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Papers authored by Frank GD

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Endothelial nitric oxide synthase inhibits G12/13 and rho-kinase activated by the angiotensin II type-1 receptor: implication in vascular migration.

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Suzuki H, Kimura K, Shirai H, Eguchi K, Higuchi S, Hinoki A, Ishimaru K, Brailoiu E, Dhanasekaran DN, Stemmle LN, Fields TA, Frank GD, Autieri MV, and Eguchi S

Arteriosclerosis, thrombosis, and vascular biology 29(2):217-24, 2009 Feb - Who cited this? | PubMed ID: 19095998 | Fulltext

Central Role of Gq in the Hypertrophic Signal Transduction of Angiotensin II in Vascular Smooth Muscle Cells.

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Ohtsu H, Higuchi S, Shirai H, Eguchi K, Suzuki H, Hinoki A, Brailoiu E, Eckhart AD, Frank GD, and Eguchi S

Endocrinology 149(7):3569, 2008 Jul - Who cited this? | PubMed ID: 18356277 | Fulltext

Novel role of protein kinase C-delta Tyr 311 phosphorylation in vascular smooth muscle cell hypertrophy by angiotensin II.

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Nakashima H, Frank GD, Shirai H, Hinoki A, Higuchi S, Ohtsu H, Eguchi K, Sanjay A, Reyland ME, Dempsey PJ, Inagami T, and Eguchi S

Hypertension 51(2):232-8, 2008 Feb - Who cited this? | PubMed ID: 18180404 | Fulltext

Angiotensin II signal transduction through the AT1 receptor: novel insights into mechanisms and pathophysiology.

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Higuchi S, Ohtsu H, Suzuki H, Shirai H, Frank GD, and Eguchi S

Clinical science (London, England : 1979) 112(8):417-28, 2007 Apr - Who cited this? | PubMed ID: 17346243 | Fulltext

Activation of endothelial nitric oxide synthase by the angiotensin II type 1 receptor.

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Suzuki H, Eguchi K, Ohtsu H, Higuchi S, Dhobale S, Frank GD, Motley ED, and Eguchi S

Endocrinology 147(12):5914-20, 2006 Dec - Who cited this? | PubMed ID: 16980435 | Fulltext

Angiotensin II signal transduction through small GTP-binding proteins: mechanism and significance in vascular smooth muscle cells.

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Ohtsu H, Suzuki H, Nakashima H, Dhobale S, Frank GD, Motley ED, and Eguchi S

Hypertension 48(4):534-40, 2006 Oct - Who cited this? | PubMed ID: 16923993 | Fulltext

ADAM17 mediates epidermal growth factor receptor transactivation and vascular smooth muscle cell hypertrophy induced by angiotensin II.

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Ohtsu H, Dempsey PJ, Frank GD, Brailoiu E, Higuchi S, Suzuki H, Nakashima H, Eguchi K, and Eguchi S

Arteriosclerosis, thrombosis, and vascular biology 26(9):e133-7, 2006 Sep - Who cited this? | PubMed ID: 16840716 | Fulltext

Antagonism or synergism. Role of tyrosine phosphatases SHP-1 and SHP-2 in growth factor signaling.

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Wang N, Li Z, Ding R, Frank GD, Senbonmatsu T, Landon EJ, Inagami T, and Zhao ZJ

The Journal of biological chemistry 281(31):21878-83, 2006 Aug 4 - Who cited this? | PubMed ID: 16762922 | Fulltext

Current understanding of the mechanism and role of ROS in angiotensin II signal transduction.

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Suzuki H, Frank GD, Utsunomiya H, Higuchi S, and Eguchi S

Current pharmaceutical biotechnology 7(2):81-6, 2006 Apr - Who cited this? | PubMed ID: 16724941 | Fulltext

Angiotensin II regulates vascular and endothelial dysfunction: recent topics of Angiotensin II type-1 receptor signaling in the vasculature.

