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Papers authored by Faragher RG

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Microarray analysis of senescent vascular smooth muscle cells: A link to atherosclerosis and vascular calcification.

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Burton DG, Giles PJ, Sheerin AN, Smith SK, Lawton JJ, Ostler EL, Rhys-Williams W, Kipling D, and Faragher RG

Experimental gerontology 44(10):659-65, 2009 Oct - Who cited this? | PubMed ID: 19631729 | Fulltext

The in vitro kinetics of senescence of Fischer 344 rat embryo fibroblasts.

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Faragher RG and Kill IR

Biogerontology 10(3):285-9, 2009 Jun - Who cited this? | PubMed ID: 19115081 | Fulltext

A transcriptomic analysis of the EK1.Br strain of human fibroblastoid keratocytes: the effects of growth, quiescence and senescence.

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Kipling D, Jones DL, Smith SK, Giles PJ, Jennert-Burston K, Ibrahim B, Sheerin AN, Evans AJ, Rhys-Willams W, and Faragher RG

Experimental eye research 88(2):277-85, 2009 Feb - Who cited this? | PubMed ID: 19087878 | Fulltext

What can we learn from the cross-species biology of ageing?.

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Faragher RG

SEB experimental biology series 62:1-15, 2009 - Who cited this? | PubMed ID: 19418989 | Fulltext

Can we intervene in human ageing?.

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Faragher RG, Sheerin AN, and Ostler EL

Expert reviews in molecular medicine 11:e27, 2009 - Who cited this? | PubMed ID: 19732491 | Fulltext

Cell divisions and mammalian aging: integrative biology insights from genes that regulate longevity.

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de Magalhães JP and Faragher RG

BioEssays : news and reviews in molecular, cellular and developmental biology 30(6):567-78, 2008 Jun - Who cited this? | PubMed ID: 18478536 | Fulltext

Cyclin d1 overexpression permits the reproducible detection of senescent human vascular smooth muscle cells.

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Burton DG, Sheerin AN, Ostler EL, Smith K, Giles PJ, Lowe J, Rhys-Williams W, Kipling DG, and Faragher RG

Annals of the New York Academy of Sciences 1119:20-31, 2007 Dec - Who cited this? | PubMed ID: 18056951 | Fulltext

From old organisms to new molecules: integrative biology and therapeutic targets in accelerated human ageing.

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Cox LS and Faragher RG

Cellular and molecular life sciences : CMLS 64(19-20):2620-41, 2007 Oct - Who cited this? | PubMed ID: 17660942 | Fulltext

A novel population of repair cells identified in the stroma of the human cornea.

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Thill M, Schlagner K, Altenähr S, Ergün S, Faragher RG, Bednarz J, Vohwinkel G, Rogiers X, Hossfeld DK, Richard G, and Gehling UM

Stem cells and development 16(5):733-46, 2007 Oct - Who cited this? | PubMed ID: 17999595 | Fulltext

alpha-Lipoic acid and glutathione protect against the prooxidant activity of SOD/catalase mimetic manganese salen derivatives.

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Fucassi F, Lowe JE, Pavey KD, Shah S, Faragher RG, Green MH, Paul F, O'Hare D, and Cragg PJ

Journal of inorganic biochemistry 101(2):225-32, 2007 Feb - Who cited this? | PubMed ID: 17095093 | Fulltext

Hydroxyapatite promotes superior keratocyte adhesion and proliferation in comparison with current keratoprosthesis skirt materials.

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Mehta JS, Futter CE, Sandeman SR, Faragher RG, Hing KA, Tanner KE, and Allan BD

The British journal of ophthalmology 89(10):1356-62, 2005 Oct - Who cited this? | PubMed ID: 16170132 | Fulltext

Bridging the gap: ageing, pharmacokinetics and pharmacodynamics.

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Burton DG, Allen MC, Bird JL, and Faragher RG

The Journal of pharmacy and pharmacology 57(6):671-9, 2005 Jun - Who cited this? | PubMed ID: 15969921 | Fulltext

Replicative senescence in sheep fibroblasts is a p53 dependent process.

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Davis T, Skinner JW, Faragher RG, Jones CJ, and Kipling D

Experimental gerontology 40(1-2):17-26, 2005 - Who cited this? | PubMed ID: 15664728 | Fulltext

Molecular cytogenetic insights into the ageing syndrome Hutchinson-Gilford Progeria (HGPS).

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Corso C, Parry EM, Faragher RG, Seager A, Green MH, and Parry JM

Cytogenetic and genome research 111(1):27-33, 2005 - Who cited this? | PubMed ID: 16093717 | Fulltext

The development of in vitro biocompatibility tests for the evaluation of intraocular biomaterials.

