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Papers authored by Dinauer MC

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Characterization of P-Rex1 for its role in fMet-Leu-Phe-induced superoxide production in reconstituted COS(phox) cells.

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Nie B, Cheng N, Dinauer MC, and Ye RD

Cellular signalling 22(5):770-82, 2010 May - Who cited this? | PubMed ID: 20074642 | Fulltext

Genetic and cellular evidence of vascular inflammation in neurofibromin-deficient mice and humans.

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Lasater EA, Li F, Bessler WK, Estes ML, Vemula S, Hingtgen CM, Dinauer MC, Kapur R, Conway SJ, and Ingram DA

The Journal of clinical investigation 120(3):859-70, 2010 Mar 1 - Who cited this? | PubMed ID: 20160346 | Fulltext

Phosphorylation of p22phox on Threonine 147 Enhances NADPH Oxidase Activity by Promoting p47phox Binding.

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Lewis EM, Sergeant S, Ledford B, Stull N, Dinauer MC, and McPhail LC

The Journal of biological chemistry 285(5):2959-67, 2010 Jan 29 - Who cited this? | PubMed ID: 19948736 | Fulltext

Retroviral vector integration in post-transplant hematopoiesis in mice conditioned with either submyeloablative or ablative irradiation.

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Sadat MA, Dirscherl S, Sastry L, Dantzer J, Pech N, Griffin S, Hawkins T, Zhao Y, Barese CN, Cross S, Orazi A, An C, Goebel WS, Yoder MC, Li X, Grez M,

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Gene therapy 16(12):1452-64, 2009 Dec - Who cited this? | PubMed ID: 19657370 | Fulltext

A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40 phox and selective defects in neutrophil NADPH oxidase activity.

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Matute JD, Arias AA, Wright NA, Wrobel I, Waterhouse CC, Li XJ, Marchal CC, Stull ND, Lewis DB, Steele M, Kellner JD, Yu W, Meroueh SO, Nauseef WM, and Dinauer MC

Blood 114(15):3309-15, 2009 Oct 8 - Who cited this? | PubMed ID: 19692703 | Fulltext

Activation of antibacterial autophagy by NADPH oxidases.

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Huang J, Canadien V, Lam GY, Steinberg BE, Dinauer MC, Magalhaes MA, Glogauer M, Grinstein S, and Brumell JH

Proceedings of the National Academy of Sciences of the United States of America 106(15):6226-31, 2009 Apr 14 - Who cited this? | PubMed ID: 19339495 | Fulltext

Suppressed hindlimb perfusion in Rac2-/- and Nox2-/- mice does not result from impaired collateral growth.

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Distasi MR, Case J, Ziegler MA, Dinauer MC, Yoder MC, Haneline LS, Dalsing MC, Miller SJ, Labarrere CA, Murphy MP, Ingram DA, and Unthank JL

American journal of physiology. Heart and circulatory physiology 296(3):H877-86, 2009 Mar - Who cited this? | PubMed ID: 19151256 | Fulltext

A fluorescently tagged C-terminal fragment of p47phox detects NADPH oxidase dynamics during phagocytosis.

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Li XJ, Tian W, Stull ND, Grinstein S, Atkinson S, and Dinauer MC

Molecular biology of the cell 20(5):1520-32, 2009 Mar - Who cited this? | PubMed ID: 19129478 | Fulltext

Macrophage NADPH oxidase flavocytochrome B localizes to the plasma membrane and rab11-positive recycling endosomes.

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Casbon AJ, Allen LA, Dunn KW, and Dinauer MC

Journal of immunology (Baltimore, Md. : 1950) 182(4):2325-39, 2009 Feb 15 - Who cited this? | PubMed ID: 19201887 | Fulltext

Mutational analysis reveals distinct features of the Nox4-p22phox complex.

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von Lohneysen K, Noack D, Jesaitis AJ, Dinauer MC, and Knaus UG

The Journal of biological chemistry, 2008 Oct 10 - Who cited this? | PubMed ID: 18849343 | Fulltext

Fc{gamma}R-stimulated activation of the NADPH oxidase: Phosphoinositide binding protein p40phox regulates NADPH oxidase activity after enzyme assembly on the phagosome.

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Tian W, Li XJ, Stull ND, Ming W, Suh CI, Bissonnette SA, Yaffe MB, Grinstein S, Atkinson SJ, and Dinauer MC

Blood, 2008 Aug 18 - Who cited this? | PubMed ID: 18711001 | Fulltext

The role of Rac2 in regulating neutrophil production in the bone marrow and circulating neutrophil counts.

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Gomez JC, Soltys J, Okano K, Dinauer MC, and Doerschuk CM

The American journal of pathology 173(2):507, 2008 Aug - Who cited this? | PubMed ID: 18583316 | Fulltext

Automated analysis of viral integration sites in gene therapy research using the SeqMap web resource.

