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Papers authored by Fisher PB

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Ceramide plays a prominent role in MDA-7/IL-24-induced cancer-specific apoptosis.

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Sauane M, Su ZZ, Dash R, Liu X, Norris JS, Sarkar D, Lee SG, Allegood JC, Dent P, Spiegel S, and Fisher PB

Journal of cellular physiology 222(3):546-55, 2010 Mar - Who cited this? | PubMed ID: 19937735 | Fulltext

Chimeric adenoviral vectors incorporating a fiber of human adenovirus 3 efficiently mediate gene transfer into prostate cancer cells.

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Murakami M, Ugai H, Belousova N, Pereboev A, Dent P, Fisher PB, Everts M, and Curiel DT

The Prostate 70(4):362-76, 2010 Mar 1 - Who cited this? | PubMed ID: 19902467 | Fulltext

Cisplatin enhances protein kinase R-like endoplasmic reticulum kinase- and CD95-dependent melanoma differentiation-associated gene-7/interleukin-24-induced killing in ovarian carcinoma cells.

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Yacoub A, Liu R, Park MA, Hamed HA, Dash R, Schramm DN, Sarkar D, Dimitriev IP, Bell JK, Grant S, Farrell NP, Curiel DT, Fisher PB, and Dent P

Molecular pharmacology 77(2):298-310, 2010 Feb - Who cited this? | PubMed ID: 19910452 | Fulltext

PERK-Dependent Regulation of Ceramide Synthase 6 and Thioredoxin Play a Key Role in mda-7/IL-24-Induced Killing of Primary Human Glioblastoma Multiforme Cells.

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Yacoub A, Hamed HA, Allegood J, Mitchell C, Spiegel S, Lesniak MS, Ogretmen B, Dash R, Sarkar D, Broaddus WC, Grant S, Curiel DT, Fisher PB, and Dent P

Cancer research 70(3):1120-9, 2010 Feb 1 - Who cited this? | PubMed ID: 20103619 | Fulltext

Eradication of Therapy-resistant Human Prostate Tumors Using an Ultrasound-guided Site-specific Cancer Terminator Virus Delivery Approach.

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Greco A, Di Benedetto A, Howard CM, Kelly S, Nande R, Dementieva Y, Miranda M, Brunetti A, Salvatore M, Claudio L, Sarkar D, Dent P, Curiel DT, Fisher PB, and Claudio PP

Molecular therapy : the journal of the American Society of Gene Therapy 18(2):295-306, 2010 Feb - Who cited this? | PubMed ID: 19888195 | Fulltext

Astrocyte elevated gene-1: a novel target for human glioma therapy.

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Emdad L, Sarkar D, Lee SG, Su ZZ, Yoo BK, Dash R, Yacoub A, Fuller CE, Shah K, Dent P, Bruce JN, and Fisher PB

Molecular cancer therapeutics 9(1):79-88, 2010 Jan - Who cited this? | PubMed ID: 20053777 | Fulltext

Astrocyte elevated gene-1 (AEG-1) functions as an oncogene and regulates angiogenesis.

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Emdad L, Lee SG, Su ZZ, Jeon HY, Boukerche H, Sarkar D, and Fisher PB

Proceedings of the National Academy of Sciences of the United States of America 106(50):21300-5, 2009 Dec 15 - Who cited this? | PubMed ID: 19940250 | Fulltext

Minting a new class of polo-like-kinase inhibitors.

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Dent P, Curiel DT, Grant S, and Fisher PB

Cancer biology & therapy 8(24):2384-5, 2009 Dec - Who cited this? | PubMed ID: 20009506 | Fulltext

Astrocyte elevated gene-1: far more than just a gene regulated in astrocytes.

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Sarkar D, Emdad L, Lee SG, Yoo BK, Su ZZ, and Fisher PB

Cancer research 69(22):8529-35, 2009 Nov 15 - Who cited this? | PubMed ID: 19903854 | Fulltext

Functions of the cytoplasmic RNA sensors RIG-I and MDA-5: Key regulators of innate immunity.

