Papers authored by Ehses JA

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Free fatty acids induce a proinflammatory response in islets via the abundantly expressed interleukin-1 receptor I.
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Böni-Schnetzler M, Boller S, Debray S, Bouzakri K, Meier DT, Prazak R, Kerr-Conte J, Pattou F, Ehses JA, Schuit FC, and Donath MY
Endocrinology 150(12):5218-29, 2009 Dec - Who cited this? | PubMed ID: 19819943 | Fulltext
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Islet Inflammation Impairs the Pancreatic {beta}-Cell in Type 2 Diabetes.
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Donath MY, Böni-Schnetzler M, Ellingsgaard H, and Ehses JA
Physiology (Bethesda, Md.) 24:325-31, 2009 Dec - Who cited this? | PubMed ID: 19996363 | Fulltext
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Low- and high-density lipoproteins modulate function, apoptosis, and proliferation of primary human and murine pancreatic beta-cells.
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Rütti S, Ehses JA, Sibler RA, Prazak R, Rohrer L, Georgopoulos S, Meier DT, Niclauss N, Berney T, Donath MY, and von Eckardstein A
Endocrinology 150(10):4521-30, 2009 Oct - Who cited this? | PubMed ID: 19628574 | Fulltext
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Pancreatic islet inflammation in type 2 diabetes: From alpha and beta cell compensation to dysfunction.
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Ehses JA, Ellingsgaard H, Böni-Schnetzler M, and Donath MY
Archives of physiology and biochemistry 115(4):240-7, 2009 Oct - Who cited this? | PubMed ID: 19645635 | Fulltext
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Sustained effects of interleukin-1 receptor antagonist treatment in type 2 diabetes.
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Larsen CM, Faulenbach M, Vaag A, Ehses JA, Donath MY, and Mandrup-Poulsen T
Diabetes care 32(9):1663-8, 2009 Sep - Who cited this? | PubMed ID: 19542207 | Fulltext
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IL-1 antagonism reduces hyperglycemia and tissue inflammation in the type 2 diabetic GK rat.
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Ehses JA, Lacraz G, Giroix MH, Schmidlin F, Coulaud J, Kassis N, Irminger JC, Kergoat M, Portha B, Homo-Delarche F, and Donath MY
Proceedings of the National Academy of Sciences of the United States of America 106(33):13998-4003, 2009 Aug 18 - Who cited this? | PubMed ID: 19666548 | Fulltext
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Islet endothelial activation and oxidative stress gene expression is reduced by IL-1Ra treatment in the type 2 diabetic GK rat.
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Lacraz G, Giroix MH, Kassis N, Coulaud J, Galinier A, Noll C, Cornut M, Schmidlin F, Paul JL, Janel N, Irminger JC, Kergoat M, Portha B, Donath MY, Ehses JA, and Homo-Delarche F
PLoS ONE 4(9):e6963, 2009 - Who cited this? | PubMed ID: 19742300 | Fulltext
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Insulitis in type 2 diabetes.
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Böni-Schnetzler M, Ehses JA, Faulenbach M, and Donath MY
Diabetes, obesity & metabolism 10 Suppl 4:201-4, 2008 Nov - Who cited this? | PubMed ID: 18834448 | Fulltext
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Interleukin-6 regulates pancreatic alpha-cell mass expansion.
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Ellingsgaard H, Ehses JA, Hammar EB, Van Lommel L, Quintens R, Martens G, Kerr-Conte J, Pattou F, Berney T, Pipeleers D, Halban PA, Schuit FC, and Donath MY
Proceedings of the National Academy of Sciences of the United States of America 105(35):13163, 2008 Sep 2 - Who cited this? | PubMed ID: 18719127 | Fulltext
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Increased IL-1{beta} mRNA expression in {beta}-cells of individuals with type 2 diabetes and regulation of IL-1{beta} in human islets by glucose and auto-stimulation.
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Böni-Schnetzler M, Thorne J, Parnaud G, Marselli L, Ehses JA, Kerr-Conte J, Pattou F, Halban PA, Weir GC, and Donath MY
The Journal of clinical endocrinology and metabolism, 2008 Jul 29 - Who cited this? | PubMed ID: 18664535 | Fulltext
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Macrophages, cytokines and beta-cell death in Type 2 diabetes.
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Ehses JA, Böni-Schnetzler M, Faulenbach M, and Donath MY
Biochemical Society transactions 36(Pt 3):340-2, 2008 Jun - Who cited this? | PubMed ID: 18481953 | Fulltext
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Islet inflammation in type 2 diabetes: from metabolic stress to therapy.
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Donath MY, Schumann DM, Faulenbach M, Ellingsgaard H, Perren A, and Ehses JA
Diabetes care 31 Suppl 2:S161-4, 2008 Feb - Who cited this? | PubMed ID: 18227479 | Fulltext
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Induction of CXCL1 by extracellular matrix and autocrine enhancement by interleukin-1 in rat pancreatic beta-cells.
