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Papers authored by Folkman J

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Doxycycline inhibits vascular leakage and prevents ovarian hyperstimulation syndrome in a murine model.

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Fainaru O, Hornstein MD, and Folkman J

Fertility and sterility 92(5):1701-5, 2009 Nov - Who cited this? | PubMed ID: 18937946 | Fulltext

Stem cell therapies benefit Alport syndrome.

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LeBleu V, Sugimoto H, Mundel TM, Gerami-Naini B, Finan E, Miller CA, Gattone VH, Lu L, Shield CF, Folkman J, and Kalluri R

Journal of the American Society of Nephrology : JASN 20(11):2359-70, 2009 Nov - Who cited this? | PubMed ID: 19833902 | Fulltext

Angiostatin regulates the expression of antiangiogenic and proapoptotic pathways via targeted inhibition of mitochondrial proteins.

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Lee TY, Muschal S, Pravda EA, Folkman J, Abdollahi A, and Javaherian K

Blood 114(9):1987-98, 2009 Aug 27 - Who cited this? | PubMed ID: 19465692 | Fulltext

Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1.

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Baek KH, Zaslavsky A, Lynch RC, Britt C, Okada Y, Siarey RJ, Lensch MW, Park IH, Yoon SS, Minami T, Korenberg JR, Folkman J, Daley GQ, Aird WC, Galdzicki Z, and Ryeom S

Nature 459(7250):1126-30, 2009 Jun 25 - Who cited this? | PubMed ID: 19458618 | Fulltext

Combined Vascular Endothelial Growth Factor Receptor and Epidermal Growth Factor Receptor (EGFR) Blockade Inhibits Tumor Growth in Xenograft Models of EGFR Inhibitor Resistance.

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Naumov GN, Nilsson MB, Cascone T, Briggs A, Straume O, Akslen LA, Lifshits E, Byers LA, Xu L, Wu HK, Jänne P, Kobayashi S, Halmos B, Tenen D, Tang XM, Engelman J,

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Clinical cancer research : an official journal of the American Association for Cancer Research 15(10):3484-94, 2009 May 15 - Who cited this? | PubMed ID: 19447865 | Fulltext

Platelets actively sequester angiogenesis regulators.

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Klement GL, Yip TT, Cassiola F, Kikuchi L, Cervi D, Podust V, Italiano JE, Wheatley E, Abou-Slaybi A, Bender E, Almog N, Kieran MW, and Folkman J

Blood 113(12):2835-42, 2009 Mar 19 - Who cited this? | PubMed ID: 19036702 | Fulltext

Matrigel cytometry: A novel method for quantifying angiogenesis in vivo.

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Adini A, Fainaru O, Udagawa T, Connor KM, Folkman J, and D'Amato RJ

Journal of immunological methods 342(1-2):78-81, 2009 Mar 15 - Who cited this? | PubMed ID: 19109967 | Fulltext

Pharmacological treatment of a diffuse arteriovenous malformation of the upper extremity in a child.

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Burrows PE, Mulliken JB, Fishman SJ, Klement GL, and Folkman J

The Journal of craniofacial surgery 20 Suppl 1:597-602, 2009 Mar - Who cited this? | PubMed ID: 19293678 | Fulltext

Role of endogenous angiogenesis inhibitors in Down syndrome.

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Ryeom S and Folkman J

The Journal of craniofacial surgery 20 Suppl 1:595-6, 2009 Mar - Who cited this? | PubMed ID: 19795527 | Fulltext

Transcriptional switch of dormant tumors to fast-growing angiogenic phenotype.

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Almog N, Ma L, Raychowdhury R, Schwager C, Erber R, Short S, Hlatky L, Vajkoczy P, Huber PE, Folkman J, and Abdollahi A

Cancer research 69(3):836-44, 2009 Feb 1 - Who cited this? | PubMed ID: 19176381 | Fulltext

Tumor dormancy due to failure of angiogenesis: role of the microenvironment.

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Naumov GN, Folkman J, and Straume O

Clinical & experimental metastasis 26(1):51-60, 2009 - Who cited this? | PubMed ID: 18563595 | Fulltext

Dendritic cells augment choroidal neovascularization.

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Nakai K, Fainaru O, Bazinet L, Pakneshan P, Benny O, Pravda E, Folkman J, and D'Amato RJ

Investigative ophthalmology & visual science 49(8):3666-70, 2008 Aug - Who cited this? | PubMed ID: 18408184 | Fulltext

Doxycycline induces membrane expression of VE-cadherin on endothelial cells and prevents vascular hyperpermeability.

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Fainaru O, Adini I, Benny O, Bazinet L, Pravda E, D'Amato R, and Folkman J

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2008 Jul 7 - Who cited this? | PubMed ID: 18606869 | Fulltext

An orally delivered small-molecule formulation with antiangiogenic and anticancer activity.