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Peters B, Dirscherl S, Dantzer J, Nowacki J, Cross S, Li X, Cornetta K, Dinauer MC, and Mooney SD

Gene therapy, 2008 Jun 26 - Who cited this? | PubMed ID: 18580967 | Fulltext

Neutrophil caveolin-1 expression contributes to mechanism of lung inflammation and injury.

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Hu G, Ye RD, Dinauer MC, Malik AB, and Minshall RD

American journal of physiology. Lung cellular and molecular physiology 294(2):L178-86, 2008 Feb - Who cited this? | PubMed ID: 17993589 | Fulltext

Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins.

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Li Y, Yan J, De P, Chang HC, Yamauchi A, Christopherson KW, Paranavitana NC, Peng X, Kim C, Munugalavadla V, Kapur R, Chen H, Shou W, Stone JC, Kaplan MH, Dinauer MC,

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Journal of immunology (Baltimore, Md. : 1950) 179(12):8322, 2007 Dec 15 - Who cited this? | PubMed ID: 18056377 | Fulltext

Mutations of the ELA2 gene found in patients with severe congenital neutropenia induce the unfolded protein response and cellular apoptosis.

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Grenda DS, Murakami M, Ghatak J, Xia J, Boxer LA, Dale D, Dinauer MC, and Link DC

Blood 110(13):4179, 2007 Dec 15 - Who cited this? | PubMed ID: 17761833 | Fulltext

A critical role of protein kinase C delta activation loop phosphorylation in formyl-methionyl-leucyl-phenylalanine-induced phosphorylation of p47(phox) and rapid activation of nicotinamide adenine dinucleotide phosphate oxidase.

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Cheng N, He R, Tian J, Dinauer MC, and Ye RD

Journal of immunology (Baltimore, Md. : 1950) 179(11):7720, 2007 Dec 1 - Who cited this? | PubMed ID: 18025218 | Fulltext

Characterization of a mutation in the Phox homology domain of the NADPH oxidase component p40phox identifies a mechanism for negative regulation of superoxide production.

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Chen J, He R, Minshall RD, Dinauer MC, and Ye RD

The Journal of biological chemistry 282(41):30273-84, 2007 Oct 12 - Who cited this? | PubMed ID: 17698849 | Fulltext

Aberrant regulation of hematopoiesis by T cells in BAZF-deficient mice.

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Broxmeyer HE, Sehra S, Cooper S, Toney LM, Kusam S, Aloor JJ, Marchal CC, Dinauer MC, and Dent AL

Molecular and cellular biology 27(15):5275-85, 2007 Aug - Who cited this? | PubMed ID: 17526724 | Fulltext

Granulocyte colony-stimulating factor prior to nonmyeloablative irradiation decreases murine host hematopoietic stem cell function and increases engraftment of donor marrow cells.

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Barese C, Pech N, Dirscherl S, Meyers JL, Sinn AL, Yoder MC, Goebel WS, and Dinauer MC

Stem cells (Dayton, Ohio) 25(6):1578-85, 2007 Jun - Who cited this? | PubMed ID: 17347493 | Fulltext

Critical roles for p22phox in the structural maturation and subcellular targeting of Nox3.

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Nakano Y, Banfi B, Jesaitis AJ, Dinauer MC, Allen LA, and Nauseef WM

The Biochemical journal 403(1):97-108, 2007 Apr 1 - Who cited this? | PubMed ID: 17140397 | Fulltext

The Rac effector p67phox regulates phagocyte NADPH oxidase by stimulating Vav1 guanine nucleotide exchange activity.

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Ming W, Li S, Billadeau DD, Quilliam LA, and Dinauer MC

Molecular and cellular biology 27(1):312-23, 2007 Jan - Who cited this? | PubMed ID: 17060455 | Fulltext

Disorders of neutrophil function: an overview.

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Dinauer MC

Methods in molecular biology (Clifton, N.J.) 412:489-504, 2007 - Who cited this? | PubMed ID: 18453130 | Fulltext

Deletion mutagenesis of p22phox subunit of flavocytochrome b558: identification of regions critical for gp91phox maturation and NADPH oxidase activity.

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Zhu Y, Marchal CC, Casbon AJ, Stull N, von Löhneysen K, Knaus UG, Jesaitis AJ, McCormick S, Nauseef WM, and Dinauer MC

The Journal of biological chemistry 281(41):30336-46, 2006 Oct 13 - Who cited this? | PubMed ID: 16895900 | Fulltext

The C-terminal flavin domain of gp91phox bound to plasma membranes of granulocyte-like X-CGD PLB-985 cells is sufficient to anchor cytosolic oxidase components and support NADPH oxidase-associated diaphorase activity independent of cytosolic phospholipase A2 regulation.

