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Papers authored by Flavell RA

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Defective survival of naive CD8(+) T lymphocytes in the absence of the beta3 regulatory subunit of voltage-gated calcium channels.

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Jha MK, Badou A, Meissner M, McRory JE, Freichel M, Flockerzi V, and Flavell RA

Nature immunology 10(12):1275-82, 2009 Dec - Who cited this? | PubMed ID: 19838200 | Fulltext

A non-redundant role for MKP5 in limiting ROS production and preventing LPS-induced vascular injury.

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Qian F, Deng J, Cheng N, Welch EJ, Zhang Y, Malik AB, Flavell RA, Dong C, and Ye RD

The EMBO journal 28(19):2896-907, 2009 Oct 7 - Who cited this? | PubMed ID: 19696743 | Fulltext

Thymic self-reactivity selects natural interleukin 17-producing T cells that can regulate peripheral inflammation.

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Marks BR, Nowyhed HN, Choi JY, Poholek AC, Odegard JM, Flavell RA, and Craft J

Nature immunology 10(10):1125-32, 2009 Oct - Who cited this? | PubMed ID: 19734905 | Fulltext

How diverse--CD4 effector T cells and their functions.

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Wan YY and Flavell RA

Journal of molecular cell biology 1(1):20-36, 2009 Oct - Who cited this? | PubMed ID: 19482777 | Fulltext

IL-10 signaling blockade controls murine west nile virus infection.

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Bai F, Town T, Qian F, Wang P, Kamanaka M, Connolly TM, Gate D, Montgomery RR, Flavell RA, and Fikrig E

PLoS pathogens 5(10):e1000610, 2009 Oct - Who cited this? | PubMed ID: 19816558 | Fulltext

E3 ubiquitin ligase GRAIL controls primary T cell activation and oral tolerance.

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Kriegel MA, Rathinam C, and Flavell RA

Proceedings of the National Academy of Sciences of the United States of America 106(39):16770-5, 2009 Sep 29 - Who cited this? | PubMed ID: 19805371 | Fulltext

Inflammatory regulation by TLR3 in acute hepatitis.

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Xiao X, Zhao P, Rodriguez-Pinto D, Qi D, Henegariu O, Alexopoulou L, Flavell RA, Wong FS, and Wen L

Journal of immunology (Baltimore, Md. : 1950) 183(6):3712-9, 2009 Sep 15 - Who cited this? | PubMed ID: 19710451 | Fulltext

SHIP represses the generation of IL-3-induced M2 macrophages by inhibiting IL-4 production from basophils.

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Kuroda E, Ho V, Ruschmann J, Antignano F, Hamilton M, Rauh MJ, Antov A, Flavell RA, Sly LM, and Krystal G

Journal of immunology (Baltimore, Md. : 1950) 183(6):3652-60, 2009 Sep 15 - Who cited this? | PubMed ID: 19710468 | Fulltext

Signal transduction cross talk mediated by jun N-terminal kinase-interacting protein and insulin receptor substrate scaffold protein complexes.

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Standen CL, Kennedy NJ, Flavell RA, and Davis RJ

Molecular and cellular biology 29(17):4831-40, 2009 Sep - Who cited this? | PubMed ID: 19564410 | Fulltext

Regulatory T cells that become autoaggressive.

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Hawiger D and Flavell RA

Nature immunology 10(9):938-9, 2009 Sep - Who cited this? | PubMed ID: 19692993 | Fulltext

Loss of Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4) Reveals a Requirement for MAPK Signalling in Mouse Sex Determination.

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Bogani D, Siggers P, Brixey R, Warr N, Beddow S, Edwards J, Williams D, Wilhelm D, Koopman P, Flavell RA, Chi H, Ostrer H, Wells S, Cheeseman M, and Greenfield A

PLoS biology 7(9):e1000196, 2009 Sep - Who cited this? | PubMed ID: 19753101 | Fulltext

Roles of Ca(v) channels and AHNAK1 in T cells: the beauty and the beast.

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Matza D and Flavell RA

Immunological reviews 231(1):257-64, 2009 Sep - Who cited this? | PubMed ID: 19754902 | Fulltext

Correction: Malarial Hemozoin Activates the NLRP3 Inflammasome through Lyn and Syk Kinases.

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Shio MT, Eisenbarth SC, Savaria M, Vinet AF, Bellemare MJ, Harder KW, Sutterwala FS, Bohle DS, Descoteaux A, Flavell RA, and Olivier M

PLoS pathogens 5(9), 2009 Sep - Who cited this? | PubMed ID: 19834603 | Fulltext

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes.