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Barral PM, Sarkar D, Su ZZ, Barber GN, Desalle R, Racaniello VR, and Fisher PB

Pharmacology & therapeutics 124(2):219-34, 2009 Nov - Who cited this? | PubMed ID: 19615405 | Fulltext

RIG-I is cleaved during picornavirus infection.

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Barral PM, Sarkar D, Fisher PB, and Racaniello VR

Virology 391(2):171-6, 2009 Sep 1 - Who cited this? | PubMed ID: 19628239 | Fulltext

Targeted activation of innate immunity for therapeutic induction of autophagy and apoptosis in melanoma cells.

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Tormo D, Checińska A, Alonso-Curbelo D, Pérez-Guijarro E, Cañón E, Riveiro-Falkenbach E, Calvo TG, Larribere L, Megías D, Mulero F, Piris MA, Dash R, Barral PM, Rodríguez-Peralto JL, Ortiz-Romero P, Tüting T,

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Cancer cell 16(2):103-14, 2009 Aug 4 - Who cited this? | PubMed ID: 19647221 | Fulltext

Identification of genes conferring resistance to 5-fluorouracil.

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Yoo BK, Gredler R, Vozhilla N, Su ZZ, Chen D, Forcier T, Shah K, Saxena U, Hansen U, Fisher PB, and Sarkar D

Proceedings of the National Academy of Sciences of the United States of America 106(31):12938-43, 2009 Aug 4 - Who cited this? | PubMed ID: 19622726 | Fulltext

Astrocyte elevated gene-1 contributes to the pathogenesis of neuroblastoma.

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Lee SG, Jeon HY, Su ZZ, Richards JE, Vozhilla N, Sarkar D, Van Maerken T, and Fisher PB

Oncogene 28(26):2476-84, 2009 Jul 2 - Who cited this? | PubMed ID: 19448665 | Fulltext

Adenovirus-mediated hPNPase(old-35) gene transfer as a therapeutic strategy for neuroblastoma.

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Van Maerken T, Sarkar D, Speleman F, Dent P, Weiss WA, and Fisher PB

Journal of cellular physiology 219(3):707-15, 2009 Jun - Who cited this? | PubMed ID: 19202553 | Fulltext

Synergistic combinations of signaling pathway inhibitors: mechanisms for improved cancer therapy.

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Dent P, Curiel DT, Fisher PB, and Grant S

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 12(3):65-73, 2009 Jun - Who cited this? | PubMed ID: 19395305 | Fulltext

Gene expression analysis of terminal differentiation of human melanoma cells highlights global reductions in cell cycle-associated genes.

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Huynh KM, Kim G, Kim DJ, Yang SJ, Park SM, Yeom YI, Fisher PB, and Kang D

Gene 433(1-2):32-9, 2009 Mar 15 - Who cited this? | PubMed ID: 19100317 | Fulltext

Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression.

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Yoo BK, Emdad L, Su ZZ, Villanueva A, Chiang DY, Mukhopadhyay ND, Mills AS, Waxman S, Fisher RA, Llovet JM, Fisher PB, and Sarkar D

The Journal of clinical investigation 119(3):465-77, 2009 Mar - Who cited this? | PubMed ID: 19221438 | Fulltext

Historical perspective and recent insights into our understanding of the molecular and biochemical basis of the antitumor properties of mda-7/IL-24.

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Emdad L, Lebedeva IV, Su ZZ, Gupta P, Sauane M, Dash R, Grant S, Dent P, Curiel DT, Sarkar D, and Fisher PB

Cancer biology & therapy 8(5):402-11, 2009 Mar - Who cited this? | PubMed ID: 19276652 | Fulltext

PI3K: A rational target for ovarian cancer therapy?.

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Dent P, Grant S, Fisher PB, and Curiel DT

Cancer biology & therapy 8(1):1-4, 2009 Jan - Who cited this? | PubMed ID: 19127116 | Fulltext

Cloning and characterization of SARI (suppressor of AP-1, regulated by IFN).