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Nakashima H, Suzuki H, Ohtsu H, Chao JY, Utsunomiya H, Frank GD, and Eguchi S

Current vascular pharmacology 4(1):67-78, 2006 Jan - Who cited this? | PubMed ID: 16472178 | Fulltext

Recent progress in signal transduction research of the angiotensin II type-1 receptor: protein kinases, vascular dysfunction and structural requirement.

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Suzuki H, Motley ED, Frank GD, Utsunomiya H, and Eguchi S

Current medicinal chemistry. Cardiovascular and hematological agents 3(4):305-22, 2005 Oct - Who cited this? | PubMed ID: 16250862 | Fulltext

Signal-crosstalk between Rho/ROCK and c-Jun NH2-terminal kinase mediates migration of vascular smooth muscle cells stimulated by angiotensin II.

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Ohtsu H, Mifune M, Frank GD, Saito S, Inagami T, Kim-Mitsuyama S, Takuwa Y, Sasaki T, Rothstein JD, Suzuki H, Nakashima H, Woolfolk EA, Motley ED, and Eguchi S

Arteriosclerosis, thrombosis, and vascular biology 25(9):1831-6, 2005 Sep - Who cited this? | PubMed ID: 15994438 | Fulltext

G protein coupling and second messenger generation are indispensable for metalloprotease-dependent, heparin-binding epidermal growth factor shedding through angiotensin II type-1 receptor.

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Mifune M, Ohtsu H, Suzuki H, Nakashima H, Brailoiu E, Dun NJ, Frank GD, Inagami T, Higashiyama S, Thomas WG, Eckhart AD, Dempsey PJ, and Eguchi S

The Journal of biological chemistry 280(28):26592-9, 2005 Jul 15 - Who cited this? | PubMed ID: 15905175 | Fulltext

The role of reactive oxygen species in insulin signaling in the vasculature.

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Frank GD, Eguchi S, and Motley ED

Antioxidants & redox signaling 7(7-8):1053-61, 2005 - Who cited this? | PubMed ID: 15998260 | Fulltext

Redox-dependent protein kinase regulation by angiotensin II: mechanistic insights and its pathophysiology.

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Ohtsu H, Frank GD, Utsunomiya H, and Eguchi S

Antioxidants & redox signaling 7(9-10):1315-26, 2005 - Who cited this? | PubMed ID: 16115037 | Fulltext

Signal transduction of betacellulin in growth and migration of vascular smooth muscle cells.

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Mifune M, Ohtsu H, Suzuki H, Frank GD, Inagami T, Utsunomiya H, Dempsey PJ, and Eguchi S

American journal of physiology. Cell physiology 287(3):C807-13, 2004 Sep - Who cited this? | PubMed ID: 15163624 | Fulltext

Activation of tyrosine kinases by reactive oxygen species in vascular smooth muscle cells: significance and involvement of EGF receptor transactivation by angiotensin II.

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Frank GD and Eguchi S

Antioxidants & redox signaling 5(6):771-80, 2003 Dec - Who cited this? | PubMed ID: 14588150 | Fulltext

Metalloprotease-dependent ErbB ligand shedding in mediating EGFR transactivation and vascular remodelling.

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Eguchi S, Frank GD, Mifune M, and Inagami T

Biochemical Society transactions 31(Pt 6):1198-202, 2003 Dec - Who cited this? | PubMed ID: 14641025 | Fulltext

Hydrogen peroxide inhibits insulin signaling in vascular smooth muscle cells.

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Gardner CD, Eguchi S, Reynolds CM, Eguchi K, Frank GD, and Motley ED

Experimental biology and medicine (Maywood, N.J.) 228(7):836-42, 2003 Jul - Who cited this? | PubMed ID: 12876303 | Fulltext

Distinct mechanisms of receptor and nonreceptor tyrosine kinase activation by reactive oxygen species in vascular smooth muscle cells: role of metalloprotease and protein kinase C-delta.

