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Papers authored by Dziarski R

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A novel antimicrobial peptidoglycan recognition protein in the cornea.

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Ghosh A, Lee S, Dziarski R, and Chakravarti S

Investigative ophthalmology & visual science 50(9):4185-91, 2009 Sep - Who cited this? | PubMed ID: 19387073 | Fulltext

PGLYRP-2 and Nod2 are both required for peptidoglycan-induced arthritis and local inflammation.

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Saha S, Qi J, Wang S, Wang M, Li X, Kim YG, Núñez G, Gupta D, and Dziarski R

Cell host & microbe 5(2):137-50, 2009 Feb 19 - Who cited this? | PubMed ID: 19218085 | Fulltext

Peptidoglycan recognition protein-S (PGRP-S) is upregulated by NF-kappaB.

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Lang MF, Schneider A, Krüger C, Schmid R, Dziarski R, and Schwaninger M

Neuroscience letters 430(2):138-41, 2008 Jan 10 - Who cited this? | PubMed ID: 18035491 | Fulltext

Zebrafish peptidoglycan recognition proteins are bactericidal amidases essential for defense against bacterial infections.

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Li X, Wang S, Qi J, Echtenkamp SF, Chatterjee R, Wang M, Boons GJ, Dziarski R, and Gupta D

Immunity 27(3):518, 2007 Sep - Who cited this? | PubMed ID: 17892854 | Fulltext

Peptidoglycan recognition proteins: pleiotropic sensors and effectors of antimicrobial defences.

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Royet J and Dziarski R

Nature reviews. Microbiology 5(4):264-77, 2007 Apr - Who cited this? | PubMed ID: 17363965 | Fulltext

Human peptidoglycan recognition proteins require zinc to kill both gram-positive and gram-negative bacteria and are synergistic with antibacterial peptides.

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Wang M, Liu LH, Wang S, Li X, Lu X, Gupta D, and Dziarski R

Journal of immunology (Baltimore, Md. : 1950) 178(5):3116-25, 2007 Mar 1 - Who cited this? | PubMed ID: 17312159 | Fulltext

Deadly plague versus mild-mannered TLR4.

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Dziarski R

Nature immunology 7(10):1017-9, 2006 Oct - Who cited this? | PubMed ID: 16985495 | Fulltext

Mammalian PGRPs: novel antibacterial proteins.

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Dziarski R and Gupta D

Cellular microbiology 8(7):1059, 2006 Jul - Who cited this? | PubMed ID: 16819960 | Fulltext

Peptidoglycan recognition proteins are a new class of human bactericidal proteins.

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Lu X, Wang M, Qi J, Wang H, Li X, Gupta D, and Dziarski R

The Journal of biological chemistry 281(9):5895-907, 2006 Mar 3 - Who cited this? | PubMed ID: 16354652 | Fulltext

The peptidoglycan recognition proteins (PGRPs).

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Dziarski R and Gupta D

Genome biology 7(8):232, 2006 - Who cited this? | PubMed ID: 16930467 | Fulltext

Peptidoglycan recognition protein 2 (N-acetylmuramoyl-L-Ala amidase) is induced in keratinocytes by bacteria through the p38 kinase pathway.

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Wang H, Gupta D, Li X, and Dziarski R

Infection and immunity 73(11):7216-25, 2005 Nov - Who cited this? | PubMed ID: 16239516 | Fulltext

Identification of serum N-acetylmuramoyl-l-alanine amidase as liver peptidoglycan recognition protein 2.

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Zhang Y, van der Fits L, Voerman JS, Melief MJ, Laman JD, Wang M, Wang H, Wang M, Li X, Walls CD, Gupta D, and Dziarski R

Biochimica et biophysica acta 1752(1):34-46, 2005 Aug 31 - Who cited this? | PubMed ID: 16054449 | Fulltext

Staphylococcus aureus peptidoglycan is a toll-like receptor 2 activator: a reevaluation.

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Dziarski R and Gupta D

Infection and immunity 73(8):5212-6, 2005 Aug - Who cited this? | PubMed ID: 16041042 | Fulltext

Peptidoglycan recognition in innate immunity.