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Su ZZ, Lee SG, Emdad L, Lebdeva IV, Gupta P, Valerie K, Sarkar D, and Fisher PB

Proceedings of the National Academy of Sciences of the United States of America 105(52):20906-11, 2008 Dec 30 - Who cited this? | PubMed ID: 19074269 | Fulltext

Evolution of MDA-5/RIG-I-dependent innate immunity: independent evolution by domain grafting.

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Sarkar D, Desalle R, and Fisher PB

Proceedings of the National Academy of Sciences of the United States of America 105(44):17040-5, 2008 Nov 4 - Who cited this? | PubMed ID: 18971330 | Fulltext

Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation.

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Park MA, Zhang G, Martin AP, Hamed H, Mitchell C, Hylemon PB, Graf M, Rahmani M, Ryan K, Liu X, Spiegel S, Norris J, Fisher PB, Grant S, and Dent P

Cancer biology & therapy 7(10), 2008 Oct 12 - Who cited this? | PubMed ID: 18787411 | Fulltext

Model cell culture system for defining the molecular and biochemical events mediating terminal differentiation of human melanoma cells.

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Staudt MR, Depass AL, Sarkar D, and Fisher PB

Journal of cellular physiology, 2008 Oct 9 - Who cited this? | PubMed ID: 18844238 | Fulltext

Regulation of autophagy by ceramide-CD95-PERK signaling.

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Park MA, Zhang G, Norris J, Hylemon PB, Fisher PB, Grant S, and Dent P

Autophagy 4(7), 2008 Oct 5 - Who cited this? | PubMed ID: 18719356 | Fulltext

mda-9/Syntenin promotes metastasis in human melanoma cells by activating c-Src.

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Boukerche H, Su ZZ, Prévot C, Sarkar D, and Fisher PB

Proceedings of the National Academy of Sciences of the United States of America, 2008 Oct 2 - Who cited this? | PubMed ID: 18832467 | Fulltext

Multiple cyclin kinase inhibitors promote bile acid-induced apoptosis and autophagy in primary hepatocytes via p53-CD95-dependent signaling.

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Zhang G, Park MA, Mitchell C, Walker T, Hamed H, Studer E, Graf M, Rahmani M, Gupta S, Hylemon PB, Fisher PB, Grant S, and Dent P

The Journal of biological chemistry 283(36):24343, 2008 Sep 5 - Who cited this? | PubMed ID: 18614532 | Fulltext

Mechanism of In vitro Pancreatic Cancer Cell Growth Inhibition by Melanoma Differentiation-Associated Gene-7/Interleukin-24 and Perillyl Alcohol.

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Lebedeva IV, Su ZZ, Vozhilla N, Chatman L, Sarkar D, Dent P, Athar M, and Fisher PB

Cancer research, 2008 Sep 3 - Who cited this? | PubMed ID: 18768668 | Fulltext

Mitogen-activated protein kinase kinase 1/2 inhibitors and 17-allylamino-17-demethoxygeldanamycin synergize to kill human gastrointestinal tumor cells in vitro via suppression of c-FLIP-s levels and activation of CD95.

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Park MA, Zhang G, Mitchell C, Rahmani M, Hamed H, Hagan MP, Yacoub A, Curiel DT, Fisher PB, Grant S, and Dent P

Molecular cancer therapeutics 7(9):2633, 2008 Sep - Who cited this? | PubMed ID: 18790746 | Fulltext

Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation.

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Zhang G, Park MA, Mitchell C, Hamed H, Rahmani M, Martin AP, Curiel DT, Yacoub A, Graf M, Lee R, Roberts JD, Fisher PB, Grant S, and Dent P

Clinical cancer research : an official journal of the American Association for Cancer Research 14(17):5385-99, 2008 Sep 1 - Who cited this? | PubMed ID: 18765530 | Fulltext

Autocrine regulation of mda-7/IL-24 mediates cancer-specific apoptosis.

