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Papers authored by Dekeyne A

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Discriminative stimulus properties of the "atypical" antidepressant, mirtazapine, in rats: a pharmacological characterization.

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Dekeyne A and Millan MJ

Psychopharmacology 203(2):329-41, 2009 Apr - Who cited this? | PubMed ID: 18709360 | Fulltext

The melanin-concentrating hormone1 receptor antagonists, SNAP-7941 and GW3430, enhance social recognition and dialysate levels of acetylcholine in the frontal cortex of rats.

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Millan MJ, Gobert A, Panayi F, Rivet JM, Dekeyne A, Brocco M, Ortuno JC, and Di Cara B

The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 11(8):1105-22, 2008 Dec - Who cited this? | PubMed ID: 18466669 | Fulltext

Neurokinin(1) Antagonists Potentiate Antidepressant Properties of Serotonin Reuptake Inhibitors, Yet Blunt Their Anxiogenic Actions: A Neurochemical, Electrophysiological, and Behavioral Characterization.

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Gobert A, Brocco M, Dekeyne A, Di Cara B, Bouchez G, Lejeune F, Gannon RL, and Millan MJ

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008 Oct 1 - Who cited this? | PubMed ID: 18830239 | Fulltext

Cellular and behavioural profile of the novel, selective neurokinin(1) receptor antagonist, vestipitant: A comparison to other agents.

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Brocco M, Dekeyne A, Mannoury la Cour C, Touzard M, Girardon S, Veiga S, de Nanteuil G, Dejong TR, Olivier B, and Millan MJ

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 18(10):729-50, 2008 Oct - Who cited this? | PubMed ID: 18657401 | Fulltext

S32006, a novel 5-HT(2C) receptor antagonist displaying broad-based antidepressant and anxiolytic properties in rodent models.

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Dekeyne A, Mannoury la Cour C, Gobert A, Brocco M, Lejeune F, Serres F, Sharp T, Daszuta A, Soumier A, Papp M, Rivet JM, Flik G, Cremers TI, Muller O, Lavielle G, and Millan MJ

Psychopharmacology 199(4):549-68, 2008 Sep - Who cited this? | PubMed ID: 18523738 | Fulltext

S33138 (N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1] benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenyl-acetamide), a Preferential Dopamine D3 versus D2 Receptor Antagonist and Potential Antipsychotic Agent: III. Actions in Models of Therapeutic Activity and Induction of Side Effects.

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Millan MJ, Loiseau F, Dekeyne A, Gobert A, Flik G, Cremers TI, Rivet JM, Sicard D, Billiras R, and Brocco M

The Journal of pharmacology and experimental therapeutics 324(3):1212-26, 2008 Mar - Who cited this? | PubMed ID: 18096759 | Fulltext

S33138 [N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1]-benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenylacetamide], a preferential dopamine D3 versus D2 receptor antagonist and potential antipsychotic agent. II. A neurochemical, electrophysiological and behavioral characterization in vivo.

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Millan MJ, Svenningsson P, Ashby CR, Hill M, Egeland M, Dekeyne A, Brocco M, Di Cara B, Lejeune F, Thomasson N, Munoz C, Mocaër E, Crossman A, Cistarelli L, Girardon S, Iob L,

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The Journal of pharmacology and experimental therapeutics 324(2):600-11, 2008 Feb - Who cited this? | PubMed ID: 18024787 | Fulltext

Pro-cognitive effects of 5-HT(6) receptor antagonists in the social recognition procedure in rats: implication of the frontal cortex.

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Loiseau F, Dekeyne A, and Millan MJ

Psychopharmacology 196(1):93-104, 2008 Jan - Who cited this? | PubMed ID: 17922111 | Fulltext

Discriminative stimulus properties of the selective norepinephrine reuptake inhibitor, reboxetine, in rats: a characterization with alpha/beta-adrenoceptor subtype selective ligands, antidepressants, and antagonists at neuropeptide receptors.

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Millan MJ and Dekeyne A

The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 10(5):579-93, 2007 Oct - Who cited this? | PubMed ID: 17076935 | Fulltext

Activation of dopamine D1 receptors enhances cholinergic transmission and social cognition: a parallel dialysis and behavioural study in rats.