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Pessach I, Shmelzer Z, Leto TL, Dinauer MC, and Levy R

Journal of leukocyte biology 80(3):630-9, 2006 Sep - Who cited this? | PubMed ID: 16844764 | Fulltext

The phosphoinositide-binding protein p40phox activates the NADPH oxidase during FcgammaIIA receptor-induced phagocytosis.

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Suh CI, Stull ND, Li XJ, Tian W, Price MO, Grinstein S, Yaffe MB, Atkinson S, and Dinauer MC

The Journal of experimental medicine 203(8):1915-25, 2006 Aug 7 - Who cited this? | PubMed ID: 16880255 | Fulltext

The role of nicotinamide adenine dinucleotide phosphate oxidase-derived reactive oxygen species in the acquisition of metastatic ability of tumor cells.

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Okada F, Kobayashi M, Tanaka H, Kobayashi T, Tazawa H, Iuchi Y, Onuma K, Hosokawa M, Dinauer MC, and Hunt NH

The American journal of pathology 169(1):294-302, 2006 Jul - Who cited this? | PubMed ID: 16816381 | Fulltext

Impaired NADPH oxidase activity in Rac2-deficient murine neutrophils does not result from defective translocation of p47phox and p67phox and can be rescued by exogenous arachidonic acid.

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Kim C and Dinauer MC

Journal of leukocyte biology 79(1):223, 2006 Jan - Who cited this? | PubMed ID: 16275890 | Fulltext

Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases.

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Martyn KD, Frederick LM, von Loehneysen K, Dinauer MC, and Knaus UG

Cellular signalling 18(1):69-82, 2006 Jan - Who cited this? | PubMed ID: 15927447 | Fulltext

Rac2 concentrations in umbilical cord neutrophils.

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Meade VM, Barese CN, Kim C, Njinimbam CG, Marchal CC, Ingram DA, Clapp DW, Dinauer MC, and Yoder MC

Biology of the neonate 90(3):156-9, 2006 - Who cited this? | PubMed ID: 16582540 | Fulltext

p21-activated kinase (Pak) regulates NADPH oxidase activation in human neutrophils.

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Martyn KD, Kim MJ, Quinn MT, Dinauer MC, and Knaus UG

Blood 106(12):3962-9, 2005 Dec 1 - Who cited this? | PubMed ID: 16099876 | Fulltext

Gene correction reduces cutaneous inflammation and granuloma formation in murine X-linked chronic granulomatous disease.

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Goebel WS, Mark LA, Billings SD, Meyers JL, Pech N, Travers JB, and Dinauer MC

The Journal of investigative dermatology 125(4):705, 2005 Oct - Who cited this? | PubMed ID: 16185269 | Fulltext

Newly diagnosed chronic granulomatous disease in a 53-year-old woman with Crohn disease.

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Ramanuja S, Wolf KM, Sadat MA, Mahoney SJ, Dinauer MC, and Nelson RP

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 95(2):204-9, 2005 Aug - Who cited this? | PubMed ID: 16136772 | Fulltext

Rac2 regulates neutrophil chemotaxis, superoxide production, and myeloid colony formation through multiple distinct effector pathways.

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Carstanjen D, Yamauchi A, Koornneef A, Zang H, Filippi MD, Harris C, Towe J, Atkinson S, Zheng Y, Dinauer MC, and Williams DA

Journal of immunology (Baltimore, Md. : 1950) 174(8):4613, 2005 Apr 15 - Who cited this? | PubMed ID: 15814684 | Fulltext

Monoclonal antibody CL5 recognizes the amino terminal domain of human phagocyte flavocytochrome b558 large subunit, gp91phox.

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Baniulis D, Burritt JB, Taylor RM, Dinauer MC, Heyworth PG, Parkos CA, Magnusson KE, and Jesaitis AJ

European journal of haematology 74(4):337-47, 2005 Apr - Who cited this? | PubMed ID: 15777347 | Fulltext

Unusual polyclonal anti-gp91 peptide antibody interactions with X-linked chronic granulomatous disease-derived human neutrophils are not from compensatory expression of Nox proteins 1, 3, or 4.

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Baniulis D, Nauseef WM, Burritt JB, Taylor RM, Heyworth PG, Dinauer MC, Bumelis VA, Magnusson KE, and Jesaitis AJ

European journal of haematology 74(3):241-9, 2005 Mar - Who cited this? | PubMed ID: 15693794 | Fulltext

Rac GTPase isoform-specific regulation of NADPH oxidase and chemotaxis in murine neutrophils in vivo. Role of the C-terminal polybasic domain.