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Sauane M, Su ZZ, Gupta P, Lebedeva IV, Dent P, Sarkar D, and Fisher PB

Proceedings of the National Academy of Sciences of the United States of America 105(28):9763-8, 2008 Jul 15 - Who cited this? | PubMed ID: 18599461 | Fulltext

Chemoprevention by perillyl alcohol coupled with viral gene therapy reduces pancreatic cancer pathogenesis.

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Lebedeva IV, Su ZZ, Vozhilla N, Chatman L, Sarkar D, Dent P, Athar M, and Fisher PB

Molecular cancer therapeutics 7(7):2042, 2008 Jul - Who cited this? | PubMed ID: 18645014 | Fulltext

Lapatinib resistance in HCT116 cells is mediated by elevated MCL-1 expression, decreased BAK activation, and not by ERBB receptor mutation.

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Martin AP, Miller A, Emdad L, Rahmani M, Walker T, Mitchell C, Hagan MP, Park MA, Yacoub A, Fisher PB, Grant S, and Dent P

Molecular pharmacology, 2008 Jun 10 - Who cited this? | PubMed ID: 18544666 | Fulltext

Targeted combinatorial therapy of non-small cell lung carcinoma using a GST-fusion protein of full-length or truncated MDA-7/IL-24 with Tarceva.

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Gupta P, Emdad L, Lebedeva IV, Sarkar D, Dent P, Curiel DT, Settleman J, and Fisher PB

Journal of cellular physiology 215(3):827-36, 2008 Jun - Who cited this? | PubMed ID: 18270968 | Fulltext

A fiber-modified mesothelin promoter-based conditionally replicating adenovirus for treatment of ovarian cancer.

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Tsuruta Y, Pereboeva L, Breidenbach M, Rein DT, Wang M, Alvarez RD, Siegal GP, Dent P, Fisher PB, and Curiel DT

Clinical cancer research : an official journal of the American Association for Cancer Research 14(11):3582-8, 2008 Jun 1 - Who cited this? | PubMed ID: 18519792 | Fulltext

Secretable chaperone Grp170 enhances therapeutic activity of a novel tumor suppressor, mda-7/IL-24.

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Gao P, Sun X, Chen X, Wang Y, Foster BA, Subjeck J, Fisher PB, and Wang XY

Cancer research 68(10):3890-8, 2008 May 15 - Who cited this? | PubMed ID: 18483274 | Fulltext

Mechanism of ceftriaxone induction of excitatory amino acid transporter-2 expression and glutamate uptake in primary human astrocytes.

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Lee SG, Su ZZ, Emdad L, Gupta P, Sarkar D, Borjabad A, Volsky DJ, and Fisher PB

The Journal of biological chemistry 283(19):13116, 2008 May 9 - Who cited this? | PubMed ID: 18326497 | Fulltext

A cancer terminator virus eradicates both primary and distant human melanomas.

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Sarkar D, Su ZZ, Park ES, Vozhilla N, Dent P, Curiel DT, and Fisher PB

Cancer gene therapy 15(5):293, 2008 May - Who cited this? | PubMed ID: 18323853 | Fulltext

Progression elevated gene-3 promoter (PEG-Prom) confers cancer cell selectivity to human polynucleotide phosphorylase (hPNPase(old-35))-mediated growth suppression.

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Chan I, Lebedeva IV, Su ZZ, Sarkar D, Valerie K, and Fisher PB

Journal of cellular physiology 215(2):401, 2008 May - Who cited this? | PubMed ID: 17960560 | Fulltext

Characterization of infectivity of knob-modified adenoviral vectors in glioma.

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Paul CP, Everts M, Glasgow JN, Dent P, Fisher PB, Ulasov IV, Lesniak MS, Stoff-Khalili MA, Roth JC, Preuss MA, Dirven CM, Lamfers ML, Siegal GP, Zhu ZB, and Curiel DT

Cancer biology & therapy 7(5):786, 2008 May - Who cited this? | PubMed ID: 18756624 | Fulltext

mda-9/Syntenin: more than just a simple adapter protein when it comes to cancer metastasis.