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Ribaux P, Ehses JA, Lin-Marq N, Carrozzino F, Böni-Schnetzler M, Hammar E, Irminger JC, Donath MY, and Halban PA
Endocrinology 148(11):5582-90, 2007 Nov - Who cited this? | PubMed ID: 17702850 | Fulltext
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Increased number of islet-associated macrophages in type 2 diabetes.
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Ehses JA, Perren A, Eppler E, Ribaux P, Pospisilik JA, Maor-Cahn R, Gueripel X, Ellingsgaard H, Schneider MK, Biollaz G, Fontana A, Reinecke M, Homo-Delarche F, and Donath MY
Diabetes 56(9):2356-70, 2007 Sep - Who cited this? | PubMed ID: 17579207 | Fulltext
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TNF-alpha -308G>A polymorphism modulates cytokine serum concentrations and macrovascular complications in diabetic patients on aspirin.
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Krayenbuehl PA, Wiesli P, Schmid M, Schmid C, Ehses JA, Hersberger M, Vetter W, and Schulthess G
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 115(5):322-6, 2007 May - Who cited this? | PubMed ID: 17516296 | Fulltext
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Interleukin-1-receptor antagonist in type 2 diabetes mellitus.
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Larsen CM, Faulenbach M, Vaag A, Vølund A, Ehses JA, Seifert B, Mandrup-Poulsen T, and Donath MY
The New England journal of medicine 356(15):1517-26, 2007 Apr 12 - Who cited this? | PubMed ID: 17429083 | Fulltext
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Type 1, type 1.5, and type 2 diabetes: NOD the diabetes we thought it was.
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Donath MY and Ehses JA
Proceedings of the National Academy of Sciences of the United States of America 103(33):12217-8, 2006 Aug 15 - Who cited this? | PubMed ID: 16894143 | Fulltext
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Mechanisms of beta-cell death in type 2 diabetes.
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Donath MY, Ehses JA, Maedler K, Schumann DM, Ellingsgaard H, Eppler E, and Reinecke M
Diabetes 54 Suppl 2:S108-13, 2005 Dec - Who cited this? | PubMed ID: 16306327 | Fulltext
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Leptin modulates beta cell expression of IL-1 receptor antagonist and release of IL-1beta in human islets.
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Maedler K, Sergeev P, Ehses JA, Mathe Z, Bosco D, Berney T, Dayer JM, Reinecke M, Halban PA, and Donath MY
Proceedings of the National Academy of Sciences of the United States of America 101(21):8138, 2004 May 25 - Who cited this? | PubMed ID: 15141093 | Fulltext
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Glucose-dependent insulinotropic polypeptide promotes beta-(INS-1) cell survival via cyclic adenosine monophosphate-mediated caspase-3 inhibition and regulation of p38 mitogen-activated protein kinase.
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Ehses JA, Casilla VR, Doty T, Pospisilik JA, Winter KD, Demuth HU, Pederson RA, and McIntosh CH
Endocrinology 144(10):4433-45, 2003 Oct - Who cited this? | PubMed ID: 12960055 | Fulltext
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Dipeptidyl peptidase IV inhibitor treatment stimulates beta-cell survival and islet neogenesis in streptozotocin-induced diabetic rats.
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Pospisilik JA, Martin J, Doty T, Ehses JA, Pamir N, Lynn FC, Piteau S, Demuth HU, McIntosh CH, and Pederson RA
Diabetes 52(3):741-50, 2003 Mar - Who cited this? | PubMed ID: 12606516 | Fulltext
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A novel pathway for regulation of glucose-dependent insulinotropic polypeptide (GIP) receptor expression in beta cells.
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Lynn FC, Thompson SA, Pospisilik JA, Ehses JA, Hinke SA, Pamir N, McIntosh CH, and Pederson RA
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 17(1):91, 2003 Jan - Who cited this? | PubMed ID: 12475913 | Fulltext
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Dipeptidyl peptidase IV inhibition in animal models of diabetes.
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Pospisilik JA, Ehses JA, Doty T, McIntosh CH, Demuth HU, and Pederson RA
Advances in experimental medicine and biology 524:281-91, 2003 - Who cited this? | PubMed ID: 12675250 | Fulltext
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Glucose-dependent insulinotropic polypeptide activates the Raf-Mek1/2-ERK1/2 module via a cyclic AMP/cAMP-dependent protein kinase/Rap1-mediated pathway.
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Ehses JA, Pelech SL, Pederson RA, and McIntosh CH
The Journal of biological chemistry 277(40):37088-97, 2002 Oct 4 - Who cited this? | PubMed ID: 12138104 | Fulltext
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A new pathway for glucose-dependent insulinotropic polypeptide (GIP) receptor signaling: evidence for the involvement of phospholipase A2 in GIP-stimulated insulin secretion.
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Ehses JA, Lee SS, Pederson RA, and McIntosh CH
The Journal of biological chemistry 276(26):23667-73, 2001 Jun 29 - Who cited this? | PubMed ID: 11323439 | Fulltext
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