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Papers authored by Frye RF

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Inhibition of Intestinal and Hepatic Glucuronidation of Mycophenolic Acid by Ginkgo biloba Extract and Flavonoids.

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Mohamed ME and Frye RF

Drug metabolism and disposition: the biological fate of chemicals 38(2):270-5, 2010 Feb - Who cited this? | PubMed ID: 19889883 | Fulltext

Validation and application of a liquid chromatography-tandem mass spectrometric method for quantification of the drug transport probe fexofenadine in human plasma using 96-well filter plates.

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Stanton ML, Joy MS, and Frye RF

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 878(3-4):497-501, 2010 Feb 1 - Who cited this? | PubMed ID: 20045385 | Fulltext

ESRD impairs nonrenal clearance of fexofenadine but not midazolam.

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Nolin TD, Frye RF, Le P, Sadr H, Naud J, Leblond FA, Pichette V, and Himmelfarb J

Journal of the American Society of Nephrology : JASN 20(10):2269-76, 2009 Oct - Who cited this? | PubMed ID: 19696225 | Fulltext

Pharmacokinetics and tissue distribution of dodeca-2E,4E,8E,10E/Z-tetraenoic acid isobutylamides after oral administration in rats.

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Woelkart K, Frye RF, Derendorf H, Bauer R, and Butterweck V

Planta medica 75(12):1306-13, 2009 Oct - Who cited this? | PubMed ID: 19399718 | Fulltext

Early atorvastatin reduces hemorrhage after acute cerebral ischemia in diabetic rats.

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Elewa HF, Kozak A, El-Remessy AB, Frye RF, Johnson MH, Ergul A, and Fagan SC

The Journal of pharmacology and experimental therapeutics 330(2):532-40, 2009 Aug - Who cited this? | PubMed ID: 19478137 | Fulltext

A sensitive and specific liquid chromatography-tandem mass spectrometry method for the determination of intracellular and extracellular uric acid.

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Kim KM, Henderson GN, Ouyang X, Frye RF, Sautin YY, Feig DI, and Johnson RJ

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 877(22):2032-8, 2009 Jul 15 - Who cited this? | PubMed ID: 19520625 | Fulltext

Determination of visnagin in rat plasma by liquid chromatography with tandem mass spectrometry and its application to in vivo pharmacokinetic studies.

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Vanachayangkul P, Butterweck V, and Frye RF

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 877(7):653-6, 2009 Mar 1 - Who cited this? | PubMed ID: 19188097 | Fulltext

Simultaneous determination of uric acid metabolites allantoin, 6-aminouracil, and triuret in human urine using liquid chromatography-mass spectrometry.

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Kim KM, Henderson GN, Frye RF, Galloway CD, Brown NJ, Segal MS, Imaram W, Angerhofer A, and Johnson RJ

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 877(1-2):65-70, 2009 Jan 1 - Who cited this? | PubMed ID: 19081307 | Fulltext

Interpopulation Variation Frequency of Human Inosine 5'-Monophosphate Dehydrogenase Type II (IMPDH2) Genetic Polymorphisms.

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Mohamed ME, Frye RF, and Langaee TY

Genetic testing 12(4):513-6, 2008 Dec - Who cited this? | PubMed ID: 18976158 | Fulltext

Effect of the acute phase response induced by endotoxin administration on the expression and activity of UGT isoforms in rats.

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Alkharfy KM, Poloyac SM, Congiu M, Desmond PV, and Frye RF

Drug metabolism letters 2(4):248-55, 2008 Dec - Who cited this? | PubMed ID: 19356101 | Fulltext

Simplified method for determination of clarithromycin in human plasma using protein precipitation in a 96-well format and liquid chromatography-tandem mass spectrometry.

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Shin J, Pauly DF, Johnson JA, and Frye RF

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 871(1):130, 2008 Aug 1 - Who cited this? | PubMed ID: 18639501 | Fulltext

Determination of mycophenolic acid glucuronide in microsomal incubations using high performance liquid chromatography-tandem mass spectrometry.

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Mohamed ME, Harvey SS, and Frye RF

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 870(2):251-4, 2008 Jul 15 - Who cited this? | PubMed ID: 18602350 | Fulltext

A summer research training program to foster PharmD students' interest in research.