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Lloyd AW, Dropcova S, Faragher RG, Gard PR, Hanlon GW, Mikhalovsky SV, Olliff CJ, Denyer SP, Letko E, and Filipec M

Journal of materials science. Materials in medicine 10(10/11):621 - Who cited this? | PubMed ID: 15347976 | Fulltext

What can progeroid syndromes tell us about human aging?.

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Kipling D, Davis T, Ostler EL, and Faragher RG

Science (New York, N.Y.) 305(5689):1426-31, 2004 Sep 3 - Who cited this? | PubMed ID: 15353794 | Fulltext

Camptothecin sensitivity in Werner syndrome fibroblasts as assessed by the COMET technique.

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Lowe J, Sheerin A, Jennert-Burston K, Burton D, Ostler EL, Bird J, Green MH, and Faragher RG

Annals of the New York Academy of Sciences 1019:256-9, 2004 Jun - Who cited this? | PubMed ID: 15247024 | Fulltext

Investigation of the signaling pathways involved in the proliferative life span barriers in werner syndrome fibroblasts.

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Davis T, Faragher RG, Jones CJ, and Kipling D

Annals of the New York Academy of Sciences 1019:274-7, 2004 Jun - Who cited this? | PubMed ID: 15247028 | Fulltext

Fibroblast clones from patients with Hutchinson-Gilford progeria can senesce despite the presence of telomerase.

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Wallis CV, Sheerin AN, Green MH, Jones CJ, Kipling D, and Faragher RG

Experimental gerontology 39(4):461-7, 2004 Apr - Who cited this? | PubMed ID: 15050279 | Fulltext

Analysis of cytokine-induced NO-dependent apoptosis using RNA interference or inhibition by 1400W.

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Beeharry N, Chambers JA, Faragher RG, Garnett KE, and Green IC

Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 10(2):112-8, 2004 Mar - Who cited this? | PubMed ID: 15135364 | Fulltext

Telomere-based proliferative lifespan barriers in Werner-syndrome fibroblasts involve both p53-dependent and p53-independent mechanisms.

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Davis T, Singhrao SK, Wyllie FS, Haughton MF, Smith PJ, Wiltshire M, Wynford-Thomas D, Jones CJ, Faragher RG, and Kipling D

Journal of cell science 116(Pt 7):1349-57, 2003 Apr 1 - Who cited this? | PubMed ID: 12615976 | Fulltext

Can we say that senescent cells cause ageing?.

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Bird J, Ostler EL, and Faragher RG

Experimental gerontology 38(11-12):1319-26, 2003 - Who cited this? | PubMed ID: 14698811 | Fulltext

A model for the phenotypic presentation of Werner's syndrome.

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Ostler EL, Wallis CV, Sheerin AN, and Faragher RG

Experimental gerontology 37(2-3):285-92, 2002 - Who cited this? | PubMed ID: 11772514 | Fulltext

Ocular biomaterials and implants.

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Lloyd AW, Faragher RG, and Denyer SP

Biomaterials 22(8):769-85, 2001 Apr - Who cited this? | PubMed ID: 11246945 | Fulltext

Does MMP-2 expression and secretion change with increasing serial passage of keratocytes in culture?.

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Sandeman SR, Faragher RG, Allen MC, Liu C, and Lloyd AW

Mechanisms of ageing and development 122(2):157-67, 2001 Feb - Who cited this? | PubMed ID: 11166355 | Fulltext

Ageing and the nervous system: insights from studies on invertebrates.

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Yeoman MS and Faragher RG

Biogerontology 2(2):85-97, 2001 - Who cited this? | PubMed ID: 11708380 | Fulltext

Werner's syndrome T lymphocytes display a normal in vitro life-span.

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James SE, Faragher RG, Burke JF, Shall S, and Mayne LV

Mechanisms of ageing and development 121(1-3):139-49, 2000 Dec 20 - Who cited this? | PubMed ID: 11164468 | Fulltext

A cell kinetic analysis of human umbilical vein endothelial cells.

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Kalashnik L, Bridgeman CJ, King AR, Francis SE, Mikhalovsky S, Wallis C, Denyer SP, Crossman D, and Faragher RG

Mechanisms of ageing and development 120(1-3):23-32, 2000 Dec 1 - Who cited this? | PubMed ID: 11087901 | Fulltext

Human keratocyte migration into collagen gels declines with in vitro ageing.

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Sandeman SR, Allen MC, Liu C, Faragher RG, and Lloyd AW

Mechanisms of ageing and development 119(3):149-57, 2000 Nov 15 - Who cited this? | PubMed ID: 11080534 | Fulltext

Novel materials to enhance keratoprosthesis integration.

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Sandeman SR, Faragher RG, Allen MC, Liu C, and Lloyd AW

The British journal of ophthalmology 84(6):640-4, 2000 Jun - Who cited this? | PubMed ID: 10837393 | Fulltext

Cell senescence and human aging: where's the link?.

