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Papers authored by Eeles R

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Childhood predictive genetic testing for Li-Fraumeni syndrome.

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Evans DG, Lunt P, Clancy T, and Eeles R

Familial cancer 9(1):65-9, 2010 Mar - Who cited this? | PubMed ID: 19404774 | Fulltext

The potential value of microseminoprotein-beta as a prostate cancer biomarker and therapeutic target.

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Whitaker HC, Warren AY, Eeles R, Kote-Jarai Z, and Neal DE

The Prostate 70(3):333-40, 2010 Feb 15 - Who cited this? | PubMed ID: 19790236 | Fulltext

Elevated expression of Ki-67 identifies aggressive prostate cancers but does not distinguish BRCA1 or BRCA2 mutation carriers.

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Mitra AV, Jameson C, Barbachano Y, Sodha N, Kote-Jarai Z, Javed A, Bancroft E, Fletcher A, Cooper C, Peock S, IMPACT and EMBRACE Collaborators, Easton D, Eeles R, and Foster CS

Oncology reports 23(2):299-305, 2010 Feb - Who cited this? | PubMed ID: 20043088 | Fulltext

Screening for prostate cancer: the way ahead.

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Kirby RS, Eeles RA, Kote-Jarai Z, Guy M, Easton D, and Fitzpatrick JM

BJU international 105(3):295-7, 2010 Feb - Who cited this? | PubMed ID: 20089095 | Fulltext

Mutation analysis of the MSMB gene in familial prostate cancer.

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Kote-Jarai Z, Leongamornlert D, Tymrakiewicz M, Field H, Guy M, Al Olama AA, Morrison J, O'Brien L, Wilkinson R, Hall A, Sawyer E, Muir K, Hamdy F, Donovan J, Neal D, Easton D,

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British journal of cancer 102(2):414-8, 2010 Jan 19 - Who cited this? | PubMed ID: 19997100 | Fulltext

Prostate cancer segregation analyses using 4390 families from UK and Australian population-based studies.

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Macinnis RJ, Antoniou AC, Eeles RA, Severi G, Guy M, McGuffog L, Hall AL, O'Brien LT, Wilkinson RA, Dearnaley DP, Ardern-Jones AT, Horwich A, Khoo VS, Parker CC, Huddart RA, McCredie MR,

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Genetic epidemiology 34(1):42-50, 2010 Jan - Who cited this? | PubMed ID: 19492347 | Fulltext

Is no news good news? Inconclusive genetic test results in BRCA1 and BRCA2 from patients and professionals' perspectives.

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Ardern-Jones A, Kenen R, Lynch E, Doherty R, and Eeles R

Hereditary cancer in clinical practice 8(1):1, 2010 - Who cited this? | PubMed ID: 20180951 | Fulltext

Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA).

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Osorio A, Milne RL, Pita G, Peterlongo P, Heikkinen T, Simard J, Chenevix-Trench G, Spurdle AB, Beesley J, Chen X, Healey S, KConFab, Neuhausen SL, Ding YC, Couch FJ, Wang X,

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British journal of cancer 101(12):2048-54, 2009 Dec 15 - Who cited this? | PubMed ID: 19920816 | Fulltext

Overexpression of RAD51 occurs in aggressive prostatic cancer.

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Mitra A, Jameson C, Barbachano Y, Sanchez L, Kote-Jarai Z, Peock S, Sodha N, Bancroft E, Fletcher A, Cooper C, Easton D, IMPACT Steering Committee and IMPACT and EMBRACE Collaborators, Eeles R, and Foster CS

Histopathology 55(6):696-704, 2009 Dec - Who cited this? | PubMed ID: 20002770 | Fulltext

Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers.

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Antoniou AC, Sinilnikova OM, McGuffog L, Healey S, Nevanlinna H, Heikkinen T, Simard J, Spurdle AB, Beesley J, Chen X, Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer, Neuhausen SL, Ding YC, Couch FJ, Wang X, Fredericksen Z,

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Human molecular genetics 18(22):4442-56, 2009 Nov 15 - Who cited this? | PubMed ID: 19656774 | Fulltext

The TP53 Arg72Pro and MDM2 309G>T polymorphisms are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers.

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Sinilnikova OM, Antoniou AC, Simard J, Healey S, Léoné M, Sinnett D, Spurdle AB, Beesley J, Chen X, kConFab, Greene MH, Loud JT, Lejbkowicz F, Rennert G, Dishon S, Andrulis IL,

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British journal of cancer 101(8):1456-60, 2009 Oct 20 - Who cited this? | PubMed ID: 19707196 | Fulltext

Multiple loci on 8q24 associated with prostate cancer susceptibility.

