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Papers authored by Distefano PS

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Enhanced gastrointestinal motility with orally active ghrelin receptor agonists.

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Charoenthongtrakul S, Giuliana D, Longo KA, Govek EK, Nolan A, Gagne S, Morgan K, Hixon J, Flynn N, Murphy BJ, Hernández AS, Li J, Tino JA, Gordon DA, Distefano PS, and Geddes BJ

The Journal of pharmacology and experimental therapeutics 329(3):1178-86, 2009 Jun - Who cited this? | PubMed ID: 19252061 | Fulltext

Improved insulin sensitivity and metabolic flexibility in ghrelin receptor knockout mice.

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Longo KA, Charoenthongtrakul S, Giuliana DJ, Govek EK, McDonagh T, Qi Y, Distefano PS, and Geddes BJ

Regulatory peptides 150(1-3):55-61, 2008 Oct 9 - Who cited this? | PubMed ID: 18453014 | Fulltext

Insulin resistance, glycemic control and adiposity: key determinants of healthy lifespan.

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DiStefano PS, Curtis R, and Geddes BJ

Current Alzheimer research 4(2):153-7, 2007 Apr - Who cited this? | PubMed ID: 17430240 | Fulltext

Proapoptotic effects of NARC 1 (= PCSK9), the gene encoding a novel serine proteinase.

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Bingham B, Shen R, Kotnis S, Lo CF, Ozenberger BA, Ghosh N, Kennedy JD, Jacobsen JS, Grenier JM, DiStefano PS, Chiang LW, and Wood A

Cytometry. Part A : the journal of the International Society for Analytical Cytology 69(11):1123-31, 2006 Nov 1 - Who cited this? | PubMed ID: 17051583 | Fulltext

Aging networks in Caenorhabditis elegans: AMP-activated protein kinase (aak-2) links multiple aging and metabolism pathways.

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Curtis R, O'Connor G, and DiStefano PS

Aging cell 5(2):119, 2006 Apr - Who cited this? | PubMed ID: 16626391 | Fulltext

Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage.

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Solomon JM, Pasupuleti R, Xu L, McDonagh T, Curtis R, DiStefano PS, and Huber LJ

Molecular and cellular biology 26(1):28-38, 2006 Jan - Who cited this? | PubMed ID: 16354677 | Fulltext

Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1.

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Napper AD, Hixon J, McDonagh T, Keavey K, Pons JF, Barker J, Yau WT, Amouzegh P, Flegg A, Hamelin E, Thomas RJ, Kates M, Jones S, Navia MA, Saunders JO, DiStefano PS,

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Journal of medicinal chemistry 48(25):8045-54, 2005 Dec 15 - Who cited this? | PubMed ID: 16335928 | Fulltext

Microplate filtration assay for nicotinamide release from NAD using a boronic acid resin.

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McDonagh T, Hixon J, DiStefano PS, Curtis R, and Napper AD

Methods (San Diego, Calif.) 36(4):346-50, 2005 Aug - Who cited this? | PubMed ID: 16085423 | Fulltext

Ageing and metabolism: drug discovery opportunities.

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Curtis R, Geesaman BJ, and DiStefano PS

Nature reviews. Drug discovery 4(7):569-80, 2005 Jul - Who cited this? | PubMed ID: 15976816 | Fulltext

Substrate-specific activation of sirtuins by resveratrol.

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Kaeberlein M, McDonagh T, Heltweg B, Hixon J, Westman EA, Caldwell SD, Napper A, Curtis R, DiStefano PS, Fields S, Bedalov A, and Kennedy BK

The Journal of biological chemistry 280(17):17038-45, 2005 Apr 29 - Who cited this? | PubMed ID: 15684413 | Fulltext

The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans.

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Apfeld J, O'Connor G, McDonagh T, DiStefano PS, and Curtis R

Genes & development 18(24):3004, 2004 Dec 15 - Who cited this? | PubMed ID: 15574588 | Fulltext

Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island.

