Papers authored by Elias PM

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The role of CD44 in cutaneous inflammation.
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Man M, Elias PM, Man W, Wu Y, Bourguignon LY, Feingold KR, and Man MQ
Experimental dermatology 18(11):962-8, 2009 Nov - Who cited this? | PubMed ID: 19469887 | Fulltext
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Abnormal skin barrier in the etiopathogenesis of atopic dermatitis.
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Elias PM and Schmuth M
Current opinion in allergy and clinical immunology 9(5):437-46, 2009 Oct - Who cited this? | PubMed ID: 19550302 | Fulltext
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Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens.
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Scharschmidt TC, Man MQ, Hatano Y, Crumrine D, Gunathilake R, Sundberg JP, Silva KA, Mauro TM, Hupe M, Cho S, Wu Y, Celli A, Schmuth M, Feingold KR, and Elias PM
The Journal of allergy and clinical immunology 124(3):496-506, 506.e1-6, 2009 Sep - Who cited this? | PubMed ID: 19733297 | Fulltext
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Evidence that stress to the epidermal barrier influenced the development of pigmentation in humans.
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Elias PM, Menon G, Wetzel BK, and Williams JJ
Pigment cell & melanoma research 22(4):420-34, 2009 Aug - Who cited this? | PubMed ID: 19508412 | Fulltext
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Ceramide Stimulates ABCA12 Expression via Peroxisome Proliferator-activated Receptor {delta} in Human Keratinocytes.
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Jiang YJ, Uchida Y, Lu B, Kim P, Mao C, Akiyama M, Elias PM, Holleran WM, Grunfeld C, and Feingold KR
The Journal of biological chemistry 284(28):18942-52, 2009 Jul 10 - Who cited this? | PubMed ID: 19429679 | Fulltext
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pH-regulated mechanisms account for pigment-type differences in epidermal barrier function.
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Gunathilake R, Schurer NY, Shoo BA, Celli A, Hachem JP, Crumrine D, Sirimanna G, Feingold KR, Mauro TM, and Elias PM
The Journal of investigative dermatology 129(7):1719-29, 2009 Jul - Who cited this? | PubMed ID: 19177137 | Fulltext
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Maintenance of an acidic stratum corneum prevents emergence of murine atopic dermatitis.
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Hatano Y, Man MQ, Uchida Y, Crumrine D, Scharschmidt TC, Kim EG, Mauro TM, Feingold KR, Elias PM, and Holleran WM
The Journal of investigative dermatology 129(7):1824-35, 2009 Jul - Who cited this? | PubMed ID: 19177139 | Fulltext
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Activators of PPARs and LXR decrease the adverse effects of exogenous glucocorticoids on the epidermis.
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Demerjian M, Choi EH, Man MQ, Chang S, Elias PM, and Feingold KR
Experimental dermatology 18(7):643-9, 2009 Jul - Who cited this? | PubMed ID: 19236478 | Fulltext
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Abnormal skin barrier in the etiopathogenesis of atopic dermatitis.
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Elias PM and Schmuth M
Current allergy and asthma reports 9(4):265-72, 2009 Jul - Who cited this? | PubMed ID: 19656472 | Fulltext
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Vitamin D Receptor and Coactivators SRC2 and 3 Regulate Epidermis-Specific Sphingolipid Production and Permeability Barrier Formation.
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Oda Y, Uchida Y, Moradian S, Crumrine D, Elias PM, and Bikle DD
The Journal of investigative dermatology 129(6):1367-78, 2009 Jun - Who cited this? | PubMed ID: 19052561 | Fulltext
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IL-1alpha accelerates stratum corneum formation and improves permeability barrier homeostasis during murine fetal development.
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Jiang YJ, Lu B, Crumrine D, Man MQ, Elias PM, and Feingold KR
Journal of dermatological science 54(2):88-98, 2009 May - Who cited this? | PubMed ID: 19216058 | Fulltext
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The "caveolae brake hypothesis" and the epidermal barrier.
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Roelandt T, Giddelo C, Heughebaert C, Denecker G, Hupe M, Crumrine D, Kusuma A, Haftek M, Roseeuw D, Declercq W, Feingold KR, Elias PM, and Hachem JP
The Journal of investigative dermatology 129(4):927-36, 2009 Apr - Who cited this? | PubMed ID: 19005485 | Fulltext
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Topical peroxisome proliferator activated receptor activators accelerate postnatal stratum corneum acidification.
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Fluhr JW, Man MQ, Hachem JP, Crumrine D, Mauro TM, Elias PM, and Feingold KR
The Journal of investigative dermatology 129(2):365-74, 2009 Feb - Who cited this? | PubMed ID: 18704104 | Fulltext
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Abnormalities in stratum corneum function in patients recovered from leprosy.
