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Papers authored by Frydman J

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The predicted structure of the headpiece of the huntingtin protein and its implications on huntingtin aggregation.

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Kelley NW, Huang X, Tam S, Spiess C, Frydman J, and Pande VS

Journal of molecular biology 388(5):919-27, 2009 May 22 - Who cited this? | PubMed ID: 19361448 | Fulltext

Thyroid resection improves perception of swallowing function in patients with thyroid disease.

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Greenblatt DY, Sippel R, Leverson G, Frydman J, Schaefer S, and Chen H

World journal of surgery 33(2):255-60, 2009 Feb - Who cited this? | PubMed ID: 19034567 | Fulltext

The Hsp90 mosaic: a picture emerges.

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Mayer MP, Prodromou C, and Frydman J

Nature structural & molecular biology 16(1):2-6, 2009 Jan - Who cited this? | PubMed ID: 19125165 | Fulltext

Assessment of Effects of a Cordia salicifolia Extract on the Radiolabeling of Blood Constituents and on the Morphology of Red Blood Cells.

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Frydman JN, Rocha VC, Benarroz MO, Rocha GS, Pereira MO, de Souza da Fonseca A, and Bernardo-Filho M

Journal of medicinal food 11(4):767-72, 2008 Dec - Who cited this? | PubMed ID: 19053872 | Fulltext

Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly made proteins with complex topologies.

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Yam AY, Xia Y, Lin HT, Burlingame A, Gerstein M, and Frydman J

Nature structural & molecular biology, 2008 Nov 16 - Who cited this? | PubMed ID: 19011634 | Fulltext

Misfolded proteins partition between two distinct quality control compartments.

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Kaganovich D, Kopito R, and Frydman J

Nature 454(7208):1088, 2008 Aug 28 - Who cited this? | PubMed ID: 18756251 | Fulltext

Mechanism of lid closure in the eukaryotic chaperonin TRiC/CCT.

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Booth CR, Meyer AS, Cong Y, Topf M, Sali A, Ludtke SJ, Chiu W, and Frydman J

Nature structural & molecular biology, 2008 Jun 8 - Who cited this? | PubMed ID: 18536725 | Fulltext

Cinnamomum zeylanicum extract on the radiolabelling of blood constituents and the morphometry of red blood cells: in vitro assay.

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Benarroz MO, Fonseca AS, Rocha GS, Frydman JN, Rocha VC, Pereira MO, and Bernardo-Filho M

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 66(2):139, 2008 Feb - Who cited this? | PubMed ID: 17936634 | Fulltext

Diverse cellular functions of the Hsp90 molecular chaperone uncovered using systems approaches.

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McClellan AJ, Xia Y, Deutschbauer AM, Davis RW, Gerstein M, and Frydman J

Cell 131(1):121, 2007 Oct 5 - Who cited this? | PubMed ID: 17923092 | Fulltext

Acetylsalicylic acid decreases the labeling of blood constituents with technetium-99M.

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Fonseca AS, Frydman JN, Rocha VC, and Bernardo-Filho M

Acta biologica Hungarica 58(2):187, 2007 Jun - Who cited this? | PubMed ID: 17585508 | Fulltext

Essential function of the built-in lid in the allosteric regulation of eukaryotic and archaeal chaperonins.

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Reissmann S, Parnot C, Booth CR, Chiu W, and Frydman J

Nature structural & molecular biology 14(5):432, 2007 May - Who cited this? | PubMed ID: 17460696 | Fulltext

Reverse-alignment surgical skills assessment.

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Gould JC and Frydman J

Surgical endoscopy 21(4):669, 2007 Apr - Who cited this? | PubMed ID: 17285380 | Fulltext

Evolutionary constraints on chaperone-mediated folding provide an antiviral approach refractory to development of drug resistance.

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Geller R, Vignuzzi M, Andino R, and Frydman J

Genes & development 21(2):195, 2007 Jan 15 - Who cited this? | PubMed ID: 17234885 | Fulltext

Identification of the TRiC/CCT substrate binding sites uncovers the function of subunit diversity in eukaryotic chaperonins.

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Spiess C, Miller EJ, McClellan AJ, and Frydman J

Molecular cell 24(1):25, 2006 Oct 6 - Who cited this? | PubMed ID: 17018290 | Fulltext

The chaperonin TRiC controls polyglutamine aggregation and toxicity through subunit-specific interactions.

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Tam S, Geller R, Spiess C, and Frydman J

Nature cell biology 8(10):1155, 2006 Oct - Who cited this? | PubMed ID: 16980959 | Fulltext

Modeling of possible subunit arrangements in the eukaryotic chaperonin TRiC.

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Miller EJ, Meyer AS, and Frydman J

Protein science : a publication of the Protein Society 15(6):1522, 2006 Jun - Who cited this? | PubMed ID: 16672233 | Fulltext

Chaperonin GroEL and its mutant D87K protect from ischemia in vivo and in vitro.