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Galluzzi L, Aaronson SA, Abrams J, Alnemri ES, Andrews DW, Baehrecke EH, Bazan NG, Blagosklonny MV, Blomgren K, Borner C, Bredesen DE, Brenner C, Castedo M, Cidlowski JA, Ciechanover A, Cohen GM,

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Cell death and differentiation 16(8):1093-107, 2009 Aug - Who cited this? | PubMed ID: 19373242 | Fulltext

Salmonella Typhimurium Type III Secretion Effectors Stimulate Innate Immune Responses in Cultured Epithelial Cells.

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Bruno VM, Hannemann S, Lara-Tejero M, Flavell RA, Kleinstein SH, and Galán JE

PLoS pathogens 5(8):e1000538, 2009 Aug - Who cited this? | PubMed ID: 19662166 | Fulltext

Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases.

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Tiemi Shio M, Eisenbarth SC, Savaria M, Vinet AF, Bellemare MJ, Harder KW, Sutterwala FS, Bohle DS, Descoteaux A, Flavell RA, and Olivier M

PLoS pathogens 5(8):e1000559, 2009 Aug - Who cited this? | PubMed ID: 19696895 | Fulltext

Anti-inflammatory and pro-inflammatory roles of TGF-beta, IL-10, and IL-22 in immunity and autoimmunity.

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Sanjabi S, Zenewicz LA, Kamanaka M, and Flavell RA

Current opinion in pharmacology 9(4):447-53, 2009 Aug - Who cited this? | PubMed ID: 19481975 | Fulltext

Humanized mice for modeling human infectious disease: challenges, progress, and outlook.

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Legrand N, Ploss A, Balling R, Becker PD, Borsotti C, Brezillon N, Debarry J, de Jong Y, Deng H, Di Santo JP, Eisenbarth S, Eynon E, Flavell RA, Guzman CA, Huntington ND, Kremsdorf D,

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Cell host & microbe 6(1):5-9, 2009 Jul 23 - Who cited this? | PubMed ID: 19616761 | Fulltext

Virus binding to a plasma membrane receptor triggers interleukin-1 alpha-mediated proinflammatory macrophage response in vivo.

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Di Paolo NC, Miao EA, Iwakura Y, Murali-Krishna K, Aderem A, Flavell RA, Papayannopoulou T, and Shayakhmetov DM

Immunity 31(1):110-21, 2009 Jul 17 - Who cited this? | PubMed ID: 19576795 | Fulltext

Opposing effects of TGF-beta and IL-15 cytokines control the number of short-lived effector CD8+ T cells.

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Sanjabi S, Mosaheb MM, and Flavell RA

Immunity 31(1):131-44, 2009 Jul 17 - Who cited this? | PubMed ID: 19604492 | Fulltext

Pharmacological postconditioning effect of muramyl dipeptide is mediated through RIP2 and TAK1.

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Sicard P, Jacquet S, Kobayashi KS, Flavell RA, and Marber MS

Cardiovascular research 83(2):277-84, 2009 Jul 15 - Who cited this? | PubMed ID: 19213760 | Fulltext

Amino acid polymorphisms altering the glycosylation of IL-2 do not protect from type 1 diabetes in the NOD mouse.

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Kamanaka M, Rainbow D, Schuster-Gossler K, Eynon EE, Chervonsky AV, Wicker LS, and Flavell RA

Proceedings of the National Academy of Sciences of the United States of America 106(27):11236-40, 2009 Jul 7 - Who cited this? | PubMed ID: 19549859 | Fulltext

The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR.

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Liu G, Burns S, Huang G, Boyd K, Proia RL, Flavell RA, and Chi H

Nature immunology 10(7):769-77, 2009 Jul - Who cited this? | PubMed ID: 19483717 | Fulltext

Role of T cell TGF-beta signaling in intestinal cytokine responses and helminthic immune modulation.

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Ince MN, Elliott DE, Setiawan T, Metwali A, Blum A, Chen HL, Urban JF, Flavell RA, and Weinstock JV

European journal of immunology 39(7):1870-8, 2009 Jul - Who cited this? | PubMed ID: 19544487 | Fulltext

Requirement for AHNAK1-mediated calcium signaling during T lymphocyte cytolysis.

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Matza D, Badou A, Jha MK, Willinger T, Antov A, Sanjabi S, Kobayashi KS, Marchesi VT, and Flavell RA

Proceedings of the National Academy of Sciences of the United States of America 106(24):9785-90, 2009 Jun 16 - Who cited this? | PubMed ID: 19497879 | Fulltext

A protective function for interleukin 17A in T cell-mediated intestinal inflammation.

