Please enable Javascript

Labmeeting uses lots of Javascript - basically you can't use the site without it. So please enable Javascript in your browser. If your browser does not support Javascript, we recommend Firefox.

Papers authored by Gaestel M

Collect these papers and discover other ones on Labmeeting. Learn more.

Modulation of HSP27 alters hypoxia-induced endothelial permeability and related signaling pathways.

+ cite this

+ View Abstract

Liu T, Guevara OE, Warburton RR, Hill NS, Gaestel M, and Kayyali US

Journal of cellular physiology 220(3):600-10, 2009 Sep - Who cited this? | PubMed ID: 19373869 | Fulltext

MAPKAPK-2 modulates p38-MAPK localization and small heat shock protein phosphorylation but does not mediate the injury associated with p38-MAPK activation during myocardial ischemia.

+ cite this

+ View Abstract

Gorog DA, Jabr RI, Tanno M, Sarafraz N, Clark JE, Fisher SG, Cao XB, Bellahcene M, Dighe K, Kabir AM, Quinlan RA, Kato K, Gaestel M, Marber MS, and Heads RJ

Cell stress & chaperones 14(5):477-89, 2009 Sep - Who cited this? | PubMed ID: 19214782 | Fulltext

The p38 MAPK pathway inhibits tristetraprolin-directed decay of interleukin-10 and pro-inflammatory mediator mRNAs in murine macrophages.

+ cite this

+ View Abstract

Tudor C, Marchese FP, Hitti E, Aubareda A, Rawlinson L, Gaestel M, Blackshear PJ, Clark AR, Saklatvala J, and Dean JL

FEBS letters 583(12):1933-8, 2009 Jun 18 - Who cited this? | PubMed ID: 19416727 | Fulltext

MAPK-activated Protein Kinase 2 Differentially Regulates Plasmodium falciparum Glycosylphosphatidylinositol-induced Production of Tumor Necrosis Factor-{alpha} and Interleukin-12 in Macrophages.

+ cite this

+ View Abstract

Zhu J, Wu X, Goel S, Gowda NM, Kumar S, Krishnegowda G, Mishra G, Weinberg R, Li G, Gaestel M, Muta T, and Gowda DC

The Journal of biological chemistry 284(23):15750-61, 2009 Jun 5 - Who cited this? | PubMed ID: 19359247 | Fulltext

Targeting innate immunity protein kinase signalling in inflammation.

+ cite this

+ View Abstract

Gaestel M, Kotlyarov A, and Kracht M

Nature reviews. Drug discovery 8(6):480-99, 2009 Jun - Who cited this? | PubMed ID: 19483709 | Fulltext

MAPKAP kinase MK2 maintains self-renewal capacity of haematopoietic stem cells.

+ cite this

+ View Abstract

Schwermann J, Rathinam C, Schubert M, Schumacher S, Noyan F, Koseki H, Kotlyarov A, Klein C, and Gaestel M

The EMBO journal 28(10):1392-406, 2009 May 20 - Who cited this? | PubMed ID: 19369945 | Fulltext

RIG-I-mediated Activation of p38 MAPK Is Essential for Viral Induction of Interferon and Activation of Dendritic Cells: DEPENDENCE ON TRAF2 AND TAK1.

+ cite this

+ View Abstract

Mikkelsen SS, Jensen SB, Chiliveru S, Melchjorsen J, Julkunen I, Gaestel M, Arthur JS, Flavell RA, Ghosh S, and Paludan SR

The Journal of biological chemistry 284(16):10774-82, 2009 Apr 17 - Who cited this? | PubMed ID: 19224920 | Fulltext

Reduced oxazolone-induced skin inflammation in MAPKAP kinase 2 knockout mice.

+ cite this

+ View Abstract

Funding AT, Johansen C, Gaestel M, Bibby BM, Lilleholt LL, Kragballe K, and Iversen L

The Journal of investigative dermatology 129(4):891-8, 2009 Apr - Who cited this? | PubMed ID: 18987672 | Fulltext

Mutually exclusive STAT1 modifications identified by Ubc9/substrate dimerization-dependent SUMOylation.

+ cite this

+ View Abstract

Zimnik S, Gaestel M, and Niedenthal R

Nucleic acids research 37(4):e30, 2009 Mar - Who cited this? | PubMed ID: 19174562 | Fulltext

NAMPT is essential for the G-CSF-induced myeloid differentiation via a NAD(+)-sirtuin-1-dependent pathway.