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Frank GD, Mifune M, Inagami T, Ohba M, Sasaki T, Higashiyama S, Dempsey PJ, and Eguchi S

Molecular and cellular biology 23(5):1581-9, 2003 Mar - Who cited this? | PubMed ID: 12588978 | Fulltext

Insulin-induced Akt activation is inhibited by angiotensin II in the vasculature through protein kinase C-alpha.

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Motley ED, Eguchi K, Gardner C, Hicks AL, Reynolds CM, Frank GD, Mifune M, Ohba M, and Eguchi S

Hypertension 41(3 Pt 2):775-80, 2003 Mar - Who cited this? | PubMed ID: 12623995 | Fulltext

Fruit-juice concentrate of Asian plum inhibits growth signals of vascular smooth muscle cells induced by angiotensin II.

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Utsunomiya H, Takekoshi S, Gato N, Utatsu H, Motley ED, Eguchi K, Fitzgerald TG, Mifune M, Frank GD, and Eguchi S

Life sciences 72(6):659-67, 2002 Dec 27 - Who cited this? | PubMed ID: 12467906 | Fulltext

Ligand-independent trans-activation of the platelet-derived growth factor receptor by reactive oxygen species requires protein kinase C-delta and c-Src.

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Saito S, Frank GD, Mifune M, Ohba M, Utsunomiya H, Motley ED, Inagami T, and Eguchi S

The Journal of biological chemistry 277(47):44695-700, 2002 Nov 22 - Who cited this? | PubMed ID: 12226102 | Fulltext

Angiotensin II-induced cardiac hypertrophy and hypertension are attenuated by epidermal growth factor receptor antisense.

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Kagiyama S, Eguchi S, Frank GD, Inagami T, Zhang YC, and Phillips MI

Circulation 106(8):909-12, 2002 Aug 20 - Who cited this? | PubMed ID: 12186792 | Fulltext

Metalloprotease inhibitor blocks angiotensin II-induced migration through inhibition of epidermal growth factor receptor transactivation.

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Saito S, Frank GD, Motley ED, Dempsey PJ, Utsunomiya H, Inagami T, and Eguchi S

Biochemical and biophysical research communications 294(5):1023-9, 2002 Jun 28 - Who cited this? | PubMed ID: 12074579 | Fulltext

Cyclosporin A inhibits angiotensin II-induced c-Jun NH(2)-terminal kinase activation but not protein synthesis in vascular smooth muscle cells.

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Saito S, Frank GD, Motley ED, Utsunomiya H, Inagami T, and Eguchi S

European journal of pharmacology 443(1-3):47-50, 2002 May 17 - Who cited this? | PubMed ID: 12044791 | Fulltext

Requirement of Ca(2+) and PKCdelta for Janus kinase 2 activation by angiotensin II: involvement of PYK2.

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Frank GD, Saito S, Motley ED, Sasaki T, Ohba M, Kuroki T, Inagami T, and Eguchi S

Molecular endocrinology (Baltimore, Md.) 16(2):367-77, 2002 Feb - Who cited this? | PubMed ID: 11818507 | Fulltext

Lysophosphatidylcholine inhibits insulin-induced Akt activation through protein kinase C-alpha in vascular smooth muscle cells.

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Motley ED, Kabir SM, Gardner CD, Eguchi K, Frank GD, Kuroki T, Ohba M, Yamakawa T, and Eguchi S

Hypertension 39(2 Pt 2):508-12, 2002 Feb - Who cited this? | PubMed ID: 11882599 | Fulltext

Signaling mechanisms of heparin-binding epidermal growth factor-like growth factor in vascular smooth muscle cells.

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Reynolds CM, Eguchi S, Frank GD, and Motley ED

Hypertension 39(2 Pt 2):525-9, 2002 Feb - Who cited this? | PubMed ID: 11882602 | Fulltext

Developing a successful hospitalist program.

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Frank GD and Gonzales D

Physician executive 28(6):32-6, 2002 - Who cited this? | PubMed ID: 12448140 | Fulltext

Protein kinase C inhibits insulin-induced Akt activation in vascular smooth muscle cells.

