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Papers authored by Edelmann W

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Msh2-dependent DNA repair mitigates a unique susceptibility of B cell progenitors to c-Myc-induced lymphomas.

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Nepal RM, Tong L, Kolaj B, Edelmann W, and Martin A

Proceedings of the National Academy of Sciences of the United States of America 106(44):18698-703, 2009 Nov 3 - Who cited this? | PubMed ID: 19837692 | Fulltext

Involvement of Exo1b in DNA damage-induced apoptosis.

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Bolderson E, Richard DJ, Edelmann W, and Khanna KK

Nucleic acids research 37(10):3452-63, 2009 Jun - Who cited this? | PubMed ID: 19339515 | Fulltext

A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair.

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Kadyrov FA, Genschel J, Fang Y, Penland E, Edelmann W, and Modrich P

Proceedings of the National Academy of Sciences of the United States of America 106(21):8495-500, 2009 May 26 - Who cited this? | PubMed ID: 19420220 | Fulltext

MSH2 ATPase Domain Mutation Affects CTG*CAG Repeat Instability in Transgenic Mice.

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Tomé S, Holt I, Edelmann W, Morris GE, Munnich A, Pearson CE, and Gourdon G

PLoS genetics 5(5):e1000482, 2009 May - Who cited this? | PubMed ID: 19436705 | Fulltext

Mouse models of colon cancer.

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Taketo MM and Edelmann W

Gastroenterology 136(3):780-98, 2009 Mar - Who cited this? | PubMed ID: 19263594 | Fulltext

Perforin-mediated suppression of B-cell lymphoma.

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Bolitho P, Street SE, Westwood JA, Edelmann W, Macgregor D, Waring P, Murray WK, Godfrey DI, Trapani JA, Johnstone RW, and Smyth MJ

Proceedings of the National Academy of Sciences of the United States of America 106(8):2723-8, 2009 Feb 24 - Who cited this? | PubMed ID: 19196996 | Fulltext

O6-methylguanine-induced cell death involves exonuclease 1 as well as DNA mismatch recognition in vivo.

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Klapacz J, Meira LB, Luchetti DG, Calvo JA, Bronson RT, Edelmann W, and Samson LD

Proceedings of the National Academy of Sciences of the United States of America 106(2):576-81, 2009 Jan 13 - Who cited this? | PubMed ID: 19124772 | Fulltext

Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genes.

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Dragileva E, Hendricks A, Teed A, Gillis T, Lopez ET, Friedberg EC, Kucherlapati R, Edelmann W, Lunetta KL, Macdonald ME, and Wheeler VC

Neurobiology of disease 33(1):37-47, 2009 Jan - Who cited this? | PubMed ID: 18930147 | Fulltext

Reassessment of the Role of Mut S Homolog 5 in Ig Class Switch Recombination Shows Lack of Involvement in cis- and trans-Switching.

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Guikema JE, Schrader CE, Leus NG, Ucher A, Linehan EK, Werling U, Edelmann W, and Stavnezer J

Journal of immunology (Baltimore, Md. : 1950) 181(12):8450-9, 2008 Dec 15 - Who cited this? | PubMed ID: 19050263 | Fulltext

Obesity enhances gastrointestinal tumorigenesis in Apc-mutant mice.

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Gravaghi C, Bo J, Laperle KM, Quimby F, Kucherlapati R, Edelmann W, and Lamprecht SA

International journal of obesity (2005) 32(11):1716-9, 2008 Nov - Who cited this? | PubMed ID: 18725892 | Fulltext

Ubiquitylated PCNA plays a role in somatic hypermutation and class-switch recombination and is required for meiotic progression.

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Roa S, Avdievich E, Peled JU, Maccarthy T, Werling U, Kuang FL, Kan R, Zhao C, Bergman A, Cohen PE, Edelmann W, and Scharff MD

Proceedings of the National Academy of Sciences of the United States of America 105(42):16248-53, 2008 Oct 21 - Who cited this? | PubMed ID: 18854411 | Fulltext

Genetic assessment of the importance of galectin-3 in cancer initiation, progression and dissemination in mice.

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Eude-Le Parco I, Gendronneau G, N'guyen T, Delacour D, Thijssen VL, Edelmann W, Peuchmaur M, and Poirier F

Glycobiology, 2008 Oct 10 - Who cited this? | PubMed ID: 18849326 | Fulltext

Dietary induction of colonic tumors in a mouse model of sporadic colon cancer.

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Yang K, Kurihara N, Fan K, Newmark H, Rigas B, Bancroft L, Corner G, Livote E, Lesser M, Edelmann W, Velcich A, Lipkin M, and Augenlicht L

Cancer research 68(19):7803-10, 2008 Oct 1 - Who cited this? | PubMed ID: 18829535 | Fulltext

Apoptotic function of human PMS2 compromised by the nonsynonymous single-nucleotide polymorphic variant R20Q.

