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Papers authored by Dickson JK

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Discovery and structure-activity relationships of trisubstituted pyrimidines/pyridines as novel calcium-sensing receptor antagonists.

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Yang W, Ruan Z, Wang Y, Van Kirk K, Ma Z, Arey BJ, Cooper CB, Seethala R, Feyen JH, and Dickson JK

Journal of medicinal chemistry 52(4):1204-8, 2009 Feb 26 - Who cited this? | PubMed ID: 19143533 | Fulltext

Design and synthesis of a g-protein-coupled receptor antagonist library of aryloxyalkanolamines using a polymer-supported acyclic acetal linker.

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Roberge JY, Harikrishnan LS, Kamau MG, Ruan Z, Van Kirk K, Liu Y, Cooper CB, Poss MA, Dickson JK, Gavai AV, Chao ST, Leith LW, Bednarz MS, Mathur A, Kakarla R, Schnur DM,

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Journal of combinatorial chemistry 11(1):72-82, 2009 - Who cited this? | PubMed ID: 19086798 | Fulltext

High throughput screening identified a substituted imidazole as a novel RANK pathway-selective osteoclastogenesis inhibitor.

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Chen T, Knapp AC, Wu Y, Huang J, Lynch JS, Dickson JK, Lawrence RM, Feyen JH, and Agler ML

Assay and drug development technologies 4(4):387-96, 2006 Aug - Who cited this? | PubMed ID: 16945012 | Fulltext

Synthesis and characterization of 3-arylquinazolinone and 3-arylquinazolinethione derivatives as selective estrogen receptor beta modulators.

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Güngör T, Chen Y, Golla R, Ma Z, Corte JR, Northrop JP, Bin B, Dickson JK, Stouch T, Zhou R, Johnson SE, Seethala R, and Feyen JH

Journal of medicinal chemistry 49(8):2440-55, 2006 Apr 20 - Who cited this? | PubMed ID: 16610787 | Fulltext

Discovery of novel 1-arylmethyl pyrrolidin-2-yl ethanol amines as calcium-sensing receptor antagonists.

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Gavai AV, Vaz RJ, Mikkilineni AB, Roberge JY, Liu Y, Lawrence RM, Corte JR, Yang W, Bednarz M, Dickson JK, Ma Z, Seethala R, and Feyen JH

Bioorganic & medicinal chemistry letters 15(24):5478-82, 2005 Dec 15 - Who cited this? | PubMed ID: 16216508 | Fulltext

A novel calcium-sensing receptor antagonist transiently stimulates parathyroid hormone secretion in vivo.

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Arey BJ, Seethala R, Ma Z, Fura A, Morin J, Swartz J, Vyas V, Yang W, Dickson JK, and Feyen JH

Endocrinology 146(4):2015-22, 2005 Apr - Who cited this? | PubMed ID: 15637285 | Fulltext

Discovery and structure-activity relationships of 2-benzylpyrrolidine-substituted aryloxypropanols as calcium-sensing receptor antagonists.

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Yang W, Wang Y, Roberge JY, Ma Z, Liu Y, Michael Lawrence R, Rotella DP, Seethala R, Feyen JH, and Dickson JK

Bioorganic & medicinal chemistry letters 15(4):1225-8, 2005 Feb 15 - Who cited this? | PubMed ID: 15686947 | Fulltext

Discovery of highly selective inhibitors of p38alpha.

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Popa-Burke I, Birkos S, Blackwell L, Cheatham L, Clark J, Dickson JK, Galasinski S, Janzen WP, Mendoza J, Miller JL, Mohney RP, Steed PM, and Hodge CN

Current topics in medicinal chemistry 5(10):941-51, 2005 - Who cited this? | PubMed ID: 16178739 | Fulltext

Synthesis and structure-activity relationship of 3-arylbenzoxazines as selective estrogen receptor beta agonists.

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Yang W, Wang Y, Ma Z, Golla R, Stouch T, Seethala R, Johnson S, Zhou R, Güngör T, Feyen JH, and Dickson JK

Bioorganic & medicinal chemistry letters 14(9):2327-30, 2004 May 3 - Who cited this? | PubMed ID: 15081034 | Fulltext

Characterization of a new class of selective nonsteroidal progesterone receptor agonists.

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Dong Y, Roberge JY, Wang Z, Wang X, Tamasi J, Dell V, Golla R, Corte JR, Liu Y, Fang T, Anthony MN, Schnur DM, Agler ML, Dickson JK, Lawrence RM, Prack MM,

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Steroids 69(3):201-17, 2004 Mar - Who cited this? | PubMed ID: 15072922 | Fulltext

Microsomal triglyceride transfer protein inhibitors: discovery and synthesis of alkyl phosphonates as potent MTP inhibitors and cholesterol lowering agents.