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Di Cara B, Panayi F, Gobert A, Dekeyne A, Sicard D, De Groote L, and Millan MJ

The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 10(3):383-99, 2007 Jun - Who cited this? | PubMed ID: 16925890 | Fulltext

Discriminative stimulus properties of S32504, a novel D3/D2 receptor agonist and antiparkinson agent, in rats: attenuation by the antipsychotics, aripiprazole, bifeprunox, N-desmethylclozapine, and by selective antagonists at dopamine D2 but not D3 recept.

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Millan MJ, Iob L, Péglion JL, and Dekeyne A

Psychopharmacology 191(3):767, 2007 Apr - Who cited this? | PubMed ID: 17047933 | Fulltext

Selective blockade of dopamine D(3) versus D(2) receptors enhances frontocortical cholinergic transmission and social memory in rats: a parallel neurochemical and behavioural analysis.

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Millan MJ, Di Cara B, Dekeyne A, Panayi F, De Groote L, Sicard D, Cistarelli L, Billiras R, and Gobert A

Journal of neurochemistry 100(4):1047-61, 2007 Feb - Who cited this? | PubMed ID: 17266737 | Fulltext

Antidepressant-like properties of the anti-Parkinson agent, piribedil, in rodents: mediation by dopamine D2 receptors.

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Brocco M, Dekeyne A, Papp M, and Millan MJ

Behavioural pharmacology 17(7):559-72, 2006 Nov - Who cited this? | PubMed ID: 17021388 | Fulltext

Discriminative stimulus properties of the selective and highly potent alpha2-adrenoceptor agonist, S18616, in rats: mediation by the alpha2A subtype, and blockade by the atypical antidepressants, mirtazapine and mianserin.

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Dekeyne A and Millan MJ

Neuropharmacology 51(4):718-26, 2006 Sep - Who cited this? | PubMed ID: 16814817 | Fulltext

Anxiolytic properties of agomelatine, an antidepressant with melatoninergic and serotonergic properties: role of 5-HT2C receptor blockade.

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Millan MJ, Brocco M, Gobert A, and Dekeyne A

Psychopharmacology 177(4):448-58, 2005 Feb - Who cited this? | PubMed ID: 15289999 | Fulltext

Behavioural models for the characterisation of established and innovative antidepressant agents.

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Dekeyne A

Therapie 60(5):477-84, 2005 - Who cited this? | PubMed ID: 16433013 | Fulltext

The serotonin1A receptor partial agonist S15535 [4-(benzodioxan-5-yl)1-(indan-2-yl)piperazine] enhances cholinergic transmission and cognitive function in rodents: a combined neurochemical and behavioral analysis.

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Millan MJ, Gobert A, Roux S, Porsolt R, Meneses A, Carli M, Di Cara B, Jaffard R, Rivet JM, Lestage P, Mocaer E, Peglion JL, and Dekeyne A

The Journal of pharmacology and experimental therapeutics 311(1):190, 2004 Oct - Who cited this? | PubMed ID: 15146031 | Fulltext

S32504, a novel naphtoxazine agonist at dopamine D3/D2 receptors: III. Actions in models of potential antidepressive and anxiolytic activity in comparison with ropinirole.

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Millan MJ, Brocco M, Papp M, Serres F, La Rochelle CD, Sharp T, Peglion JL, and Dekeyne A

The Journal of pharmacology and experimental therapeutics 309(3):936-50, 2004 Jun - Who cited this? | PubMed ID: 14978196 | Fulltext

The novel melatonin agonist agomelatine (S20098) is an antagonist at 5-hydroxytryptamine2C receptors, blockade of which enhances the activity of frontocortical dopaminergic and adrenergic pathways.

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Millan MJ, Gobert A, Lejeune F, Dekeyne A, Newman-Tancredi A, Pasteau V, Rivet JM, and Cussac D

The Journal of pharmacology and experimental therapeutics 306(3):954-64, 2003 Sep - Who cited this? | PubMed ID: 12750432 | Fulltext

Discriminative stimulus properties of antidepressant agents: a review.

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Dekeyne A and Millan MJ

Behavioural pharmacology 14(5-6):391-407, 2003 Sep - Who cited this? | PubMed ID: 14501253 | Fulltext

Generalization of clozapine as compared to other antipsychotic agents to a discriminative stimulus elicited by the serotonin (5-HT)2A antagonist, MDL100,907.