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Yamauchi A, Marchal CC, Molitoris J, Pech N, Knaus U, Towe J, Atkinson SJ, and Dinauer MC

The Journal of biological chemistry 280(2):953-64, 2005 Jan 14 - Who cited this? | PubMed ID: 15504745 | Fulltext

p40phox: the last NADPH oxidase subunit.

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Matute JD, Arias AA, Dinauer MC, and Patiño PJ

Blood cells, molecules & diseases 35(2):291-302, 2005 - Who cited this? | PubMed ID: 16102984 | Fulltext

Chronic granulomatous disease and other disorders of phagocyte function.

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Dinauer MC

Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program:89-95, 2005 - Who cited this? | PubMed ID: 16304364 | Fulltext

Site-specific inhibitors of NADPH oxidase activity and structural probes of flavocytochrome b: characterization of six monoclonal antibodies to the p22phox subunit.

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Taylor RM, Burritt JB, Baniulis D, Foubert TR, Lord CI, Dinauer MC, Parkos CA, and Jesaitis AJ

Journal of immunology (Baltimore, Md. : 1950) 173(12):7349-57, 2004 Dec 15 - Who cited this? | PubMed ID: 15585859 | Fulltext

Reconstitution of chemotactic peptide-induced nicotinamide adenine dinucleotide phosphate (reduced) oxidase activation in transgenic COS-phox cells.

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He R, Nanamori M, Sang H, Yin H, Dinauer MC, and Ye RD

Journal of immunology (Baltimore, Md. : 1950) 173(12):7462-70, 2004 Dec 15 - Who cited this? | PubMed ID: 15585872 | Fulltext

A murine model of antimetabolite-based, submyeloablative conditioning for bone marrow transplantation: biologic insights and potential applications.

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Goebel WS, Pech NK, Meyers JL, Srour EF, Yoder MC, and Dinauer MC

Experimental hematology 32(12):1255, 2004 Dec - Who cited this? | PubMed ID: 15588950 | Fulltext

Rac2-deficient murine macrophages have selective defects in superoxide production and phagocytosis of opsonized particles.

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Yamauchi A, Kim C, Li S, Marchal CC, Towe J, Atkinson SJ, and Dinauer MC

Journal of immunology (Baltimore, Md. : 1950) 173(10):5971, 2004 Nov 15 - Who cited this? | PubMed ID: 15528331 | Fulltext

Stable long-term gene correction with low-dose radiation conditioning in murine X-linked chronic granulomatous disease.

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Goebel WS, Pech NK, and Dinauer MC

Blood cells, molecules & diseases 33(3):365 - Who cited this? | PubMed ID: 15528159 | Fulltext

Mitochondrial transmembrane potential is diminished in phorbol myristate acetate-stimulated peritoneal resident macrophages isolated from wild-type mice, but not in those from gp91-phox-deficient mice.

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Kobayashi T, Ogawa Y, Watanabe Y, Furuya M, Kataoka S, Garcia del Saz E, Tsunawaki S, Dinauer MC, and Seguchi H

Histochemistry and cell biology 122(4):323-32, 2004 Oct - Who cited this? | PubMed ID: 15243751 | Fulltext

In vivo role of myeloperoxidase for the host defense.

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Aratani Y, Kura F, Watanabe H, Akagawa H, Takano Y, Suzuki K, Dinauer MC, Maeda N, and Koyama H

Japanese journal of infectious diseases 57(5):S15, 2004 Oct - Who cited this? | PubMed ID: 15507755 | Fulltext

Gene therapy for chronic granulomatous disease.

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Barese CN, Goebel WS, and Dinauer MC

Expert opinion on biological therapy 4(9):1423-34, 2004 Sep - Who cited this? | PubMed ID: 15335310 | Fulltext

[Expression and activity of polymorphisms in the 67-kDa protein of the NADPH oxidase system].

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Arias AA, Dinauer MC, Ding J, Matute JD, and Patiño PJ

Biomedica : revista del Instituto Nacional de Salud 24(3):262-72, 2004 Sep - Who cited this? | PubMed ID: 15551878 | Fulltext

Rac2 is critical for neutrophil primary granule exocytosis.

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Abdel-Latif D, Steward M, Macdonald DL, Francis GA, Dinauer MC, and Lacy P

Blood 104(3):832-9, 2004 Aug 1 - Who cited this? | PubMed ID: 15073033 | Fulltext

Antagonistic cross-talk between Rac and Cdc42 GTPases regulates generation of reactive oxygen species.

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Diebold BA, Fowler B, Lu J, Dinauer MC, and Bokoch GM

The Journal of biological chemistry 279(27):28136-42, 2004 Jul 2 - Who cited this? | PubMed ID: 15123662 | Fulltext

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