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Papers authored by Fridman R

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Active site ring-opening of a thiirane moiety and picomolar inhibition of gelatinases.

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Forbes C, Shi Q, Fisher JF, Lee M, Hesek D, Llarrull LI, Toth M, Gossing M, Fridman R, and Mobashery S

Chemical biology & drug design 74(6):527-34, 2009 Dec - Who cited this? | PubMed ID: 19807733 | Fulltext

Synthesis, kinetic characterization and metabolism of diastereomeric 2-(1-(4-phenoxyphenylsulfonyl)ethyl)thiiranes as potent gelatinase and MT1-MMP inhibitors.

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Gooyit M, Lee M, Hesek D, Boggess B, Oliver AG, Fridman R, Mobashery S, and Chang M

Chemical biology & drug design 74(6):535-46, 2009 Dec - Who cited this? | PubMed ID: 19824893 | Fulltext

Unilateral versus bilateral first ray surgery: a prospective study of 186 consecutive cases-patient satisfaction, cost to society, and complications.

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Fridman R, Cain JD, Weil L, Weil LS, and Ray TB

Foot & ankle specialist 2(3):123-9, 2009 Jun - Who cited this? | PubMed ID: 19825763 | Fulltext

A potent gelatinase inhibitor with anti-tumor-invasive activity and its metabolic disposition.

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Lee M, Celenza G, Boggess B, Blase J, Shi Q, Toth M, Bernardo MM, Wolter WR, Suckow MA, Hesek D, Noll BC, Fridman R, Mobashery S, and Chang M

Chemical biology & drug design 73(2):189-202, 2009 Feb - Who cited this? | PubMed ID: 19207421 | Fulltext

Extracorporeal shockwave therapy for interdigital neuroma: a randomized, placebo-controlled, double-blind trial.

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Fridman R, Cain JD, and Weil L

Journal of the American Podiatric Medical Association 99(3):191-3, 2009 - Who cited this? | PubMed ID: 19448168 | Fulltext

Letters to the editor: extracorporeal shockwave therapy for interdigital neuroma: a randomized, placebo-controlled, double-blind trial.

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Fridman R and Weil L

Journal of the American Podiatric Medical Association 99(5):474, 2009 - Who cited this? | PubMed ID: 19767561 | Fulltext

Novel MMP-9 Substrates in Cancer Cells Revealed by a Label-free Quantitative Proteomics Approach.

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Xu D, Suenaga N, Edelmann MJ, Fridman R, Muschel RJ, and Kessler BM

Molecular & cellular proteomics : MCP 7(11):2215-28, 2008 Nov - Who cited this? | PubMed ID: 18596065 | Fulltext

Identification and role of the homodimerization interface of the GPI-anchored MMP25 (MT6-MMP).

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Zhao H, Sohail A, Sun Q, Shi Q, Kim S, Mobashery S, and Fridman R

The Journal of biological chemistry, 2008 Oct 20 - Who cited this? | PubMed ID: 18936094 | Fulltext

Are matrix metalloproteinases relevant therapeutic targets for prostate cancer bone metastasis?.

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Bonfil RD, Fridman R, Mobashery S, and Cher ML

Current oncology (Toronto, Ont.) 15(4):188-92, 2008 Aug - Who cited this? | PubMed ID: 18769612 | Fulltext

The inactive 44-kDa processed form of membrane type 1 matrix metalloproteinase (MT1-MMP) enhances proteolytic activity via regulation of endocytosis of active MT1-MMP.

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Cho JA, Osenkowski P, Zhao H, Kim S, Toth M, Cole K, Aboukameel A, Saliganan A, Schuger L, Bonfil RD, and Fridman R

The Journal of biological chemistry 283(25):17391, 2008 Jun 20 - Who cited this? | PubMed ID: 18413312 | Fulltext

MT4-(MMP17) and MT6-MMP (MMP25), A unique set of membrane-anchored matrix metalloproteinases: properties and expression in cancer.

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Sohail A, Sun Q, Zhao H, Bernardo MM, Cho JA, and Fridman R

Cancer metastasis reviews 27(2):289-302, 2008 Jun - Who cited this? | PubMed ID: 18286233 | Fulltext

Extracorporeal shockwave therapy for the treatment of achilles tendinopathies: a prospective study.

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Fridman R, Cain JD, Weil L, and Weil L

Journal of the American Podiatric Medical Association 98(6):466-8, 2008 - Who cited this? | PubMed ID: 19017855 | Fulltext

Galectin-3 cleavage: a novel surrogate marker for matrix metalloproteinase activity in growing breast cancers.

