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Papers authored by Fearns C

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Nuclear factor kappaB (NF-kappaB) activation primes cells to a pro-inflammatory polarized response to a Toll-like receptor 7 (TLR7) agonist.

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Lee J, Hayashi M, Lo JF, Fearns C, Chu WM, Luo Y, Xiang R, and Chuang TH

The Biochemical journal 421(2):301-10, 2009 Jul 15 - Who cited this? | PubMed ID: 19426145 | Fulltext

Kinome Sirna Screen Identifies SMG-1 as a Negative Regulator of Hypoxia-inducible Factor-1{alpha} in Hypoxia.

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Chen RQ, Yang QK, Chen YL, Oliveira VA, Dalton WS, Fearns C, and Lee JD

The Journal of biological chemistry 284(25):16752-8, 2009 Jun 19 - Who cited this? | PubMed ID: 19406746 | Fulltext

Combined integrin phosphoproteomic analyses and small interfering RNA--based functional screening identify key regulators for cancer cell adhesion and migration.

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Chen Y, Lu B, Yang Q, Fearns C, Yates JR, and Lee JD

Cancer research 69(8):3713-20, 2009 Apr 15 - Who cited this? | PubMed ID: 19351860 | Fulltext

CDC25B mediates rapamycin-induced oncogenic responses in cancer cells.

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Chen RQ, Yang QK, Lu BW, Yi W, Cantin G, Chen YL, Fearns C, Yates JR, and Lee JD

Cancer research 69(6):2663-8, 2009 Mar 15 - Who cited this? | PubMed ID: 19276368 | Fulltext

Protein tyrosine phosphatase PTPN13 negatively regulates Her2/ErbB2 malignant signaling.

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Zhu JH, Chen R, Yi W, Cantin GT, Fearns C, Yang Y, Yates JR, and Lee JD

Oncogene 27(18):2525-31, 2008 Apr 17 - Who cited this? | PubMed ID: 17982484 | Fulltext

MDP-induced interleukin-1beta processing requires Nod2 and CIAS1/NALP3.

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Pan Q, Mathison J, Fearns C, Kravchenko VV, Da Silva Correia J, Hoffman HM, Kobayashi KS, Bertin J, Grant EP, Coyle AJ, Sutterwala FS, Ogura Y, Flavell RA, and Ulevitch RJ

Journal of leukocyte biology 82(1):177-83, 2007 Jul - Who cited this? | PubMed ID: 17403772 | Fulltext

Triad3A regulates ubiquitination and proteasomal degradation of RIP1 following disruption of Hsp90 binding.

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Fearns C, Pan Q, Mathison JC, and Chuang TH

The Journal of biological chemistry 281(45):34592-600, 2006 Nov 10 - Who cited this? | PubMed ID: 16968706 | Fulltext

N-(3-oxo-acyl)homoserine lactones signal cell activation through a mechanism distinct from the canonical pathogen-associated molecular pattern recognition receptor pathways.

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Kravchenko VV, Kaufmann GF, Mathison JC, Scott DA, Katz AZ, Wood MR, Brogan AP, Lehmann M, Mee JM, Iwata K, Pan Q, Fearns C, Knaus UG, Meijler MM, Janda KD, and Ulevitch RJ

The Journal of biological chemistry 281(39):28822-30, 2006 Sep 29 - Who cited this? | PubMed ID: 16893899 | Fulltext

Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4.

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Raetz CR, Garrett TA, Reynolds CM, Shaw WA, Moore JD, Smith DC, Ribeiro AA, Murphy RC, Ulevitch RJ, Fearns C, Reichart D, Glass CK, Benner C, Subramaniam S, Harkewicz R, Bowers-Gentry RC,

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Journal of lipid research 47(5):1097, 2006 May - Who cited this? | PubMed ID: 16479018 | Fulltext

A crucial role of mitochondrial Hsp40 in preventing dilated cardiomyopathy.

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Hayashi M, Imanaka-Yoshida K, Yoshida T, Wood M, Fearns C, Tatake RJ, and Lee JD

Nature medicine 12(1):128-32, 2006 Jan - Who cited this? | PubMed ID: 16327803 | Fulltext

Tid1 negatively regulates the migratory potential of cancer cells by inhibiting the production of interleukin-8.

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Kim SW, Hayashi M, Lo JF, Fearns C, Xiang R, Lazennec G, Yang Y, and Lee JD

Cancer research 65(19):8784, 2005 Oct 1 - Who cited this? | PubMed ID: 16204048 | Fulltext

Big mitogen-activated protein kinase 1/extracellular signal-regulated kinase 5 signaling pathway is essential for tumor-associated angiogenesis.

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Hayashi M, Fearns C, Eliceiri B, Yang Y, and Lee JD

Cancer research 65(17):7699-706, 2005 Sep 1 - Who cited this? | PubMed ID: 16140937 | Fulltext

Tid1 is required for T cell transition from double-negative 3 to double-positive stages.

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Lo JF, Zhou H, Fearns C, Reisfeld RA, Yang Y, and Lee JD

Journal of immunology (Baltimore, Md. : 1950) 174(10):6105, 2005 May 15 - Who cited this? | PubMed ID: 15879105 | Fulltext

Tid1, the human homologue of a Drosophila tumor suppressor, reduces the malignant activity of ErbB-2 in carcinoma cells.

