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Papers authored by Di Tomaso E

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Direct Evidence that Bevacizumab, an Anti-VEGF Antibody, Up-regulates SDF1{alpha}, CXCR4, CXCL6, and Neuropilin 1 in Tumors from Patients with Rectal Cancer.

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Xu L, Duda DG, di Tomaso E, Ancukiewicz M, Chung DC, Lauwers GY, Samuel R, Shellito P, Czito BG, Lin PC, Poleski M, Bentley R, Clark JW, Willett CG, and Jain RK

Cancer research 69(20):7905-10, 2009 Oct 15 - Who cited this? | PubMed ID: 19826039 | Fulltext

Hearing improvement after bevacizumab in patients with neurofibromatosis type 2.

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Plotkin SR, Stemmer-Rachamimov AO, Barker FG, Halpin C, Padera TP, Tyrrell A, Sorensen AG, Jain RK, and di Tomaso E

The New England journal of medicine 361(4):358-67, 2009 Jul 23 - Who cited this? | PubMed ID: 19587327 | Fulltext

A "vascular normalization index" as potential mechanistic biomarker to predict survival after a single dose of cediranib in recurrent glioblastoma patients.

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Sorensen AG, Batchelor TT, Zhang WT, Chen PJ, Yeo P, Wang M, Jennings D, Wen PY, Lahdenranta J, Ancukiewicz M, di Tomaso E, Duda DG, and Jain RK

Cancer research 69(13):5296-300, 2009 Jul 1 - Who cited this? | PubMed ID: 19549889 | Fulltext

Efficacy, safety, and biomarkers of neoadjuvant bevacizumab, radiation therapy, and fluorouracil in rectal cancer: a multidisciplinary phase II study.

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Willett CG, Duda DG, di Tomaso E, Boucher Y, Ancukiewicz M, Sahani DV, Lahdenranta J, Chung DC, Fischman AJ, Lauwers GY, Shellito P, Czito BG, Wong TZ, Paulson E, Poleski M, Vujaskovic Z,

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Journal of clinical oncology : official journal of the American Society of Clinical Oncology 27(18):3020-6, 2009 Jun 20 - Who cited this? | PubMed ID: 19470921 | Fulltext

Efficacy, safety, and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: a phase II study.

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Zhu AX, Sahani DV, Duda DG, di Tomaso E, Ancukiewicz M, Catalano OA, Sindhwani V, Blaszkowsky LS, Yoon SS, Lahdenranta J, Bhargava P, Meyerhardt J, Clark JW, Kwak EL, Hezel AF, Miksad R,

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Journal of clinical oncology : official journal of the American Society of Clinical Oncology 27(18):3027-35, 2009 Jun 20 - Who cited this? | PubMed ID: 19470923 | Fulltext

Edema control by cediranib, a vascular endothelial growth factor receptor-targeted kinase inhibitor, prolongs survival despite persistent brain tumor growth in mice.

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Kamoun WS, Ley CD, Farrar CT, Duyverman AM, Lahdenranta J, Lacorre DA, Batchelor TT, di Tomaso E, Duda DG, Munn LL, Fukumura D, Sorensen AG, and Jain RK

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 27(15):2542-52, 2009 May 20 - Who cited this? | PubMed ID: 19332720 | Fulltext

VEGF inhibitors in the treatment of cerebral edema in patients with brain cancer.

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Gerstner ER, Duda DG, di Tomaso E, Ryg PA, Loeffler JS, Sorensen AG, Ivy P, Jain RK, and Batchelor TT

Nature reviews. Clinical oncology 6(4):229-36, 2009 Apr - Who cited this? | PubMed ID: 19333229 | Fulltext

PDGF-C induces maturation of blood vessels in a model of glioblastoma and attenuates the response to anti-VEGF treatment.

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di Tomaso E, London N, Fuja D, Logie J, Tyrrell JA, Kamoun W, Munn LL, and Jain RK

PLoS ONE 4(4):e5123, 2009 - Who cited this? | PubMed ID: 19352490 | Fulltext

Antiangiogenic agents for the treatment of glioblastoma.

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Gerstner ER, Duda DG, di Tomaso E, Sorensen G, Jain RK, and Batchelor TT

Expert opinion on investigational drugs 16(12):1895-908, 2007 Dec - Who cited this? | PubMed ID: 18041999 | Fulltext

Angiogenesis in brain tumours.

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Jain RK, di Tomaso E, Duda DG, Loeffler JS, Sorensen AG, and Batchelor TT

Nature reviews. Neuroscience 8(8):610-22, 2007 Aug - Who cited this? | PubMed ID: 17643088 | Fulltext

Complete pathological response to bevacizumab and chemoradiation in advanced rectal cancer.