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Nangia-Makker P, Raz T, Tait L, Hogan V, Fridman R, and Raz A

Cancer research 67(24):11760, 2007 Dec 15 - Who cited this? | PubMed ID: 18089806 | Fulltext

Molecular structures and dynamics of the stepwise activation mechanism of a matrix metalloproteinase zymogen: challenging the cysteine switch dogma.

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Rosenblum G, Meroueh S, Toth M, Fisher JF, Fridman R, Mobashery S, and Sagi I

Journal of the American Chemical Society 129(44):13566, 2007 Nov 7 - Who cited this? | PubMed ID: 17929919 | Fulltext

Metabolism of a highly selective gelatinase inhibitor generates active metabolite.

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Lee M, Villegas-Estrada A, Celenza G, Boggess B, Toth M, Kreitinger G, Forbes C, Fridman R, Mobashery S, and Chang M

Chemical biology & drug design 70(5):371-82, 2007 Nov - Who cited this? | PubMed ID: 17927722 | Fulltext

Activation-coupled membrane-type 1 matrix metalloproteinase membrane trafficking.

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Wu YI, Munshi HG, Snipas SJ, Salvesen GS, Fridman R, and Stack MS

The Biochemical journal 407(2):171-7, 2007 Oct 15 - Who cited this? | PubMed ID: 17650075 | Fulltext

MMP25 (MT6-MMP) is highly expressed in human colon cancer, promotes tumor growth, and exhibits unique biochemical properties.

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Sun Q, Weber CR, Sohail A, Bernardo MM, Toth M, Zhao H, Turner JR, and Fridman R

The Journal of biological chemistry 282(30):21998-2010, 2007 Jul 27 - Who cited this? | PubMed ID: 17513868 | Fulltext

Prostate cancer-associated membrane type 1-matrix metalloproteinase: a pivotal role in bone response and intraosseous tumor growth.

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Bonfil RD, Dong Z, Trindade Filho JC, Sabbota A, Osenkowski P, Nabha S, Yamamoto H, Chinni SR, Zhao H, Mobashery S, Vessella RL, Fridman R, and Cher ML

The American journal of pathology 170(6):2100-11, 2007 Jun - Who cited this? | PubMed ID: 17525276 | Fulltext

SPARC upregulates MT1-MMP expression, MMP-2 activation, and the secretion and cleavage of galectin-3 in U87MG glioma cells.

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McClung HM, Thomas SL, Osenkowski P, Toth M, Menon P, Raz A, Fridman R, and Rempel SA

Neuroscience letters 419(2):172, 2007 May 29 - Who cited this? | PubMed ID: 17490812 | Fulltext

The type I collagen induction of MT1-MMP-mediated MMP-2 activation is repressed by alphaVbeta3 integrin in human breast cancer cells.

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Borrirukwanit K, Lafleur MA, Mercuri FA, Blick T, Price JT, Fridman R, Pereira JJ, Leardkamonkarn V, and Thompson EW

Matrix biology : journal of the International Society for Matrix Biology 26(4):291-305, 2007 May - Who cited this? | PubMed ID: 17175151 | Fulltext

Vaginal birth after cesarean: do California hospital policies follow national guidelines?.

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Shihady IR, Broussard P, Bolton LB, Fink A, Fridman M, Fridman R, Aydin C, Korst LM, and Gregory KD

The Journal of reproductive medicine 52(5):349-58, 2007 May - Who cited this? | PubMed ID: 17583231 | Fulltext

Functional expression of recombinant human stefin A in mammalian and bacterial cells.

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Calkins CC, Dosescu J, Day NA, Ren WP, Fridman R, Sloane BF, and Moin K

Protein expression and purification 52(2):463-71, 2007 Apr - Who cited this? | PubMed ID: 17208452 | Fulltext

Proteases, growth factors, chemokines, and the microenvironment in prostate cancer bone metastasis.

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Bonfil RD, Chinni S, Fridman R, Kim HR, and Cher ML

Urologic oncology 25(5):407-11, 2007 - Who cited this? | PubMed ID: 17826661 | Fulltext

MT1-MMP shedding involves an ADAM and is independent of its localization in lipid rafts.

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Toth M, Sohail A, Mobashery S, and Fridman R

Biochemical and biophysical research communications 350(2):377-84, 2006 Nov 17 - Who cited this? | PubMed ID: 17007816 | Fulltext

Identification of CD63 as a tissue inhibitor of metalloproteinase-1 interacting cell surface protein.

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Jung KK, Liu XW, Chirco R, Fridman R, and Kim HR

The EMBO journal 25(17):3934, 2006 Sep 6 - Who cited this? | PubMed ID: 16917503 | Fulltext

Synthesis of an inhibitor-tethered resin for detection of active matrix metalloproteinases involved in disease.