+ cite this

+ View Abstract

Skokowa J, Lan D, Thakur BK, Wang F, Gupta K, Cario G, Brechlin AM, Schambach A, Hinrichsen L, Meyer G, Gaestel M, Stanulla M, Tong Q, and Welte K

Nature medicine 15(2):151-8, 2009 Feb - Who cited this? | PubMed ID: 19182797 | Fulltext

Mitogen activated protein kinase activated protein kinase 2 regulates actin polymerization and vascular leak in ventilator associated lung injury.

+ cite this

+ View Abstract

Damarla M, Hasan E, Boueiz A, Le A, Pae HH, Montouchet C, Kolb T, Simms T, Myers A, Kayyali US, Gaestel M, Peng X, Reddy SP, Damico R, and Hassoun PM

PLoS ONE 4(2):e4600, 2009 - Who cited this? | PubMed ID: 19240800 | Fulltext

Peptides as Signaling Inhibitors for Mammalian MAP Kinase Cascades.

+ cite this

+ View Abstract

Gaestel M and Kracht M

Current pharmaceutical design 15(20):2471-80, 2009 - Who cited this? | PubMed ID: 19601844 | Fulltext

MAP-kinase-activated protein kinase 2 expression and activity is induced after neuronal depolarization.

+ cite this

+ View Abstract

Thomas T, Hitti E, Kotlyarov A, Potschka H, and Gaestel M

The European journal of neuroscience 28(4):642-54, 2008 Aug - Who cited this? | PubMed ID: 18702688 | Fulltext

Deletion of MK2 signalling in vivo inhibits small Hsp phosphorylation but not diabetic nephropathy.

+ cite this

+ View Abstract

Park JK, Ronkina N, Höft A, Prohl C, Menne J, Gaestel M, Haller H, and Meier M

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 23(6):1844-53, 2008 Jun - Who cited this? | PubMed ID: 18182404 | Fulltext

Adenosine increases calcium sensitivity via receptor-independent activation of the p38/MK2 pathway in mesenteric arteries.

+ cite this

+ View Abstract

Martinka P, Lai EY, Fähling M, Jankowski V, Jankowski J, Schubert R, Gaestel M, Persson AE, Persson PB, and Patzak A

Acta physiologica (Oxford, England) 193(1):37-46, 2008 May - Who cited this? | PubMed ID: 18005245 | Fulltext

MAPKAP kinase 2-deficiency prevents neurons from cell death by reducing neuroinflammation - relevance in a mouse model of Parkinson's disease.

+ cite this

+ View Abstract

Thomas T, Timmer M, Cesnulevicius K, Hitti E, Kotlyarov A, and Gaestel M

Journal of neurochemistry 105(5):2039-52, 2008 May - Who cited this? | PubMed ID: 18298661 | Fulltext

Roles for TAB1 in regulating the IL-1-dependent phosphorylation of the TAB3 regulatory subunit and activity of the TAK1 complex.

+ cite this

+ View Abstract

Mendoza H, Campbell DG, Burness K, Hastie J, Ronkina N, Shim JH, Arthur JS, Davis RJ, Gaestel M, Johnson GL, Ghosh S, and Cohen P

The Biochemical journal 409(3):711-22, 2008 Feb 1 - Who cited this? | PubMed ID: 18021073 | Fulltext

MK2 and MK3--a pair of isoenzymes?.

+ cite this

+ View Abstract

Ronkina N, Kotlyarov A, and Gaestel M

Frontiers in bioscience : a journal and virtual library 13:5511, 2008 - Who cited this? | PubMed ID: 18508601 | Fulltext

Corrigendum: The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways.

+ cite this

Zaru R, Ronkina N, Gaestel M, Arthur JS, and Watts C

Nature immunology 9(1):105, 2008 Jan - Who cited this? | PubMed ID: 18087255 | Fulltext

Specificity of signaling from MAPKs to MAPKAPKs: Kinases' Tango Nuevo.

+ cite this

+ View Abstract

Gaestel M

Frontiers in bioscience : a journal and virtual library 13:6050-9, 2008 - Who cited this? | PubMed ID: 18508642 | Fulltext

Systemic deficiency of the MAP kinase-activated protein kinase 2 reduces atherosclerosis in hypercholesterolemic mice.