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Motley ED, Kabir SM, Eguchi K, Hicks AL, Gardner CD, Reynolds CM, Frank GD, and Eguchi S

Cellular and molecular biology (Noisy-le-Grand, France) 47(6):1059-62, 2001 Sep - Who cited this? | PubMed ID: 11785657 | Fulltext

Unique regulation of c-Jun N-terminal kinase by PYK2/CAK-beta in angiotensin II-stimulated vascular smooth muscle cells.

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Frank GD, Eguchi S, Motley ED, Sasaki T, and Inagami T

Biochemical and biophysical research communications 286(4):692-6, 2001 Aug 31 - Who cited this? | PubMed ID: 11520052 | Fulltext

Activation of MAPKs by angiotensin II in vascular smooth muscle cells. Metalloprotease-dependent EGF receptor activation is required for activation of ERK and p38 MAPK but not for JNK.

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Eguchi S, Dempsey PJ, Frank GD, Motley ED, and Inagami T

The Journal of biological chemistry 276(11):7957-62, 2001 Mar 16 - Who cited this? | PubMed ID: 11116149 | Fulltext

N-acetylcysteine inhibits angiotensin ii-mediated activation of extracellular signal-regulated kinase and epidermal growth factor receptor.

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Frank GD, Eguchi S, Inagami T, and Motley ED

Biochemical and biophysical research communications 280(4):1116-9, 2001 Feb 2 - Who cited this? | PubMed ID: 11162642 | Fulltext

Involvement of reactive oxygen species in the activation of tyrosine kinase and extracellular signal-regulated kinase by angiotensin II.

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Frank GD, Eguchi S, Yamakawa T, Tanaka S, Inagami T, and Motley ED

Endocrinology 141(9):3120-6, 2000 Sep - Who cited this? | PubMed ID: 10965882 | Fulltext

PYK2/CAKbeta represents a redox-sensitive tyrosine kinase in vascular smooth muscle cells.

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Frank GD, Motley ED, Inagami T, and Eguchi S

Biochemical and biophysical research communications 270(3):761-5, 2000 Apr 21 - Who cited this? | PubMed ID: 10772898 | Fulltext

Intracellular signaling of angiotensin II-induced p70 S6 kinase phosphorylation at Ser(411) in vascular smooth muscle cells. Possible requirement of epidermal growth factor receptor, Ras, extracellular signal-regulated kinase, and Akt.

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Eguchi S, Iwasaki H, Ueno H, Frank GD, Motley ED, Eguchi K, Marumo F, Hirata Y, and Inagami T

The Journal of biological chemistry 274(52):36843-51, 1999 Dec 24 - Who cited this? | PubMed ID: 10601235 | Fulltext

Epidermal growth factor receptor is indispensable for c-Fos expression and protein synthesis by angiotensin II.

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Eguchi S, Iwasaki H, Hirata Y, Frank GD, Motley ED, Yamakawa T, Numaguchi K, and Inagami T

European journal of pharmacology 376(1-2):203-6, 1999 Jul 2 - Who cited this? | PubMed ID: 10440105 | Fulltext

The level of CD4 surface protein influences T cell selection in the thymus.

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Frank GD and Parnes JR

Journal of immunology (Baltimore, Md. : 1950) 160(2):634-42, 1998 Jan 15 - Who cited this? | PubMed ID: 9551897 | Fulltext

Content and binding characteristics of the mitochondrial ATPase inhibitor, IF1, in the tissues of several slow and fast heart-rate homeothermic species and in two poikilotherms.

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Rouslin W, Frank GD, and Broge CW

Journal of bioenergetics and biomembranes 27(1):117-25, 1995 Feb - Who cited this? | PubMed ID: 7629043 | Fulltext

The effects of MHC gene dosage and allelic variation on T cell receptor selection.

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Berg LJ, Frank GD, and Davis MM

Cell 60(6):1043-53, 1990 Mar 23 - Who cited this? | PubMed ID: 2317862 | Fulltext

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