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Song SP, Lv CZ, Feingold KR, Hou QN, Li ZY, Guo CY, Elias PM, and Man MQ
Skin pharmacology and physiology 22(3):131-6, 2009 - Who cited this? | PubMed ID: 19136834 | Fulltext
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Variation of skin surface pH, sebum content and stratum corneum hydration with age and gender in a large Chinese population.
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Man MQ, Xin SJ, Song SP, Cho SY, Zhang XJ, Tu CX, Feingold KR, and Elias PM
Skin pharmacology and physiology 22(4):190-9, 2009 - Who cited this? | PubMed ID: 19648780 | Fulltext
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Decreased cutaneous resonance running time in cured leprosy subjects.
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Song SP, Elias PM, Lv CZ, Shi YJ, Guang P, Zhang XJ, Feingold KR, and Man MQ
Skin pharmacology and physiology 22(4):218-24, 2009 - Who cited this? | PubMed ID: 19648783 | Fulltext
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Epidermal Vascular Endothelial Growth Factor Production Is Required for Permeability Barrier Homeostasis, Dermal Angiogenesis, and the Development of Epidermal Hyperplasia. Implications for the Pathogenesis of Psoriasis.
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Elias PM, Arbiser J, Brown BE, Rossiter H, Man MQ, Cerimele F, Crumrine D, Gunathilake R, Choi EH, Uchida Y, Tschachler E, and Feingold KR
The American journal of pathology, 2008 Aug 7 - Who cited this? | PubMed ID: 18688025 | Fulltext
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On the effects of topical synthetic pseudoceramides: Comparison of possible keratinocyte toxicities provoked by the pseudoceramides, PC104 and BIO391, and natural ceramides.
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Uchida Y, Holleran WM, and Elias PM
Journal of dermatological science 51(1):37-43, 2008 Jul - Who cited this? | PubMed ID: 18396015 | Fulltext
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Skin barrier function.
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Elias PM
Current allergy and asthma reports 8(4):299-305, 2008 Jul - Who cited this? | PubMed ID: 18606081 | Fulltext
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Biopositive Effects of Low-Dose UVB on Epidermis: Coordinate Upregulation of Antimicrobial Peptides and Permeability Barrier Reinforcement.
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Hong SP, Kim MJ, Jung MY, Jeon H, Goo J, Ahn SK, Lee SH, Elias PM, and Choi EH
The Journal of investigative dermatology, 2008 Jun 26 - Who cited this? | PubMed ID: 18580964 | Fulltext
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The neuroendocrine peptide catestatin is a cutaneous antimicrobial and induced in the skin after injury.
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Radek KA, Lopez-Garcia B, Hupe M, Niesman IR, Elias PM, Taupenot L, Mahata SK, O'Connor DT, and Gallo RL
The Journal of investigative dermatology 128(6):1525, 2008 Jun - Who cited this? | PubMed ID: 18185531 | Fulltext
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Basis for the barrier abnormality in atopic dermatitis: outside-inside-outside pathogenic mechanisms.
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Elias PM, Hatano Y, and Williams ML
The Journal of allergy and clinical immunology 121(6):1337-43, 2008 Jun - Who cited this? | PubMed ID: 18329087 | Fulltext
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"Outside-to-inside" (and now back to "outside") pathogenic mechanisms in atopic dermatitis.
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Elias PM and Steinhoff M
The Journal of investigative dermatology 128(5):1067, 2008 May - Who cited this? | PubMed ID: 18408746 | Fulltext
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Co-regulation and interdependence of the mammalian epidermal permeability and antimicrobial barriers.
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Aberg KM, Man MQ, Gallo RL, Ganz T, Crumrine D, Brown BE, Choi EH, Kim DK, Schröder JM, Feingold KR, and Elias PM
The Journal of investigative dermatology 128(4):917, 2008 Apr - Who cited this? | PubMed ID: 17943185 | Fulltext
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Thematic review series: Skin Lipids. Pathogenesis of permeability barrier abnormalities in the ichthyoses: inherited disorders of lipid metabolism.
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Elias PM, Williams ML, Holleran WM, Jiang YJ, and Schmuth M
Journal of lipid research 49(4):697-714, 2008 Apr - Who cited this? | PubMed ID: 18245815 | Fulltext
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Chinese herbal medicine (Tuhuai extract) exhibits topical anti-proliferative and anti-inflammatory activity in murine disease models.
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Man MQ, Shi Y, Man M, Lee SH, Demerjian M, Chang S, Feingold KR, and Elias PM
Experimental dermatology, 2008 Mar 12 - Who cited this? | PubMed ID: 18341576 | Fulltext
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Thematic review series: skin lipids. Peroxisome proliferator-activated receptors and liver X receptors in epidermal biology.