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Viala J, Chaput C, Boneca IG, Cardona A, Girardin SE, Moran AP, Athman R, Mémet S, Huerre MR, Coyle AJ, DiStefano PS, Sansonetti PJ, Labigne A, Bertin J, Philpott DJ, and Ferrero RL

Nature immunology 5(11):1166-74, 2004 Nov - Who cited this? | PubMed ID: 15489856 | Fulltext

Functional characterization of Narc 1, a novel proteinase related to proteinase K.

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Naureckiene S, Ma L, Sreekumar K, Purandare U, Lo CF, Huang Y, Chiang LW, Grenier JM, Ozenberger BA, Jacobsen JS, Kennedy JD, DiStefano PS, Wood A, and Bingham B

Archives of biochemistry and biophysics 420(1):55-67, 2003 Dec 1 - Who cited this? | PubMed ID: 14622975 | Fulltext

Sodium channel beta4, a new disulfide-linked auxiliary subunit with similarity to beta2.

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Yu FH, Westenbroek RE, Silos-Santiago I, McCormick KA, Lawson D, Ge P, Ferriera H, Lilly J, DiStefano PS, Catterall WA, Scheuer T, and Curtis R

The Journal of neuroscience : the official journal of the Society for Neuroscience 23(20):7577-85, 2003 Aug 20 - Who cited this? | PubMed ID: 12930796 | Fulltext

Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan.

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Girardin SE, Boneca IG, Carneiro LA, Antignac A, Jéhanno M, Viala J, Tedin K, Taha MK, Labigne A, Zähringer U, Coyle AJ, DiStefano PS, Bertin J, Sansonetti PJ, and Philpott DJ

Science (New York, N.Y.) 300(5625):1584-7, 2003 Jun 6 - Who cited this? | PubMed ID: 12791997 | Fulltext

Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1.

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Grenier JM, Wang L, Manji GA, Huang WJ, Al-Garawi A, Kelly R, Carlson A, Merriam S, Lora JM, Briskin M, DiStefano PS, and Bertin J

FEBS letters 530(1-3):73-8, 2002 Oct 23 - Who cited this? | PubMed ID: 12387869 | Fulltext

A requirement for CARMA1 in TCR-induced NF-kappa B activation.

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Wang D, You Y, Case SM, McAllister-Lucas LM, Wang L, DiStefano PS, Nuñez G, Bertin J, and Lin X

Nature immunology 3(9):830-5, 2002 Sep - Who cited this? | PubMed ID: 12154356 | Fulltext

PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing.

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Wang L, Manji GA, Grenier JM, Al-Garawi A, Merriam S, Lora JM, Geddes BJ, Briskin M, DiStefano PS, and Bertin J

The Journal of biological chemistry 277(33):29874-80, 2002 Aug 16 - Who cited this? | PubMed ID: 12019269 | Fulltext

TRPV3 is a calcium-permeable temperature-sensitive cation channel.

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Xu H, Ramsey IS, Kotecha SA, Moran MM, Chong JA, Lawson D, Ge P, Lilly J, Silos-Santiago I, Xie Y, DiStefano PS, Curtis R, and Clapham DE

Nature 418(6894):181-6, 2002 Jul 11 - Who cited this? | PubMed ID: 12077604 | Fulltext

CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis.

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Razmara M, Srinivasula SM, Wang L, Poyet JL, Geddes BJ, DiStefano PS, Bertin J, and Alnemri ES

The Journal of biological chemistry 277(16):13952-8, 2002 Apr 19 - Who cited this? | PubMed ID: 11821383 | Fulltext

DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein.

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Tran H, Brunet A, Grenier JM, Datta SR, Fornace AJ, DiStefano PS, Chiang LW, and Greenberg ME

Science (New York, N.Y.) 296(5567):530-4, 2002 Apr 19 - Who cited this? | PubMed ID: 11964479 | Fulltext

PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa B.

