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Papers authored by Gajewski T

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PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model.

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Zhang L, Gajewski TF, and Kline J

Blood 114(8):1545-52, 2009 Aug 20 - Who cited this? | PubMed ID: 19417208 | Fulltext

Immune-mediated red cell aplasia after anti-CTLA-4 immunotherapy for metastatic melanoma.

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Gordon IO, Wade T, Chin K, Dickstein J, and Gajewski TF

Cancer immunology, immunotherapy : CII 58(8):1351-3, 2009 Aug - Who cited this? | PubMed ID: 19052742 | Fulltext

CARMA1 controls an early checkpoint in the thymic development of FoxP3+ regulatory T cells.

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Molinero LL, Yang J, Gajewski T, Abraham C, Farrar MA, and Alegre ML

Journal of immunology (Baltimore, Md. : 1950) 182(11):6736-43, 2009 Jun 1 - Who cited this? | PubMed ID: 19454668 | Fulltext

Protein Kinase C{theta} Focusing at the cSMAC Is a Consequence rather than Cause of TCR Signaling and Is Dependent on the MEK/ERK Pathway.

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Praveen K, Zheng Y, Rivas F, and Gajewski TF

Journal of immunology (Baltimore, Md. : 1950) 182(10):6022-30, 2009 May 15 - Who cited this? | PubMed ID: 19414753 | Fulltext

Costimulatory and coinhibitory receptors in anti-tumor immunity.

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Driessens G, Kline J, and Gajewski TF

Immunological reviews 229(1):126-44, 2009 May - Who cited this? | PubMed ID: 19426219 | Fulltext

Chemokine Expression in Melanoma Metastases Associated with CD8+ T-Cell Recruitment.

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Harlin H, Meng Y, Peterson AC, Zha Y, Tretiakova M, Slingluff C, McKee M, and Gajewski TF

Cancer research 69(7):3077-85, 2009 Apr 1 - Who cited this? | PubMed ID: 19293190 | Fulltext

Phase I/II Trial of Tremelimumab in Patients With Metastatic Melanoma.

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Camacho LH, Antonia S, Sosman J, Kirkwood JM, Gajewski TF, Redman B, Pavlov D, Bulanhagui C, Bozon VA, Gomez-Navarro J, and Ribas A

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 27(7):1075-81, 2009 Mar 1 - Who cited this? | PubMed ID: 19139427 | Fulltext

Emerging strategies in regulatory T-cell immunotherapies.

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Gajewski TF, Chesney J, and Curriel TJ

Clinical advances in hematology & oncology : H&O 7(1):1-10; quiz 11-2, 2009 Jan - Who cited this? | PubMed ID: 19288606 | Fulltext

The HLA-A2-restricted PSMA peptide LLHETDSAV is poorly immunogenic in patients with metastatic prostate cancer.

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Knight D, Peterson AC, Rini BI, Harlin H, Gajewski TF, and Stadler WM

The Prostate, 2008 Oct 22 - Who cited this? | PubMed ID: 18942640 | Fulltext

Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8(+) T cells.

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Cham CM, Driessens G, O'Keefe JP, and Gajewski TF

European journal of immunology 38(9):2438, 2008 Sep 15 - Who cited this? | PubMed ID: 18792400 | Fulltext

Melanoma presenting as circulating tumor cells associated with failed angiogenesis.

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Lee RT, Fallarino F, Ashikari A, and Gajewski TF

Melanoma research 18(4):289-94, 2008 Aug - Who cited this? | PubMed ID: 18626315 | Fulltext

Homeostatic proliferation plus regulatory T-cell depletion promotes potent rejection of b16 melanoma.

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Kline J, Brown IE, Zha YY, Blank C, Strickler J, Wouters H, Zhang L, and Gajewski TF

Clinical cancer research : an official journal of the American Association for Cancer Research 14(10):3156-67, 2008 May 15 - Who cited this? | PubMed ID: 18483384 | Fulltext

Use of Cre-adenovirus and CAR transgenic mice for efficient deletion of genes in post-thymic T cells.

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Zha Y, Shah R, Locke F, Wong A, and Gajewski TF

Journal of immunological methods 331(1-2):94-102, 2008 Feb 29 - Who cited this? | PubMed ID: 18177887 | Fulltext

Molecular regulation of T-cell anergy.