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Dekeyne A, Iob L, and Millan MJ

Neuropharmacology 44(5):604-15, 2003 Apr - Who cited this? | PubMed ID: 12668046 | Fulltext

Differential modulation of efficiency in a food-rewarded "differential reinforcement of low-rate" 72-s schedule in rats by norepinephrine and serotonin reuptake inhibitors.

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Dekeyne A, Gobert A, Auclair A, Girardon S, and Millan MJ

Psychopharmacology 162(2):156-67, 2002 Jul - Who cited this? | PubMed ID: 12110993 | Fulltext

Induction of hyperlocomotion in mice exposed to a novel environment by inhibition of serotonin reuptake. A pharmacological characterization of diverse classes of antidepressant agents.

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Brocco M, Dekeyne A, Veiga S, Girardon S, and Millan MJ

Pharmacology, biochemistry, and behavior 71(4):667-80, 2002 Apr - Who cited this? | PubMed ID: 11888558 | Fulltext

The selective serotonin(2A) receptor antagonist, MDL100,907, elicits a specific interoceptive cue in rats.

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Dekeyne A, Iob L, Hautefaye P, and Millan MJ

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 26(4):552-6, 2002 Apr - Who cited this? | PubMed ID: 11927180 | Fulltext

Stereospecific blockade of marble-burying behaviour in mice by selective, non-peptidergic neurokinin1 (NK1) receptor antagonists.

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Millan MJ, Girardon S, Mullot J, Brocco M, and Dekeyne A

Neuropharmacology 42(5):677-84, 2002 Apr - Who cited this? | PubMed ID: 11985826 | Fulltext

Improvement in the selectivity and metabolic stability of the serotonin 5-HT(1A) ligand, S 15535: a series of cis- and trans-2-(arylcycloalkylamine) 1-indanols.

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Peglion JL, Goument B, Despaux N, Charlot V, Giraud H, Nisole C, Newman-Tancredi A, Dekeyne A, Bertrand M, Genissel P, and Millan MJ

Journal of medicinal chemistry 45(1):165-76, 2002 Jan 3 - Who cited this? | PubMed ID: 11754589 | Fulltext

Discriminative stimulus properties of the selective norepinephrine reuptake inhibitor, reboxetine, in rats.

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Dekeyne A, Gobert A, Iob L, Cistarelli L, Melon C, and Millan MJ

Psychopharmacology 158(2):213-8, 2001 Nov - Who cited this? | PubMed ID: 11702096 | Fulltext

Anxiolytic properties of the selective, non-peptidergic CRF(1) antagonists, CP154,526 and DMP695: a comparison to other classes of anxiolytic agent.

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Millan MJ, Brocco M, Gobert A, Dorey G, Casara P, and Dekeyne A

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 25(4):585-600, 2001 Oct - Who cited this? | PubMed ID: 11557172 | Fulltext

S33005, a novel ligand at both serotonin and norepinephrine transporters: II. Behavioral profile in comparison with venlafaxine, reboxetine, citalopram, and clomipramine.

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Millan MJ, Dekeyne A, Papp M, La Rochelle CD, MacSweeny C, Peglion JL, and Brocco M

The Journal of pharmacology and experimental therapeutics 298(2):581-91, 2001 Aug - Who cited this? | PubMed ID: 11454919 | Fulltext

Generalization of serotonin (5-HT)1A agonists and the antipsychotics, clozapine, ziprasidone and S16924, but not haloperidol, to the discriminative stimuli elicited by PD128,907 and 7-OH-DPAT.

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Dekeyne A, Rivet JM, Gobert A, and Millan MJ

Neuropharmacology 40(7):899-910, 2001 Jun - Who cited this? | PubMed ID: 11378160 | Fulltext

Following long-term training with citalopram, both mirtazapine and mianserin block its discriminative stimulus properties in rats.

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Dekeyne A, Iob L, and Millan MJ

Psychopharmacology 153(3):389-92, 2001 Jan - Who cited this? | PubMed ID: 11271412 | Fulltext

S18616, a highly potent, spiroimidazoline agonist at alpha(2)-adrenoceptors: I. Receptor profile, antinociceptive and hypothermic actions in comparison with dexmedetomidine and clonidine.