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Johnson JA, Moore MJ, Shin J, and Frye RF

American journal of pharmaceutical education 72(2):23, 2008 Apr 15 - Who cited this? | PubMed ID: 18483591 | Fulltext

Determination of N-desethylamodiaquine by hydrophilic interaction liquid chromatography with tandem mass spectrometry: Application to in vitro drug metabolism studies.

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Dravid PV and Frye RF

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 863(1):129-34, 2008 Feb 15 - Who cited this? | PubMed ID: 18255358 | Fulltext

Evaluation of flurbiprofen urinary ratios as in vivo indices for CYP2C9 activity.

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Zgheib NK, Frye RF, Tracy TS, Romkes M, and Branch RA

British journal of clinical pharmacology 63(4):477-87, 2007 Apr - Who cited this? | PubMed ID: 17054666 | Fulltext

Effect of valerian, valerian/hops extracts, and valerenic acid on glucuronidation in vitro.

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Alkharfy KM and Frye RF

Xenobiotica; the fate of foreign compounds in biological systems 37(2):113-23, 2007 Feb - Who cited this? | PubMed ID: 17484515 | Fulltext

Vancomycin disposition following intraperitoneal administration in children receiving peritoneal dialysis.

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Blowey DL, Warady BA, Abdel-Rahman S, Frye RF, and Manley HJ

Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 27(1):79-85, 2007 - Who cited this? | PubMed ID: 17179516 | Fulltext

Effect of conjugated equine estrogens on oxidative metabolism in middle-aged and elderly postmenopausal women.

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O'Connell MB, Frye RF, Matzke GR, St Peter JV, Willhite LA, Welch MR, Kowal P, and LaValleur J

Journal of clinical pharmacology 46(11):1299-307, 2006 Nov - Who cited this? | PubMed ID: 17050794 | Fulltext

Liver disease selectively modulates cytochrome P450--mediated metabolism.

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Frye RF, Zgheib NK, Matzke GR, Chaves-Gnecco D, Rabinovitz M, Shaikh OS, and Branch RA

Clinical pharmacology and therapeutics 80(3):235-45, 2006 Sep - Who cited this? | PubMed ID: 16952490 | Fulltext

Validation of incorporating flurbiprofen into the Pittsburgh cocktail.

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Zgheib NK, Frye RF, Tracy TS, Romkes M, and Branch RA

Clinical pharmacology and therapeutics 80(3):257-63, 2006 Sep - Who cited this? | PubMed ID: 16952492 | Fulltext

Cytochrome P450 mRNA expression in peripheral blood lymphocytes as a predictor of enzyme induction.

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Haas CE, Brazeau D, Cloen D, Booker BM, Frerichs V, Zaranek C, Frye RF, and Kufel T

European journal of clinical pharmacology 61(8):583-93, 2005 Sep - Who cited this? | PubMed ID: 16041547 | Fulltext

Pharmacokinetics of intraperitoneal cefazolin and ceftazidime coadministered to CAPD patients.

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Elwell RJ, Manley HJ, Frye RF, and Bailie GR

The International journal of artificial organs 28(8):808-16, 2005 Aug - Who cited this? | PubMed ID: 16211531 | Fulltext

Effect of age and postoperative time on cytochrome p450 enzyme activity following liver transplantation.

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Liu S, Frye RF, Branch RA, Venkataramanan R, Fung JJ, and Burckart GJ

Journal of clinical pharmacology 45(6):666-73, 2005 Jun - Who cited this? | PubMed ID: 15901748 | Fulltext

Cytochrome P-450 activity is differentially altered in severely injured patients.

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Harbrecht BG, Frye RF, Zenati MS, Branch RA, and Peitzman AB

Critical care medicine 33(3):541-6, 2005 Mar - Who cited this? | PubMed ID: 15753745 | Fulltext

The effect of trimethoprim on CYP2C8 mediated rosiglitazone metabolism in human liver microsomes and healthy subjects.

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Hruska MW, Amico JA, Langaee TY, Ferrell RE, Fitzgerald SM, and Frye RF

British journal of clinical pharmacology 59(1):70-9, 2005 Jan - Who cited this? | PubMed ID: 15606443 | Fulltext

Pharmacokinetics of intraperitoneal cefepime in automated peritoneal dialysis.