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O'Connor W, Kamanaka M, Booth CJ, Town T, Nakae S, Iwakura Y, Kolls JK, and Flavell RA

Nature immunology 10(6):603-9, 2009 Jun - Who cited this? | PubMed ID: 19448631 | Fulltext

Inflammasome-mediated regulation of hepatic stellate cells.

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Watanabe A, Sohail MA, Gomes DA, Hashmi A, Nagata J, Sutterwala FS, Mahmood S, Jhandier MN, Shi Y, Flavell RA, and Mehal WZ

American journal of physiology. Gastrointestinal and liver physiology 296(6):G1248-57, 2009 Jun - Who cited this? | PubMed ID: 19359429 | Fulltext

Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacy.

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Demento SL, Eisenbarth SC, Foellmer HG, Platt C, Caplan MJ, Mark Saltzman W, Mellman I, Ledizet M, Fikrig E, Flavell RA, and Fahmy TM

Vaccine 27(23):3013-21, 2009 May 18 - Who cited this? | PubMed ID: 19428913 | Fulltext

Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis.

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Lee CG, Hartl D, Lee GR, Koller B, Matsuura H, Da Silva CA, Sohn MH, Cohn L, Homer RJ, Kozhich AA, Humbles A, Kearley J, Coyle A, Chupp G, Reed J, Flavell RA,

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The Journal of experimental medicine 206(5):1149-66, 2009 May 11 - Who cited this? | PubMed ID: 19414556 | Fulltext

T cell sensitivity to TGF-beta is required for the effector function but not the generation of splenic CD8+ regulatory T cells induced via the injection of antigen into the anterior chamber.

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Cone RE, Chattopadhyay S, Sharafieh R, Lemire Y, O'Rourke J, Flavell RA, and Clark RB

International immunology 21(5):567-74, 2009 May - Who cited this? | PubMed ID: 19325036 | Fulltext

CD4 T-cell differentiation and inflammatory bowel disease.

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Zenewicz LA, Antov A, and Flavell RA

Trends in molecular medicine 15(5):199-207, 2009 May - Who cited this? | PubMed ID: 19362058 | Fulltext

RIG-I-mediated Activation of p38 MAPK Is Essential for Viral Induction of Interferon and Activation of Dendritic Cells: DEPENDENCE ON TRAF2 AND TAK1.

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Mikkelsen SS, Jensen SB, Chiliveru S, Melchjorsen J, Julkunen I, Gaestel M, Arthur JS, Flavell RA, Ghosh S, and Paludan SR

The Journal of biological chemistry 284(16):10774-82, 2009 Apr 17 - Who cited this? | PubMed ID: 19224920 | Fulltext

Activin a promotes the TGF-beta-induced conversion of CD4+CD25- T cells into Foxp3+ induced regulatory T cells.

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Huber S, Stahl FR, Schrader J, Lüth S, Presser K, Carambia A, Flavell RA, Werner S, Blessing M, Herkel J, and Schramm C

Journal of immunology (Baltimore, Md. : 1950) 182(8):4633-40, 2009 Apr 15 - Who cited this? | PubMed ID: 19342638 | Fulltext

Acidic mammalian chitinase regulates epithelial cell apoptosis via a chitinolytic-independent mechanism.

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Hartl D, He CH, Koller B, Da Silva CA, Kobayashi Y, Lee CG, Flavell RA, and Elias JA

Journal of immunology (Baltimore, Md. : 1950) 182(8):5098-106, 2009 Apr 15 - Who cited this? | PubMed ID: 19342690 | Fulltext

ICOS controls effector function but not trafficking receptor expression of kidney-infiltrating effector T cells in murine lupus.

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Odegard JM, DiPlacido LD, Greenwald L, Kashgarian M, Kono DH, Dong C, Flavell RA, and Craft J

Journal of immunology (Baltimore, Md. : 1950) 182(7):4076-84, 2009 Apr 1 - Who cited this? | PubMed ID: 19299705 | Fulltext

Activation of nucleotide oligomerization domain 2 exacerbates a murine model of proteoglycan-induced arthritis.

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Rosenzweig HL, Jann MM, Glant TT, Martin TM, Planck SR, van Eden W, van Kooten PJ, Flavell RA, Kobayashi KS, Rosenbaum JT, and Davey MP

Journal of leukocyte biology 85(4):711-8, 2009 Apr - Who cited this? | PubMed ID: 19129483 | Fulltext

Antigen presentation on artificial acellular substrates: modular systems for flexible, adaptable immunotherapy.

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Steenblock ER, Wrzesinski SH, Flavell RA, and Fahmy TM

Expert opinion on biological therapy 9(4):451-64, 2009 Apr - Who cited this? | PubMed ID: 19344282 | Fulltext

How are T(H)1 and T(H)2 effector cells made?.

