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Papers authored by Erdos MR

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Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.

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Saxena R, Hivert MF, Langenberg C, Tanaka T, Pankow JS, Vollenweider P, Lyssenko V, Bouatia-Naji N, Dupuis J, Jackson AU, Kao WH, Li M, Glazer NL, Manning AK, Luan J, Stringham HM,

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Nature genetics 42(2):142-8, 2010 Feb - Who cited this? | PubMed ID: 20081857 | Fulltext

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.

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Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Mägi R, Morris AP, Randall J, Johnson T, Elliott P,

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Nature genetics 42(2):105-16, 2010 Feb - Who cited this? | PubMed ID: 20081858 | Fulltext

Parental origin of sequence variants associated with complex diseases.

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Kong A, Steinthorsdottir V, Masson G, Thorleifsson G, Sulem P, Besenbacher S, Jonasdottir A, Sigurdsson A, Kristinsson KT, Jonasdottir A, Frigge ML, Gylfason A, Olason PI, Gudjonsson SA, Sverrisson S, Stacey SN,

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Nature 462(7275):868-74, 2009 Dec 17 - Who cited this? | PubMed ID: 20016592 | Fulltext

Tissue-specific alternative splicing of TCF7L2.

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Prokunina-Olsson L, Welch C, Hansson O, Adhikari N, Scott LJ, Usher N, Tong M, Sprau A, Swift A, Bonnycastle LL, Erdos MR, He Z, Saxena R, Harmon B, Kotova O, Hoffman EP,

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Human molecular genetics 18(20):3795-804, 2009 Oct 15 - Who cited this? | PubMed ID: 19602480 | Fulltext

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.

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Lindgren CM, Heid IM, Randall JC, Lamina C, Steinthorsdottir V, Qi L, Speliotes EK, Thorleifsson G, Willer CJ, Herrera BM, Jackson AU, Lim N, Scheet P, Soranzo N, Amin N, Aulchenko YS,

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PLoS genetics 5(6):e1000508, 2009 Jun - Who cited this? | PubMed ID: 19557161 | Fulltext

Variants in MTNR1B influence fasting glucose levels.

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Prokopenko I, Langenberg C, Florez JC, Saxena R, Soranzo N, Thorleifsson G, Loos RJ, Manning AK, Jackson AU, Aulchenko Y, Potter SC, Erdos MR, Sanna S, Hottenga JJ, Wheeler E, Kaakinen M,

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Nature genetics 41(1):77-81, 2009 Jan - Who cited this? | PubMed ID: 19060907 | Fulltext

Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion.

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Lyssenko V, Nagorny CL, Erdos MR, Wierup N, Jonsson A, Spégel P, Bugliani M, Saxena R, Fex M, Pulizzi N, Isomaa B, Tuomi T, Nilsson P, Kuusisto J, Tuomilehto J, Boehnke M,

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Nature genetics 41(1):82-8, 2009 Jan - Who cited this? | PubMed ID: 19060908 | Fulltext

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.

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Willer CJ, Speliotes EK, Loos RJ, Li S, Lindgren CM, Heid IM, Berndt SI, Elliott AL, Jackson AU, Lamina C, Lettre G, Lim N, Lyon HN, McCarroll SA, Papadakis K, Qi L,

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Nature genetics 41(1):25-34, 2009 Jan - Who cited this? | PubMed ID: 19079261 | Fulltext

A farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse model.

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Capell BC, Olive M, Erdos MR, Cao K, Faddah DA, Tavarez UL, Conneely KN, Qu X, San H, Ganesh SK, Chen X, Avallone H, Kolodgie FD, Virmani R, Nabel EG, and Collins FS

Proceedings of the National Academy of Sciences of the United States of America, 2008 Oct 6 - Who cited this? | PubMed ID: 18838683 | Fulltext

Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels.

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Chen WM, Erdos MR, Jackson AU, Saxena R, Sanna S, Silver KD, Timpson NJ, Hansen T, Orrù M, Grazia Piras M, Bonnycastle LL, Willer CJ, Lyssenko V, Shen H, Kuusisto J, Ebrahim S,

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The Journal of clinical investigation 118(7):2620, 2008 Jul 1 - Who cited this? | PubMed ID: 18521185 | Fulltext

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.

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Zeggini E, Scott LJ, Saxena R, Voight BF, Marchini JL, Hu T, de Bakker PI, Abecasis GR, Almgren P, Andersen G, Ardlie K, Boström KB, Bergman RN, Bonnycastle LL, Borch-Johnsen K, Burtt NP,

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Nature genetics 40(5):638-45, 2008 May - Who cited this? | PubMed ID: 18372903 | Fulltext

Targeted transgenic expression of the mutation causing Hutchinson-Gilford progeria syndrome leads to proliferative and degenerative epidermal disease.