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Elwell RJ, Frye RF, and Bailie GR

Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 25(4):380-6, 2005 - Who cited this? | PubMed ID: 16022096 | Fulltext

Stability of cefepime in icodextrin peritoneal dialysis solution.

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Elwell RJ, Volino LR, and Frye RF

The Annals of pharmacotherapy 38(12):2041-4, 2004 Dec - Who cited this? | PubMed ID: 15494381 | Fulltext

Pyrosequencing method for genotyping cytochrome P450 CYP2C8 and CYP2C9 enzymes.

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Hruska MW, Frye RF, and Langaee TY

Clinical chemistry 50(12):2392-5, 2004 Dec - Who cited this? | PubMed ID: 15563491 | Fulltext

Bioequivalence revisited: influence of age and sex on CYP enzymes.

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Bebia Z, Buch SC, Wilson JW, Frye RF, Romkes M, Cecchetti A, Chaves-Gnecco D, and Branch RA

Clinical pharmacology and therapeutics 76(6):618-27, 2004 Dec - Who cited this? | PubMed ID: 15592333 | Fulltext

Effect of St John's wort on imatinib mesylate pharmacokinetics.

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Frye RF, Fitzgerald SM, Lagattuta TF, Hruska MW, and Egorin MJ

Clinical pharmacology and therapeutics 76(4):323-9, 2004 Oct - Who cited this? | PubMed ID: 15470331 | Fulltext

Determination of trimethoprim in low-volume human plasma by liquid chromatography.

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Hruska MW and Frye RF

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 807(2):301-5, 2004 Aug 5 - Who cited this? | PubMed ID: 15203044 | Fulltext

The effect of isoniazid on CYP2E1- and CYP4A-mediated hydroxylation of arachidonic acid in the rat liver and kidney.

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Poloyac SM, Tortorici MA, Przychodzin DI, Reynolds RB, Xie W, Frye RF, and Zemaitis MA

Drug metabolism and disposition: the biological fate of chemicals 32(7):727, 2004 Jul - Who cited this? | PubMed ID: 15205388 | Fulltext

Probing the world of cytochrome P450 enzymes.

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Frye RF

Molecular interventions 4(3):157-62, 2004 Jun - Who cited this? | PubMed ID: 15210869 | Fulltext

Simplified method for determination of rosiglitazone in human plasma.

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Hruska MW and Frye RF

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 803(2):317-20, 2004 Apr 25 - Who cited this? | PubMed ID: 15063342 | Fulltext

Impaired 6-hydroxychlorzoxazone elimination in patients with kidney disease: Implication for cytochrome P450 2E1 pharmacogenetic studies.

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Nolin TD, Gastonguay MR, Bies RR, Matzke GR, and Frye RF

Clinical pharmacology and therapeutics 74(6):555-68, 2003 Dec - Who cited this? | PubMed ID: 14663458 | Fulltext

Hepatic drug metabolism and transport in patients with kidney disease.

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Nolin TD, Frye RF, and Matzke GR

American journal of kidney diseases : the official journal of the National Kidney Foundation 42(5):906-25, 2003 Nov - Who cited this? | PubMed ID: 14582035 | Fulltext

Determination of 20-hydroxyeicosatetraenoic acid in microsomal incubates using high-performance liquid chromatography-mass spectrometry (HPLC-MS).

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Bolcato CA, Frye RF, Zemaitis MA, and Poloyac SM

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 794(2):363-72, 2003 Sep 5 - Who cited this? | PubMed ID: 12954388 | Fulltext

Cytochrome P450 mediated-drug metabolism is reduced in children with sepsis-induced multiple organ failure.

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Carcillo JA, Doughty L, Kofos D, Frye RF, Kaplan SS, Sasser H, and Burckart GJ

Intensive care medicine 29(6):980-4, 2003 Jun - Who cited this? | PubMed ID: 12698250 | Fulltext

Coordinated intrahepatic and extrahepatic regulation of cytochrome p4502D6 in healthy subjects and in patients after liver transplantation.