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Zheng Y, Zha Y, and Gajewski TF

EMBO reports 9(1):50, 2008 Jan - Who cited this? | PubMed ID: 18174897 | Fulltext

Diagnosis and treatment of Mycoplasma-contaminated cell cultures.

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Harlin H and Gajewski TF

Current protocols in cytometry / editorial board, J. Paul Robinson, managing editor ... [et al.] Appendix 3:3C, 2008 Jan - Who cited this? | PubMed ID: 18770641 | Fulltext

Farnesyltransferase inhibitors inhibit T-cell cytokine production at the posttranscriptional level.

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Marks RE, Ho AW, Robbel C, Kuna T, Berk S, and Gajewski TF

Blood 110(6):1982, 2007 Sep 15 - Who cited this? | PubMed ID: 17545504 | Fulltext

Failure at the effector phase: immune barriers at the level of the melanoma tumor microenvironment.

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Gajewski TF

Clinical cancer research : an official journal of the American Association for Cancer Research 13(18 Pt 1):5256-61, 2007 Sep 15 - Who cited this? | PubMed ID: 17875753 | Fulltext

Report on the ISBTC mini-symposium on biologic effects of targeted therapeutics.

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Atkins MB, Carbone D, Coukos G, Dhodapkar M, Ernstoff MS, Finke J, Gajewski TF, Gollob J, Lotze MT, Storkus W, and Weiner LM

Journal of immunotherapy (Hagerstown, Md. : 1997) 30(6):577-90, 2007 Sep - Who cited this? | PubMed ID: 17667521 | Fulltext

Targeting the primary tumor to generate CTL for the effective eradication of spontaneous metastases.

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Yu P, Lee Y, Wang Y, Liu X, Auh S, Gajewski TF, Schreiber H, You Z, Kaynor C, Wang X, and Fu YX

Journal of immunology (Baltimore, Md. : 1950) 179(3):1960-8, 2007 Aug 1 - Who cited this? | PubMed ID: 17641063 | Fulltext

The expanding universe of regulatory T cell subsets in cancer.

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Gajewski TF

Immunity 27(2):185-7, 2007 Aug - Who cited this? | PubMed ID: 17723212 | Fulltext

An adenoviral vector encoding dominant negative Cbl lowers the threshold for T cell activation in post-thymic T cells.

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Zha Y and Gajewski TF

Cellular immunology 247(2):95-102, 2007 Jun - Who cited this? | PubMed ID: 17897636 | Fulltext

On the TRAIL toward death receptor-based cancer therapeutics.

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Gajewski TF

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 25(11):1305-7, 2007 Apr 10 - Who cited this? | PubMed ID: 17416849 | Fulltext

T cell anergy is reversed by active Ras and is regulated by diacylglycerol kinase-alpha.

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Zha Y, Marks R, Ho AW, Peterson AC, Janardhan S, Brown I, Praveen K, Stang S, Stone JC, and Gajewski TF

Nature immunology 7(11):1166-73, 2006 Nov - Who cited this? | PubMed ID: 17028589 | Fulltext

Homeostatic proliferation as an isolated variable reverses CD8+ T cell anergy and promotes tumor rejection.

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Brown IE, Blank C, Kline J, Kacha AK, and Gajewski TF

Journal of immunology (Baltimore, Md. : 1950) 177(7):4521, 2006 Oct 1 - Who cited this? | PubMed ID: 16982889 | Fulltext

Tumor progression despite massive influx of activated CD8(+) T cells in a patient with malignant melanoma ascites.

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Harlin H, Kuna TV, Peterson AC, Meng Y, and Gajewski TF

Cancer immunology, immunotherapy : CII 55(10):1185-97, 2006 Oct - Who cited this? | PubMed ID: 16468035 | Fulltext

Immune resistance orchestrated by the tumor microenvironment.

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Gajewski TF, Meng Y, Blank C, Brown I, Kacha A, Kline J, and Harlin H

Immunological reviews 213:131-45, 2006 Oct - Who cited this? | PubMed ID: 16972901 | Fulltext

Induction of cytotoxic granules in human memory CD8+ T cell subsets requires cell cycle progression.