+ cite this

+ View Abstract

Jagavelu K, Tietge UJ, Gaestel M, Drexler H, Schieffer B, and Bavendiek U

Circulation research 101(11):1104-12, 2007 Nov 26 - Who cited this? | PubMed ID: 17885219 | Fulltext

The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways.

+ cite this

+ View Abstract

Zaru R, Ronkina N, Gaestel M, Arthur JS, and Watts C

Nature immunology 8(11):1227, 2007 Nov - Who cited this? | PubMed ID: 17906627 | Fulltext

Lack of MK2 inhibits myofibroblast formation and exacerbates pulmonary fibrosis.

+ cite this

+ View Abstract

Liu T, Warburton RR, Guevara OE, Hill NS, Fanburg BL, Gaestel M, and Kayyali US

American journal of respiratory cell and molecular biology 37(5):507-17, 2007 Nov - Who cited this? | PubMed ID: 17600313 | Fulltext

MK2 controls the level of negative feedback in the NF-kappaB pathway and is essential for vascular permeability and airway inflammation.

+ cite this

+ View Abstract

Gorska MM, Liang Q, Stafford SJ, Goplen N, Dharajiya N, Guo L, Sur S, Gaestel M, and Alam R

The Journal of experimental medicine 204(7):1637, 2007 Jul 9 - Who cited this? | PubMed ID: 17576778 | Fulltext

Distinct role of MAPKAPK-2 in the regulation of TNF gene expression by Toll-like receptor 7 and 9 ligands.

+ cite this

+ View Abstract

Thuraisingam T, Xu YZ, Moisan J, Lachance C, Garnon J, Di Marco S, Gaestel M, and Radzioch D

Molecular immunology 44(14):3482-91, 2007 Jul - Who cited this? | PubMed ID: 17485113 | Fulltext

MAPKAPK2-mediated LSP1 phosphorylation and FMLP-induced neutrophil polarization.

+ cite this

+ View Abstract

Wu Y, Zhan L, Ai Y, Hannigan M, Gaestel M, Huang CK, and Madri JA

Biochemical and biophysical research communications 358(1):170-5, 2007 Jun 22 - Who cited this? | PubMed ID: 17481585 | Fulltext

Ischemic preconditioning involves dual cardio-protective axes with p38MAPK as upstream target.

+ cite this

+ View Abstract

Nagy N, Shiroto K, Malik G, Huang CK, Gaestel M, Abdellatif M, Tosaki A, Maulik N, and Das DK

Journal of molecular and cellular cardiology 42(5):981-90, 2007 May - Who cited this? | PubMed ID: 17397860 | Fulltext

Smooth muscle alpha-actin expression and myofibroblast differentiation by TGFbeta are dependent upon MK2.

+ cite this

+ View Abstract

Sousa AM, Liu T, Guevara O, Stevens J, Fanburg BL, Gaestel M, Toksoz D, and Kayyali US

Journal of cellular biochemistry 100(6):1581-92, 2007 Apr 15 - Who cited this? | PubMed ID: 17163490 | Fulltext

Regulation of suppressor of cytokine signaling 3 (SOCS3) mRNA stability by TNF-alpha involves activation of the MKK6/p38MAPK/MK2 cascade.

+ cite this

+ View Abstract

Ehlting C, Lai WS, Schaper F, Brenndörfer ED, Matthes RJ, Heinrich PC, Ludwig S, Blackshear PJ, Gaestel M, Häussinger D, and Bode JG

Journal of immunology (Baltimore, Md. : 1950) 178(5):2813-26, 2007 Mar 1 - Who cited this? | PubMed ID: 17312125 | Fulltext

Ubc9 fusion-directed SUMOylation (UFDS): a method to analyze function of protein SUMOylation.

+ cite this

+ View Abstract

Jakobs A, Koehnke J, Himstedt F, Funk M, Korn B, Gaestel M, and Niedenthal R

Nature methods 4(3):245-50, 2007 Mar - Who cited this? | PubMed ID: 17277783 | Fulltext

The mitogen-activated protein kinase (MAPK)-activated protein kinases MK2 and MK3 cooperate in stimulation of tumor necrosis factor biosynthesis and stabilization of p38 MAPK.