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Hesek D, Toth M, Krchnak V, Fridman R, and Mobashery S

The Journal of organic chemistry 71(16):5848-54, 2006 Aug 4 - Who cited this? | PubMed ID: 16872162 | Fulltext

Inhibition of human prostate cancer growth, osteolysis and angiogenesis in a bone metastasis model by a novel mechanism-based selective gelatinase inhibitor.

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Bonfil RD, Sabbota A, Nabha S, Bernardo MM, Dong Z, Meng H, Yamamoto H, Chinni SR, Lim IT, Chang M, Filetti LC, Mobashery S, Cher ML, and Fridman R

International journal of cancer. Journal international du cancer 118(11):2721-6, 2006 Jun 1 - Who cited this? | PubMed ID: 16381009 | Fulltext

TIMP-1 regulation of cell cycle in human breast epithelial cells via stabilization of p27(KIP1) protein.

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Taube ME, Liu XW, Fridman R, and Kim HR

Oncogene 25(21):3041-8, 2006 May 18 - Who cited this? | PubMed ID: 16407831 | Fulltext

Design and characterization of a metalloproteinase inhibitor-tethered resin for the detection of active MMPs in biological samples.

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Hesek D, Toth M, Meroueh SO, Brown S, Zhao H, Sakr W, Fridman R, and Mobashery S

Chemistry & biology 13(4):379-86, 2006 Apr - Who cited this? | PubMed ID: 16632250 | Fulltext

Tumor epithelial cell matrix metalloproteinase 9 is a target for antimetastatic therapy in colorectal cancer.

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Lubbe WJ, Zhou ZY, Fu W, Zuzga D, Schulz S, Fridman R, Muschel RJ, Waldman SA, and Pitari GM

Clinical cancer research : an official journal of the American Association for Cancer Research 12(6):1876-82, 2006 Mar 15 - Who cited this? | PubMed ID: 16551873 | Fulltext

Potent mechanism-based inhibitors for matrix metalloproteinases.

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Ikejiri M, Bernardo MM, Bonfil RD, Toth M, Chang M, Fridman R, and Mobashery S

The Journal of biological chemistry 280(40):33992-4002, 2005 Oct 7 - Who cited this? | PubMed ID: 16046398 | Fulltext

Synthesis of chiral 2-(4-phenoxyphenylsulfonylmethyl)thiiranes as selective gelatinase inhibitors.

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Lee M, Bernardo MM, Meroueh SO, Brown S, Fridman R, and Mobashery S

Organic letters 7(20):4463-5, 2005 Sep 29 - Who cited this? | PubMed ID: 16178559 | Fulltext

Mutational and structural analyses of the hinge region of membrane type 1-matrix metalloproteinase and enzyme processing.

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Osenkowski P, Meroueh SO, Pavel D, Mobashery S, and Fridman R

The Journal of biological chemistry 280(28):26160-8, 2005 Jul 15 - Who cited this? | PubMed ID: 15901740 | Fulltext

Design, synthesis, and evaluation of a mechanism-based inhibitor for gelatinase A.

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Ikejiri M, Bernardo MM, Meroueh SO, Brown S, Chang M, Fridman R, and Mobashery S

The Journal of organic chemistry 70(14):5709-12, 2005 Jul 8 - Who cited this? | PubMed ID: 15989356 | Fulltext

A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia.

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Gu Z, Cui J, Brown S, Fridman R, Mobashery S, Strongin AY, and Lipton SA

The Journal of neuroscience : the official journal of the Society for Neuroscience 25(27):6401-8, 2005 Jul 6 - Who cited this? | PubMed ID: 16000631 | Fulltext

Thymosin-beta4 modulates corneal matrix metalloproteinase levels and polymorphonuclear cell infiltration after alkali injury.

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Sosne G, Christopherson PL, Barrett RP, and Fridman R

Investigative ophthalmology & visual science 46(7):2388-95, 2005 Jul - Who cited this? | PubMed ID: 15980226 | Fulltext

Antimetastatic activity of a novel mechanism-based gelatinase inhibitor.

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Krüger A, Arlt MJ, Gerg M, Kopitz C, Bernardo MM, Chang M, Mobashery S, and Fridman R

Cancer research 65(9):3523-6, 2005 May 1 - Who cited this? | PubMed ID: 15867341 | Fulltext

Engaging nurse leaders in health services research.