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Sagelius H, Rosengardten Y, Hanif M, Erdos MR, Rozell B, Collins FS, and Eriksson M

Journal of cell science 121(Pt 7):969, 2008 Apr 1 - Who cited this? | PubMed ID: 18334552 | Fulltext

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.

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Scott LJ, Mohlke KL, Bonnycastle LL, Willer CJ, Li Y, Duren WL, Erdos MR, Stringham HM, Chines PS, Jackson AU, Prokunina-Olsson L, Ding CJ, Swift AJ, Narisu N, Hu T, Pruim R,

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Science (New York, N.Y.) 316(5829):1341-5, 2007 Jun 1 - Who cited this? | PubMed ID: 17463248 | Fulltext

A lamin A protein isoform overexpressed in Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and normal cells.

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Cao K, Capell BC, Erdos MR, Djabali K, and Collins FS

Proceedings of the National Academy of Sciences of the United States of America 104(12):4949-54, 2007 Mar 20 - Who cited this? | PubMed ID: 17360355 | Fulltext

Screening of 134 single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes replicates association with 12 SNPs in nine genes.

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Willer CJ, Bonnycastle LL, Conneely KN, Duren WL, Jackson AU, Scott LJ, Narisu N, Chines PS, Skol A, Stringham HM, Petrie J, Erdos MR, Swift AJ, Enloe ST, Sprau AG, Smith E,

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Diabetes 56(1):256, 2007 Jan - Who cited this? | PubMed ID: 17192490 | Fulltext

Common variants in maturity-onset diabetes of the young genes contribute to risk of type 2 diabetes in Finns.

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Bonnycastle LL, Willer CJ, Conneely KN, Jackson AU, Burrill CP, Watanabe RM, Chines PS, Narisu N, Scott LJ, Enloe ST, Swift AJ, Duren WL, Stringham HM, Erdos MR, Riebow NL, Buchanan TA,

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Diabetes 55(9):2534, 2006 Sep - Who cited this? | PubMed ID: 16936201 | Fulltext

Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample.

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Scott LJ, Bonnycastle LL, Willer CJ, Sprau AG, Jackson AU, Narisu N, Duren WL, Chines PS, Stringham HM, Erdos MR, Valle TT, Tuomilehto J, Bergman RN, Mohlke KL, Collins FS, and Boehnke M

Diabetes 55(9):2649-53, 2006 Sep - Who cited this? | PubMed ID: 16936217 | Fulltext

DNase-chip: a high-resolution method to identify DNase I hypersensitive sites using tiled microarrays.

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Crawford GE, Davis S, Scacheri PC, Renaud G, Halawi MJ, Erdos MR, Green R, Meltzer PS, Wolfsberg TG, and Collins FS

Nature methods 3(7):503-9, 2006 Jul - Who cited this? | PubMed ID: 16791207 | Fulltext

Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging.

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Shumaker DK, Dechat T, Kohlmaier A, Adam SA, Bozovsky MR, Erdos MR, Eriksson M, Goldman AE, Khuon S, Collins FS, Jenuwein T, and Goldman RD

Proceedings of the National Academy of Sciences of the United States of America 103(23):8703-8, 2006 Jun 6 - Who cited this? | PubMed ID: 16738054 | Fulltext

Progressive vascular smooth muscle cell defects in a mouse model of Hutchinson-Gilford progeria syndrome.

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Varga R, Eriksson M, Erdos MR, Olive M, Harten I, Kolodgie F, Capell BC, Cheng J, Faddah D, Perkins S, Avallone H, San H, Qu X, Ganesh S, Gordon LB, Virmani R,

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Proceedings of the National Academy of Sciences of the United States of America 103(9):3250-5, 2006 Feb 28 - Who cited this? | PubMed ID: 16492728 | Fulltext

Mitochondrial polymorphisms and susceptibility to type 2 diabetes-related traits in Finns.

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Mohlke KL, Jackson AU, Scott LJ, Peck EC, Suh YD, Chines PS, Watanabe RM, Buchanan TA, Conneely KN, Erdos MR, Narisu N, Enloe S, Valle TT, Tuomilehto J, Bergman RN, Boehnke M,

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Human genetics 118(2):245-54, 2005 Nov - Who cited this? | PubMed ID: 16142453 | Fulltext

Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome.

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Capell BC, Erdos MR, Madigan JP, Fiordalisi JJ, Varga R, Conneely KN, Gordon LB, Der CJ, Cox AD, and Collins FS

Proceedings of the National Academy of Sciences of the United States of America 102(36):12879-84, 2005 Sep 6 - Who cited this? | PubMed ID: 16129833 | Fulltext

Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome.