+ cite this

+ View Abstract

Ronkina N, Kotlyarov A, Dittrich-Breiholz O, Kracht M, Hitti E, Milarski K, Askew R, Marusic S, Lin LL, Gaestel M, and Telliez JB

Molecular and cellular biology 27(1):170-81, 2007 Jan - Who cited this? | PubMed ID: 17030606 | Fulltext

Ubc9 fusion-directed SUMOylation identifies constitutive and inducible SUMOylation.

+ cite this

+ View Abstract

Jakobs A, Himstedt F, Funk M, Korn B, Gaestel M, and Niedenthal R

Nucleic acids research 35(17):e109, 2007 - Who cited this? | PubMed ID: 17709345 | Fulltext

Protein kinases as small molecule inhibitor targets in inflammation.

+ cite this

+ View Abstract

Gaestel M, Mengel A, Bothe U, and Asadullah K

Current medicinal chemistry 14(21):2214-34, 2007 - Who cited this? | PubMed ID: 17896971 | Fulltext

Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5.

+ cite this

+ View Abstract

Kant S, Schumacher S, Singh MK, Kispert A, Kotlyarov A, and Gaestel M

The Journal of biological chemistry 281(46):35511-9, 2006 Nov 17 - Who cited this? | PubMed ID: 16973613 | Fulltext

CXCL12 and C5a trigger cell migration via a PAK1/2-p38alpha MAPK-MAPKAP-K2-HSP27 pathway.

+ cite this

+ View Abstract

Rousseau S, Dolado I, Beardmore V, Shpiro N, Marquez R, Nebreda AR, Arthur JS, Case LM, Tessier-Lavigne M, Gaestel M, Cuenda A, and Cohen P

Cellular signalling 18(11):1897-905, 2006 Nov - Who cited this? | PubMed ID: 16574378 | Fulltext

Analysis of properties of small heat shock protein Hsp25 in MAPK-activated protein kinase 2 (MK2)-deficient cells: MK2-dependent insolubilization of Hsp25 oligomers correlates with susceptibility to stress.

+ cite this

+ View Abstract

Vertii A, Hakim C, Kotlyarov A, and Gaestel M

The Journal of biological chemistry 281(37):26966-75, 2006 Sep 15 - Who cited this? | PubMed ID: 16840785 | Fulltext

MAPK-activated protein kinase 2 deficiency in microglia inhibits pro-inflammatory mediator release and resultant neurotoxicity. Relevance to neuroinflammation in a transgenic mouse model of Alzheimer disease.

+ cite this

+ View Abstract

Culbert AA, Skaper SD, Howlett DR, Evans NA, Facci L, Soden PE, Seymour ZM, Guillot F, Gaestel M, and Richardson JC

The Journal of biological chemistry 281(33):23658-67, 2006 Aug 18 - Who cited this? | PubMed ID: 16774924 | Fulltext

MAPKAP kinase 2-deficient mice are resistant to collagen-induced arthritis.

+ cite this

+ View Abstract

Hegen M, Gaestel M, Nickerson-Nutter CL, Lin LL, and Telliez JB

Journal of immunology (Baltimore, Md. : 1950) 177(3):1913-7, 2006 Aug 1 - Who cited this? | PubMed ID: 16849504 | Fulltext

Activation of p38 mitogen-activated protein kinase contributes to the early cardiodepressant action of tumor necrosis factor.

+ cite this

+ View Abstract

Bellahcene M, Jacquet S, Cao XB, Tanno M, Haworth RS, Layland J, Kabir AM, Gaestel M, Davis RJ, Flavell RA, Shah AM, Avkiran M, and Marber MS

Journal of the American College of Cardiology 48(3):545-55, 2006 Aug 1 - Who cited this? | PubMed ID: 16875982 | Fulltext

Gene deletion of MK2 inhibits TNF-alpha and IL-6 and protects against cerulein-induced pancreatitis.

+ cite this

+ View Abstract

Tietz AB, Malo A, Diebold J, Kotlyarov A, Herbst A, Kolligs FT, Brandt-Nedelev B, Halangk W, Gaestel M, Göke B, and Schäfer C

American journal of physiology. Gastrointestinal and liver physiology 290(6), 2006 Jun - Who cited this? | PubMed ID: 16423921 | Fulltext

TLR7 ligand prevents allergen-induced airway hyperresponsiveness and eosinophilia in allergic asthma by a MYD88-dependent and MK2-independent pathway.