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Meng Y, Harlin H, O'Keefe JP, and Gajewski TF

Journal of immunology (Baltimore, Md. : 1950) 177(3):1981-7, 2006 Aug 1 - Who cited this? | PubMed ID: 16849512 | Fulltext

Blockade of PD-L1 (B7-H1) augments human tumor-specific T cell responses in vitro.

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Blank C, Kuball J, Voelkl S, Wiendl H, Becker B, Walter B, Majdic O, Gajewski TF, Theobald M, Andreesen R, and Mackensen A

International journal of cancer. Journal international du cancer 119(2):317-27, 2006 Jul 15 - Who cited this? | PubMed ID: 16482562 | Fulltext

Cross-priming of T cells to intracranial tumor antigens elicits an immune response that fails in the effector phase but can be augmented with local immunotherapy.

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Velicu S, Han Y, Ulasov I, Brown IE, El Andaloussi A, Gajewski TF, and Lesniak MS

Journal of neuroimmunology 174(1-2):74-81, 2006 May - Who cited this? | PubMed ID: 16504307 | Fulltext

Production of t(h)1 and t(h)2 cell lines and clones.

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Fitch FW, Gajewski TF, and Hu-Li J

Current protocols in immunology / edited by John E. Coligan ... [et al.] Chapter 3:Unit3.13, 2006 May - Who cited this? | PubMed ID: 18432972 | Fulltext

An adenoviral vector for probing promoter activity in primary immune cells.

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Tripathi P, Madan R, Chougnet C, Divanovic S, Ma X, Wahl LM, Gajewski T, Karp CL, and Hildeman DA

Journal of immunological methods 311(1-2):19-30, 2006 Apr 20 - Who cited this? | PubMed ID: 16563424 | Fulltext

Innovations and challenges in melanoma: summary statement from the first Cambridge conference.

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Atkins MB, Elder DE, Essner R, Flaherty KT, Gajewski TF, Haluska FG, Hwu P, Keilholz U, Kirkwood JM, Mier JW, Ross MI, Slingluff CL, Sondak VK, Sosman JA, Weinstock MA, and King L

Clinical cancer research : an official journal of the American Association for Cancer Research 12(7 Pt 2):2291, 2006 Apr 1 - Who cited this? | PubMed ID: 16609047 | Fulltext

Identifying and overcoming immune resistance mechanisms in the melanoma tumor microenvironment.

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Gajewski TF

Clinical cancer research : an official journal of the American Association for Cancer Research 12(7 Pt 2):2326, 2006 Apr 1 - Who cited this? | PubMed ID: 16609053 | Fulltext

A randomized phase II trial of interleukin-2 in combination with four different doses of bryostatin-1 in patients with renal cell carcinoma.

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Peterson AC, Harlin H, Karrison T, Vogelzang NJ, Knost JA, Kugler JW, Lester E, Vokes E, Gajewski TF, Stadler WM, and University of Chicago Phase II Consortium

Investigational new drugs 24(2):141-9, 2006 Mar - Who cited this? | PubMed ID: 16514482 | Fulltext

Phase 2 study of the g209-2M melanoma peptide vaccine and low-dose interleukin-2 in advanced melanoma: Cancer and Leukemia Group B 509901.

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Roberts JD, Niedzwiecki D, Carson WE, Chapman PB, Gajewski TF, Ernstoff MS, Hodi FS, Shea C, Leong SP, Johnson J, Zhang D, Houghton A, Haluska FG, and Cancer and Leukemia Group B

Journal of immunotherapy (Hagerstown, Md. : 1997) 29(1):95-101, 2006 - Who cited this? | PubMed ID: 16365605 | Fulltext

Immune suppression in the tumor microenvironment.

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Gajewski TF, Meng Y, and Harlin H

Journal of immunotherapy (Hagerstown, Md. : 1997) 29(3):233-40, 2006 - Who cited this? | PubMed ID: 16699366 | Fulltext

Diagnosis and treatment of Mycoplasma-contaminated cell cultures.

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Harlin H and Gajewski TF

Current protocols in microbiology Appendix 3:3B, 2006 Jan - Who cited this? | PubMed ID: 18770568 | Fulltext

Cutting edge: cytotoxic granule polarization and cytolysis can occur without central supramolecular activation cluster formation in CD8+ effector T cells.

