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Papers authored by Feyen JH

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Discovery and structure-activity relationships of trisubstituted pyrimidines/pyridines as novel calcium-sensing receptor antagonists.

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Yang W, Ruan Z, Wang Y, Van Kirk K, Ma Z, Arey BJ, Cooper CB, Seethala R, Feyen JH, and Dickson JK

Journal of medicinal chemistry 52(4):1204-8, 2009 Feb 26 - Who cited this? | PubMed ID: 19143533 | Fulltext

Interleukin-18 is regulated by parathyroid hormone and is required for its bone anabolic actions.

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Raggatt LJ, Qin L, Tamasi J, Jefcoat SC, Shimizu E, Selvamurugan N, Liew FY, Bevelock L, Feyen JH, and Partridge NC

The Journal of biological chemistry 283(11):6790-8, 2008 Mar 14 - Who cited this? | PubMed ID: 18165223 | Fulltext

Determination of dual effects of parathyroid hormone on skeletal gene expression in vivo by microarray and network analysis.

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Li X, Liu H, Qin L, Tamasi J, Bergenstock M, Shapses S, Feyen JH, Notterman DA, and Partridge NC

The Journal of biological chemistry 282(45):33086, 2007 Nov 9 - Who cited this? | PubMed ID: 17690103 | Fulltext

Discovery of a small molecule antagonist of the parathyroid hormone receptor by using an N-terminal parathyroid hormone peptide probe.

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Carter PH, Liu RQ, Foster WR, Tamasi JA, Tebben AJ, Favata M, Staal A, Cvijic ME, French MH, Dell V, Apanovitch D, Lei M, Zhao Q, Cunningham M, Decicco CP, Trzaskos JM,

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Proceedings of the National Academy of Sciences of the United States of America 104(16):6846-51, 2007 Apr 17 - Who cited this? | PubMed ID: 17428923 | Fulltext

High throughput screening identified a substituted imidazole as a novel RANK pathway-selective osteoclastogenesis inhibitor.

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Chen T, Knapp AC, Wu Y, Huang J, Lynch JS, Dickson JK, Lawrence RM, Feyen JH, and Agler ML

Assay and drug development technologies 4(4):387-96, 2006 Aug - Who cited this? | PubMed ID: 16945012 | Fulltext

A missense mutation in the seven-transmembrane domain of the human Ca2+ receptor converts a negative allosteric modulator into a positive allosteric modulator.

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Hu J, Jiang J, Costanzi S, Thomas C, Yang W, Feyen JH, Jacobson KA, and Spiegel AM

The Journal of biological chemistry 281(30):21558-65, 2006 Jul 28 - Who cited this? | PubMed ID: 16735501 | Fulltext

Synthesis and characterization of 3-arylquinazolinone and 3-arylquinazolinethione derivatives as selective estrogen receptor beta modulators.

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Güngör T, Chen Y, Golla R, Ma Z, Corte JR, Northrop JP, Bin B, Dickson JK, Stouch T, Zhou R, Johnson SE, Seethala R, and Feyen JH

Journal of medicinal chemistry 49(8):2440-55, 2006 Apr 20 - Who cited this? | PubMed ID: 16610787 | Fulltext

Discovery of novel 1-arylmethyl pyrrolidin-2-yl ethanol amines as calcium-sensing receptor antagonists.

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Gavai AV, Vaz RJ, Mikkilineni AB, Roberge JY, Liu Y, Lawrence RM, Corte JR, Yang W, Bednarz M, Dickson JK, Ma Z, Seethala R, and Feyen JH

Bioorganic & medicinal chemistry letters 15(24):5478-82, 2005 Dec 15 - Who cited this? | PubMed ID: 16216508 | Fulltext

Expression profile of osteoblast lineage at defined stages of differentiation.