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Al Olama AA, Kote-Jarai Z, Giles GG, Guy M, Morrison J, Severi G, Leongamornlert DA, Tymrakiewicz M, Jhavar S, Saunders E, Hopper JL, Southey MC, Muir KR, English DR, Dearnaley DP, Ardern-Jones AT,

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Nature genetics 41(10):1058-60, 2009 Oct - Who cited this? | PubMed ID: 19767752 | Fulltext

Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.

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Eeles RA, Kote-Jarai Z, Al Olama AA, Giles GG, Guy M, Severi G, Muir K, Hopper JL, Henderson BE, Haiman CA, Schleutker J, Hamdy FC, Neal DE, Donovan JL, Stanford JL, Ostrander EA,

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Nature genetics 41(10):1116-21, 2009 Oct - Who cited this? | PubMed ID: 19767753 | Fulltext

No evidence that GATA3 rs570613 SNP modifies breast cancer risk.

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Johnatty SE, Couch FJ, Fredericksen Z, Tarrell R, Spurdle AB, Beesley J, Chen X, kConFab Investigators, AOCS Group, Swedish BRCA1 and BRCA2 Study Collaborators, Gschwantler-Kaulich D, Singer CF, Fuerhauser C, Fink-Retter A, Domchek SM, Nathanson KL,

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Breast cancer research and treatment 117(2):371-9, 2009 Sep - Who cited this? | PubMed ID: 19082709 | Fulltext

Association of folate-pathway gene polymorphisms with the risk of prostate cancer: a population-based nested case-control study, systematic review, and meta-analysis.

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Collin SM, Metcalfe C, Zuccolo L, Lewis SJ, Chen L, Cox A, Davis M, Lane JA, Donovan J, Smith GD, Neal DE, Hamdy FC, Gudmundsson J, Sulem P, Rafnar T, Benediktsdottir KR,

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Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 18(9):2528-39, 2009 Sep - Who cited this? | PubMed ID: 19706844 | Fulltext

Germ-line mutations in mismatch repair genes associated with prostate cancer.

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Grindedal EM, Møller P, Eeles R, Stormorken AT, Bowitz-Lothe IM, Landrø SM, Clark N, Kvåle R, Shanley S, and Maehle L

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 18(9):2460-7, 2009 Sep - Who cited this? | PubMed ID: 19723918 | Fulltext

Dramatic Response to Platinum in a Patient with Cancer with a Germline BRCA2 Mutation.

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Moule R, Sohaib A, and Eeles R

Clinical oncology (Royal College of Radiologists (Great Britain)) 21(6):444-7, 2009 Aug - Who cited this? | PubMed ID: 19574032 | Fulltext

Cancers in BRCA1 and BRCA2 carriers and in women at high risk for breast cancer: MR imaging and mammographic features.

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Gilbert FJ, Warren RM, Kwan-Lim G, Thompson DJ, Eeles RA, Evans DG, Leach MO, and United Kingdom Magnetic Resonance Imaging in Breast Screening (MARIBS) Study Group

Radiology 252(2):358-68, 2009 Aug - Who cited this? | PubMed ID: 19703879 | Fulltext

Eligibility for magnetic resonance imaging screening in the United Kingdom: effect of strict selection criteria and anonymous DNA testing on breast cancer incidence in the MARIBS Study.

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Evans DG, Lennard F, Pointon LJ, Ramus SJ, Gayther SA, Sodha N, Kwan-Lim GE, Leach MO, Warren R, Thompson D, Easton DF, Eeles R, and UK Study of MRI Screening for Breast Cancer in Women at High Risk (MARIBS)

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 18(7):2123-31, 2009 Jul - Who cited this? | PubMed ID: 19567506 | Fulltext

Whole-body magnetic resonance imaging in the detection of skeletal metastases in patients with prostate cancer.

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Venkitaraman R, Cook GJ, Dearnaley DP, Parker CC, Khoo V, Eeles R, Huddart RA, Horwich A, and Sohaib SA

Journal of medical imaging and radiation oncology 53(3):241-7, 2009 Jun - Who cited this? | PubMed ID: 19624290 | Fulltext

Integration of ERG gene mapping and gene-expression profiling identifies distinct categories of human prostate cancer.

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Jhavar S, Brewer D, Edwards S, Kote-Jarai Z, Attard G, Clark J, Flohr P, Christmas T, Thompson A, Parker M, Shepherd C, Stenman UH, Marchbank T, Playford RJ, Woodhouse C, Ogden C,

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BJU international 103(9):1256-69, 2009 May - Who cited this? | PubMed ID: 19040532 | Fulltext

Does magnetic resonance imaging of the spine have a role in the staging of prostate cancer?.