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Goldman RD, Shumaker DK, Erdos MR, Eriksson M, Goldman AE, Gordon LB, Gruenbaum Y, Khuon S, Mendez M, Varga R, and Collins FS

Proceedings of the National Academy of Sciences of the United States of America 101(24):8963-8, 2004 Jun 15 - Who cited this? | PubMed ID: 15184648 | Fulltext

Genetic variation near the hepatocyte nuclear factor-4 alpha gene predicts susceptibility to type 2 diabetes.

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Silander K, Mohlke KL, Scott LJ, Peck EC, Hollstein P, Skol AD, Jackson AU, Deloukas P, Hunt S, Stavrides G, Chines PS, Erdos MR, Narisu N, Conneely KN, Li C, Fingerlin TE,

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Diabetes 53(4):1141, 2004 Apr - Who cited this? | PubMed ID: 15047633 | Fulltext

A large set of Finnish affected sibling pair families with type 2 diabetes suggests susceptibility loci on chromosomes 6, 11, and 14.

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Silander K, Scott LJ, Valle TT, Mohlke KL, Stringham HM, Wiles KR, Duren WL, Doheny KF, Pugh EW, Chines P, Narisu N, White PP, Fingerlin TE, Jackson AU, Li C, Ghosh S,

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Diabetes 53(3):821-9, 2004 Mar - Who cited this? | PubMed ID: 14988269 | Fulltext

Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome.

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Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM, Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW,

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Nature 423(6937):293-8, 2003 May 15 - Who cited this? | PubMed ID: 12714972 | Fulltext

High-throughput screening for evidence of association by using mass spectrometry genotyping on DNA pools.

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Mohlke KL, Erdos MR, Scott LJ, Fingerlin TE, Jackson AU, Silander K, Hollstein P, Boehnke M, and Collins FS

Proceedings of the National Academy of Sciences of the United States of America 99(26):16928-33, 2002 Dec 24 - Who cited this? | PubMed ID: 12482934 | Fulltext

Variation in three single nucleotide polymorphisms in the calpain-10 gene not associated with type 2 diabetes in a large Finnish cohort.

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Fingerlin TE, Erdos MR, Watanabe RM, Wiles KR, Stringham HM, Mohlke KL, Silander K, Valle TT, Buchanan TA, Tuomilehto J, Bergman RN, Boehnke M, and Collins FS

Diabetes 51(5):1644-8, 2002 May - Who cited this? | PubMed ID: 11978669 | Fulltext

The peroxisome proliferator-activated receptor-gamma2 Pro12A1a variant: association with type 2 diabetes and trait differences.

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Douglas JA, Erdos MR, Watanabe RM, Braun A, Johnston CL, Oeth P, Mohlke KL, Valle TT, Ehnholm C, Buchanan TA, Bergman RN, Collins FS, Boehnke M, and Tuomilehto J

Diabetes 50(4):886-90, 2001 Apr - Who cited this? | PubMed ID: 11289057 | Fulltext

The Finland-United States investigation of non-insulin-dependent diabetes mellitus genetics (FUSION) study. I. An autosomal genome scan for genes that predispose to type 2 diabetes.

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Ghosh S, Watanabe RM, Valle TT, Hauser ER, Magnuson VL, Langefeld CD, Ally DS, Mohlke KL, Silander K, Kohtamäki K, Chines P, Balow Jr J, Birznieks G, Chang J, Eldridge W, Erdos MR,

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American journal of human genetics 67(5):1174-85, 2000 Nov - Who cited this? | PubMed ID: 11032783 | Fulltext

BRCA1 suppresses insulin-like growth factor-I receptor promoter activity: potential interaction between BRCA1 and Sp1.

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Maor SB, Abramovitch S, Erdos MR, Brody LC, and Werner H

Molecular genetics and metabolism 69(2):130-6, 2000 Feb - Who cited this? | PubMed ID: 10720440 | Fulltext

BRCA1 inhibition of estrogen receptor signaling in transfected cells.

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Fan S, Wang J, Yuan R, Ma Y, Meng Q, Erdos MR, Pestell RG, Yuan F, Auborn KJ, Goldberg ID, and Rosen EM

Science (New York, N.Y.) 284(5418):1354-6, 1999 May 21 - Who cited this? | PubMed ID: 10334989 | Fulltext

Type 2 diabetes: evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs.

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Ghosh S, Watanabe RM, Hauser ER, Valle T, Magnuson VL, Erdos MR, Langefeld CD, Balow J, Ally DS, Kohtamaki K, Chines P, Birznieks G, Kaleta HS, Musick A, Te C, Tannenbaum J,

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Proceedings of the National Academy of Sciences of the United States of America 96(5):2198-203, 1999 Mar 2 - Who cited this? | PubMed ID: 10051618 | Fulltext

Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription.