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Magnin DR, Biller SA, Wetterau J, Robl JA, Dickson JK, Taunk P, Harrity TW, Lawrence RM, Sun CQ, Wang T, Logan J, Fryszman O, Connolly F, Jolibois K, and Kunselman L

Bioorganic & medicinal chemistry letters 13(7):1337-40, 2003 Apr 7 - Who cited this? | PubMed ID: 12657277 | Fulltext

A novel series of highly potent benzimidazole-based microsomal triglyceride transfer protein inhibitors.

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Robl JA, Sulsky R, Sun CQ, Simpkins LM, Wang T, Dickson JK, Chen Y, Magnin DR, Taunk P, Slusarchyk WA, Biller SA, Lan SJ, Connolly F, Kunselman LK, Sabrah T, Jamil H,

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Journal of medicinal chemistry 44(6):851-6, 2001 Mar 15 - Who cited this? | PubMed ID: 11300866 | Fulltext

An MTP inhibitor that normalizes atherogenic lipoprotein levels in WHHL rabbits.

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Wetterau JR, Gregg RE, Harrity TW, Arbeeny C, Cap M, Connolly F, Chu CH, George RJ, Gordon DA, Jamil H, Jolibois KG, Kunselman LK, Lan SJ, Maccagnan TJ, Ricci B, Yan M,

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Science (New York, N.Y.) 282(5389):751-4, 1998 Oct 23 - Who cited this? | PubMed ID: 9784135 | Fulltext

Evidence that microsomal triglyceride transfer protein is limiting in the production of apolipoprotein B-containing lipoproteins in hepatic cells.

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Jamil H, Chu CH, Dickson JK, Chen Y, Yan M, Biller SA, Gregg RE, Wetterau JR, and Gordon DA

Journal of lipid research 39(7):1448-54, 1998 Jul - Who cited this? | PubMed ID: 9684748 | Fulltext

An inhibitor of the microsomal triglyceride transfer protein inhibits apoB secretion from HepG2 cells.

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Jamil H, Gordon DA, Eustice DC, Brooks CM, Dickson JK, Chen Y, Ricci B, Chu CH, Harrity TW, Ciosek CP, Biller SA, Gregg RE, and Wetterau JR

Proceedings of the National Academy of Sciences of the United States of America 93(21):11991-5, 1996 Oct 15 - Who cited this? | PubMed ID: 8876250 | Fulltext

alpha-Phosphonosulfonic acids: potent and selective inhibitors of squalene synthase.

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Magnin DR, Biller SA, Chen Y, Dickson JK, Fryszman OM, Lawrence RM, Logan JV, Sieber-McMaster ES, Sulsky RB, Traeger SC, Hsieh DC, Lan SJ, Rinehart JK, Harrity TW, Jolibois KG, Kunselman LK,

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Journal of medicinal chemistry 39(3):657-60, 1996 Feb 2 - Who cited this? | PubMed ID: 8576905 | Fulltext

Orally active squalene synthase inhibitors: bis((acyloxy)alkyl) prodrugs of the alpha-phosphonosulfonic acid moiety.

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Dickson JK, Biller SA, Magnin DR, Petrillo EW, Hillyer JW, Hsieh DC, Lan SJ, Rinehart JK, Gregg RE, Harrity TW, Jolibois KG, Kalinowski SS, Kunselman LK, Mookhtiar KA, and Ciosek CP

Journal of medicinal chemistry 39(3):661-4, 1996 Feb 2 - Who cited this? | PubMed ID: 8576906 | Fulltext

1,1-Bisphosphonate squalene synthase inhibitors: interplay between the isoprenoid subunit and the diphosphate surrogate.

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Magnin DR, Biller SA, Dickson JK, Logan JV, Lawrence RM, Chen Y, Sulsky RB, Ciosek CP, Harrity TW, and Jolibois KG

Journal of medicinal chemistry 38(14):2596-605, 1995 Jul 7 - Who cited this? | PubMed ID: 7629799 | Fulltext

Microsomal triglyceride transfer protein. Specificity of lipid binding and transport.

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Jamil H, Dickson JK, Chu CH, Lago MW, Rinehart JK, Biller SA, Gregg RE, and Wetterau JR

The Journal of biological chemistry 270(12):6549-54, 1995 Mar 24 - Who cited this? | PubMed ID: 7896791 | Fulltext

Lipophilic 1,1-bisphosphonates are potent squalene synthase inhibitors and orally active cholesterol lowering agents in vivo.

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Ciosek CP, Magnin DR, Harrity TW, Logan JV, Dickson JK, Gordon EM, Hamilton KA, Jolibois KG, Kunselman LK, and Lawrence RM

The Journal of biological chemistry 268(33):24832-7, 1993 Nov 25 - Who cited this? | PubMed ID: 8227045 | Fulltext

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