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Venkitaraman R, Cook GJ, Dearnaley DP, Parker CC, Huddart RA, Khoo V, Eeles R, Horwich A, and Sohaib SA

Clinical oncology (Royal College of Radiologists (Great Britain)) 21(1):39-42, 2009 Feb - Who cited this? | PubMed ID: 18993040 | Fulltext

Reproductive and Hormonal Factors, and Ovarian Cancer Risk for BRCA1 and BRCA2 Mutation Carriers: Results from the International BRCA1/2 Carrier Cohort Study.

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Antoniou AC, Rookus M, Andrieu N, Brohet R, Chang-Claude J, Peock S, Cook M, Evans DG, Eeles R, EMBRACE, Nogues C, Faivre L, Gesta P, GENEPSO, van Leeuwen FE, Ausems MG,

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Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 18(2):601-10, 2009 Feb - Who cited this? | PubMed ID: 19190154 | Fulltext

The G67E mutation in hMLH1 is associated with an unusual presentation of Lynch syndrome.

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Clyne M, Offman J, Shanley S, Virgo JD, Radulovic M, Wang Y, Ardern-Jones A, Eeles R, Hoffmann E, and Yu VP

British journal of cancer 100(2):376-80, 2009 Jan 27 - Who cited this? | PubMed ID: 19142183 | Fulltext

A recurrent truncating germline mutation in the BRIP1/FANCJ gene and susceptibility to prostate cancer.

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Kote-Jarai Z, Jugurnauth S, Mulholland S, Leongamornlert DA, Guy M, Edwards S, Tymrakiewitcz M, O'Brien L, Hall A, Wilkinson R, Al Olama AA, Morrison J, Muir K, Neal D, Donovan J, Hamdy F,

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British journal of cancer 100(2):426-30, 2009 Jan 27 - Who cited this? | PubMed ID: 19127258 | Fulltext

Sexual activity and prostate cancer risk in men diagnosed at a younger age.

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Dimitropoulou P, Lophatananon A, Easton D, Pocock R, Dearnaley DP, Guy M, Edwards S, O'Brien L, Hall A, Wilkinson R, Eeles R, Muir KR, UK Genetic Prostate Cancer Study Collaborators, and British Association of Urological Surgeons Section of Oncology

BJU international 103(2):178-85, 2009 Jan - Who cited this? | PubMed ID: 19016689 | Fulltext

Unusual presentation of Lynch Syndrome.

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Yu VP, Novelli M, Payne SJ, Fisher S, Barnetson RA, Frayling IM, Barrett A, Goudie D, Ardern-Jones A, Eeles R, and Shanley S

Hereditary cancer in clinical practice 7(1):12, 2009 - Who cited this? | PubMed ID: 19493351 | Fulltext

Assessing the usefulness of a novel MRI-based breast density estimation algorithm in a cohort of women at high genetic risk of breast cancer: the UK MARIBS study.

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Thompson DJ, Leach MO, Kwan-Lim G, Gayther SA, Ramus SJ, Warsi I, Lennard F, Khazen M, Bryant E, Reed S, Boggis CR, Evans DG, Eeles RA, Easton DF, Warren RM, and UK study of MRI screening for breast cancer in women at high risk (MARIBS)

Breast cancer research : BCR 11(6):R80, 2009 - Who cited this? | PubMed ID: 19903338 | Fulltext

TEAD1 and c-Cbl are novel prostate basal cell markers that correlate with poor clinical outcome in prostate cancer.

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Knight JF, Shepherd CJ, Rizzo S, Brewer D, Jhavar S, Dodson AR, Cooper CS, Eeles R, Falconer A, Kovacs G, Garrett MD, Norman AR, Shipley J, and Hudson DL

British journal of cancer 99(11):1849-58, 2008 Dec 2 - Who cited this? | PubMed ID: 19002168 | Fulltext

"BRCAness" Syndrome in Ovarian Cancer: A Case-Control Study Describing the Clinical Features and Outcome of Patients With Epithelial Ovarian Cancer Associated With BRCA1 and BRCA2 Mutations.

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Tan DS, Rothermundt C, Thomas K, Bancroft E, Eeles R, Shanley S, Ardern-Jones A, Norman A, Kaye SB, and Gore ME

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 26(34):5530-6, 2008 Dec 1 - Who cited this? | PubMed ID: 18955455 | Fulltext

Association study of prostate cancer susceptibility variants with risks of invasive ovarian, breast, and colorectal cancer.