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Marinovic-Terzic I, Yoshioka-Yamashita A, Shimodaira H, Avdievich E, Hunton IC, Kolodner RD, Edelmann W, and Wang JY

Proceedings of the National Academy of Sciences of the United States of America 105(37):13993, 2008 Sep 16 - Who cited this? | PubMed ID: 18768816 | Fulltext

Interaction of Muc2 and Apc on Wnt signaling and in intestinal tumorigenesis: potential role of chronic inflammation.

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Yang K, Popova NV, Yang WC, Lozonschi I, Tadesse S, Kent S, Bancroft L, Matise I, Cormier RT, Scherer SJ, Edelmann W, Lipkin M, Augenlicht L, and Velcich A

Cancer research 68(18):7313, 2008 Sep 15 - Who cited this? | PubMed ID: 18794118 | Fulltext

MUS81 Generates a Subset of MLH1-MLH3-Independent Crossovers in Mammalian Meiosis.

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Holloway JK, Booth J, Edelmann W, McGowan CH, and Cohen PE

PLoS genetics 4(9), 2008 Sep - Who cited this? | PubMed ID: 18787696 | Fulltext

Dietary calcium and cholecalciferol modulate cyclin D1 expression, apoptosis, and tumorigenesis in intestine of adenomatous polyposis coli1638N/+ mice.

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Yang K, Lamprecht SA, Shinozaki H, Fan K, Yang W, Newmark HL, Kopelovich L, Edelmann W, Jin B, Gravaghi C, Augenlicht L, Kucherlapati R, and Lipkin M

The Journal of nutrition 138(9):1658-63, 2008 Sep - Who cited this? | PubMed ID: 18716166 | Fulltext

Analysis of meiotic prophase I in live mouse spermatocytes.

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Morelli MA, Werling U, Edelmann W, Roberson MS, and Cohen PE

Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 2008 Jun 2 - Who cited this? | PubMed ID: 18516692 | Fulltext

Novel roles for MLH3 deficiency and TLE6-like amplification in DNA mismatch repair-deficient gastrointestinal tumorigenesis and progression.

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Chen PC, Kuraguchi M, Velasquez J, Wang Y, Yang K, Edwards R, Gillen D, Edelmann W, Kucherlapati R, and Lipkin SM

PLoS genetics 4(6), 2008 Jun - Who cited this? | PubMed ID: 18551179 | Fulltext

Distinct effects of the recurrent Mlh1G67R mutation on MMR functions, cancer, and meiosis.

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Avdievich E, Reiss C, Scherer SJ, Zhang Y, Maier SM, Jin B, Hou H, Rosenwald A, Riedmiller H, Kucherlapati R, Cohen PE, Edelmann W, and Kneitz B

Proceedings of the National Academy of Sciences of the United States of America 105(11):4247-52, 2008 Mar 18 - Who cited this? | PubMed ID: 18337503 | Fulltext

Comparative analysis of meiotic progression in female mice bearing mutations in genes of the DNA mismatch repair pathway.

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Kan R, Sun X, Kolas NK, Avdievich E, Kneitz B, Edelmann W, and Cohen PE

Biology of reproduction 78(3):462, 2008 Mar - Who cited this? | PubMed ID: 18057311 | Fulltext

The DNA-mismatch repair enzyme hMSH2 modulates UV-B-induced cell cycle arrest and apoptosis in melanoma cells.

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Seifert M, Scherer SJ, Edelmann W, Böhm M, Meineke V, Löbrich M, Tilgen W, and Reichrath J

The Journal of investigative dermatology 128(1):203, 2008 Jan - Who cited this? | PubMed ID: 17611581 | Fulltext

Tumor progression in Apc(1638N) mice with Exo1 and Fen1 deficiencies.

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Kucherlapati M, Nguyen A, Kuraguchi M, Yang K, Fan K, Bronson R, Wei K, Lipkin M, Edelmann W, and Kucherlapati R

Oncogene 26(43):6297, 2007 Sep 20 - Who cited this? | PubMed ID: 17452984 | Fulltext

Exonuclease-1 deletion impairs DNA damage signaling and prolongs lifespan of telomere-dysfunctional mice.

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Schaetzlein S, Kodandaramireddy NR, Ju Z, Lechel A, Stepczynska A, Lilli DR, Clark AB, Rudolph C, Kuhnel F, Wei K, Schlegelberger B, Schirmacher P, Kunkel TA, Greenberg RA, Edelmann W, and Rudolph KL

Cell 130(5):863-77, 2007 Sep 7 - Who cited this? | PubMed ID: 17803909 | Fulltext

[In Process Citation].