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Schmuth M, Jiang YJ, Dubrac S, Elias PM, and Feingold KR
Journal of lipid research 49(3):499, 2008 Mar - Who cited this? | PubMed ID: 18182682 | Fulltext
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Deficiency of PPARbeta/delta in the Epidermis Results in Defective Cutaneous Permeability Barrier Homeostasis and Increased Inflammation.
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Man MQ, Barish GD, Schmuth M, Crumrine D, Barak Y, Chang S, Jiang Y, Evans RM, Elias PM, and Feingold KR
The Journal of investigative dermatology 128(2):370-7, 2008 Feb - Who cited this? | PubMed ID: 17713572 | Fulltext
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PPAR and LXR activators regulate ABCA12 expression in human keratinocytes.
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Jiang YJ, Lu B, Kim P, Paragh G, Schmitz G, Elias PM, and Feingold KR
The Journal of investigative dermatology 128(1):104, 2008 Jan - Who cited this? | PubMed ID: 17611579 | Fulltext
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Characterization of a hapten-induced, murine model with multiple features of atopic dermatitis: structural, immunologic, and biochemical changes following single versus multiple oxazolone challenges.
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Man MQ, Hatano Y, Lee SH, Man M, Chang S, Feingold KR, Leung DY, Holleran W, Uchida Y, and Elias PM
The Journal of investigative dermatology 128(1):79, 2008 Jan - Who cited this? | PubMed ID: 17671515 | Fulltext
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Acute modulations in permeability barrier function regulate epidermal cornification: role of caspase-14 and the protease-activated receptor type 2.
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Demerjian M, Hachem JP, Tschachler E, Denecker G, Declercq W, Vandenabeele P, Mauro T, Hupe M, Crumrine D, Roelandt T, Houben E, Elias PM, and Feingold KR
The American journal of pathology 172(1):86-97, 2008 Jan - Who cited this? | PubMed ID: 18156206 | Fulltext
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Stratum corneum acidification is impaired in moderately aged human and murine skin.
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Choi EH, Man MQ, Xu P, Xin S, Liu Z, Crumrine DA, Jiang YJ, Fluhr JW, Feingold KR, Elias PM, and Mauro TM
The Journal of investigative dermatology 127(12):2847-56, 2007 Dec - Who cited this? | PubMed ID: 17554364 | Fulltext
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Psychological stress downregulates epidermal antimicrobial peptide expression and increases severity of cutaneous infections in mice.
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Aberg KM, Radek KA, Choi EH, Kim DK, Demerjian M, Hupe M, Kerbleski J, Gallo RL, Ganz T, Mauro T, Feingold KR, and Elias PM
The Journal of clinical investigation 117(11):3339, 2007 Nov - Who cited this? | PubMed ID: 17975669 | Fulltext
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Potassium channel openers accelerate epidermal barrier recovery.
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Denda M, Tsutsumi M, Inoue K, Crumrine D, Feingold KR, and Elias PM
The British journal of dermatology 157(5):888-93, 2007 Nov - Who cited this? | PubMed ID: 17916210 | Fulltext
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Skin barrier structure and function and their relationship to pruritus in end-stage renal disease.
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Yosipovitch G, Duque MI, Patel TS, Ishiuji Y, Guzman-Sanchez DA, Dawn AG, Freedman BI, Chan YH, Crumrine D, and Elias PM
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 22(11):3268-72, 2007 Nov - Who cited this? | PubMed ID: 17595180 | Fulltext
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The regulation of permeability barrier homeostasis.
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Feingold KR, Schmuth M, and Elias PM
The Journal of investigative dermatology 127(7):1574, 2007 Jul - Who cited this? | PubMed ID: 17568800 | Fulltext
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Focal adhesion kinase controls pH-dependent epidermal barrier homeostasis by regulating actin-directed Na+/H+ exchanger 1 plasma membrane localization.
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Ilic D, Mao-Qiang M, Crumrine D, Dolganov G, Larocque N, Xu P, Demerjian M, Brown BE, Lim ST, Ossovskaya V, Schlaepfer DD, Fisher SJ, Feingold KR, Elias PM, and Mauro TM
The American journal of pathology 170(6):2055, 2007 Jun - Who cited this? | PubMed ID: 17525272 | Fulltext
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Fatty acid 2-hydroxylase, encoded by FA2H, accounts for differentiation-associated increase in 2-OH ceramides during keratinocyte differentiation.