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Faragher RG

Biochemical Society transactions 28(2):221-6, 2000 Feb - Who cited this? | PubMed ID: 10816132 | Fulltext

Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts.

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Wyllie FS, Jones CJ, Skinner JW, Haughton MF, Wallis C, Wynford-Thomas D, Faragher RG, and Kipling D

Nature genetics 24(1):16-7, 2000 Jan - Who cited this? | PubMed ID: 10615119 | Fulltext

Telomerase and the cellular lifespan: implications of the aging process.

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Ostler EL, Wallis CV, Aboalchamat B, and Faragher RG

Journal of pediatric endocrinology & metabolism : JPEM 13 Suppl 6:1467-76, 2000 - Who cited this? | PubMed ID: 11202223 | Fulltext

Assessing the in vitro cell based ocular compatibility of contact lens materials.

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Lloyd AW, Faragher RG, Wassall M, Rhys-Williams W, Wong L, Hughes JE, and Hanlon GW

Contact lens & anterior eye : the journal of the British Contact Lens Association 23(4):119-23, 2000 - Who cited this? | PubMed ID: 16303442 | Fulltext

Telomere-dependent senescence.

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Kipling D, Wynford-Thomas D, Jones CJ, Akbar A, Aspinall R, Bacchetti S, Blasco MA, Broccoli D, DePinho RA, Edwards DR, Effros RB, Harley CB, Lansdorp PM, Linskens MH, Prowse KR, Newbold RF,

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Nature biotechnology 17(4):313-4, 1999 Apr - Who cited this? | PubMed ID: 10207859 | Fulltext

Telomeres. Ageing hard or hardly ageing?.

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Kipling D and Faragher RG

Nature 398(6724):191, 193, 1999 Mar 18 - Who cited this? | PubMed ID: 10094039 | Fulltext

A standard strain of human ocular keratocytes.

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Dropcova S, Denyer SP, Lloyd AW, Gard PR, Hanlon GW, Mikhalovsky SV, Sandeman S, Olliff CJ, and Faragher RG

Ophthalmic research 31(1):33-41, 1999 - Who cited this? | PubMed ID: 9831820 | Fulltext

How might replicative senescence contribute to human ageing?.

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Faragher RG and Kipling D

BioEssays : news and reviews in molecular, cellular and developmental biology 20(12):985, 1998 Dec - Who cited this? | PubMed ID: 10048298 | Fulltext

Telomerase and cellular lifespan: ending the debate?.

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Faragher RG, Jones CJ, and Kipling D

Nature biotechnology 16(8):701-2, 1998 Aug - Who cited this? | PubMed ID: 9702755 | Fulltext

The kinetics of senescence in retinal pigmented epithelial cells: a test for the telomere hypothesis of ageing?.

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Rawes V, Kipling D, Kill IR, and Faragher RG

Biochemistry. Biokhimiia 62(11):1291-5, 1997 Nov - Who cited this? | PubMed ID: 9467853 | Fulltext

Different kinetics of senescence in human fibroblasts and peritoneal mesothelial cells.

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Thomas E, al-Baker E, Dropcova S, Denyer S, Ostad N, Lloyd A, Kill IR, and Faragher RG

Experimental cell research 236(1):355-8, 1997 Oct 10 - Who cited this? | PubMed ID: 9344618 | Fulltext

Aging and the cornea.

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Faragher RG, Mulholland B, Tuft SJ, Sandeman S, and Khaw PT

The British journal of ophthalmology 81(10):814-7, 1997 Oct - Who cited this? | PubMed ID: 9486017 | Fulltext

Progeroid syndromes: probing the molecular basis of aging?.

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Kipling D and Faragher RG

Molecular pathology : MP 50(5):234-41, 1997 Oct - Who cited this? | PubMed ID: 9497912 | Fulltext

Cycling Werner's syndrome fibroblasts display calcium-dependent potassium currents.

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Faragher RG, Hardy SP, Davis T, Dropcova S, and Allen MC

Experimental cell research 231(1):119-22, 1997 Feb 25 - Who cited this? | PubMed ID: 9056418 | Fulltext

The expression of proliferation-dependent antigens during the lifespan of normal and progeroid human fibroblasts in culture.

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Kill IR, Faragher RG, Lawrence K, and Shall S

Journal of cell science 107 ( Pt 2):571-9, 1994 Feb - Who cited this? | PubMed ID: 7911472 | Fulltext

The gene responsible for Werner syndrome may be a cell division "counting" gene.

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Faragher RG, Kill IR, Hunter JA, Pope FM, Tannock C, and Shall S

Proceedings of the National Academy of Sciences of the United States of America 90(24):12030-4, 1993 Dec 15 - Who cited this? | PubMed ID: 8265666 | Fulltext

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