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Kim SW, Chao TH, Xiang R, Lo JF, Campbell MJ, Fearns C, and Lee JD

Cancer research 64(21):7732, 2004 Nov 1 - Who cited this? | PubMed ID: 15520177 | Fulltext

Tid1, a cochaperone of the heat shock 70 protein and the mammalian counterpart of the Drosophila tumor suppressor l(2)tid, is critical for early embryonic development and cell survival.

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Lo JF, Hayashi M, Woo-Kim S, Tian B, Huang JF, Fearns C, Takayama S, Zapata JM, Yang Y, and Lee JD

Molecular and cellular biology 24(6):2226-36, 2004 Mar - Who cited this? | PubMed ID: 14993262 | Fulltext

MKK3 mitogen-activated protein kinase pathway mediates carbon monoxide-induced protection against oxidant-induced lung injury.

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Otterbein LE, Otterbein SL, Ifedigbo E, Liu F, Morse DE, Fearns C, Ulevitch RJ, Knickelbein R, Flavell RA, and Choi AM

The American journal of pathology 163(6):2555-63, 2003 Dec - Who cited this? | PubMed ID: 14633627 | Fulltext

Expression and role of CD14 in mice sensitized to lipopolysaccharide by Propionibacterium acnes.

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Merlin T, Woelky-Bruggmann R, Fearns C, Freudenberg M, and Landmann R

European journal of immunology 32(3):761-72, 2002 Mar - Who cited this? | PubMed ID: 11870620 | Fulltext

Inhibition of the tissue factor-thrombin pathway limits infarct size after myocardial ischemia-reperfusion injury by reducing inflammation.

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Erlich JH, Boyle EM, Labriola J, Kovacich JC, Santucci RA, Fearns C, Morgan EN, Yun W, Luther T, Kojikawa O, Martin TR, Pohlman TH, Verrier ED, and Mackman N

The American journal of pathology 157(6):1849-62, 2000 Dec - Who cited this? | PubMed ID: 11106558 | Fulltext

Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest.

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Wang X, McGowan CH, Zhao M, He L, Downey JS, Fearns C, Wang Y, Huang S, and Han J

Molecular and cellular biology 20(13):4543-52, 2000 Jul - Who cited this? | PubMed ID: 10848581 | Fulltext

Coordinate activation of endogenous p38alpha, beta, gamma, and delta by inflammatory stimuli.

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Fearns C, Kline L, Gram H, Di Padova F, Zurini M, Han J, and Ulevitch RJ

Journal of leukocyte biology 67(5):705-11, 2000 May - Who cited this? | PubMed ID: 10811012 | Fulltext

Tissue factor is required for uterine hemostasis and maintenance of the placental labyrinth during gestation.

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Erlich J, Parry GC, Fearns C, Muller M, Carmeliet P, Luther T, and Mackman N

Proceedings of the National Academy of Sciences of the United States of America 96(14):8138, 1999 Jul 6 - Who cited this? | PubMed ID: 10393961 | Fulltext

Lipopolysaccharide induction of tissue factor expression in rabbits.

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Erlich J, Fearns C, Mathison J, Ulevitch RJ, and Mackman N

Infection and immunity 67(5):2540-6, 1999 May - Who cited this? | PubMed ID: 10225918 | Fulltext

The origin and function of soluble CD14 in experimental bacterial meningitis.

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Cauwels A, Frei K, Sansano S, Fearns C, Ulevitch R, Zimmerli W, and Landmann R

Journal of immunology (Baltimore, Md. : 1950) 162(8):4762-72, 1999 Apr 15 - Who cited this? | PubMed ID: 10202018 | Fulltext

Tissue distribution and regulation of murine von Willebrand factor gene expression in vivo.

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Yamamoto K, de Waard V, Fearns C, and Loskutoff DJ

Blood 92(8):2791-801, 1998 Oct 15 - Who cited this? | PubMed ID: 9763564 | Fulltext

Effect of recombinant interleukin-1beta on murine CD14 gene expression in vivo.

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Fearns C and Ulevitch RJ

Shock (Augusta, Ga.) 9(3):157-63, 1998 Mar - Who cited this? | PubMed ID: 9525321 | Fulltext

Role of tumor necrosis factor alpha in induction of murine CD14 gene expression by lipopolysaccharide.

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Fearns C and Loskutoff DJ

Infection and immunity 65(11):4822-31, 1997 Nov - Who cited this? | PubMed ID: 9353071 | Fulltext

Induction of plasminogen activator inhibitor 1 gene expression in murine liver by lipopolysaccharide. Cellular localization and role of endogenous tumor necrosis factor-alpha.

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Fearns C and Loskutoff DJ

The American journal of pathology 150(2):579-90, 1997 Feb - Who cited this? | PubMed ID: 9033272 | Fulltext

Murine CD14 gene expression in vivo: extramyeloid synthesis and regulation by lipopolysaccharide.

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Fearns C, Kravchenko VV, Ulevitch RJ, and Loskutoff DJ

The Journal of experimental medicine 181(3):857-66, 1995 Mar 1 - Who cited this? | PubMed ID: 7532683 | Fulltext

Unusual growth characteristics of human melanoma xenografts in the nude mouse: a model for desmoplasia, dormancy and progression.

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Gartner MF, Fearns C, Wilson EL, Campbell JA, and Dowdle EB

British journal of cancer 65(4):487-90, 1992 Apr - Who cited this? | PubMed ID: 1562456 | Fulltext

The desmoplastic response: induction of collagen synthesis by melanoma cells in vitro.

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Fearns C and Dowdle EB

International journal of cancer. Journal international du cancer 50(4):621-7, 1992 Feb 20 - Who cited this? | PubMed ID: 1537627 | Fulltext

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