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Xu L, Dayal M, Ouyang YB, Sun Y, Yang CF, Frydman J, and Giffard RG

Neurobiology of aging 27(4):562, 2006 Apr - Who cited this? | PubMed ID: 16257478 | Fulltext

Systems analyses reveal two chaperone networks with distinct functions in eukaryotic cells.

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Albanèse V, Yam AY, Baughman J, Parnot C, and Frydman J

Cell 124(1):75, 2006 Jan 13 - Who cited this? | PubMed ID: 16413483 | Fulltext

Probing the sequence of conformationally induced polarity changes in the molecular chaperonin GroEL with fluorescence spectroscopy.

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Kim SY, Semyonov AN, Twieg RJ, Horwich AL, Frydman J, and Moerner WE

The journal of physical chemistry. B 109(51):24517, 2005 Dec 29 - Who cited this? | PubMed ID: 16375456 | Fulltext

Hsp110 cooperates with different cytosolic HSP70 systems in a pathway for de novo folding.

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Yam AY, Albanèse V, Lin HT, and Frydman J

The Journal of biological chemistry 280(50):41252, 2005 Dec 16 - Who cited this? | PubMed ID: 16219770 | Fulltext

Protein quality control: chaperones culling corrupt conformations.

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McClellan AJ, Tam S, Kaganovich D, and Frydman J

Nature cell biology 7(8):736, 2005 Aug - Who cited this? | PubMed ID: 16056264 | Fulltext

The cotranslational contacts between ribosome-bound nascent polypeptides and the subunits of the hetero-oligomeric chaperonin TRiC probed by photocross-linking.

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Etchells SA, Meyer AS, Yam AY, Roobol A, Miao Y, Shao Y, Carden MJ, Skach WR, Frydman J, and Johnson AE

The Journal of biological chemistry 280(30):28118, 2005 Jul 29 - Who cited this? | PubMed ID: 15929940 | Fulltext

Folding and quality control of the VHL tumor suppressor proceed through distinct chaperone pathways.

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McClellan AJ, Scott MD, and Frydman J

Cell 121(5):739, 2005 Jun 3 - Who cited this? | PubMed ID: 15935760 | Fulltext

Actin mutations in hypertrophic and dilated cardiomyopathy cause inefficient protein folding and perturbed filament formation.

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Vang S, Corydon TJ, Børglum AD, Scott MD, Frydman J, Mogensen J, Gregersen N, and Bross P

The FEBS journal 272(8):2037, 2005 Apr - Who cited this? | PubMed ID: 15819894 | Fulltext

Influence of antipyretic drugs on the labeling of blood elements with technetium-99m.

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Fonseca AS, Frydman JN, Santos R, and Bernardo-Filho M

Acta biologica Hungarica 56(3-4):275, 2005 - Who cited this? | PubMed ID: 16196202 | Fulltext

Mechanism of the eukaryotic chaperonin: protein folding in the chamber of secrets.

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Spiess C, Meyer AS, Reissmann S, and Frydman J

Trends in cell biology 14(11):598, 2004 Nov - Who cited this? | PubMed ID: 15519848 | Fulltext

Thallium-pertechnetate subtraction scanning in the preoperative localization of an ectopic undescended parathyroid gland.

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Frydman J, Bianco J, Drezner M, and Chen H

Clinical nuclear medicine 29(9):542, 2004 Sep - Who cited this? | PubMed ID: 15311119 | Fulltext

Tumorigenic mutations in VHL disrupt folding in vivo by interfering with chaperonin binding.

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Feldman DE, Spiess C, Howard DE, and Frydman J

Molecular cell 12(5):1213, 2003 Nov - Who cited this? | PubMed ID: 14636579 | Fulltext

Closing the folding chamber of the eukaryotic chaperonin requires the transition state of ATP hydrolysis.

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Meyer AS, Gillespie JR, Walther D, Millet IS, Doniach S, and Frydman J

Cell 113(3):369, 2003 May 2 - Who cited this? | PubMed ID: 12732144 | Fulltext

The Hsp70 and TRiC/CCT chaperone systems cooperate in vivo to assemble the von Hippel-Lindau tumor suppressor complex.

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Melville MW, McClellan AJ, Meyer AS, Darveau A, and Frydman J

Molecular and cellular biology 23(9):3141, 2003 May - Who cited this? | PubMed ID: 12697815 | Fulltext

Aberrant protein folding as the molecular basis of cancer.

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Scott MD and Frydman J

Methods in molecular biology (Clifton, N.J.) 232:67, 2003 - Who cited this? | PubMed ID: 12840540 | Fulltext

Where chaperones and nascent polypeptides meet.

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Albanèse V and Frydman J

Nature structural biology 9(10):716, 2002 Oct - Who cited this? | PubMed ID: 12352951 | Fulltext

Review: cellular substrates of the eukaryotic chaperonin TRiC/CCT.