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Manji GA, Wang L, Geddes BJ, Brown M, Merriam S, Al-Garawi A, Mak S, Lora JM, Briskin M, Jurman M, Cao J, DiStefano PS, and Bertin J

The Journal of biological chemistry 277(13):11570-5, 2002 Mar 29 - Who cited this? | PubMed ID: 11786556 | Fulltext

A novel membrane potential-sensitive fluorescent dye improves cell-based assays for ion channels.

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Baxter DF, Kirk M, Garcia AF, Raimondi A, Holmqvist MH, Flint KK, Bojanic D, Distefano PS, Curtis R, and Xie Y

Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening 7(1):79-85, 2002 Feb - Who cited this? | PubMed ID: 11897058 | Fulltext

Elimination of fast inactivation in Kv4 A-type potassium channels by an auxiliary subunit domain.

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Holmqvist MH, Cao J, Hernandez-Pineda R, Jacobson MD, Carroll KI, Sung MA, Betty M, Ge P, Gilbride KJ, Brown ME, Jurman ME, Lawson D, Silos-Santiago I, Xie Y, Covarrubias M, Rhodes KJ,

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Proceedings of the National Academy of Sciences of the United States of America 99(2):1035-40, 2002 Jan 22 - Who cited this? | PubMed ID: 11805342 | Fulltext

Reduced Ia-afferent-mediated Hoffman reflex in streptozotocin-induced diabetic rats.

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Tonra JR, Cliffer KD, Carson SR, Lindsay RM, Bodine SC, and DiStefano PS

Experimental neurology 172(1):220-7, 2001 Nov - Who cited this? | PubMed ID: 11681854 | Fulltext

Differential modulation of sodium channel gating and persistent sodium currents by the beta1, beta2, and beta3 subunits.

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Qu Y, Curtis R, Lawson D, Gilbride K, Ge P, DiStefano PS, Silos-Santiago I, Catterall WA, and Scheuer T

Molecular and cellular neurosciences 18(5):570-80, 2001 Nov - Who cited this? | PubMed ID: 11922146 | Fulltext

A prosurvival function for the p75 receptor death domain mediated via the caspase recruitment domain receptor-interacting protein 2.

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Khursigara G, Bertin J, Yano H, Moffett H, DiStefano PS, and Chao MV

The Journal of neuroscience : the official journal of the Society for Neuroscience 21(16):5854-63, 2001 Aug 15 - Who cited this? | PubMed ID: 11487608 | Fulltext

Neurotrophin-3 is required for the survival-differentiation of subsets of developing enteric neurons.

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Chalazonitis A, Pham TD, Rothman TP, DiStefano PS, Bothwell M, Blair-Flynn J, Tessarollo L, and Gershon MD

The Journal of neuroscience : the official journal of the Society for Neuroscience 21(15):5620-36, 2001 Aug 1 - Who cited this? | PubMed ID: 11466433 | Fulltext

CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri.

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Girardin SE, Tournebize R, Mavris M, Page AL, Li X, Stark GR, Bertin J, DiStefano PS, Yaniv M, Sansonetti PJ, and Philpott DJ

EMBO reports 2(8):736-42, 2001 Aug - Who cited this? | PubMed ID: 11463746 | Fulltext

Card10 is a novel caspase recruitment domain/membrane-associated guanylate kinase family member that interacts with BCL10 and activates NF-kappa B.

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Wang L, Guo Y, Huang WJ, Ke X, Poyet JL, Manji GA, Merriam S, Glucksmann MA, DiStefano PS, Alnemri ES, and Bertin J

The Journal of biological chemistry 276(24):21405-9, 2001 Jun 15 - Who cited this? | PubMed ID: 11259443 | Fulltext

Kinetic modulation of Kv4-mediated A-current by arachidonic acid is dependent on potassium channel interacting proteins.