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Kalajzic I, Staal A, Yang WP, Wu Y, Johnson SE, Feyen JH, Krueger W, Maye P, Yu F, Zhao Y, Kuo L, Gupta RR, Achenie LE, Wang HW, Shin DG, and Rowe DW

The Journal of biological chemistry 280(26):24618, 2005 Jul 1 - Who cited this? | PubMed ID: 15834136 | Fulltext

A novel calcium-sensing receptor antagonist transiently stimulates parathyroid hormone secretion in vivo.

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Arey BJ, Seethala R, Ma Z, Fura A, Morin J, Swartz J, Vyas V, Yang W, Dickson JK, and Feyen JH

Endocrinology 146(4):2015-22, 2005 Apr - Who cited this? | PubMed ID: 15637285 | Fulltext

Discovery and structure-activity relationships of 2-benzylpyrrolidine-substituted aryloxypropanols as calcium-sensing receptor antagonists.

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Yang W, Wang Y, Roberge JY, Ma Z, Liu Y, Michael Lawrence R, Rotella DP, Seethala R, Feyen JH, and Dickson JK

Bioorganic & medicinal chemistry letters 15(4):1225-8, 2005 Feb 15 - Who cited this? | PubMed ID: 15686947 | Fulltext

Amphiregulin is a novel growth factor involved in normal bone development and in the cellular response to parathyroid hormone stimulation.

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Qin L, Tamasi J, Raggatt L, Li X, Feyen JH, Lee DC, Dicicco-Bloom E, and Partridge NC

The Journal of biological chemistry 280(5):3974-81, 2005 Feb 4 - Who cited this? | PubMed ID: 15509566 | Fulltext

Synthesis and structure-activity relationship of 3-arylbenzoxazines as selective estrogen receptor beta agonists.

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Yang W, Wang Y, Ma Z, Golla R, Stouch T, Seethala R, Johnson S, Zhou R, Güngör T, Feyen JH, and Dickson JK

Bioorganic & medicinal chemistry letters 14(9):2327-30, 2004 May 3 - Who cited this? | PubMed ID: 15081034 | Fulltext

Characterization of a new class of selective nonsteroidal progesterone receptor agonists.

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Dong Y, Roberge JY, Wang Z, Wang X, Tamasi J, Dell V, Golla R, Corte JR, Liu Y, Fang T, Anthony MN, Schnur DM, Agler ML, Dickson JK, Lawrence RM, Prack MM,

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Steroids 69(3):201-17, 2004 Mar - Who cited this? | PubMed ID: 15072922 | Fulltext

Mechanisms of action of antiresorptive therapies of postmenopausal osteoporosis.

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Stepan JJ, Alenfeld F, Boivin G, Feyen JH, and Lakatos P

Endocrine regulations 37(4):225-38, 2003 Dec - Who cited this? | PubMed ID: 15106819 | Fulltext

Characterization of bone structure in leptin receptor-deficient Zucker (fa/fa) rats.

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Tamasi JA, Arey BJ, Bertolini DR, and Feyen JH

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 18(9):1605-11, 2003 Sep - Who cited this? | PubMed ID: 12968669 | Fulltext

The ability of statins to inhibit bone resorption is directly related to their inhibitory effect on HMG-CoA reductase activity.

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Staal A, Frith JC, French MH, Swartz J, Güngör T, Harrity TW, Tamasi J, Rogers MJ, and Feyen JH

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 18(1):88-96, 2003 Jan - Who cited this? | PubMed ID: 12510809 | Fulltext

Modulation of the effects of glucocorticoids on collagen synthesis in fetal rat calvariae by insulin-like growth factor binding protein-2.

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Kream BE, Tetradis S, Lafrancis D, Fall PM, Feyen JH, and Raisz LG

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 12(6):889-95, 1997 Jun - Who cited this? | PubMed ID: 9169346 | Fulltext

Establishment and characterization of conditionally immortalized stromal cell lines from a temperature-sensitive T-Ag transgenic mouse.