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Millan MJ, Dekeyne A, Newman-Tancredi A, Cussac D, Audinot V, Milligan G, Duqueyroix D, Girardon S, Mullot J, Boutin JA, Nicolas JP, Renouard-Try A, Lacoste JM, and Cordi A

The Journal of pharmacology and experimental therapeutics 295(3):1192-205, 2000 Dec - Who cited this? | PubMed ID: 11082457 | Fulltext

S18616, a highly potent spiroimidazoline agonist at alpha(2)-adrenoceptors: II. Influence on monoaminergic transmission, motor function, and anxiety in comparison with dexmedetomidine and clonidine.

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Millan MJ, Lejeune F, Gobert A, Brocco M, Auclair A, Bosc C, Rivet JM, Lacoste JM, Cordi A, and Dekeyne A

The Journal of pharmacology and experimental therapeutics 295(3):1206-22, 2000 Dec - Who cited this? | PubMed ID: 11082458 | Fulltext

The selective serotonin (5-HT)1A receptor ligand, S15535, displays anxiolytic-like effects in the social interaction and Vogel models and suppresses dialysate levels of 5-HT in the dorsal hippocampus of freely-moving rats. A comparison with other anxiolytic agents.

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Dekeyne A, Brocco M, Adhumeau A, Gobert A, and Millan MJ

Psychopharmacology 152(1):55-66, 2000 Sep - Who cited this? | PubMed ID: 11041316 | Fulltext

The ability of WAY100,635 to potentiate the neurochemical and functional actions of fluoxetine is enhanced by co-administration of SB224,289, but not BRL15572.

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Gobert A, Dekeyne A, and Millan MJ

Neuropharmacology 39(9):1608-16, 2000 Jul 10 - Who cited this? | PubMed ID: 10854905 | Fulltext

S33084, a novel, potent, selective, and competitive antagonist at dopamine D(3)-receptors: II. Functional and behavioral profile compared with GR218,231 and L741,626.

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Millan MJ, Dekeyne A, Rivet JM, Dubuffet T, Lavielle G, and Brocco M

The Journal of pharmacology and experimental therapeutics 293(3):1063-73, 2000 Jun - Who cited this? | PubMed ID: 10869411 | Fulltext

Citalopram reduces social interaction in rats by activation of serotonin (5-HT)(2C) receptors.

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Dekeyne A, Denorme B, Monneyron S, and Millan MJ

Neuropharmacology 39(6):1114-7, 2000 Apr 3 - Who cited this? | PubMed ID: 10727723 | Fulltext

Mirtazapine enhances frontocortical dopaminergic and corticolimbic adrenergic, but not serotonergic, transmission by blockade of alpha2-adrenergic and serotonin2C receptors: a comparison with citalopram.

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Millan MJ, Gobert A, Rivet JM, Adhumeau-Auclair A, Cussac D, Newman-Tancredi A, Dekeyne A, Nicolas JP, and Lejeune F

The European journal of neuroscience 12(3):1079-95, 2000 Mar - Who cited this? | PubMed ID: 10762339 | Fulltext

Discriminative stimulus properties of the dopamine D3 receptor agonists, PD128,907 and 7-OH-DPAT: a comparative characterization with novel ligands at D3 versus D2 receptors.

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Millan MJ, Girardon S, Monneyron S, and Dekeyne A

Neuropharmacology 39(4):586-98, 2000 Feb 14 - Who cited this? | PubMed ID: 10728880 | Fulltext

Agonist and antagonist actions of yohimbine as compared to fluparoxan at alpha(2)-adrenergic receptors (AR)s, serotonin (5-HT)(1A), 5-HT(1B), 5-HT(1D) and dopamine D(2) and D(3) receptors. Significance for the modulation of frontocortical monoaminergic transmission and depressive states.

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Millan MJ, Newman-Tancredi A, Audinot V, Cussac D, Lejeune F, Nicolas JP, Cogé F, Galizzi JP, Boutin JA, Rivet JM, Dekeyne A, and Gobert A

Synapse (New York, N.Y.) 35(2):79-95, 2000 Feb - Who cited this? | PubMed ID: 10611634 | Fulltext

S18327 (1-[2-[4-(6-fluoro-1, 2-benzisoxazol-3-yl)piperid-1-yl]ethyl]3-phenyl imidazolin-2-one), a novel, potential antipsychotic displaying marked antagonist properties at alpha(1)- and alpha(2)-adrenergic receptors: II. Functional profile and a multiparametric comparison with haloperidol, clozapine, and 11 other antipsychotic agents.