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Holmqvist MH, Cao J, Knoppers MH, Jurman ME, Distefano PS, Rhodes KJ, Xie Y, and An WF

The Journal of neuroscience : the official journal of the Society for Neuroscience 21(12):4154-61, 2001 Jun 15 - Who cited this? | PubMed ID: 11404400 | Fulltext

Human CARD12 is a novel CED4/Apaf-1 family member that induces apoptosis.

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Geddes BJ, Wang L, Huang WJ, Lavellee M, Manji GA, Brown M, Jurman M, Cao J, Morgenstern J, Merriam S, Glucksmann MA, DiStefano PS, and Bertin J

Biochemical and biophysical research communications 284(1):77-82, 2001 Jun 1 - Who cited this? | PubMed ID: 11374873 | Fulltext

CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane-associated guanylate kinase (MAGUK) family members that interact with BCL10 and activate NF-kappa B.

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Bertin J, Wang L, Guo Y, Jacobson MD, Poyet JL, Srinivasula SM, Merriam S, DiStefano PS, and Alnemri ES

The Journal of biological chemistry 276(15):11877-82, 2001 Apr 13 - Who cited this? | PubMed ID: 11278692 | Fulltext

An orchestrated gene expression component of neuronal programmed cell death revealed by cDNA array analysis.

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Chiang LW, Grenier JM, Ettwiller L, Jenkins LP, Ficenec D, Martin J, Jin F, DiStefano PS, and Wood A

Proceedings of the National Academy of Sciences of the United States of America 98(5):2814-9, 2001 Feb 27 - Who cited this? | PubMed ID: 11226323 | Fulltext

CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-kappa B.

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Bertin J, Guo Y, Wang L, Srinivasula SM, Jacobson MD, Poyet JL, Merriam S, Du MQ, Dyer MJ, Robison KE, DiStefano PS, and Alnemri ES

The Journal of biological chemistry 275(52):41082-6, 2000 Dec 29 - Who cited this? | PubMed ID: 11053425 | Fulltext

The PYRIN domain: a novel motif found in apoptosis and inflammation proteins.

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Bertin J and DiStefano PS

Cell death and differentiation 7(12):1273-4, 2000 Dec - Who cited this? | PubMed ID: 11270363 | Fulltext

Truncated TrkB mediates the endocytosis and release of BDNF and neurotrophin-4/5 by rat astrocytes and schwann cells in vitro.

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Alderson RF, Curtis R, Alterman AL, Lindsay RM, and DiStefano PS

Brain research 871(2):210-22, 2000 Jul 21 - Who cited this? | PubMed ID: 10899288 | Fulltext

A novel nervous system beta subunit that downregulates human large conductance calcium-dependent potassium channels.

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Weiger TM, Holmqvist MH, Levitan IB, Clark FT, Sprague S, Huang WJ, Ge P, Wang C, Lawson D, Jurman ME, Glucksmann MA, Silos-Santiago I, DiStefano PS, and Curtis R

The Journal of neuroscience : the official journal of the Society for Neuroscience 20(10):3563-70, 2000 May 15 - Who cited this? | PubMed ID: 10804197 | Fulltext

Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-kappaB.

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Bertin J, Nir WJ, Fischer CM, Tayber OV, Errada PR, Grant JR, Keilty JJ, Gosselin ML, Robison KE, Wong GH, Glucksmann MA, and DiStefano PS

The Journal of biological chemistry 274(19):12955-8, 1999 May 7 - Who cited this? | PubMed ID: 10224040 | Fulltext

Decreased accumulation of endogenous brain-derived neurotrophic factor against constricting sciatic nerve ligatures in streptozotocin-diabetic and galactose-fed rats.