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Carcillo JA, Adedoyin A, Burckart GJ, Frye RF, Venkataramanan R, Knoll C, Thummel K, Roskos L, Wilson JW, Sereika S, Romkes M, Bebia Z, and Branch RA

Clinical pharmacology and therapeutics 73(5):456-67, 2003 May - Who cited this? | PubMed ID: 12732845 | Fulltext

Differences in flurbiprofen pharmacokinetics between CYP2C9*1/*1, *1/*2, and *1/*3 genotypes.

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Lee CR, Pieper JA, Frye RF, Hinderliter AL, Blaisdell JA, and Goldstein JA

European journal of clinical pharmacology 58(12):791-4, 2003 Apr - Who cited this? | PubMed ID: 12698304 | Fulltext

Effect of hepatic impairment on the pharmacokinetics of atomoxetine and its metabolites.

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Chalon SA, Desager JP, Desante KA, Frye RF, Witcher J, Long AJ, Sauer JM, Golnez JL, Smith BP, Thomasson HR, and Horsmans Y

Clinical pharmacology and therapeutics 73(3):178-91, 2003 Mar - Who cited this? | PubMed ID: 12621383 | Fulltext

Influence of DHEA administration on 24-hour cortisol concentrations.

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Kroboth PD, Amico JA, Stone RA, Folan M, Frye RF, Kroboth FJ, Bigos KL, Fabian TJ, Linares AM, Pollock BG, and Hakala C

Journal of clinical psychopharmacology 23(1):96-9, 2003 Feb - Who cited this? | PubMed ID: 12544381 | Fulltext

Stereoselective determination of the CYP2C19 probe drug mephenytoin in human urine by gas chromatography-mass spectrometry.

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Nolin TD and Frye RF

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 783(1):265-71, 2003 Jan 5 - Who cited this? | PubMed ID: 12450547 | Fulltext

Stability of atropine sulfate prepared for mass chemical terrorism.

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Dix J, Weber RJ, Frye RF, Nolin TD, Mrvos R, and Krenzelok E

Journal of toxicology. Clinical toxicology 41(6):771-5, 2003 - Who cited this? | PubMed ID: 14677786 | Fulltext

Tolbutamide, flurbiprofen, and losartan as probes of CYP2C9 activity in humans.

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Lee CR, Pieper JA, Frye RF, Hinderliter AL, Blaisdell JA, and Goldstein JA

Journal of clinical pharmacology 43(1):84-91, 2003 Jan - Who cited this? | PubMed ID: 12520632 | Fulltext

Application of semisimultaneous midazolam administration for hepatic and intestinal cytochrome P450 3A phenotyping.

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Lee JI, Chaves-Gnecco D, Amico JA, Kroboth PD, Wilson JW, and Frye RF

Clinical pharmacology and therapeutics 72(6):718-28, 2002 Dec - Who cited this? | PubMed ID: 12496753 | Fulltext

Effect of nortriptyline and paroxetine on CYP2D6 activity in depressed elderly patients.

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Solai LK, Pollock BG, Mulsant BH, Frye RF, Miller MD, Sweet RA, Kirshner M, Sorisio D, Begley A, and Reynolds CF

Journal of clinical psychopharmacology 22(5):481-6, 2002 Oct - Who cited this? | PubMed ID: 12352271 | Fulltext

Plasma levels of TNF-alpha and IL-6 are inversely related to cytochrome P450-dependent drug metabolism in patients with congestive heart failure.

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Frye RF, Schneider VM, Frye CS, and Feldman AM

Journal of cardiac failure 8(5):315-9, 2002 Oct - Who cited this? | PubMed ID: 12411982 | Fulltext

Differential effect of IFNalpha-2b on the cytochrome P450 enzyme system: a potential basis of IFN toxicity and its modulation by other drugs.

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Islam M, Frye RF, Richards TJ, Sbeitan I, Donnelly SS, Glue P, Agarwala SS, and Kirkwood JM

Clinical cancer research : an official journal of the American Association for Cancer Research 8(8):2480, 2002 Aug - Who cited this? | PubMed ID: 12171873 | Fulltext

Sensitive liquid chromatographic method using fluorescence detection for the determination of estradiol 3- and 17-glucuronides in rat and human liver microsomal incubations: formation kinetics.

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Alkharfy KM and Frye RF

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 774(1):33-8, 2002 Jul 5 - Who cited this? | PubMed ID: 12052720 | Fulltext

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