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Song H, Koessler T, Ahmed S, Ramus SJ, Kjaer SK, Dicioccio RA, Wozniak E, Hogdall E, Whittemore AS, McGuire V, Ponder BA, Turnbull C, Hines S, Rahman N, Breast Cancer Susceptibility Collaboration UK, Eeles RA,

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Cancer research 68(21):8837-42, 2008 Nov 1 - Who cited this? | PubMed ID: 18974127 | Fulltext

Genome-wide association studies in cancer.

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Easton DF and Eeles RA

Human molecular genetics 17(R2):R109-15, 2008 Oct 15 - Who cited this? | PubMed ID: 18852198 | Fulltext

Biopsy tissue microarray study of Ki-67 expression in untreated, localized prostate cancer managed by active surveillance.

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Jhavar S, Bartlett J, Kovacs G, Corbishley C, Dearnaley D, Eeles R, Khoo V, Huddart R, Horwich A, Thompson A, Norman A, Brewer D, Cooper CS, and Parker C

Prostate cancer and prostatic diseases, 2008 Sep 2 - Who cited this? | PubMed ID: 18762814 | Fulltext

A pilot study of compositional analysis of the breast and estimation of breast mammographic density using three-dimensional T1-weighted magnetic resonance imaging.

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Khazen M, Warren RM, Boggis CR, Bryant EC, Reed S, Warsi I, Pointon LJ, Kwan-Lim GE, Thompson D, Eeles R, Easton D, Evans DG, Leach MO, and Collaborators in the United Kingdom Medical Research Council Magnetic Resonance Imaging in Breast Screening (MARIBS) Study

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 17(9):2268-74, 2008 Sep - Who cited this? | PubMed ID: 18768492 | Fulltext

Communicating genetics research results to families: problems arising when the patient participant is deceased.

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Ormondroyd E, Moynihan C, Ardern-Jones A, Eeles R, Foster C, Davolls S, and Watson M

Psycho-oncology 17(8):804, 2008 Aug 7 - Who cited this? | PubMed ID: 18688787 | Fulltext

Genetic testing for BRCA1: effects of a randomised study of knowledge provision on interest in testing and long term test uptake; implications for the NICE guidelines.

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Hall J, Gray S, A'hern R, Shanley S, Watson M, Kash K, Croyle R, and Eeles R

Familial cancer, 2008 Aug 5 - Who cited this? | PubMed ID: 18679829 | Fulltext

Multiple novel prostate cancer predisposition loci confirmed by an international study: the PRACTICAL Consortium.

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Kote-Jarai Z, Easton DF, Stanford JL, Ostrander EA, Schleutker J, Ingles SA, Schaid D, Thibodeau S, Dörk T, Neal D, Cox A, Maier C, Vogel W, Guy M, Muir K, Lophatananon A,

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Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 17(8):2052-61, 2008 Aug - Who cited this? | PubMed ID: 18708398 | Fulltext

Multiple Loci with different cancer specificities within the 8q24 gene desert.

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Ghoussaini M, Song H, Koessler T, Al Olama AA, Kote-Jarai Z, Driver KE, Pooley KA, Ramus SJ, Kjaer SK, Hogdall E, DiCioccio RA, Whittemore AS, Gayther SA, Giles GG, Guy M, Edwards SM,

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Journal of the National Cancer Institute 100(13):962, 2008 Jul 2 - Who cited this? | PubMed ID: 18577746 | Fulltext

Predicting the likelihood of carrying a BRCA1 or BRCA2 mutation: validation of BOADICEA, BRCAPRO, IBIS, Myriad and the Manchester scoring system using data from UK genetics clinics.

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Antoniou AC, Hardy R, Walker L, Evans DG, Shenton A, Eeles R, Shanley S, Pichert G, Izatt L, Rose S, Douglas F, Eccles D, Morrison PJ, Scott J, Zimmern RL, Easton DF,

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Journal of medical genetics 45(7):425-31, 2008 Jul - Who cited this? | PubMed ID: 18413374 | Fulltext

Glutathione-S-transferase M1, T1 and P1 polymorphisms, and breast cancer risk, in BRCA1/2 mutation carriers.

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Kadouri L, Kote-Jarai Z, Hubert A, Baras M, Abeliovich D, Hamburger T, Peretz T, and Eeles RA

British journal of cancer 98(12):2006-10, 2008 Jun 17 - Who cited this? | PubMed ID: 18542066 | Fulltext

Diagnostic radiation procedures and risk of prostate cancer.