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Benny O, Fainaru O, Adini A, Cassiola F, Bazinet L, Adini I, Pravda E, Nahmias Y, Koirala S, Corfas G, D'Amato RJ, and Folkman J

Nature biotechnology, 2008 Jun 29 - Who cited this? | PubMed ID: 18587385 | Fulltext

Rosiglitazone and delayed onset of proliferative diabetic retinopathy.

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Shen LQ, Child A, Weber GM, Folkman J, and Aiello LP

Archives of ophthalmology 126(6):793, 2008 Jun - Who cited this? | PubMed ID: 18541841 | Fulltext

Phase II study of temozolomide, thalidomide, and celecoxib for newly diagnosed glioblastoma in adults.

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Kesari S, Schiff D, Henson JW, Muzikansky A, Gigas DC, Doherty L, Batchelor TT, Longtine JA, Ligon KL, Weaver S, Laforme A, Ramakrishna N, Black PM, Drappatz J, Ciampa A, Folkman J,

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Neuro-oncology 10(3):300-8, 2008 Jun - Who cited this? | PubMed ID: 18403492 | Fulltext

Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia.

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Kanasaki K, Palmsten K, Sugimoto H, Ahmad S, Hamano Y, Xie L, Parry S, Augustin HG, Gattone VH, Folkman J, Strauss JF, and Kalluri R

Nature, 2008 May 11 - Who cited this? | PubMed ID: 18469803 | Fulltext

Successful inhibition of intracranial human glioblastoma multiforme xenograft growth via systemic adenoviral delivery of soluble endostatin and soluble vascular endothelial growth factor receptor-2: laboratory investigation.

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Szentirmai O, Baker CH, Bullain SS, Lin N, Takahashi M, Folkman J, Mulligan RC, and Carter BS

Journal of neurosurgery 108(5):979, 2008 May - Who cited this? | PubMed ID: 18447716 | Fulltext

Linking Antibody Fc Domain to Endostatin Significantly Improves Endostatin Half-life and Efficacy.

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Lee TY, Tjin Tham Sjin RM, Movahedi S, Ahmed B, Pravda EA, Lo KM, Gillies SD, Folkman J, and Javaherian K

Clinical cancer research : an official journal of the American Association for Cancer Research 14(5):1487-93, 2008 Mar 1 - Who cited this? | PubMed ID: 18316573 | Fulltext

Dendritic cells support angiogenesis and promote lesion growth in a murine model of endometriosis.

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Fainaru O, Adini A, Benny O, Adini I, Short S, Bazinet L, Nakai K, Pravda E, Hornstein MD, D'Amato RJ, and Folkman J

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 22(2):522, 2008 Feb - Who cited this? | PubMed ID: 17873101 | Fulltext

Platelet-associated PF-4 as a biomarker of early tumor growth.

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Cervi D, Yip TT, Bhattacharya N, Podust VN, Peterson J, Abou-Slaybi A, Naumov GN, Bender E, Almog N, Italiano JE, Folkman J, and Klement GL

Blood 111(3):1201-7, 2008 Feb 1 - Who cited this? | PubMed ID: 17914028 | Fulltext

Angiogenesis is regulated by a novel mechanism: pro- and antiangiogenic proteins are organized into separate platelet {alpha} granules and differentially released.

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Italiano JE, Richardson JL, Patel-Hett S, Battinelli E, Zaslavsky A, Short S, Ryeom S, Folkman J, and Klement GL

Blood 111(3):1227-33, 2008 Feb 1 - Who cited this? | PubMed ID: 17962514 | Fulltext

2-Methoxyestradiol Inhibits Hypoxia-Inducible Factor-1{alpha} and Suppresses Growth of Lesions in a Mouse Model of Endometriosis.

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Becker CM, Rohwer N, Funakoshi T, Cramer T, Bernhardt W, Birsner A, Folkman J, and D'Amato RJ

The American journal of pathology 172(2):534-44, 2008 Feb - Who cited this? | PubMed ID: 18202195 | Fulltext

Potent antitumor effects of ZD6474 on neuroblastoma via dual targeting of tumor cells and tumor endothelium.

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Beaudry P, Nilsson M, Rioth M, Prox D, Poon D, Xu L, Zweidler-McKay P, Ryan A, Folkman J, Ryeom S, and Heymach J

Molecular cancer therapeutics 7(2):418-24, 2008 Feb - Who cited this? | PubMed ID: 18245671 | Fulltext

PPAR{alpha} agonist fenofibrate suppresses tumor growth through direct and indirect angiogenesis inhibition.

