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Papers authored by Ernest CS

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Pharmacokinetics and pharmacodynamics of prasugrel in subjects with moderate liver disease.

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Small DS, Farid NA, Li YG, Ernest CS, Winters KJ, Salazar DE, and Payne CD

Journal of clinical pharmacy and therapeutics 34(5):575-83, 2009 Oct - Who cited this? | PubMed ID: 19744013 | Fulltext

Prasugrel pharmacokinetics and pharmacodynamics in subjects with moderate renal impairment and end-stage renal disease.

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Small DS, Wrishko RE, Ernest CS, Ni L, Winters KJ, Farid NA, Li YG, Brandt JT, Salazar DE, Borel AG, Kles KA, and Payne CD

Journal of clinical pharmacy and therapeutics 34(5):585-94, 2009 Oct - Who cited this? | PubMed ID: 19744014 | Fulltext

Population Pharmacokinetic Analyses to Evaluate the Influence of Intrinsic and Extrinsic Factors on Exposure of Prasugrel Active Metabolite in TRITON-TIMI 38.

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Wrishko RE, Ernest CS, Small DS, Li YG, Weerakkody GJ, Riesmeyer JR, Macias WL, Rohatagi S, Salazar DE, Antman EM, Wiviott SD, Braunwald E, and Ni L

Journal of clinical pharmacology 49(8):984-98, 2009 Aug - Who cited this? | PubMed ID: 19546250 | Fulltext

Prediction of prasugrel active metabolite concentrations from 2 downstream inactive metabolite concentrations using multilinear regression analysis.

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Ernest CS, Heathman MA, and Wrishko RE

Journal of clinical pharmacology 49(8):973-83, 2009 Aug - Who cited this? | PubMed ID: 19602721 | Fulltext

Inhibition of platelet aggregation with prasugrel and clopidogrel: an integrated analysis in 846 subjects.

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Li YG, Ni L, Brandt JT, Small DS, Payne CD, Ernest CS, Rohatagi S, Farid NA, Jakubowski JA, and Winters KJ

Platelets 20(5):316-27, 2009 Aug - Who cited this? | PubMed ID: 19637095 | Fulltext

Effect of Age on the Pharmacokinetics and Pharmacodynamics of Prasugrel during Multiple Dosing: An Open-Label, Single-Sequence, Clinical Trial.

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Small DS, Wrishko RE, Ernest CS, Ni L, Winters KJ, Farid NA, Li YG, Salazar DE, and Payne CD

Drugs & aging 26(9):781-90, 2009 - Who cited this? | PubMed ID: 19728751 | Fulltext

Effect of atorvastatin on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel in healthy subjects.

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Farid NA, Small DS, Payne CD, Jakubowski JA, Brandt JT, Li YG, Ernest CS, Salazar DE, Konkoy CS, and Winters KJ

Pharmacotherapy 28(12):1483-94, 2008 Dec - Who cited this? | PubMed ID: 19025429 | Fulltext

Population pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel in aspirin-treated patients with stable coronary artery disease.

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Ernest CS, Small DS, Rohatagi S, Salazar DE, Wallentin L, Winters KJ, and Wrishko RE

Journal of pharmacokinetics and pharmacodynamics 35(6):593-618, 2008 Dec - Who cited this? | PubMed ID: 19023649 | Fulltext

Effect of ranitidine on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel.

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Small DS, Farid NA, Li YG, Ernest CS, Payne CD, Salazar DE, and Winters KJ

Current medical research and opinion 24(8):2251-7, 2008 Aug - Who cited this? | PubMed ID: 18786302 | Fulltext

Living alone predicts 30-day hospital readmission after coronary artery bypass graft surgery.

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Murphy BM, Elliott PC, Le Grande MR, Higgins RO, Ernest CS, Goble AJ, Tatoulis J, and Worcester MU

European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 15(2):210-5, 2008 Apr - Who cited this? | PubMed ID: 18391650 | Fulltext

Prasugrel, a New Thienopyridine Antiplatelet Drug, Weakly Inhibits Cytochrome P450 2B6 in Humans.

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Farid NA, Payne CD, Ernest CS, Li YG, Winters KJ, Salazar DE, and Small DS

Journal of clinical pharmacology 48(1):53-9, 2008 Jan - Who cited this? | PubMed ID: 18094219 | Fulltext

Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel.

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Brandt JT, Close SL, Iturria SJ, Payne CD, Farid NA, Ernest CS, Lachno DR, Salazar D, and Winters KJ

Journal of thrombosis and haemostasis : JTH 5(12):2429-36, 2007 Dec - Who cited this? | PubMed ID: 17900275 | Fulltext

Increased active metabolite formation explains the greater platelet inhibition with prasugrel compared to high-dose clopidogrel.