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Dziarski R and Gupta D

Journal of endotoxin research 11(5):304-10, 2005 - Who cited this? | PubMed ID: 16263004 | Fulltext

Peptidoglycan recognition proteins (PGRPs).

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Dziarski R

Molecular immunology 40(12):877-86, 2004 Feb - Who cited this? | PubMed ID: 14698226 | Fulltext

Human peptidoglycan recognition protein-L is an N-acetylmuramoyl-L-alanine amidase.

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Wang ZM, Li X, Cocklin RR, Wang M, Wang M, Fukase K, Inamura S, Kusumoto S, Gupta D, and Dziarski R

The Journal of biological chemistry 278(49):49044-52, 2003 Dec 5 - Who cited this? | PubMed ID: 14506276 | Fulltext

Recognition of bacterial peptidoglycan by the innate immune system.

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Dziarski R

Cellular and molecular life sciences : CMLS 60(9):1793-804, 2003 Sep - Who cited this? | PubMed ID: 14523544 | Fulltext

Defect in neutrophil killing and increased susceptibility to infection with nonpathogenic gram-positive bacteria in peptidoglycan recognition protein-S (PGRP-S)-deficient mice.

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Dziarski R, Platt KA, Gelius E, Steiner H, and Gupta D

Blood 102(2):689-97, 2003 Jul 15 - Who cited this? | PubMed ID: 12649138 | Fulltext

A subset of Toll-like receptor ligands induces cross-presentation by bone marrow-derived dendritic cells.

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Datta SK, Redecke V, Prilliman KR, Takabayashi K, Corr M, Tallant T, DiDonato J, Dziarski R, Akira S, Schoenberger SP, and Raz E

Journal of immunology (Baltimore, Md. : 1950) 170(8):4102-10, 2003 Apr 15 - Who cited this? | PubMed ID: 12682240 | Fulltext

Bacterial peptidoglycan-induced tnf-alpha transcription is mediated through the transcription factors Egr-1, Elk-1, and NF-kappaB.

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Xu Z, Dziarski R, Wang Q, Swartz K, Sakamoto KM, and Gupta D

Journal of immunology (Baltimore, Md. : 1950) 167(12):6975-82, 2001 Dec 15 - Who cited this? | PubMed ID: 11739517 | Fulltext

Bacterial peptidoglycan binds to tubulin.

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Dziarski R, Rasenick MM, and Gupta D

Biochimica et biophysica acta 1524(1):17-26, 2001 Nov 15 - Who cited this? | PubMed ID: 11078954 | Fulltext

Peptidoglycan recognition proteins: a novel family of four human innate immunity pattern recognition molecules.

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Liu C, Xu Z, Gupta D, and Dziarski R

The Journal of biological chemistry 276(37):34686-94, 2001 Sep 14 - Who cited this? | PubMed ID: 11461926 | Fulltext

Micrococci and peptidoglycan activate TLR2-->MyD88-->IRAK-->TRAF-->NIK-->IKK-->NF-kappaB signal transduction pathway that induces transcription of interleukin-8.

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Wang Q, Dziarski R, Kirschning CJ, Muzio M, and Gupta D

Infection and immunity 69(4):2270-6, 2001 Apr - Who cited this? | PubMed ID: 11254583 | Fulltext

MD-2 enables Toll-like receptor 2 (TLR2)-mediated responses to lipopolysaccharide and enhances TLR2-mediated responses to Gram-positive and Gram-negative bacteria and their cell wall components.

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Dziarski R, Wang Q, Miyake K, Kirschning CJ, and Gupta D

Journal of immunology (Baltimore, Md. : 1950) 166(3):1938-44, 2001 Feb 1 - Who cited this? | PubMed ID: 11160242 | Fulltext

Soluble CD14 enhances membrane CD14-mediated responses to peptidoglycan: structural requirements differ from those for responses to lipopolysaccharide.