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Willett CG, Duda DG, di Tomaso E, Boucher Y, Czito BG, Vujaskovic Z, Vlahovic G, Bendell J, Cohen KS, Hurwitz HI, Bentley R, Lauwers GY, Poleski M, Wong TZ, Paulson E, Ludwig KA,

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Nature clinical practice. Oncology 4(5):316-21, 2007 May - Who cited this? | PubMed ID: 17464339 | Fulltext

Robust 3-D modeling of vasculature imagery using superellipsoids.

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Tyrrell JA, di Tomaso E, Fuja D, Tong R, Kozak K, Jain RK, and Roysam B

IEEE transactions on medical imaging 26(2):223-37, 2007 Feb - Who cited this? | PubMed ID: 17304736 | Fulltext

AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients.

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Batchelor TT, Sorensen AG, di Tomaso E, Zhang WT, Duda DG, Cohen KS, Kozak KR, Cahill DP, Chen PJ, Zhu M, Ancukiewicz M, Mrugala MM, Plotkin S, Drappatz J, Louis DN, Ivy P,

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Cancer cell 11(1):83, 2007 Jan - Who cited this? | PubMed ID: 17222792 | Fulltext

Platelet-derived growth factor receptor-beta in Gorham's disease.

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Hagendoorn J, Padera TP, Yock TI, Nielsen GP, di Tomaso E, Duda DG, Delaney TF, Gaissert HA, Pearce J, Rosenberg AE, Jain RK, and Ebb DH

Nature clinical practice. Oncology 3(12):693-7, 2006 Dec - Who cited this? | PubMed ID: 17139320 | Fulltext

Combined vascular endothelial growth factor-targeted therapy and radiotherapy for rectal cancer: theory and clinical practice.

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Willett CG, Kozin SV, Duda DG, di Tomaso E, Kozak KR, Boucher Y, and Jain RK

Seminars in oncology 33(5 Suppl 10):S35-40, 2006 Oct - Who cited this? | PubMed ID: 17145523 | Fulltext

Imaging steps of lymphatic metastasis reveals that vascular endothelial growth factor-C increases metastasis by increasing delivery of cancer cells to lymph nodes: therapeutic implications.

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Hoshida T, Isaka N, Hagendoorn J, di Tomaso E, Chen YL, Pytowski B, Fukumura D, Padera TP, and Jain RK

Cancer research 66(16):8065-75, 2006 Aug 15 - Who cited this? | PubMed ID: 16912183 | Fulltext

Differential CD146 expression on circulating versus tissue endothelial cells in rectal cancer patients: implications for circulating endothelial and progenitor cells as biomarkers for antiangiogenic therapy.

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Duda DG, Cohen KS, di Tomaso E, Au P, Klein RJ, Scadden DT, Willett CG, and Jain RK

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 24(9):1449, 2006 Mar 20 - Who cited this? | PubMed ID: 16549839 | Fulltext

Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients.

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Willett CG, Boucher Y, Duda DG, di Tomaso E, Munn LL, Tong RT, Kozin SV, Petit L, Jain RK, Chung DC, Sahani DV, Kalva SP, Cohen KS, Scadden DT, Fischman AJ, Clark JW,

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Journal of clinical oncology : official journal of the American Society of Clinical Oncology 23(31):8136-9, 2005 Nov 1 - Who cited this? | PubMed ID: 16258121 | Fulltext

Mosaic tumor vessels: cellular basis and ultrastructure of focal regions lacking endothelial cell markers.

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di Tomaso E, Capen D, Haskell A, Hart J, Logie JJ, Jain RK, McDonald DM, Jones R, and Munn LL

Cancer research 65(13):5740, 2005 Jul 1 - Who cited this? | PubMed ID: 15994949 | Fulltext

Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases.

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Winkler F, Kozin SV, Tong RT, Chae SS, Booth MF, Garkavtsev I, Xu L, Hicklin DJ, Fukumura D, di Tomaso E, Munn LL, and Jain RK

Cancer cell 6(6):553, 2004 Dec - Who cited this? | PubMed ID: 15607960 | Fulltext

Pathology: cancer cells compress intratumour vessels.

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Padera TP, Stoll BR, Tooredman JB, Capen D, di Tomaso E, and Jain RK

Nature 427(6976):695, 2004 Feb 19 - Who cited this? | PubMed ID: 14973470 | Fulltext

Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer.

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Willett CG, Boucher Y, di Tomaso E, Duda DG, Munn LL, Tong RT, Chung DC, Sahani DV, Kalva SP, Kozin SV, Mino M, Cohen KS, Scadden DT, Hartford AC, Fischman AJ, Clark JW,

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Nature medicine 10(2):145-7, 2004 Feb - Who cited this? | PubMed ID: 14745444 | Fulltext

Responses to antiangiogenesis treatment of spontaneous autochthonous tumors and their isografts.