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Amsen D, Spilianakis CG, and Flavell RA

Current opinion in immunology 21(2):153-60, 2009 Apr - Who cited this? | PubMed ID: 19375293 | Fulltext

B cells suppress the inflammatory response in a mouse model of primary biliary cirrhosis.

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Moritoki Y, Zhang W, Tsuneyama K, Yoshida K, Wakabayashi K, Yang GX, Bowlus C, Ridgway WM, Ueno Y, Ansari AA, Coppel RL, Mackay IR, Flavell RA, Gershwin ME, and Lian ZX

Gastroenterology 136(3):1037-47, 2009 Mar - Who cited this? | PubMed ID: 19118554 | Fulltext

Role of TLR3 in the immunogenicity of replicon plasmid-based vaccines.

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Diebold SS, Schulz O, Alexopoulou L, Leitner WW, Flavell RA, and Reis e Sousa C

Gene therapy 16(3):359-66, 2009 Mar - Who cited this? | PubMed ID: 19052633 | Fulltext

An essential role of the Forkhead-box transcription factor Foxo1 in control of T cell homeostasis and tolerance.

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Ouyang W, Beckett O, Flavell RA, and Li MO

Immunity 30(3):358-71, 2009 Mar - Who cited this? | PubMed ID: 19285438 | Fulltext

Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis.

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Ma DK, Jang MH, Guo JU, Kitabatake Y, Chang ML, Pow-Anpongkul N, Flavell RA, Lu B, Ming GL, and Song H

Science (New York, N.Y.) 323(5917):1074-7, 2009 Feb 20 - Who cited this? | PubMed ID: 19119186 | Fulltext

Role of MKK3-p38 MAPK signalling in the development of type 2 diabetes and renal injury in obese db/db mice.

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Lim AK, Nikolic-Paterson DJ, Ma FY, Ozols E, Thomas MC, Flavell RA, Davis RJ, and Tesch GH

Diabetologia 52(2):347-58, 2009 Feb - Who cited this? | PubMed ID: 19066844 | Fulltext

The different faces of Notch in T-helper-cell differentiation.

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Amsen D, Antov A, and Flavell RA

Nature reviews. Immunology 9(2):116-24, 2009 Feb - Who cited this? | PubMed ID: 19165228 | Fulltext

Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome.

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Imaeda AB, Watanabe A, Sohail MA, Mahmood S, Mohamadnejad M, Sutterwala FS, Flavell RA, and Mehal WZ

The Journal of clinical investigation 119(2):305-14, 2009 Feb - Who cited this? | PubMed ID: 19164858 | Fulltext

Toll-like receptor 7 mitigates lethal West Nile encephalitis via interleukin 23-dependent immune cell infiltration and homing.

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Town T, Bai F, Wang T, Kaplan AT, Qian F, Montgomery RR, Anderson JF, Flavell RA, and Fikrig E

Immunity 30(2):242-53, 2009 Feb - Who cited this? | PubMed ID: 19200759 | Fulltext

Induction of Hepatitis by JNK-Mediated Expression of TNF-alpha.

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Das M, Sabio G, Jiang F, Rincón M, Flavell RA, and Davis RJ

Cell 136(2):249-60, 2009 Jan 23 - Who cited this? | PubMed ID: 19167327 | Fulltext

Disruption of Myosin 1e promotes podocyte injury.

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Krendel M, Kim SV, Willinger T, Wang T, Kashgarian M, Flavell RA, and Mooseker MS

Journal of the American Society of Nephrology : JASN 20(1):86-94, 2009 Jan - Who cited this? | PubMed ID: 19005011 | Fulltext

Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease.

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Brochard V, Combadière B, Prigent A, Laouar Y, Perrin A, Beray-Berthat V, Bonduelle O, Alvarez-Fischer D, Callebert J, Launay JM, Duyckaerts C, Flavell RA, Hirsch EC, and Hunot S

The Journal of clinical investigation 119(1):182-92, 2009 Jan - Who cited this? | PubMed ID: 19104149 | Fulltext

Long-term activation of TLR3 by Poly(I:C) induces inflammation and impairs lung function in mice.

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Stowell NC, Seideman J, Raymond HA, Smalley KA, Lamb RJ, Egenolf DD, Bugelski PJ, Murray LA, Marsters PA, Bunting RA, Flavell RA, Alexopoulou L, San Mateo LR, Griswold DE, Sarisky RT, Mbow ML,

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Respiratory research 10:43, 2009 - Who cited this? | PubMed ID: 19486528 | Fulltext

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Papers authored by Flavell RA

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