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Feuerbach D, Loetscher E, Buerki K, Sampath TK, and Feyen JH

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 12(2):179-90, 1997 Feb - Who cited this? | PubMed ID: 9041049 | Fulltext

Expression of the cell-adhesion molecule VCAM-1 by stromal cells is necessary for osteoclastogenesis.

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Feuerbach D and Feyen JH

FEBS letters 402(1):21-4, 1997 Jan 27 - Who cited this? | PubMed ID: 9013850 | Fulltext

Down-regulation of the receptor for parathyroid hormone (PTH) and PTH-related peptide by PTH in primary fetal rat osteoblasts.

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Jongen JW, Willemstein-van Hove EC, van der Meer JM, Bos MP, Jüppner H, Segre GV, Abou-Samra AB, Feyen JH, and Herrmann-Erlee MP

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 11(9):1218-25, 1996 Sep - Who cited this? | PubMed ID: 8864895 | Fulltext

Expression of the parathyroid hormone receptor and correlation with other osteoblastic parameters in fetal rat osteoblasts.

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Bos MP, van der Meer JM, Feyen JH, and Herrmann-Erlee MP

Calcified tissue international 58(2):95-100, 1996 Feb - Who cited this? | PubMed ID: 8998684 | Fulltext

Mycotrienins. A new class of potent inhibitors of osteoclastic bone resorption.

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Feuerbach D, Waelchli R, Fehr T, and Feyen JH

The Journal of biological chemistry 270(43):25949-55, 1995 Oct 27 - Who cited this? | PubMed ID: 7592784 | Fulltext

Down-regulation of the receptor for parathyroid hormone (PTH) and PTH-related peptide by transforming growth factor-beta in primary fetal rat osteoblasts.

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Jongen JW, Willemstein-Van Hove EC, Van der Meer JM, Bos MP, Jüppner H, Segre GV, Abou-Samra AB, Feyen JH, and Herrmann-Erlee MP

Endocrinology 136(8):3260-6, 1995 Aug - Who cited this? | PubMed ID: 7628359 | Fulltext

Down-regulation and differential restoration of cAMP responses upon transient phorbol ester treatment of primary osteoblastic cells.

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Bos MP, Van der Meer JM, Feyen JH, and Herrmann-Erlee MP

Cellular signalling 7(6):617-26, 1995 Aug - Who cited this? | PubMed ID: 8588978 | Fulltext

Regulation of parathyroid hormone-related protein production in a human lung squamous cell carcinoma line.

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Rizzoli R, Feyen JH, Grau G, Wohlwend A, Sappino AP, and Bonjour JP

The Journal of endocrinology 143(2):333-41, 1994 Nov - Who cited this? | PubMed ID: 7829996 | Fulltext

A C-terminally truncated human parathyroid hormone receptor is functional and activates multiple G proteins.

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Schneider H, Feyen JH, and Seuwen K

FEBS letters 351(2):281-5, 1994 Sep 5 - Who cited this? | PubMed ID: 8082781 | Fulltext

Recombinant human leukemia inhibitory factor is mitogenic for human bone-derived osteoblast-like cells.

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Evans DB, Gerber B, and Feyen JH

Biochemical and biophysical research communications 199(1):220-6, 1994 Feb 28 - Who cited this? | PubMed ID: 8123016 | Fulltext

Cloning and functional expression of a human parathyroid hormone receptor.

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Schneider H, Feyen JH, Seuwen K, and Movva NR

European journal of pharmacology 246(2):149-55, 1993 Jul 15 - Who cited this? | PubMed ID: 8397094 | Fulltext

N-terminal truncation of salmon calcitonin leads to calcitonin antagonists. Structure activity relationship of N-terminally truncated salmon calcitonin fragments in vitro and in vivo.

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Feyen JH, Cardinaux F, Gamse R, Bruns C, Azria M, and Trechsel U

Biochemical and biophysical research communications 187(1):8-13, 1992 Aug 31 - Who cited this? | PubMed ID: 1325797 | Fulltext

Recombinant human [Cys281]insulin-like growth factor-binding protein 2 inhibits both basal and insulin-like growth factor I-stimulated proliferation and collagen synthesis in fetal rat calvariae.