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Mizisin AP, DiStefano PS, Liu X, Garrett DN, and Tonra JR

Neuroscience letters 263(2-3):149-52, 1999 Mar 26 - Who cited this? | PubMed ID: 10213157 | Fulltext

Consistent repeated M- and H-Wave recording in the hind limb of rats.

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Cliffer KD, Tonra JR, Carson SR, Radley HE, Cavnor C, Lindsay RM, Bodine SC, and DiStefano PS

Muscle & nerve 21(11):1405-13, 1998 Nov - Who cited this? | PubMed ID: 9771663 | Fulltext

Neurotrophin trafficking by anterograde transport.

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Altar CA and DiStefano PS

Trends in neurosciences 21(10):433-7, 1998 Oct - Who cited this? | PubMed ID: 9786341 | Fulltext

Neuronal injury increases retrograde axonal transport of the neurotrophins to spinal sensory neurons and motor neurons via multiple receptor mechanisms.

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Curtis R, Tonra JR, Stark JL, Adryan KM, Park JS, Cliffer KD, Lindsay RM, and DiStefano PS

Molecular and cellular neurosciences 12(3):105-18, 1998 Oct - Who cited this? | PubMed ID: 9790733 | Fulltext

NT-3 attenuates functional and structural disorders in sensory nerves of galactose-fed rats.

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Mizisin AP, Kalichman MW, Bache M, Dines KC, and DiStefano PS

Journal of neuropathology and experimental neurology 57(9):803-13, 1998 Sep - Who cited this? | PubMed ID: 9737543 | Fulltext

Increased expression of CNTF receptor alpha in denervated human skeletal muscle.

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Weis J, Lie DC, Ragoss U, Züchner SL, Schröder JM, Karpati G, Farruggella T, Stahl N, Yancopoulos GD, and DiStefano PS

Journal of neuropathology and experimental neurology 57(9):850-7, 1998 Sep - Who cited this? | PubMed ID: 9737548 | Fulltext

Localization and regulation of MuSK at the neuromuscular junction.

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Bowen DC, Park JS, Bodine S, Stark JL, Valenzuela DM, Stitt TN, Yancopoulos GD, Lindsay RM, Glass DJ, and DiStefano PS

Developmental biology 199(2):309-19, 1998 Jul 15 - Who cited this? | PubMed ID: 9698449 | Fulltext

Co-infusion with a TrkB-Fc receptor body carrier enhances BDNF distribution in the adult rat brain.

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Croll SD, Chesnutt CR, Rudge JS, Acheson A, Ryan TE, Siuciak JA, DiStefano PS, Wiegand SJ, and Lindsay RM

Experimental neurology 152(1):20-33, 1998 Jul - Who cited this? | PubMed ID: 9682009 | Fulltext

Axotomy upregulates the anterograde transport and expression of brain-derived neurotrophic factor by sensory neurons.

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Tonra JR, Curtis R, Wong V, Cliffer KD, Park JS, Timmes A, Nguyen T, Lindsay RM, Acheson A, and DiStefano PS

The Journal of neuroscience : the official journal of the Society for Neuroscience 18(11):4374-83, 1998 Jun 1 - Who cited this? | PubMed ID: 9592114 | Fulltext

A splice variant of trkB and brain-derived neurotrophic factor are co-expressed in retinal pigmented epithelial cells and promote differentiated characteristics.

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Hackett SF, Friedman Z, Freund J, Schoenfeld C, Curtis R, DiStefano PS, and Campochiaro PA

Brain research 789(2):201-12, 1998 Apr 13 - Who cited this? | PubMed ID: 9573364 | Fulltext

Axonal transport of neurotrophins by visceral afferent and efferent neurons of the vagus nerve of the rat.

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Helke CJ, Adryan KM, Fedorowicz J, Zhuo H, Park JS, Curtis R, Radley HE, and Distefano PS

The Journal of comparative neurology 393(1):102-17, 1998 Mar 30 - Who cited this? | PubMed ID: 9520105 | Fulltext

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