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Agarwal SK, Guru SC, Heppner C, Erdos MR, Collins RM, Park SY, Saggar S, Chandrasekharappa SC, Collins FS, Spiegel AM, Marx SJ, and Burns AL

Cell 96(1):143-52, 1999 Jan 8 - Who cited this? | PubMed ID: 9989505 | Fulltext

Multiple endocrine neoplasia type 1: clinical and genetic features of the hereditary endocrine neoplasias.

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Marx SJ, Agarwal SK, Kester MB, Heppner C, Kim YS, Skarulis MC, James LA, Goldsmith PK, Saggar SK, Park SY, Spiegel AM, Burns AL, Debelenko LV, Zhuang Z, Lubensky IA, Liotta LA,

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Recent progress in hormone research 54:397-438; discussion 438-9, 1999 - Who cited this? | PubMed ID: 10548885 | Fulltext

BRCA1 as a potential human prostate tumor suppressor: modulation of proliferation, damage responses and expression of cell regulatory proteins.

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Fan S, Wang JA, Yuan RQ, Ma YX, Meng Q, Erdos MR, Brody LC, Goldberg ID, and Rosen EM

Oncogene 16(23):3069-82, 1998 Jun 11 - Who cited this? | PubMed ID: 9662340 | Fulltext

Evolutionary sequence comparisons using high-density oligonucleotide arrays.

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Hacia JG, Makalowski W, Edgemon K, Erdos MR, Robbins CM, Fodor SP, Brody LC, and Collins FS

Nature genetics 18(2):155-8, 1998 Feb - Who cited this? | PubMed ID: 9462745 | Fulltext

Human BRCA1 inhibits growth in yeast: potential use in diagnostic testing.

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Humphrey JS, Salim A, Erdos MR, Collins FS, Brody LC, and Klausner RD

Proceedings of the National Academy of Sciences of the United States of America 94(11):5820-5, 1997 May 27 - Who cited this? | PubMed ID: 9159158 | Fulltext

Characterization of EZH1, a human homolog of Drosophila Enhancer of zeste near BRCA1.

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Abel KJ, Brody LC, Valdes JM, Erdos MR, McKinley DR, Castilla LH, Merajver SD, Couch FJ, Friedman LS, Ostermeyer EA, Lynch ED, King MC, Welcsh PL, Osborne-Lawrence S, Spillman M, Bowcock AM,

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Genomics 37(2):161-71, 1996 Oct 15 - Who cited this? | PubMed ID: 8921387 | Fulltext

Detection of eight BRCA1 mutations in 10 breast/ovarian cancer families, including 1 family with male breast cancer.

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Struewing JP, Brody LC, Erdos MR, Kase RG, Giambarresi TR, Smith SA, Collins FS, and Tucker MA

American journal of human genetics 57(1):1-7, 1995 Jul - Who cited this? | PubMed ID: 7611277 | Fulltext

Mutations in the BRCA1 gene in families with early-onset breast and ovarian cancer.

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Castilla LH, Couch FJ, Erdos MR, Hoskins KF, Calzone K, Garber JE, Boyd J, Lubin MB, Deshano ML, and Brody LC

Nature genetics 8(4):387-91, 1994 Dec - Who cited this? | PubMed ID: 7894491 | Fulltext

Identification of immunoreactive forms of thymosin alpha 1 in serum and supernatants by combining HPLC and RIA.

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Naylor PH, Oates KK, Coss MC, Erdos MR, Naylor CW, and Goldstein AL

International journal of immunopharmacology 14(7):1267-78, 1992 Oct - Who cited this? | PubMed ID: 1452411 | Fulltext

Effects of PCB (Aroclor 1254) on non-specific immune parameters in rhesus (Macaca mulatta) monkeys.

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Tryphonas H, Luster MI, White KL, Naylor PH, Erdos MR, Burleson GR, Germolec D, Hodgen M, Hayward S, and Arnold DL

International journal of immunopharmacology 13(6):639-48, 1991 - Who cited this? | PubMed ID: 1721612 | Fulltext

Cellular levels of thymosin immunoreactive peptides are linked to proliferative events: evidence for a nuclear site of action.

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Conteas CN, Mutchnick MG, Palmer KC, Weller FE, Luk GD, Naylor PH, Erdos MR, Goldstein AL, Panneerselvam C, and Horecker BL

Proceedings of the National Academy of Sciences of the United States of America 87(9):3269-73, 1990 May - Who cited this? | PubMed ID: 2375791 | Fulltext

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