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Feyen JH, Evans DB, Binkert C, Heinrich GF, Geisse S, and Kocher HP

The Journal of biological chemistry 266(29):19469-74, 1991 Oct 15 - Who cited this? | PubMed ID: 1717466 | Fulltext

Inhibitory effect of okadaic acid on bone resorption in neonatal mouse calvaria in vitro. Protein dephosphorylation as an important regulatory mechanism in the bone resorption process.

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Feyen JH and Kuntzelmann GM

Biochemical and biophysical research communications 178(2):758-63, 1991 Jul 31 - Who cited this? | PubMed ID: 1650197 | Fulltext

Interleukin-6 is produced by bone and modulated by parathyroid hormone.

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Feyen JH, Elford P, Di Padova FE, and Trechsel U

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 4(4):633-8, 1989 Aug - Who cited this? | PubMed ID: 2816508 | Fulltext

Effects of pertussis toxin on resorption of 19-day-old fetal rat long bones.

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Vargas SJ, Feyen JH, and Raisz LG

Endocrinology 124(5):2159-65, 1989 May - Who cited this? | PubMed ID: 2539969 | Fulltext

Inhibition of bone collagen synthesis by the tumor promoter phorbol 12-myristate 13-acetate.

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Feyen JH, Petersen DN, and Kream BE

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 3(2):173-9, 1988 Apr - Who cited this? | PubMed ID: 3213612 | Fulltext

Prostaglandin production by calvariae from sham operated and oophorectomized rats: effect of 17 beta-estradiol in vivo.

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Feyen JH and Raisz LG

Endocrinology 121(2):819-21, 1987 Aug - Who cited this? | PubMed ID: 3474144 | Fulltext

Cells of bone: proliferation, differentiation, and hormonal regulation.

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Nijweide PJ, Burger EH, and Feyen JH

Physiological reviews 66(4):855-86, 1986 Oct - Who cited this? | PubMed ID: 3532144 | Fulltext

The functional significance of glycosylation of pro-opiomelanocortin in melanotrophs of the mouse pituitary gland.

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Jenks BG, Ederveen AG, Feyen JH, and van Overbeeke AP

The Journal of endocrinology 107(3):365-74, 1985 Dec - Who cited this? | PubMed ID: 2999283 | Fulltext

Effects of exogenous prostanoids on the proliferation of osteoblast-like cells in vitro.

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Feyen JH, Di Bon A, van der Plas A, Löwik CW, and Nijweide PJ

Prostaglandins 30(5):827-40, 1985 Nov - Who cited this? | PubMed ID: 4081065 | Fulltext

Direct effect of parathyroid hormone on the proliferation of osteoblast-like cells; a possible involvement of cyclic AMP.

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van der Plas A, Feyen JH, and Nijweide PJ

Biochemical and biophysical research communications 129(3):918-25, 1985 Jun 28 - Who cited this? | PubMed ID: 2409973 | Fulltext

The fluorimetric determination of the lecithin/sphingomyelin ratio of amniotic fluid after HPLC.

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Gebhardt DO, Soederhuizen W, and Feyen JH

Annals of clinical biochemistry 22 ( Pt 3):321-3, 1985 May - Who cited this? | PubMed ID: 4026193 | Fulltext

Stimulation of arachidonic acid metabolism in primary cultures of osteoblast-like cells by hormones and drugs.

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Feyen JH, van der Wilt G, Moonen P, Di Bon A, and Nijweide PJ

Prostaglandins 28(6):769-81, 1984 Dec - Who cited this? | PubMed ID: 6441189 | Fulltext

Rapid technique for the radiometric assay of phospholipase A2.

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Feyen JH, van Erp PE, and Mier PD

Journal of chromatography 259(2):338-40, 1983 Apr 1 - Who cited this? | PubMed ID: 6853637 | Fulltext

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