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Dunn AY, Melville MW, and Frydman J

Journal of structural biology 135(2):176, 2001 Aug - Who cited this? | PubMed ID: 11580267 | Fulltext

Molecular chaperones and the art of recognizing a lost cause.

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McClellan AJ and Frydman J

Nature cell biology 3(2):0, 2001 Feb - Who cited this? | PubMed ID: 11175763 | Fulltext

Folding of newly translated proteins in vivo: the role of molecular chaperones.

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Frydman J

Annual review of biochemistry 70:603, 2001 - Who cited this? | PubMed ID: 11395418 | Fulltext

The interaction of the chaperonin tailless complex polypeptide 1 (TCP1) ring complex (TRiC) with ribosome-bound nascent chains examined using photo-cross-linking.

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McCallum CD, Do H, Johnson AE, and Frydman J

The Journal of cell biology 149(3):591, 2000 May 1 - Who cited this? | PubMed ID: 10791973 | Fulltext

Protein folding in vivo: the importance of molecular chaperones.

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Feldman DE and Frydman J

Current opinion in structural biology 10(1):26, 2000 Feb - Who cited this? | PubMed ID: 10679467 | Fulltext

Folding assays. Assessing the native conformation of proteins.

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Thulasiraman V, Ferreyra RG, and Frydman J

Methods in molecular biology (Clifton, N.J.) 140:169, 2000 - Who cited this? | PubMed ID: 11484486 | Fulltext

Monitoring actin folding. Purification protocols for labeled proteins and binding to DNase I-sepharose beads.

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Thulasiraman V, Ferreyra RG, and Frydman J

Methods in molecular biology (Clifton, N.J.) 140:161, 2000 - Who cited this? | PubMed ID: 11484485 | Fulltext

Purification of the cytosolic chaperonin TRiC from bovine testis.

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Ferreyra RG and Frydman J

Methods in molecular biology (Clifton, N.J.) 140:153, 2000 - Who cited this? | PubMed ID: 11484484 | Fulltext

Formation of the VHL-elongin BC tumor suppressor complex is mediated by the chaperonin TRiC.

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Feldman DE, Thulasiraman V, Ferreyra RG, and Frydman J

Molecular cell 4(6):1051, 1999 Dec - Who cited this? | PubMed ID: 10635329 | Fulltext

Co-translational domain folding as the structural basis for the rapid de novo folding of firefly luciferase.

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Frydman J, Erdjument-Bromage H, Tempst P, and Hartl FU

Nature structural biology 6(7):697, 1999 Jul - Who cited this? | PubMed ID: 10404229 | Fulltext

In vivo newly translated polypeptides are sequestered in a protected folding environment.

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Thulasiraman V, Yang CF, and Frydman J

The EMBO journal 18(1):85, 1999 Jan 4 - Who cited this? | PubMed ID: 9878053 | Fulltext

Directionality of polypeptide transfer in the mitochondrial pathway of chaperone-mediated protein folding.

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Heyrovská N, Frydman J, Höhfeld J, and Hartl FU

Biological chemistry 379(3):301, 1998 Mar - Who cited this? | PubMed ID: 9563826 | Fulltext

Chaperones get in touch: the Hip-Hop connection.

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Frydman J and Höhfeld J

Trends in biochemical sciences 22(3):87, 1997 Mar - Who cited this? | PubMed ID: 9066258 | Fulltext

Principles of chaperone-assisted protein folding: differences between in vitro and in vivo mechanisms.

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Frydman J and Hartl FU

Science (New York, N.Y.) 272(5267):1497, 1996 Jun 7 - Who cited this? | PubMed ID: 8633246 | Fulltext

Tcp20, a subunit of the eukaryotic TRiC chaperonin from humans and yeast.

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Li WZ, Lin P, Frydman J, Boal TR, Cardillo TS, Richard LM, Toth D, Lichtman MA, Hartl FU, and Sherman F

The Journal of biological chemistry 269(28):18616, 1994 Jul 15 - Who cited this? | PubMed ID: 8034610 | Fulltext

Folding of nascent polypeptide chains in a high molecular mass assembly with molecular chaperones.

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Frydman J, Nimmesgern E, Ohtsuka K, and Hartl FU

Nature 370(6485):111, 1994 Jul 14 - Who cited this? | PubMed ID: 8022479 | Fulltext

Function in protein folding of TRiC, a cytosolic ring complex containing TCP-1 and structurally related subunits.

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Frydman J, Nimmesgern E, Erdjument-Bromage H, Wall JS, Tempst P, and Hartl FU

The EMBO journal 11(13):4767, 1992 Dec - Who cited this? | PubMed ID: 1361170 | Fulltext

An ATP-stabilized inhibitor of the proteasome is a component of the 1500-kDa ubiquitin conjugate-degrading complex.

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Driscoll J, Frydman J, and Goldberg AL

Proceedings of the National Academy of Sciences of the United States of America 89(11):4986, 1992 Jun 1 - Who cited this? | PubMed ID: 1317579 | Fulltext

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