+ cite this

+ View Abstract

Moisan J, Camateros P, Thuraisingam T, Marion D, Koohsari H, Martin P, Boghdady ML, Ding A, Gaestel M, Guiot MC, Martin JG, and Radzioch D

American journal of physiology. Lung cellular and molecular physiology 290(5), 2006 May - Who cited this? | PubMed ID: 16361354 | Fulltext

Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element.

+ cite this

+ View Abstract

Hitti E, Iakovleva T, Brook M, Deppenmeier S, Gruber AD, Radzioch D, Clark AR, Blackshear PJ, Kotlyarov A, and Gaestel M

Molecular and cellular biology 26(6):2399-407, 2006 Mar - Who cited this? | PubMed ID: 16508014 | Fulltext

MAPKAP kinases - MKs - two's company, three's a crowd.

+ cite this

+ View Abstract

Gaestel M

Nature reviews. Molecular cell biology 7(2):120-30, 2006 Feb - Who cited this? | PubMed ID: 16421520 | Fulltext

Phosphorylation of HSF1 by MAPK-activated protein kinase 2 on serine 121, inhibits transcriptional activity and promotes HSP90 binding.

+ cite this

+ View Abstract

Wang X, Khaleque MA, Zhao MJ, Zhong R, Gaestel M, and Calderwood SK

The Journal of biological chemistry 281(2):782-91, 2006 Jan 13 - Who cited this? | PubMed ID: 16278218 | Fulltext

Molecular chaperones in signal transduction.

+ cite this

+ View Abstract

Gaestel M

Handbook of experimental pharmacology(172):93-109, 2006 - Who cited this? | PubMed ID: 16610356 | Fulltext

Hypoxia alters biophysical properties of endothelial cells via p38 MAPK- and Rho kinase-dependent pathways.

+ cite this

+ View Abstract

An SS, Pennella CM, Gonnabathula A, Chen J, Wang N, Gaestel M, Hassoun PM, Fredberg JJ, and Kayyali US

American journal of physiology. Cell physiology 289(3), 2005 Sep - Who cited this? | PubMed ID: 15857906 | Fulltext

Activation of mitogen-activated protein kinase kinase (MKK) 3 and MKK6 by type I interferons.

+ cite this

+ View Abstract

Li Y, Batra S, Sassano A, Majchrzak B, Levy DE, Gaestel M, Fish EN, Davis RJ, and Platanias LC

The Journal of biological chemistry 280(11):10001-10, 2005 Mar 18 - Who cited this? | PubMed ID: 15644321 | Fulltext

HDM2 phosphorylation by MAPKAP kinase 2.

+ cite this

+ View Abstract

Weber HO, Ludwig RL, Morrison D, Kotlyarov A, Gaestel M, and Vousden KH

Oncogene 24(12):1965-72, 2005 Mar 17 - Who cited this? | PubMed ID: 15688025 | Fulltext

Scaffolding by ERK3 regulates MK5 in development.

+ cite this

+ View Abstract

Schumacher S, Laass K, Kant S, Shi Y, Visel A, Gruber AD, Kotlyarov A, and Gaestel M

The EMBO journal 23(24):4770-9, 2004 Dec 8 - Who cited this? | PubMed ID: 15538386 | Fulltext

Role of heat shock protein 27 in cytoskeletal remodeling of the airway smooth muscle cell.

+ cite this

+ View Abstract

An SS, Fabry B, Mellema M, Bursac P, Gerthoffer WT, Kayyali US, Gaestel M, Shore SA, and Fredberg JJ

Journal of applied physiology (Bethesda, Md. : 1985) 96(5):1701-13, 2004 May - Who cited this? | PubMed ID: 14729728 | Fulltext

Search Google Scholar for Gaestel M

Join Labmeeting

Organize and search your PDF collection
Collect papers
Search millions of papers
Keep up to date with paper alerts
Read your papers from anywhere
Recommend papers to colleagues
Manage your lab

Labmeeting is a web service for researchers. Sign up with your academic email address.

Individuals or corporations not affiliated with an academic institution can request a trial subscription.

Got a question?
The Labmeeting Network
has the answer.
Ask scientists at top universities like Harvard, Stanford, and MIT for their expert opinion!