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Millan MJ, Brocco M, Rivet JM, Audinot V, Newman-Tancredi A, Maiofiss L, Queriaux S, Despaux N, Peglion JL, and Dekeyne A

The Journal of pharmacology and experimental therapeutics 292(1):54-66, 2000 Jan - Who cited this? | PubMed ID: 10604931 | Fulltext

Inverse agonists and serotonergic transmission: from recombinant, human serotonin (5-HT)1B receptors to G-protein coupling and function in corticolimbic structures in vivo.

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Millan MJ, Gobert A, Audinot V, Dekeyne A, and Newman-Tancredi A

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 21(2 Suppl):61S-67S, 1999 Aug - Who cited this? | PubMed ID: 10432490 | Fulltext

S-16924, a novel, potential antipsychotic with marked serotonin1A agonist properties. IV. A drug discrimination comparison with clozapine.

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Millan MJ, Schreiber R, Monneyron S, Denorme B, Melon C, Queriaux S, and Dekeyne A

The Journal of pharmacology and experimental therapeutics 289(1):427, 1999 Apr - Who cited this? | PubMed ID: 10087034 | Fulltext

5-HT2C receptors are involved in the discriminative stimulus effects of citalopram in rats.

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Millan MJ, Girardon S, and Dekeyne A

Psychopharmacology 142(4):432, 1999 Mar - Who cited this? | PubMed ID: 10229070 | Fulltext

S-16924 [(R)-2-[1-[2-(2,3-dihydro-benzo[1,4]dioxin-5-yloxy)-ethyl]- pyrrolidin-3yl]-1-(4-fluorophenyl)-ethanone], a novel, potential antipsychotic with marked serotonin1A agonist properties: III. Anxiolytic actions in comparison with clozapine and haloperidol.

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Millan MJ, Brocco M, Gobert A, Schreiber R, and Dekeyne A

The Journal of pharmacology and experimental therapeutics 288(3):1002-14, 1999 Mar - Who cited this? | PubMed ID: 10027837 | Fulltext

Discriminative stimulus properties of the novel serotonin (5-HT)2C receptor agonist, RO 60-0175: a pharmacological analysis.

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Dekeyne A, Girardon S, and Millan MJ

Neuropharmacology 38(3):415-23, 1999 Mar - Who cited this? | PubMed ID: 10219979 | Fulltext

Citalopram elicits a discriminative stimulus in rats at a dose selectively increasing extracellular levels of serotonin vs. dopamine and noradrenaline.

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Millan MJ, Gobert A, Girardon S, and Dekeyne A

European journal of pharmacology 364(2-3):147-50, 1999 Jan 8 - Who cited this? | PubMed ID: 9932717 | Fulltext

S 18126 ([2-[4-(2,3-dihydrobenzo[1,4]dioxin-6-yl)piperazin-1-yl methyl]indan-2-yl]), a potent, selective and competitive antagonist at dopamine D4 receptors: an in vitro and in vivo comparison with L 745,870 (3-(4-[4-chlorophenyl]piperazin-1-yl)methyl-1H-pyrrolo[2, 3b]pyridine) and raclopride.

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Millan MJ, Newman-Tancredi A, Brocco M, Gobert A, Lejeune F, Audinot V, Rivet JM, Schreiber R, Dekeyne A, Spedding M, Nicolas JP, and Peglion JL

The Journal of pharmacology and experimental therapeutics 287(1):167-86, 1998 Oct - Who cited this? | PubMed ID: 9765336 | Fulltext

A comparative in vitro and in vivo pharmacological characterization of the novel dopamine D3 receptor antagonists (+)-S 14297, nafadotride, GR 103,691 and U 99194.

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Audinot V, Newman-Tancredi A, Gobert A, Rivet JM, Brocco M, Lejeune F, Gluck L, Desposte I, Bervoets K, Dekeyne A, and Millan MJ

The Journal of pharmacology and experimental therapeutics 287(1):187-97, 1998 Oct - Who cited this? | PubMed ID: 9765337 | Fulltext

Pharmacological stimuli decreasing nucleus accumbens dopamine can act as positive reinforcers but have a low addictive potential.

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Marinelli M, Barrot M, Simon H, Oberlander C, Dekeyne A, Le Moal M, and Piazza PV

The European journal of neuroscience 10(10):3269-75, 1998 Oct - Who cited this? | PubMed ID: 9786220 | Fulltext

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