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Panigrahy D, Kaipainen A, Huang S, Butterfield CE, Barnés CM, Fannon M, Laforme AM, Chaponis DM, Folkman J, and Kieran MW

Proceedings of the National Academy of Sciences of the United States of America 105(3):985-90, 2008 Jan 22 - Who cited this? | PubMed ID: 18199835 | Fulltext

Better living through chemistry, constant monitoring, and prompt interventions: 26 years on home parenteral nutrition without major complications.

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Forchielli ML, Richardson D, Folkman J, Gura K, and Lo CW

Nutrition (Burbank, Los Angeles County, Calif.) 24(1):103-7, 2008 Jan - Who cited this? | PubMed ID: 17996420 | Fulltext

Malignant progression and blockade of angiogenesis in a murine transgenic model of neuroblastoma.

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Chesler L, Goldenberg DD, Seales IT, Satchi-Fainaro R, Grimmer M, Collins R, Struett C, Nguyen KN, Kim G, Tihan T, Bao Y, Brekken RA, Bergers G, Folkman J, and Weiss WA

Cancer research 67(19):9435-42, 2007 Oct 1 - Who cited this? | PubMed ID: 17909053 | Fulltext

Transcriptional network governing the angiogenic switch in human pancreatic cancer.

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Abdollahi A, Schwager C, Kleeff J, Esposito I, Domhan S, Peschke P, Hauser K, Hahnfeldt P, Hlatky L, Debus J, Peters JM, Friess H, Folkman J, and Huber PE

Proceedings of the National Academy of Sciences of the United States of America 104(31):12890, 2007 Jul 31 - Who cited this? | PubMed ID: 17652168 | Fulltext

Phase II study of metronomic chemotherapy for recurrent malignant gliomas in adults.

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Kesari S, Schiff D, Doherty L, Gigas DC, Batchelor TT, Muzikansky A, O'Neill A, Drappatz J, Chen-Plotkin AS, Ramakrishna N, Weiss SE, Levy B, Bradshaw J, Kracher J, Laforme A, Black PM,

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Neuro-oncology 9(3):354, 2007 Jul - Who cited this? | PubMed ID: 17452651 | Fulltext

Endothelial progenitor cells contribute to accelerated liver regeneration.

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Beaudry P, Hida Y, Udagawa T, Alwayn IP, Greene AK, Arsenault D, Folkman J, Heymach JV, Ryeom S, and Puder M

Journal of pediatric surgery 42(7):1190-8, 2007 Jul - Who cited this? | PubMed ID: 17618879 | Fulltext

Role of vascular endothelial growth factor A in children with acquired airway stenosis.

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Rahbar R, Brown LF, Folkman J, McGill TJ, Healy GB, Liu G, and Vargas SO

The Annals of otology, rhinology, and laryngology 116(6):430-5, 2007 Jun - Who cited this? | PubMed ID: 17672245 | Fulltext

Blood-based biomarkers of SU11248 activity and clinical outcome in patients with metastatic imatinib-resistant gastrointestinal stromal tumor.

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Norden-Zfoni A, Desai J, Manola J, Beaudry P, Force J, Maki R, Folkman J, Bello C, Baum C, DePrimo SE, Shalinsky DR, Demetri GD, and Heymach JV

Clinical cancer research : an official journal of the American Association for Cancer Research 13(9):2643-50, 2007 May 1 - Who cited this? | PubMed ID: 17473195 | Fulltext

Angiogenesis: an organizing principle for drug discovery?.

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Folkman J

Nature reviews. Drug discovery 6(4):273-86, 2007 Apr - Who cited this? | PubMed ID: 17396134 | Fulltext

Is angiogenesis an organizing principle in biology and medicine?.

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Folkman J

Journal of pediatric surgery 42(1):1-11, 2007 Jan - Who cited this? | PubMed ID: 17208533 | Fulltext

PPARalpha deficiency in inflammatory cells suppresses tumor growth.

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Kaipainen A, Kieran MW, Huang S, Butterfield C, Bielenberg D, Mostoslavsky G, Mulligan R, Folkman J, and Panigrahy D

PLoS ONE 2(2):e260, 2007 - Who cited this? | PubMed ID: 17327920 | Fulltext

The placenta theory and the origin of infantile hemangioma.

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Barnés CM, Christison-Lagay EA, and Folkman J

Lymphatic research and biology 5(4):245-56, 2007 - Who cited this? | PubMed ID: 18370915 | Fulltext

Sustained regression of tumors upon MYC inactivation requires p53 or thrombospondin-1 to reverse the angiogenic switch.

