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Papers authored by Florea BI

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Syringolin A selectively labels the 20 S proteasome in murine EL4 and wild-type and bortezomib-adapted leukaemic cell lines.

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Clerc J, Florea BI, Kraus M, Groll M, Huber R, Bachmann AS, Dudler R, Driessen C, Overkleeft HS, and Kaiser M

Chembiochem : a European journal of chemical biology 10(16):2638-43, 2009 Nov 2 - Who cited this? | PubMed ID: 19746508 | Fulltext

O-GlcNAc peptide epoxyketones are recognized by mammalian proteasomes.

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Witte MD, Florea BI, Verdoes M, Adeyanju O, Van der Marel GA, and Overkleeft HS

Journal of the American Chemical Society 131(34):12064-5, 2009 Sep 2 - Who cited this? | PubMed ID: 19658393 | Fulltext

Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment.

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Maynard CJ, Böttcher C, Ortega Z, Smith R, Florea BI, Díaz-Hernández M, Brundin P, Overkleeft HS, Li JY, Lucas JJ, and Dantuma NP

Proceedings of the National Academy of Sciences of the United States of America 106(33):13986-91, 2009 Aug 18 - Who cited this? | PubMed ID: 19666572 | Fulltext

The Ku80 carboxy terminus stimulates joining and artemis-mediated processing of DNA ends.

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Weterings E, Verkaik NS, Keijzers G, Florea BI, Wang SY, Ortega LG, Uematsu N, Chen DJ, and van Gent DC

Molecular and cellular biology 29(5):1134-42, 2009 Mar - Who cited this? | PubMed ID: 19103741 | Fulltext

Receptor-mediated targeting of cathepsins in professional antigen presenting cells.

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Hillaert U, Verdoes M, Florea BI, Saragliadis A, Habets KL, Kuiper J, Van Calenbergh S, Ossendorp F, van der Marel GA, Driessen C, and Overkleeft HS

Angewandte Chemie (International ed. in English) 48(9):1629-32, 2009 - Who cited this? | PubMed ID: 19156780 | Fulltext

Receptor-mediated targeting of cathepsins in professional antigen presenting cells.

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Hillaert U, Verdoes M, Florea BI, Saragliadis A, Habets KL, Kuiper J, Van Calenbergh S, Ossendorp F, van der Marel GA, Driessen C, and Overkleeft HS

Angewandte Chemie (International ed. in English) 48(14):2442, 2009 - Who cited this? | PubMed ID: 19294667 | Fulltext

Azido-BODIPY Acid Reveals Quantitative Staudinger-Bertozzi Ligation in Two-Step Activity-Based Proteasome Profiling.

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Verdoes M, Florea BI, Hillaert U, Willems LI, van der Linden WA, Sae-Heng M, Filippov DV, Kisselev AF, van der Marel GA, and Overkleeft HS

Chembiochem : a European journal of chemical biology, 2008 Jul 4 - Who cited this? | PubMed ID: 18600815 | Fulltext

Bodipy-VAD-Fmk, a useful tool to study yeast peptide N-glycanase activity.

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Witte MD, Descals CV, de Lavoir SV, Florea BI, van der Marel GA, and Overkleeft HS

Organic & biomolecular chemistry 5(22):3690-7, 2007 Nov 21 - Who cited this? | PubMed ID: 17971999 | Fulltext

Acetylene functionalized BODIPY dyes and their application in the synthesis of activity based proteasome probes.

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Verdoes M, Hillaert U, Florea BI, Sae-Heng M, Risseeuw MD, Filippov DV, van der Marel GA, and Overkleeft HS

Bioorganic & medicinal chemistry letters 17(22):6169-71, 2007 Nov 15 - Who cited this? | PubMed ID: 17888658 | Fulltext

Mixing of peptides and electrophilic traps gives rise to potent, broad-spectrum proteasome inhibitors.

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Verdoes M, Florea BI, van der Linden WA, Renou D, van den Nieuwendijk AM, van der Marel GA, and Overkleeft HS

Organic & biomolecular chemistry 5(9):1416-26, 2007 May 7 - Who cited this? | PubMed ID: 17464411 | Fulltext

Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4.

