 1998 May - Who cited this? | PubMed ID: 9602127 | Fulltext

In cortical cultures of trisomy 16 mouse brain the upregulated metallothionein-I/II fails to respond to H2O2 exposure or glutamate receptor stimulation.

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Scortegagna M, Galdzicki Z, Rapoport SI, and Hanbauer I

Brain research 787(2):292-8, 1998 Mar 23 - Who cited this? | PubMed ID: 9518655 | Fulltext

Cerebral cortical astroglia from the trisomy 16 mouse, a model for down syndrome, produce neuronal cholinergic deficits in cell culture.

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Nelson PG, Fitzgerald S, Rapoport SI, Neale EA, Galdzicki Z, Dunlap V, Bowers L, and v Agoston D

Proceedings of the National Academy of Sciences of the United States of America 94(23):12644-8, 1997 Nov 11 - Who cited this? | PubMed ID: 9356503 | Fulltext

Beta-amyloid induced increase in choline flux across PC12 cell membranes.

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Allen DD, Galdzicki Z, Brining SK, Fukuyama R, Rapoport SI, and Smith QR

Neuroscience letters 234(1):71-3, 1997 Sep 26 - Who cited this? | PubMed ID: 9347949 | Fulltext

Responses to NMDA in cultured hippocampal neurons from trisomy 16 embryonic mice.

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Siarey RJ, Coan EJ, Rapoport SI, and Galdzicki Z

Neuroscience letters 232(3):131-4, 1997 Sep 5 - Who cited this? | PubMed ID: 9310297 | Fulltext

The choline-leakage hypothesis for the loss of acetylcholine in Alzheimer's disease.

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Ehrenstein G, Galdzicki Z, and Lange GD

Biophysical journal 73(3):1276-80, 1997 Sep - Who cited this? | PubMed ID: 9284295 | Fulltext

Altered long-term potentiation in the young and old Ts65Dn mouse, a model for Down Syndrome.

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Siarey RJ, Stoll J, Rapoport SI, and Galdzicki Z

Neuropharmacology 36(11-12):1549-54, 1997 - Who cited this? | PubMed ID: 9517425 | Fulltext

Reduced expression of voltage-gated sodium channels in neurons cultured from trisomy 16 mouse hippocampus.

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Stoll J and Galdzicki Z

International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 14(6):749-60, 1996 Oct - Who cited this? | PubMed ID: 8960982 | Fulltext

Brain accumulation of myo-inositol in the trisomy 16 mouse, an animal model of Down's syndrome.

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Shetty HU, Holloway HW, Acevedo LD, and Galdzicki Z

The Biochemical journal 313 ( Pt 1):31-3, 1996 Jan 1 - Who cited this? | PubMed ID: 8546700 | Fulltext

Increased inward current in septal neurons from the trisomy 16 mouse, a model for Down's syndrome.

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Acevedo LD, Galdzicki Z, McIntosh AR, and Rapoport SI

Brain research 701(1-2):89-98, 1995 Dec 1 - Who cited this? | PubMed ID: 8925303 | Fulltext

Decreased sensitivity to nerve growth factor of dorsal root ganglion neurons cultured from mouse trisomy 16, a model of Down's syndrome.

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Pearce R, Galdzicki Z, and Rapoport SI

Brain research 680(1-2):108-16, 1995 May 22 - Who cited this? | PubMed ID: 7663966 | Fulltext

beta-Amyloid polypeptide increases calcium-uptake in PC12 cells: a possible mechanism for its cellular toxicity in Alzheimer's disease.

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Fukuyama R, Wadhwani KC, Galdzicki Z, Rapoport SI, and Ehrenstein G

Brain research 667(2):269-72, 1994 Dec 26 - Who cited this? | PubMed ID: 7697365 | Fulltext

Effects of nerve growth factor on whole-cell currents and other electrical membrane properties in cultured dorsal root ganglion neurons from normal and trisomy 16 mice.

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Coan EJ, Galdzicki Z, and Rapoport SI

Brain research 650(1):161-5, 1994 Jul 4 - Who cited this? | PubMed ID: 7953669 | Fulltext

beta-Amyloid increases choline conductance of PC12 cells: possible mechanism of toxicity in Alzheimer's disease.

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Galdzicki Z, Fukuyama R, Wadhwani KC, Rapoport SI, and Ehrenstein G

Brain research 646(2):332-6, 1994 May 23 - Who cited this? | PubMed ID: 8069685 | Fulltext

Cultured hippocampal neurons from trisomy 16 mouse, a model for Down's syndrome, have an abnormal action potential due to a reduced inward sodium current.

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Galdzicki Z, Coan E, and Rapoport SI

Brain research 604(1-2):69-78, 1993 Feb 26 - Who cited this? | PubMed ID: 8384514 | Fulltext

Development of voltage-dependent ionic currents in rat cerebellar granule cells grown in primary culture.

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Galdzicki Z, Lin F, Moran O, Novelli A, Puia G, and Sciancalepore M

The International journal of neuroscience 56(1-4):193-200, 1991 - Who cited this? | PubMed ID: 1938136 | Fulltext

Low Ca2+-sensitive maxi-K+ channels in human cultured fibroblasts.

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Galietta LJ, Galdzicki Z, and Nobile M

Pflugers Archiv : European journal of physiology 413(1):99-101, 1988 Nov - Who cited this? | PubMed ID: 3217232 | Fulltext

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