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Giuriato S, Ryeom S, Fan AC, Bachireddy P, Lynch RC, Rioth MJ, van Riggelen J, Kopelman AM, Passegué E, Tang F, Folkman J, and Felsher DW

Proceedings of the National Academy of Sciences of the United States of America 103(44):16266, 2006 Oct 31 - Who cited this? | PubMed ID: 17056717 | Fulltext

Inhibition of p53 response in tumor stroma improves efficacy of anticancer treatment by increasing antiangiogenic effects of chemotherapy and radiotherapy in mice.

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Burdelya LG, Komarova EA, Hill JE, Browder T, Tararova ND, Mavrakis L, DiCorleto PE, Folkman J, and Gudkov AV

Cancer research 66(19):9356, 2006 Oct 1 - Who cited this? | PubMed ID: 17018587 | Fulltext

Tumor suppression by p53 is mediated in part by the antiangiogenic activity of endostatin and tumstatin.

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Folkman J

Science's STKE : signal transduction knowledge environment 2006(354):pe35, 2006 Sep 26 - Who cited this? | PubMed ID: 17003465 | Fulltext

An endogenous inhibitor of angiogenesis derived from a transitional cell carcinoma: clipped beta2-glycoprotein-I.

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Beecken WD, Engl T, Ringel EM, Camphausen K, Michaelis M, Jonas D, Folkman J, Shing Y, and Blaheta RA

Annals of surgical oncology 13(9):1241-51, 2006 Sep - Who cited this? | PubMed ID: 16955386 | Fulltext

Role of angiogenesis in human tumor dormancy: animal models of the angiogenic switch.

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Naumov GN, Akslen LA, and Folkman J

Cell cycle (Georgetown, Tex.) 5(16):1779-87, 2006 Aug - Who cited this? | PubMed ID: 16931911 | Fulltext

Reversal of parenteral nutrition-associated liver disease in two infants with short bowel syndrome using parenteral fish oil: implications for future management.

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Gura KM, Duggan CP, Collier SB, Jennings RW, Folkman J, Bistrian BR, and Puder M

Pediatrics 118(1), 2006 Jul - Who cited this? | PubMed ID: 16818533 | Fulltext

Doxycycline treatment for lymphangioleiomyomatosis with urinary monitoring for MMPs.

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Moses MA, Harper J, and Folkman J

The New England journal of medicine 354(24):2621-2, 2006 Jun 15 - Who cited this? | PubMed ID: 16775248 | Fulltext

A novel noninvasive model of endometriosis for monitoring the efficacy of antiangiogenic therapy.

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Becker CM, Wright RD, Satchi-Fainaro R, Funakoshi T, Folkman J, Kung AL, and D'Amato RJ

The American journal of pathology 168(6):2074, 2006 Jun - Who cited this? | PubMed ID: 16723720 | Fulltext

Endostatin therapy reveals a U-shaped curve for antitumor activity.

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Tjin Tham Sjin RM, Naspinski J, Birsner AE, Li C, Chan R, Lo KM, Gillies S, Zurakowski D, Folkman J, Samulski J, and Javaherian K

Cancer gene therapy 13(6):619-27, 2006 Jun - Who cited this? | PubMed ID: 16456550 | Fulltext

Thalidomide for multiple myeloma.

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Folkman J and Rogers MS

The New England journal of medicine 354(22):2389-90; author reply 2389-90, 2006 Jun 1 - Who cited this? | PubMed ID: 16738279 | Fulltext

Prolonged dormancy of human liposarcoma is associated with impaired tumor angiogenesis.

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Almog N, Henke V, Flores L, Hlatky L, Kung AL, Wright RD, Berger R, Hutchinson L, Naumov GN, Bender E, Akslen LA, Achilles EG, and Folkman J

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20(7):947, 2006 May - Who cited this? | PubMed ID: 16638967 | Fulltext

Antiangiogenesis in cancer therapy--endostatin and its mechanisms of action.

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Folkman J

Experimental cell research 312(5):594-607, 2006 Mar 10 - Who cited this? | PubMed ID: 16376330 | Fulltext

A model of human tumor dormancy: an angiogenic switch from the nonangiogenic phenotype.

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Naumov GN, Bender E, Zurakowski D, Kang SY, Sampson D, Flynn E, Watnick RS, Straume O, Akslen LA, Folkman J, and Almog N

Journal of the National Cancer Institute 98(5):316, 2006 Mar 1 - Who cited this? | PubMed ID: 16507828 | Fulltext

Platelets and platelet adhesion support angiogenesis while preventing excessive hemorrhage.

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Kisucka J, Butterfield CE, Duda DG, Eichenberger SC, Saffaripour S, Ware J, Ruggeri ZM, Jain RK, Folkman J, and Wagner DD

Proceedings of the National Academy of Sciences of the United States of America 103(4):855-60, 2006 Jan 24 - Who cited this? | PubMed ID: 16418262 | Fulltext

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