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Uchida Y, Hama H, Alderson NL, Douangpanya S, Wang Y, Crumrine DA, Elias PM, and Holleran WM
The Journal of biological chemistry 282(18):13211-9, 2007 May 4 - Who cited this? | PubMed ID: 17355976 | Fulltext
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Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema.
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Sandilands A, Terron-Kwiatkowski A, Hull PR, O'Regan GM, Clayton TH, Watson RM, Carrick T, Evans AT, Liao H, Zhao Y, Campbell LE, Schmuth M, Gruber R, Janecke AR, Elias PM, van Steensel MA, 
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Nature genetics 39(5):650-4, 2007 May - Who cited this? | PubMed ID: 17417636 | Fulltext
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The skin barrier as an innate immune element.
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Elias PM
Seminars in immunopathology 29(1):3-14, 2007 Apr - Who cited this? | PubMed ID: 17621950 | Fulltext
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Loss of functional ELOVL4 depletes very long-chain fatty acids (> or =C28) and the unique omega-O-acylceramides in skin leading to neonatal death.
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Vasireddy V, Uchida Y, Salem N, Kim SY, Mandal MN, Reddy GB, Bodepudi R, Alderson NL, Brown JC, Hama H, Dlugosz A, Elias PM, Holleran WM, and Ayyagari R
Human molecular genetics 16(5):471-82, 2007 Mar 1 - Who cited this? | PubMed ID: 17208947 | Fulltext
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Ichthyosis update: towards a function-driven model of pathogenesis of the disorders of cornification and the role of corneocyte proteins in these disorders.
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Schmuth M, Gruber R, Elias PM, and Williams ML
Advances in dermatology 23:231-56, 2007 - Who cited this? | PubMed ID: 18159904 | Fulltext
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Glucocorticoid blockade reverses psychological stress-induced abnormalities in epidermal structure and function.
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Choi EH, Demerjian M, Crumrine D, Brown BE, Mauro T, Elias PM, and Feingold KR
American journal of physiology. Regulatory, integrative and comparative physiology 291(6):R1657-62, 2006 Dec - Who cited this? | PubMed ID: 16857896 | Fulltext
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Regulation of ABCA1 expression in human keratinocytes and murine epidermis.
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Jiang YJ, Lu B, Kim P, Elias PM, and Feingold KR
Journal of lipid research 47(10):2248-58, 2006 Oct - Who cited this? | PubMed ID: 16825673 | Fulltext
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Serine protease signaling of epidermal permeability barrier homeostasis.
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Hachem JP, Houben E, Crumrine D, Man MQ, Schurer N, Roelandt T, Choi EH, Uchida Y, Brown BE, Feingold KR, and Elias PM
The Journal of investigative dermatology 126(9):2074, 2006 Sep - Who cited this? | PubMed ID: 16691196 | Fulltext
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Barrier dysfunction and pathogenesis of neutral lipid storage disease with ichthyosis (Chanarin-Dorfman syndrome).
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Demerjian M, Crumrine DA, Milstone LM, Williams ML, and Elias PM
The Journal of investigative dermatology 126(9):2032, 2006 Sep - Who cited this? | PubMed ID: 16741516 | Fulltext
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Serine protease activity and residual LEKTI expression determine phenotype in Netherton syndrome.
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Hachem JP, Wagberg F, Schmuth M, Crumrine D, Lissens W, Jayakumar A, Houben E, Mauro TM, Leonardsson G, Brattsand M, Egelrud T, Roseeuw D, Clayman GL, Feingold KR, Williams ML, and Elias PM
The Journal of investigative dermatology 126(7):1609, 2006 Jul - Who cited this? | PubMed ID: 16601670 | Fulltext
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Transepidermal water loss reflects permeability barrier status: validation in human and rodent in vivo and ex vivo models.
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Fluhr JW, Feingold KR, and Elias PM
Experimental dermatology 15(7):483-92, 2006 Jul - Who cited this? | PubMed ID: 16761956 | Fulltext
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Hyaluronan-CD44 interaction stimulates keratinocyte differentiation, lamellar body formation/secretion, and permeability barrier homeostasis.
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Bourguignon LY, Ramez M, Gilad E, Singleton PA, Man MQ, Crumrine DA, Elias PM, and Feingold KR
The Journal of investigative dermatology 126(6):1356-65, 2006 Jun - Who cited this? | PubMed ID: 16557236 | Fulltext
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Differentiation-associated expression of ceramidase isoforms in cultured keratinocytes and epidermis.
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Houben E, Holleran WM, Yaginuma T, Mao C, Obeid LM, Rogiers V, Takagi Y, Elias PM, and Uchida Y
Journal of lipid research 47(5):1063, 2006 May - Who cited this? | PubMed ID: 16477081 | Fulltext
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