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O'Keefe JP and Gajewski TF

Journal of immunology (Baltimore, Md. : 1950) 175(9):5581-5, 2005 Nov 1 - Who cited this? | PubMed ID: 16237042 | Fulltext

Phase II trial of the O6-alkylguanine DNA alkyltransferase inhibitor O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea in advanced melanoma.

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Gajewski TF, Sosman J, Gerson SL, Liu L, Dolan E, Lin S, and Vokes EE

Clinical cancer research : an official journal of the American Association for Cancer Research 11(21):7861-5, 2005 Nov 1 - Who cited this? | PubMed ID: 16278409 | Fulltext

CCI-779 in metastatic melanoma: a phase II trial of the California Cancer Consortium.

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Margolin K, Longmate J, Baratta T, Synold T, Christensen S, Weber J, Gajewski T, Quirt I, and Doroshow JH

Cancer 104(5):1045-8, 2005 Sep 1 - Who cited this? | PubMed ID: 16007689 | Fulltext

Glucose availability regulates IFN-gamma production and p70S6 kinase activation in CD8+ effector T cells.

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Cham CM and Gajewski TF

Journal of immunology (Baltimore, Md. : 1950) 174(8):4670-7, 2005 Apr 15 - Who cited this? | PubMed ID: 15814691 | Fulltext

Interaction of PD-L1 on tumor cells with PD-1 on tumor-specific T cells as a mechanism of immune evasion: implications for tumor immunotherapy.

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Blank C, Gajewski TF, and Mackensen A

Cancer immunology, immunotherapy : CII 54(4):307-14, 2005 Apr - Who cited this? | PubMed ID: 15599732 | Fulltext

ICAM-1 contributes to but is not essential for tumor antigen cross-priming and CD8+ T cell-mediated tumor rejection in vivo.

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Blank C, Brown I, Kacha AK, Markiewicz MA, and Gajewski TF

Journal of immunology (Baltimore, Md. : 1950) 174(6):3416-20, 2005 Mar 15 - Who cited this? | PubMed ID: 15749875 | Fulltext

Lymphoma-infiltrating immune cells.

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Gajewski TF

The New England journal of medicine 352(7):724-5; author reply 724-5, 2005 Feb 17 - Who cited this? | PubMed ID: 15719444 | Fulltext

Long-term follow-up of nonmyeloablative allogeneic stem cell transplantation for renal cell carcinoma: The University of Chicago Experience.

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Artz AS, Van Besien K, Zimmerman T, Gajewski TF, Rini BI, Hu HS, Stadler WM, and Vogelzang NJ

Bone marrow transplantation 35(3):253-60, 2005 Feb - Who cited this? | PubMed ID: 15543195 | Fulltext

Peripheral survival of naïve CD8+ T cells.

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Brown IE, Mashayekhi M, Markiewicz M, Alegre ML, and Gajewski TF

Apoptosis : an international journal on programmed cell death 10(1):5-11, 2005 Jan - Who cited this? | PubMed ID: 15711917 | Fulltext

Metabolic mechanisms of tumor resistance to T cell effector function.

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Cham CM and Gajewski TF

Immunologic research 31(2):107-18, 2005 - Who cited this? | PubMed ID: 15778509 | Fulltext

Dose-ranging pharmacodynamic study of tipifarnib (R115777) in patients with relapsed and refractory hematologic malignancies.

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Zimmerman TM, Harlin H, Odenike OM, Berk S, Sprague E, Karrison T, Stock W, Larson RA, Ratain MJ, and Gajewski TF

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 22(23):4816-22, 2004 Dec 1 - Who cited this? | PubMed ID: 15570084 | Fulltext

Overcoming immune resistance in the tumor microenvironment by blockade of indoleamine 2,3-dioxygenase and programmed death ligand 1.

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Gajewski TF

Current opinion in investigational drugs (London, England : 2000) 5(12):1279-83, 2004 Dec - Who cited this? | PubMed ID: 15648949 | Fulltext

Depletion of normal B cells with rituximab as an adjunct to IL-2 therapy for renal cell carcinoma and melanoma.

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Aklilu M, Stadler WM, Markiewicz M, Vogelzang NJ, Mahowald M, Johnson M, and Gajewski TF

Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 15(7):1109-14, 2004 Jul - Who cited this? | PubMed ID: 15205206 | Fulltext

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