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Bolton LB, Shihady IR, Bennett C, Broussard P, Fridman M, Fink A, Fridman R, Aydin C, Korst LM, and Gregory KD

The Journal of nursing administration 35(5):238-43, 2005 May - Who cited this? | PubMed ID: 15891487 | Fulltext

Cleavage at the stem region releases an active ectodomain of the membrane type 1 matrix metalloproteinase.

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Toth M, Osenkowski P, Hesek D, Brown S, Meroueh S, Sakr W, Mobashery S, and Fridman R

The Biochemical journal 387(Pt 2):497-506, 2005 Apr 15 - Who cited this? | PubMed ID: 15560752 | Fulltext

Matrix metalloproteinase inhibition impairs the processing, formation and mineralization of dental tissues during mouse molar development.

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Bourd-Boittin K, Fridman R, Fanchon S, Septier D, Goldberg M, and Menashi S

Experimental cell research 304(2):493-505, 2005 Apr 1 - Who cited this? | PubMed ID: 15748894 | Fulltext

Matrix metalloproteinase activity and osteoclasts in experimental prostate cancer bone metastasis tissue.

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Dong Z, Bonfil RD, Chinni S, Deng X, Trindade Filho JC, Bernardo M, Vaishampayan U, Che M, Sloane BF, Sheng S, Fridman R, and Cher ML

The American journal of pathology 166(4):1173-86, 2005 Apr - Who cited this? | PubMed ID: 15793297 | Fulltext

Tissue inhibitor of metalloproteinase-1 protects human breast epithelial cells from extrinsic cell death: a potential oncogenic activity of tissue inhibitor of metalloproteinase-1.

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Liu XW, Taube ME, Jung KK, Dong Z, Lee YJ, Roshy S, Sloane BF, Fridman R, and Kim HR

Cancer research 65(3):898-906, 2005 Feb 1 - Who cited this? | PubMed ID: 15705888 | Fulltext

Extracellular proteases as targets for treatment of cancer metastases.

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Lee M, Fridman R, and Mobashery S

Chemical Society reviews 33(7):401-9, 2004 Sep 10 - Who cited this? | PubMed ID: 15354221 | Fulltext

Processing, shedding, and endocytosis of membrane type 1-matrix metalloproteinase (MT1-MMP).

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Osenkowski P, Toth M, and Fridman R

Journal of cellular physiology 200(1):2-10, 2004 Jul - Who cited this? | PubMed ID: 15137052 | Fulltext

Differential inhibition of membrane type 3 (MT3)-matrix metalloproteinase (MMP) and MT1-MMP by tissue inhibitor of metalloproteinase (TIMP)-2 and TIMP-3 rgulates pro-MMP-2 activation.

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Zhao H, Bernardo MM, Osenkowski P, Sohail A, Pei D, Nagase H, Kashiwagi M, Soloway PD, DeClerck YA, and Fridman R

The Journal of biological chemistry 279(10):8592-601, 2004 Mar 5 - Who cited this? | PubMed ID: 14681236 | Fulltext

Glycosylation broadens the substrate profile of membrane type 1 matrix metalloproteinase.

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Wu YI, Munshi HG, Sen R, Snipas SJ, Salvesen GS, Fridman R, and Stack MS

The Journal of biological chemistry 279(9):8278-89, 2004 Feb 27 - Who cited this? | PubMed ID: 14670950 | Fulltext

Matrix metalloproteinaes and bone metastasis.

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Bonfil RD, Osenkowski P, Fridman R, and Cher ML

Cancer treatment and research 118:173-95, 2004 - Who cited this? | PubMed ID: 15043193 | Fulltext

Quest for selectivity in inhibition of matrix metalloproteinases.

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Brown S, Meroueh SO, Fridman R, and Mobashery S

Current topics in medicinal chemistry 4(12):1227-38, 2004 - Who cited this? | PubMed ID: 15320723 | Fulltext

Tissue inhibitor of metalloproteinase-1 protects human breast epithelial cells against intrinsic apoptotic cell death via the focal adhesion kinase/phosphatidylinositol 3-kinase and MAPK signaling pathway.

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Liu XW, Bernardo MM, Fridman R, and Kim HR

The Journal of biological chemistry 278(41):40364-72, 2003 Oct 10 - Who cited this? | PubMed ID: 12904305 | Fulltext

TIMP-2 (tissue inhibitor of metalloproteinase-2) regulates MMP-2 (matrix metalloproteinase-2) activity in the extracellular environment after pro-MMP-2 activation by MT1 (membrane type 1)-MMP.

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Bernardo MM and Fridman R

The Biochemical journal 374(Pt 3):739-45, 2003 Sep 15 - Who cited this? | PubMed ID: 12755684 | Fulltext

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