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Izumi Y, di Tomaso E, Hooper A, Huang P, Huber J, Hicklin DJ, Fukumura D, Jain RK, and Suit HD

Cancer research 63(4):747-51, 2003 Feb 15 - Who cited this? | PubMed ID: 12591719 | Fulltext

Lymphatic metastasis in the absence of functional intratumor lymphatics.

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Padera TP, Kadambi A, di Tomaso E, Carreira CM, Brown EB, Boucher Y, Choi NC, Mathisen D, Wain J, Mark EJ, Munn LL, and Jain RK

Science (New York, N.Y.) 296(5574):1883-6, 2002 Jun 7 - Who cited this? | PubMed ID: 11976409 | Fulltext

Tumour biology: herceptin acts as an anti-angiogenic cocktail.

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Izumi Y, Xu L, di Tomaso E, Fukumura D, and Jain RK

Nature 416(6878):279-80, 2002 Mar 21 - Who cited this? | PubMed ID: 11907566 | Fulltext

LYVE-1 is not restricted to the lymph vessels: expression in normal liver blood sinusoids and down-regulation in human liver cancer and cirrhosis.

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Mouta Carreira C, Nasser SM, di Tomaso E, Padera TP, Boucher Y, Tomarev SI, and Jain RK

Cancer research 61(22):8079-84, 2001 Nov 15 - Who cited this? | PubMed ID: 11719431 | Fulltext

Role of tumor-host interactions in interstitial diffusion of macromolecules: cranial vs. subcutaneous tumors.

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Pluen A, Boucher Y, Ramanujan S, McKee TD, Gohongi T, di Tomaso E, Brown EB, Izumi Y, Campbell RB, Berk DA, and Jain RK

Proceedings of the National Academy of Sciences of the United States of America 98(8):4628-33, 2001 Apr 10 - Who cited this? | PubMed ID: 11274375 | Fulltext

Mosaic blood vessels in tumors: frequency of cancer cells in contact with flowing blood.

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Chang YS, di Tomaso E, McDonald DM, Jones R, Jain RK, and Munn LL

Proceedings of the National Academy of Sciences of the United States of America 97(26):14608-13, 2000 Dec 19 - Who cited this? | PubMed ID: 11121063 | Fulltext

Anti-Vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions.

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Lee CG, Heijn M, di Tomaso E, Griffon-Etienne G, Ancukiewicz M, Koike C, Park KR, Ferrara N, Jain RK, Suit HD, and Boucher Y

Cancer research 60(19):5565-70, 2000 Oct 1 - Who cited this? | PubMed ID: 11034104 | Fulltext

Establishment and characterization of a human cell line from paediatric cerebellar glioblastoma multiforme.

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Di Tomaso E, Pang JC, Lam HK, Tian XX, Suen KW, Hui AB, and Hjelm NM

Neuropathology and applied neurobiology 26(1):22-30, 2000 Feb - Who cited this? | PubMed ID: 10736064 | Fulltext

Expression of p19INK4d, CDK4, CDK6 in glioblastoma multiforme.

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Lam PY, Di Tomaso E, Ng HK, Pang JC, Roussel MF, and Hjelm NM

British journal of neurosurgery 14(1):28-32, 2000 Feb - Who cited this? | PubMed ID: 10884881 | Fulltext

Inhibition of anandamide hydrolysis in rat brain tissue by (E)-6-(bromomethylene) tetrahydro-3-(1-naphthalenyl)-2H-pyran-2-one.

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Beltramo M, di Tomaso E, and Piomelli D

FEBS letters 403(3):263-7, 1997 Feb 24 - Who cited this? | PubMed ID: 9091314 | Fulltext

Occurrence and biosynthesis of endogenous cannabinoid precursor, N-arachidonoyl phosphatidylethanolamine, in rat brain.

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Cadas H, di Tomaso E, and Piomelli D

The Journal of neuroscience : the official journal of the Society for Neuroscience 17(4):1226-42, 1997 Feb 15 - Who cited this? | PubMed ID: 9006968 | Fulltext

Endogenous lipids that activate cannabinoid receptors. Formation and inactivation.

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Di Tomaso E, Cadas H, Gaillet S, Beltramo M, Desarnaud F, Venance L, and Piomelli D

Advances in experimental medicine and biology 407:335-40, 1997 - Who cited this? | PubMed ID: 9321973 | Fulltext

Brain cannabinoids in chocolate.

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di Tomaso E, Beltramo M, and Piomelli D

Nature 382(6593):677-8, 1996 Aug 22 - Who cited this? | PubMed ID: 8751435 | Fulltext

Carbohydrate-deficient glycoprotein syndrome: normal glycosylation in the fetus.

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Clayton P, Winchester B, Di Tomaso E, Young E, Keir G, and Rodeck C

Lancet 341(8850):956, 1993 Apr 10 - Who cited this? | PubMed ID: 8096285 | Fulltext

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