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Myles P, Evans S, Lophatananon A, Dimitropoulou P, Easton D, Key T, Pocock R, Dearnaley D, Guy M, Edwards S, O'Brien L, Gehr-Swain B, Hall A, Wilkinson R, Eeles R, and Muir K

British journal of cancer 98(11):1852-6, 2008 Jun 3 - Who cited this? | PubMed ID: 18506189 | Fulltext

Surveillance and treatment of malignancy in bloom syndrome.

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Thomas ER, Shanley S, Walker L, and Eeles R

Clinical oncology (Royal College of Radiologists (Great Britain)) 20(5):375-9, 2008 Jun - Who cited this? | PubMed ID: 18359209 | Fulltext

The accuracy of cancer diagnoses as reported in families with head and neck cancer: a case-control study.

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Jefferies S, Goldgar D, MPT Collaborators, and Eeles R

Clinical oncology (Royal College of Radiologists (Great Britain)) 20(4):309-14, 2008 May - Who cited this? | PubMed ID: 18329258 | Fulltext

Intrinsic markers of tumour hypoxia and angiogenesis in localised prostate cancer and outcome of radical treatment: a retrospective analysis of two randomised radiotherapy trials and one surgical cohort study.

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Vergis R, Corbishley CM, Norman AR, Bartlett J, Jhavar S, Borre M, Heeboll S, Horwich A, Huddart R, Khoo V, Eeles R, Cooper C, Sydes M, Dearnaley D, and Parker C

The lancet oncology 9(4):342, 2008 Apr - Who cited this? | PubMed ID: 18343725 | Fulltext

Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers.

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Antoniou AC, Spurdle AB, Sinilnikova OM, Healey S, Pooley KA, Schmutzler RK, Versmold B, Engel C, Meindl A, Arnold N, Hofmann W, Sutter C, Niederacher D, Deissler H, Caldes T, Kämpjärvi K,

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American journal of human genetics 82(4):937-48, 2008 Apr - Who cited this? | PubMed ID: 18355772 | Fulltext

Complex patterns of ETS gene alteration arise during cancer development in the human prostate.

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Clark J, Attard G, Jhavar S, Flohr P, Reid A, De-Bono J, Eeles R, Scardino P, Cuzick J, Fisher G, Parker MD, Foster CS, Berney D, Kovacs G, and Cooper CS

Oncogene 27(14):1993-2003, 2008 Mar 27 - Who cited this? | PubMed ID: 17922029 | Fulltext

Risk-reducing salpingo-oophorectomy for the prevention of BRCA1- and BRCA2-associated breast and gynecologic cancer: a multicenter, prospective study.

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Kauff ND, Domchek SM, Friebel TM, Robson ME, Lee J, Garber JE, Isaacs C, Evans DG, Lynch H, Eeles RA, Neuhausen SL, Daly MB, Matloff E, Blum JL, Sabbatini P, Barakat RR,

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Journal of clinical oncology : official journal of the American Society of Clinical Oncology 26(8):1331-7, 2008 Mar 10 - Who cited this? | PubMed ID: 18268356 | Fulltext

Multiple newly identified loci associated with prostate cancer susceptibility.

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Eeles RA, Kote-Jarai Z, Giles GG, Olama AA, Guy M, Jugurnauth SK, Mulholland S, Leongamornlert DA, Edwards SM, Morrison J, Field HI, Southey MC, Severi G, Donovan JL, Hamdy FC, Dearnaley DP,

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Nature genetics 40(3):316, 2008 Mar - Who cited this? | PubMed ID: 18264097 | Fulltext

Prostate cancer in male BRCA1 and BRCA2 mutation carriers has a more aggressive phenotype.

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Mitra A, Fisher C, Foster CS, Jameson C, Barbachanno Y, Bartlett J, Bancroft E, Doherty R, Kote-Jarai Z, Peock S, Easton D, , and Eeles R

British journal of cancer 98(2):502, 2008 Jan 29 - Who cited this? | PubMed ID: 18182994 | Fulltext

Detection of TMPRSS2-ERG Translocations in Human Prostate Cancer by Expression Profiling Using GeneChip Human Exon 1.0 ST Arrays.

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Jhavar S, Reid A, Clark J, Kote-Jarai Z, Christmas T, Thompson A, Woodhouse C, Ogden C, Fisher C, Corbishley C, De-Bono J, Eeles R, Brewer D, and Cooper C

The Journal of molecular diagnostics : JMD 10(1):50-7, 2008 Jan - Who cited this? | PubMed ID: 18165275 | Fulltext

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