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Mari PO, Florea BI, Persengiev SP, Verkaik NS, Brüggenwirth HT, Modesti M, Giglia-Mari G, Bezstarosti K, Demmers JA, Luider TM, Houtsmuller AB, and van Gent DC

Proceedings of the National Academy of Sciences of the United States of America 103(49):18597, 2006 Dec 5 - Who cited this? | PubMed ID: 17124166 | Fulltext

A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo.

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Verdoes M, Florea BI, Menendez-Benito V, Maynard CJ, Witte MD, van der Linden WA, van den Nieuwendijk AM, Hofmann T, Berkers CR, van Leeuwen FW, Groothuis TA, Leeuwenburgh MA, Ovaa H, Neefjes JJ, Filippov DV, van der Marel GA,

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Chemistry & biology 13(11):1217-26, 2006 Nov - Who cited this? | PubMed ID: 17114003 | Fulltext

Enhancement of bronchial octreotide absorption by chitosan and N-trimethyl chitosan shows linear in vitro/in vivo correlation.

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Florea BI, Thanou M, Junginger HE, and Borchard G

Journal of controlled release : official journal of the Controlled Release Society 110(2):353-61, 2006 Jan 10 - Who cited this? | PubMed ID: 16269199 | Fulltext

Chemical proteomics profiling of proteasome activity.

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Verdoes M, Berkers CR, Florea BI, van Swieten PF, Overkleeft HS, and Ovaa H

Methods in molecular biology (Clifton, N.J.) 328:51-69, 2006 - Who cited this? | PubMed ID: 16785641 | Fulltext

Identification of an internalising peptide in differentiated Calu-3 cells by phage display technology; application to gene delivery to the airways.

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Florea BI, Molenaar TJ, Bot I, Michon IN, Kuiper J, Van Berkel TJ, Junginger HE, Biessen EA, and Borchard G

Journal of drug targeting 11(7):383-90, 2003 Aug - Who cited this? | PubMed ID: 15203927 | Fulltext

Drug transport and metabolism characteristics of the human airway epithelial cell line Calu-3.

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Florea BI, Cassara ML, Junginger HE, and Borchard G

Journal of controlled release : official journal of the Controlled Release Society 87(1-3):131-8, 2003 Feb 21 - Who cited this? | PubMed ID: 12618029 | Fulltext

Transport and local metabolism of budesonide and fluticasone propionate in a human bronchial epithelial cell line (Calu-3).

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Borchard G, Cassará ML, Roemelé PE, Florea BI, and Junginger HE

Journal of pharmaceutical sciences 91(6):1561-7, 2002 Jun - Who cited this? | PubMed ID: 12115854 | Fulltext

Apoptosis induced by extracellular ATP in the mouse neuroblastoma cell line N1E-115: studies on involvement of P2 receptors and adenosine.

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Schrier SM, Florea BI, Mulder GJ, Nagelkerke JF, and IJzerman AP

Biochemical pharmacology 63(6):1119-26, 2002 Mar 15 - Who cited this? | PubMed ID: 11931844 | Fulltext

Quaternized chitosan oligomers as novel gene delivery vectors in epithelial cell lines.

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Thanou M, Florea BI, Geldof M, Junginger HE, and Borchard G

Biomaterials 23(1):153-9, 2002 Jan - Who cited this? | PubMed ID: 11762833 | Fulltext

Transfection efficiency and toxicity of polyethylenimine in differentiated Calu-3 and nondifferentiated COS-1 cell cultures.

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Florea BI, Meaney C, Junginger HE, and Borchard G

AAPS pharmSci 4(3):E12, 2002 - Who cited this? | PubMed ID: 12423061 | Fulltext

Evidence of P-glycoprotein mediated apical to basolateral transport of flunisolide in human broncho-tracheal epithelial cells (Calu-3).

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Florea BI, van der Sandt IC, Schrier SM, Kooiman K, Deryckere K, de Boer AG, Junginger HE, and Borchard G

British journal of pharmacology 134(7):1555-63, 2001 Dec - Who cited this? | PubMed ID: 11724763 | Fulltext

N-trimethylated chitosan chloride (TMC) improves the intestinal permeation of the peptide drug buserelin in vitro (Caco-2 cells) and in vivo (rats).

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Thanou M, Florea BI, Langemeÿer MW, Verhoef JC, and Junginger HE

Pharmaceutical research 17(1):27-31, 2000 Jan - Who cited this? | PubMed ID: 10714604 | Fulltext

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