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Kneitz B, Ströbel P, Adam P, Edelmann W, Gerharz EW, Schartl M, and Riedmiller H

Der Urologe. Ausg. A 46(9):1091, 2007 Sep - Who cited this? | PubMed ID: 17619846 | Fulltext

Piroxicam increases colon tumorigenesis and promotes apoptosis in Mlh1 +/- /Apc1638(N/+) mice.

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Palmerini E, Fan K, Yang K, Risio M, Edelmann W, Lipkin M, and Biasco G

Anticancer research 27(6B):3807-12, 2007 - Who cited this? | PubMed ID: 18225536 | Fulltext

Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6.

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Hegan DC, Narayanan L, Jirik FR, Edelmann W, Liskay RM, and Glazer PM

Carcinogenesis 27(12):2402, 2006 Dec - Who cited this? | PubMed ID: 16728433 | Fulltext

Mismatch repair proteins as sensors of alkylation DNA damage.

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Wang JY and Edelmann W

Cancer cell 9(6):417-8, 2006 Jun - Who cited this? | PubMed ID: 16766259 | Fulltext

The mismatch repair protein Msh6 influences the in vivo AID targeting to the Ig locus.

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Li Z, Zhao C, Iglesias-Ussel MD, Polonskaya Z, Zhuang M, Yang G, Luo Z, Edelmann W, and Scharff MD

Immunity 24(4):393, 2006 Apr - Who cited this? | PubMed ID: 16618598 | Fulltext

Inactivation of Tbx1 in the pharyngeal endoderm results in 22q11DS malformations.

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Arnold JS, Werling U, Braunstein EM, Liao J, Nowotschin S, Edelmann W, Hebert JM, and Morrow BE

Development (Cambridge, England) 133(5):977-87, 2006 Mar - Who cited this? | PubMed ID: 16452092 | Fulltext

Localization of MMR proteins on meiotic chromosomes in mice indicates distinct functions during prophase I.

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Kolas NK, Svetlanov A, Lenzi ML, Macaluso FP, Lipkin SM, Liskay RM, Greally J, Edelmann W, and Cohen PE

The Journal of cell biology 171(3):447, 2005 Nov 7 - Who cited this? | PubMed ID: 16260499 | Fulltext

Impaired hippocampal long-term potentiation in microtubule-associated protein 1B-deficient mice.

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Zervas M, Opitz T, Edelmann W, Wainer B, Kucherlapati R, and Stanton PK

Journal of neuroscience research 82(1):83-92, 2005 Oct 1 - Who cited this? | PubMed ID: 16118800 | Fulltext

Peroxisome proliferator-activated receptor gamma agonist troglitazone induces colon tumors in normal C57BL/6J mice and enhances colonic carcinogenesis in Apc1638 N/+ Mlh1+/- double mutant mice.

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Yang K, Fan KH, Lamprecht SA, Edelmann W, Kopelovich L, Kucherlapati R, and Lipkin M

International journal of cancer. Journal international du cancer 116(4):495-9, 2005 Sep 10 - Who cited this? | PubMed ID: 15818612 | Fulltext

Functional consequences of DNA mismatch repair missense mutations in murine models and their impact on cancer predisposition.

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Scherer SJ, Avdievich E, and Edelmann W

Biochemical Society transactions 33(Pt 4):689, 2005 Aug - Who cited this? | PubMed ID: 16042575 | Fulltext

(CAG)(n)-hairpin DNA binds to Msh2-Msh3 and changes properties of mismatch recognition.

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Owen BA, Yang Z, Lai M, Gajek M, Badger JD, Hayes JJ, Edelmann W, Kucherlapati R, Wilson TM, and McMurray CT

Nature structural & molecular biology 12(8):663-70, 2005 Aug - Who cited this? | PubMed ID: 16025128 | Fulltext

Mutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability and cancer in mice.

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Wang Y, Putnam CD, Kane MF, Zhang W, Edelmann L, Russell R, Carrión DV, Chin L, Kucherlapati R, Kolodner RD, and Edelmann W

Nature genetics 37(7):750-5, 2005 Jul - Who cited this? | PubMed ID: 15965476 | Fulltext

Distinct DNA-damage-dependent and -independent responses drive the loss of oocytes in recombination-defective mouse mutants.

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Di Giacomo M, Barchi M, Baudat F, Edelmann W, Keeney S, and Jasin M

Proceedings of the National Academy of Sciences of the United States of America 102(3):737, 2005 Jan 18 - Who cited this? | PubMed ID: 15640358 | Fulltext

Environmental aspects of the anaerobic digestion of the organic fraction of municipal solid wastes and of solid agricultural wastes.