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Dziarski R, Viriyakosol S, Kirkland TN, and Gupta D

Infection and immunity 68(9):5254-60, 2000 Sep - Who cited this? | PubMed ID: 10948152 | Fulltext

Mammalian peptidoglycan recognition protein binds peptidoglycan with high affinity, is expressed in neutrophils, and inhibits bacterial growth.

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Liu C, Gelius E, Liu G, Steiner H, and Dziarski R

The Journal of biological chemistry 275(32):24490-9, 2000 Aug 11 - Who cited this? | PubMed ID: 10827080 | Fulltext

Chemokines are the main proinflammatory mediators in human monocytes activated by Staphylococcus aureus, peptidoglycan, and endotoxin.

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Wang ZM, Liu C, and Dziarski R

The Journal of biological chemistry 275(27):20260-7, 2000 Jul 7 - Who cited this? | PubMed ID: 10751418 | Fulltext

Interactions of CD14 with components of gram-positive bacteria.

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Dziarski R, Ulmer AJ, and Gupta D

Chemical immunology 74:83-107, 2000 - Who cited this? | PubMed ID: 10608083 | Fulltext

Role of MD-2 in TLR2- and TLR4-mediated recognition of Gram-negative and Gram-positive bacteria and activation of chemokine genes.

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Dziarski R and Gupta D

Journal of endotoxin research 6(5):401-5, 2000 - Who cited this? | PubMed ID: 11521063 | Fulltext

Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2.

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Yoshimura A, Lien E, Ingalls RR, Tuomanen E, Dziarski R, and Golenbock D

Journal of immunology (Baltimore, Md. : 1950) 163(1):1-5, 1999 Jul 1 - Who cited this? | PubMed ID: 10384090 | Fulltext

Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2.

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Schwandner R, Dziarski R, Wesche H, Rothe M, and Kirschning CJ

The Journal of biological chemistry 274(25):17406-9, 1999 Jun 18 - Who cited this? | PubMed ID: 10364168 | Fulltext

Bacterial peptidoglycan induces CD14-dependent activation of transcription factors CREB/ATF and AP-1.

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Gupta D, Wang Q, Vinson C, and Dziarski R

The Journal of biological chemistry 274(20):14012-20, 1999 May 14 - Who cited this? | PubMed ID: 10318814 | Fulltext

Endothelial and epithelial cells do not respond to complexes of peptidoglycan with soluble CD14 but are activated indirectly by peptidoglycan-induced tumor necrosis factor-alpha and interleukin-1 from monocytes.

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Jin Y, Gupta D, and Dziarski R

The Journal of infectious diseases 177(6):1629-38, 1998 Jun - Who cited this? | PubMed ID: 9607843 | Fulltext

Binding of bacterial peptidoglycan to CD14.

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Dziarski R, Tapping RI, and Tobias PS

The Journal of biological chemistry 273(15):8680-90, 1998 Apr 10 - Who cited this? | PubMed ID: 9535844 | Fulltext

Lipopolysaccharide and peptidoglycan: CD14-dependent bacterial inducers of inflammation.

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Rietschel ET, Schletter J, Weidemann B, El-Samalouti V, Mattern T, Zähringer U, Seydel U, Brade H, Flad HD, Kusumoto S, Gupta D, Dziarski R, and Ulmer AJ

Microbial drug resistance (Larchmont, N.Y.) 4(1):37-44, 1998 - Who cited this? | PubMed ID: 9533723 | Fulltext

Specific binding of soluble peptidoglycan and muramyldipeptide to CD14 on human monocytes.

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Weidemann B, Schletter J, Dziarski R, Kusumoto S, Stelter F, Rietschel ET, Flad HD, and Ulmer AJ

Infection and immunity 65(3):858-64, 1997 Mar - Who cited this? | PubMed ID: 9038288 | Fulltext

Differential activation of extracellular signal-regulated kinase (ERK) 1, ERK2, p38, and c-Jun NH2-terminal kinase mitogen-activated protein kinases by bacterial peptidoglycan.