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Payne CD, Li YG, Small DS, Ernest CS, Farid NA, Jakubowski JA, Brandt JT, Salazar DE, and Winters KJ

Journal of cardiovascular pharmacology 50(5):555-62, 2007 Nov - Who cited this? | PubMed ID: 18030066 | Fulltext

Cytochrome P450 3A inhibition by ketoconazole affects prasugrel and clopidogrel pharmacokinetics and pharmacodynamics differently.

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Farid NA, Payne CD, Small DS, Winters KJ, Ernest CS, Brandt JT, Darstein C, Jakubowski JA, and Salazar DE

Clinical pharmacology and therapeutics 81(5):735-41, 2007 May - Who cited this? | PubMed ID: 17361128 | Fulltext

Predictors of cognitive function in candidates for coronary artery bypass graft surgery.

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Ernest CS, Elliott PC, Murphy BM, Le Grande MR, Goble AJ, Higgins RO, Worcester MU, and Tatoulis J

Journal of the International Neuropsychological Society : JINS 13(2):257-66, 2007 Mar - Who cited this? | PubMed ID: 17286883 | Fulltext

Cognitive function in candidates for coronary artery bypass graft surgery.

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Ernest CS, Murphy BM, Worcester MU, Higgins RO, Elliott PC, Goble AJ, Le Grande MR, Genardini N, and Tatoulis J

The Annals of thoracic surgery 82(3):812-8, 2006 Sep - Who cited this? | PubMed ID: 16928490 | Fulltext

Stochastic prediction of CYP3A-mediated inhibition of midazolam clearance by ketoconazole.

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Chien JY, Lucksiri A, Ernest CS, Gorski JC, Wrighton SA, and Hall SD

Drug metabolism and disposition: the biological fate of chemicals 34(7):1208, 2006 Jul - Who cited this? | PubMed ID: 16611859 | Fulltext

Neurocognitive outcomes in off-pump versus on-pump bypass surgery: a randomized controlled trial.

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Ernest CS, Worcester MU, Tatoulis J, Elliott PC, Murphy BM, Higgins RO, Le Grande MR, and Goble AJ

The Annals of thoracic surgery 81(6):2105-14, 2006 Jun - Who cited this? | PubMed ID: 16731138 | Fulltext

Exenatide: effect of injection time on postprandial glucose in patients with Type 2 diabetes.

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Linnebjerg H, Kothare PA, Skrivanek Z, de la Peña A, Atkins M, Ernest CS, and Trautmann ME

Diabetic medicine : a journal of the British Diabetic Association 23(3):240-5, 2006 Mar - Who cited this? | PubMed ID: 16492205 | Fulltext

Health related quality of life trajectories and predictors following coronary artery bypass surgery.

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Le Grande MR, Elliott PC, Murphy BM, Worcester MU, Higgins RO, Ernest CS, and Goble AJ

Health and quality of life outcomes 4:49, 2006 - Who cited this? | PubMed ID: 16904010 | Fulltext

Dose response of inhaled dry-powder insulin and dose equivalence to subcutaneous insulin lispro.

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Rave KM, Nosek L, de la Peña A, Seger M, Ernest CS, Heinemann L, Batycky RP, and Muchmore DB

Diabetes care 28(10):2400-5, 2005 Oct - Who cited this? | PubMed ID: 16186270 | Fulltext

Mechanism-based inactivation of CYP3A by HIV protease inhibitors.

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Ernest CS, Hall SD, and Jones DR

The Journal of pharmacology and experimental therapeutics 312(2):583-91, 2005 Feb - Who cited this? | PubMed ID: 15523003 | Fulltext

Inhaled micronized crystalline human insulin using a dry powder inhaler: dose-response and time-action profiles.

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Rave K, Nosek L, Heinemann L, Gonzales C, Ernest CS, Chien J, and Muchmore D

Diabetic medicine : a journal of the British Diabetic Association 21(7):763-8, 2004 Jul - Who cited this? | PubMed ID: 15209771 | Fulltext

Effect of potent CYP2D6 inhibition by paroxetine on atomoxetine pharmacokinetics.

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Belle DJ, Ernest CS, Sauer JM, Smith BP, Thomasson HR, and Witcher JW

Journal of clinical pharmacology 42(11):1219-27, 2002 Nov - Who cited this? | PubMed ID: 12412820 | Fulltext

Phase I and pharmacokinetic study of LY309887: a specific inhibitor of purine biosynthesis.

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Budman DR, Johnson R, Barile B, Bowsher RR, Vinciguerra V, Allen SL, Kolitz J, Ernest CS, Kreis W, Zervos P, and Walling J

Cancer chemotherapy and pharmacology 47(6):525-31, 2001 Jun - Who cited this? | PubMed ID: 11459206 | Fulltext

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