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Edelmann W, Baier U, and Engeli H

Water science and technology : a journal of the International Association on Water Pollution Research 52(1-2):203-8, 2005 - Who cited this? | PubMed ID: 16180429 | Fulltext

Lack of MSH2 involvement differentiates V(D)J recombination from other non-homologous end joining events.

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Larijani M, Zaheen A, Frieder D, Wang Y, Wu GE, Edelmann W, and Martin A

Nucleic acids research 33(21):6733-42, 2005 - Who cited this? | PubMed ID: 16314305 | Fulltext

Loss of DNA mismatch repair function and cancer predisposition in the mouse: animal models for human hereditary nonpolyposis colorectal cancer.

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Edelmann L and Edelmann W

American journal of medical genetics. Part C, Seminars in medical genetics 129(1):91-9, 2004 Aug 15 - Who cited this? | PubMed ID: 15264277 | Fulltext

Dominant effects of an Msh6 missense mutation on DNA repair and cancer susceptibility.

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Yang G, Scherer SJ, Shell SS, Yang K, Kim M, Lipkin M, Kucherlapati R, Kolodner RD, and Edelmann W

Cancer cell 6(2):139, 2004 Aug - Who cited this? | PubMed ID: 15324697 | Fulltext

Examination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification.

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Li Z, Scherer SJ, Ronai D, Iglesias-Ussel MD, Peled JU, Bardwell PD, Zhuang M, Lee K, Martin A, Edelmann W, and Scharff MD

The Journal of experimental medicine 200(1):47-59, 2004 Jul 5 - Who cited this? | PubMed ID: 15238604 | Fulltext

Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice.

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Bardwell PD, Woo CJ, Wei K, Li Z, Martin A, Sack SZ, Parris T, Edelmann W, and Scharff MD

Nature immunology 5(2):224-9, 2004 Feb - Who cited this? | PubMed ID: 14716311 | Fulltext

An Msh2 point mutation uncouples DNA mismatch repair and apoptosis.

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Lin DP, Wang Y, Scherer SJ, Clark AB, Yang K, Avdievich E, Jin B, Werling U, Parris T, Kurihara N, Umar A, Kucherlapati R, Lipkin M, Kunkel TA, and Edelmann W

Cancer research 64(2):517-22, 2004 Jan 15 - Who cited this? | PubMed ID: 14744764 | Fulltext

A panel of repeat markers for detection of microsatellite instability in murine tumors.

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Kabbarah O, Mallon MA, Pfeifer JD, Edelmann W, Kucherlapati R, and Goodfellow PJ

Molecular carcinogenesis 38(4):155-9, 2003 Dec - Who cited this? | PubMed ID: 14639654 | Fulltext

Spontaneous aberrant crypt foci in Apc1638N mice with a mutant Apc allele.

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Pretlow TP, Edelmann W, Kucherlapati R, Pretlow TG, and Augenlicht LH

The American journal of pathology 163(5):1757-63, 2003 Nov - Who cited this? | PubMed ID: 14578176 | Fulltext

Msh2 ATPase activity is essential for somatic hypermutation at a-T basepairs and for efficient class switch recombination.

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Martin A, Li Z, Lin DP, Bardwell PD, Iglesias-Ussel MD, Edelmann W, and Scharff MD

The Journal of experimental medicine 198(8):1171-8, 2003 Oct 20 - Who cited this? | PubMed ID: 14568978 | Fulltext

DNA mismatch repair protein Msh6 is required for optimal levels of ultraviolet-B-induced apoptosis in primary mouse fibroblasts.

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Young LC, Peters AC, Maeda T, Edelmann W, Kucherlapati R, Andrew SE, and Tron VA

The Journal of investigative dermatology 121(4):876-80, 2003 Oct - Who cited this? | PubMed ID: 14632208 | Fulltext

Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility.

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Wei K, Clark AB, Wong E, Kane MF, Mazur DJ, Parris T, Kolas NK, Russell R, Hou H, Kneitz B, Yang G, Kunkel TA, Kolodner RD, Cohen PE, and Edelmann W

Genes & development 17(5):603-14, 2003 Mar 1 - Who cited this? | PubMed ID: 12629043 | Fulltext

Regional response leading to tumorigenesis after sulindac in small and large intestine of mice with Apc mutations.

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Yang K, Fan K, Kurihara N, Shinozaki H, Rigas B, Augenlicht L, Kopelovich L, Edelmann W, Kucherlapati R, and Lipkin M

Carcinogenesis 24(3):605-11, 2003 Mar - Who cited this? | PubMed ID: 12663524 | Fulltext

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