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Sarkar D, Boukerche H, Su ZZ, and Fisher PB

Cancer research 68(9):3087-93, 2008 May 1 - Who cited this? | PubMed ID: 18451132 | Fulltext

PERK-dependent regulation of MDA-7/IL-24-induced autophagy in primary human glioma cells.

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Park MA, Yacoub A, Sarkar D, Emdad L, Rahmani M, Spiegel S, Koumenis C, Graf M, Curiel DT, Grant S, Fisher PB, and Dent P

Autophagy 4(4):513 - Who cited this? | PubMed ID: 18299661 | Fulltext

Apoptotic activity and mechanism of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic-acid and related synthetic triterpenoids in prostate cancer.

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Hyer ML, Shi R, Krajewska M, Meyer C, Lebedeva IV, Fisher PB, and Reed JC

Cancer research 68(8):2927, 2008 Apr 15 - Who cited this? | PubMed ID: 18413762 | Fulltext

OSU-03012 stimulates PKR-like endoplasmic reticulum-dependent increases in 70-kDa heat shock protein expression, attenuating its lethal actions in transformed cells.

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Park MA, Yacoub A, Rahmani M, Zhang G, Hart L, Hagan MP, Calderwood SK, Sherman MY, Koumenis C, Spiegel S, Chen CS, Graf M, Curiel DT, Fisher PB, Grant S, and Dent P

Molecular pharmacology 73(4):1168-84, 2008 Apr - Who cited this? | PubMed ID: 18182481 | Fulltext

Human chorionic gonadotropin (hCG) interacts with lovastatin and ionizing radiation to modulate prostate cancer cell viability in vivo.

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Hamed H, Mitchell C, Park MA, Hanna D, Martin AP, Harrison B, Hawkins W, Curiel DA, Fisher PB, Grant S, Yacoub A, Hagan MP, and Dent P

Cancer biology & therapy 7(4):587-93, 2008 Apr - Who cited this? | PubMed ID: 18379195 | Fulltext

MDA-7/IL-24 Plus Radiation Enhance Survival in Animals with Intracranial Primary Human GBM Tumors.

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Yacoub A, Hamed H, Emdad L, Dos Santos W, Gupta P, Broaddus WC, Ramakrishnan V, Sarkar D, Shah K, Curiel DT, Grant S, Fisher PB, and Dent P

Cancer biology & therapy 7(6), 2008 Mar 19 - Who cited this? | PubMed ID: 18376144 | Fulltext

Phagocytosis of Picornavirus-Infected Cells Induces an RNA-Dependent Antiviral State in Human Dendritic Cells.

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Kramer M, Schulte BM, Toonen LW, Barral PM, Fisher PB, Lanke KH, Galama JM, van Kuppeveld FJ, and Adema GJ

Journal of virology 82(6):2930-7, 2008 Mar - Who cited this? | PubMed ID: 18184700 | Fulltext

Molecular basis of nuclear factor-kappaB activation by astrocyte elevated gene-1.

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Sarkar D, Park ES, Emdad L, Lee SG, Su ZZ, and Fisher PB

Cancer research 68(5):1478-84, 2008 Mar 1 - Who cited this? | PubMed ID: 18316612 | Fulltext

Astrocyte elevated gene-1 activates cell survival pathways through PI3K-Akt signaling.

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Lee SG, Su ZZ, Emdad L, Sarkar D, Franke TF, and Fisher PB

Oncogene 27(8):1114-21, 2008 Feb 14 - Who cited this? | PubMed ID: 17704808 | Fulltext

Caspase-, cathepsin-, and PERK-dependent regulation of MDA-7/IL-24-induced cell killing in primary human glioma cells.

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Yacoub A, Park MA, Gupta P, Rahmani M, Zhang G, Hamed H, Hanna D, Sarkar D, Lebedeva IV, Emdad L, Sauane M, Vozhilla N, Spiegel S, Koumenis C, Graf M, Curiel DT,

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Molecular cancer therapeutics 7(2):297, 2008 Feb - Who cited this? | PubMed ID: 18281515 | Fulltext

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