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Dziarski R, Jin YP, and Gupta D

The Journal of infectious diseases 174(4):777-85, 1996 Oct - Who cited this? | PubMed ID: 8843216 | Fulltext

CD14 is a cell-activating receptor for bacterial peptidoglycan.

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Gupta D, Kirkland TN, Viriyakosol S, and Dziarski R

The Journal of biological chemistry 271(38):23310-6, 1996 Sep 20 - Who cited this? | PubMed ID: 8798531 | Fulltext

Peptidoglycan induces transcription and secretion of TNF-alpha and activation of lyn, extracellular signal-regulated kinase, and rsk signal transduction proteins in mouse macrophages.

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Gupta D, Jin YP, and Dziarski R

Journal of immunology (Baltimore, Md. : 1950) 155(5):2620-30, 1995 Sep 1 - Who cited this? | PubMed ID: 7650392 | Fulltext

Soluble peptidoglycan-induced monokine production can be blocked by anti-CD14 monoclonal antibodies and by lipid A partial structures.

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Weidemann B, Brade H, Rietschel ET, Dziarski R, Bazil V, Kusumoto S, Flad HD, and Ulmer AJ

Infection and immunity 62(11):4709-15, 1994 Nov - Who cited this? | PubMed ID: 7523297 | Fulltext

Cell-bound albumin is the 70-kDa peptidoglycan-, lipopolysaccharide-, and lipoteichoic acid-binding protein on lymphocytes and macrophages.

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Dziarski R

The Journal of biological chemistry 269(32):20431-6, 1994 Aug 12 - Who cited this? | PubMed ID: 8051139 | Fulltext

Heparin, sulfated heparinoids, and lipoteichoic acids bind to the 70-kDa peptidoglycan/lipopolysaccharide receptor protein on lymphocytes.

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Dziarski R and Gupta D

The Journal of biological chemistry 269(3):2100-10, 1994 Jan 21 - Who cited this? | PubMed ID: 8294463 | Fulltext

Isolation of peptidoglycan and soluble peptidoglycan fragments.

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Rosenthal RS and Dziarski R

Methods in enzymology 235:253-85, 1994 - Who cited this? | PubMed ID: 8057899 | Fulltext

Synergistic enhancement of T cell responses and interleukin-1 receptor expression by interleukin-1 and heparin or dextran sulfate.

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Dziarski R

Cellular immunology 145(1):100-10, 1992 Nov - Who cited this? | PubMed ID: 1423638 | Fulltext

Specific endotoxic lipopolysaccharide-binding receptors on murine splenocytes: III. Binding specificity and characterization.

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Dziarski R

Journal of immunology (Baltimore, Md. : 1950) 148(5):1590-1, 1992 Mar 1 - Who cited this? | PubMed ID: 1371531 | Fulltext

Demonstration of peptidoglycan-binding sites on lymphocytes and macrophages by photoaffinity cross-linking.

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Dziarski R

The Journal of biological chemistry 266(8):4713-8, 1991 Mar 15 - Who cited this? | PubMed ID: 2002020 | Fulltext

Peptidoglycan and lipopolysaccharide bind to the same binding site on lymphocytes.

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Dziarski R

The Journal of biological chemistry 266(8):4719-25, 1991 Mar 15 - Who cited this? | PubMed ID: 2002021 | Fulltext

Enhancement of mixed leukocyte reaction and cytotoxic antitumor responses by heparin.

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Dziarski R

Journal of immunology (Baltimore, Md. : 1950) 143(1):356-65, 1989 Jul 1 - Who cited this? | PubMed ID: 2471741 | Fulltext

Correlation between ribosylation of pertussis toxin substrates and inhibition of peptidoglycan-, muramyl dipeptide- and lipopolysaccharide-induced mitogenic stimulation in B lymphocytes.

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Dziarski R

European journal of immunology 19(1):125-30, 1989 Jan - Who cited this? | PubMed ID: 2537732 | Fulltext

Autoimmunity: polyclonal activation or antigen induction?.

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Dziarski R

Immunology today 9(11):340-2, 1988 Nov - Who cited this? | PubMed ID: 3076403 | Fulltext

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