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Papers authored by Danishefsky SJ

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Diverted Total Synthesis Leads to the Generation of Promising Cell-Migration Inhibitors for Treatment of Tumor Metastasis: In vivo and Mechanistic Studies on the Migrastatin Core Ether Analog.

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Oskarsson T, Nagorny P, Krauss IJ, Perez L, Mandal M, Yang G, Ouerfelli O, Xiao D, Moore MA, Massagué J, and Danishefsky SJ

Journal of the American Chemical Society 132(9):3224-8, 2010 Mar 10 - Who cited this? | PubMed ID: 20155906 | Fulltext

Total synthesis of the 2,6-sialylated immunoglobulin G glycopeptide fragment in homogeneous form.

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Wang P, Zhu J, Yuan Y, and Danishefsky SJ

Journal of the American Chemical Society 131(46):16669-71, 2009 Nov 25 - Who cited this? | PubMed ID: 19886622 | Fulltext

A practical total synthesis of globo-h for use in anticancer vaccines.

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Jeon I, Iyer K, and Danishefsky SJ

The Journal of organic chemistry 74(21):8452-5, 2009 Nov 6 - Who cited this? | PubMed ID: 19874068 | Fulltext

A New Model for the Presentation of Tumor-Associated Antigens and the Quest for an Anticancer Vaccine: A Solution to the Synthesis Challenge via Ring-Closing Metathesis.

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Jeon I, Lee D, Krauss IJ, and Danishefsky SJ

Journal of the American Chemical Society 131(40):14337-44, 2009 Oct 14 - Who cited this? | PubMed ID: 19746915 | Fulltext

Synthetic carbohydrate-based anticancer vaccines: the Memorial Sloan-Kettering experience.

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Zhu J, Warren JD, and Danishefsky SJ

Expert review of vaccines 8(10):1399-413, 2009 Oct - Who cited this? | PubMed ID: 19803761 | Fulltext

Thio FCMA Intermediates as Strong Acyl Donors: A General Solution to the Formation of Complex Amide Bonds.

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Rao Y, Li X, and Danishefsky SJ

Journal of the American Chemical Society 131(36):12924-6, 2009 Sep 16 - Who cited this? | PubMed ID: 19697932 | Fulltext

Improved dienophilicity of nitrocycloalkenes: prospects for the development of a trans-Diels-Alder paradigm.

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Kim WH, Lee JH, and Danishefsky SJ

Journal of the American Chemical Society 131(35):12576-8, 2009 Sep 9 - Who cited this? | PubMed ID: 19685875 | Fulltext

Origins of the regioselectivities in the Diels-Alder reactions of vinylindenes with 1,4-quinone monoketal and acrolein dienophiles.

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Hayden AE, DeChancie J, George AH, Dai M, Yu M, Danishefsky SJ, and Houk KN

The Journal of organic chemistry 74(17):6770-6, 2009 Sep 4 - Who cited this? | PubMed ID: 19663431 | Fulltext

Total synthesis and structural revision of (+/-)-tricholomalides a and B.

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Wang Z, Min SJ, and Danishefsky SJ

Journal of the American Chemical Society 131(31):10848-9, 2009 Aug 12 - Who cited this? | PubMed ID: 19722666 | Fulltext

On the Emerging Role of Chemistry in the Fashioning of Biologics: Synthesis of a Bidomainal Fucosyl GM1-Based Vaccine for the Treatment of Small Cell Lung Cancer.

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Nagorny P, Kim WH, Wan Q, Lee D, and Danishefsky SJ

The Journal of organic chemistry 74(15):5157-62, 2009 Aug 7 - Who cited this? | PubMed ID: 19555091 | Fulltext

From synthesis to biologics: preclinical data on a chemistry derived anticancer vaccine.

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Zhu J, Wan Q, Lee D, Yang G, Spassova MK, Ouerfelli O, Ragupathi G, Damani P, Livingston PO, and Danishefsky SJ

Journal of the American Chemical Society 131(26):9298-303, 2009 Jul 8 - Who cited this? | PubMed ID: 19518111 | Fulltext

Toward fully synthetic homogeneous beta-human follicle-stimulating hormone (beta-hFSH) with a biantennary N-linked dodecasaccharide. synthesis of beta-hFSH with chitobiose units at the natural linkage sites.

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Nagorny P, Fasching B, Li X, Chen G, Aussedat B, and Danishefsky SJ

Journal of the American Chemical Society 131(16):5792-9, 2009 Apr 29 - Who cited this? | PubMed ID: 19341309 | Fulltext

Toward homogeneous erythropoietin: chemical synthesis of the ala(1)-gly(28) glycopeptide domain by "alanine" ligation.

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Kan C, Trzupek JD, Wu B, Wan Q, Chen G, Tan Z, Yuan Y, and Danishefsky SJ

Journal of the American Chemical Society 131(15):5438-43, 2009 Apr 22 - Who cited this? | PubMed ID: 19334679 | Fulltext

Toward Homogeneous Erythropoietin: Non-NCL-Based Chemical Synthesis of the Gln(78)-Arg(166) Glycopeptide Domain.

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Tan Z, Shang S, Halkina T, Yuan Y, and Danishefsky SJ

Journal of the American Chemical Society 131(15):5424-31, 2009 Apr 22 - Who cited this? | PubMed ID: 19334683 | Fulltext

Biologics through chemistry: total synthesis of a proposed dual-acting vaccine targeting ovarian cancer by orchestration of oligosaccharide and polypeptide domains.

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Zhu J, Wan Q, Ragupathi G, George CM, Livingston PO, and Danishefsky SJ

Journal of the American Chemical Society 131(11):4151-8, 2009 Mar 25 - Who cited this? | PubMed ID: 19253940 | Fulltext

Total synthesis of spirotenuipesines a and B.

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Dai M, Krauss IJ, and Danishefsky SJ

The Journal of organic chemistry 73(24):9576-83, 2008 Dec 19 - Who cited this? | PubMed ID: 18973385 | Fulltext

Synthesis of pluraflavin A "aglycone".

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Wright BJ, Hartung J, Peng F, Van de Water R, Liu H, Tan QH, Chou TC, and Danishefsky SJ

Journal of the American Chemical Society 130(49):16786-90, 2008 Dec 10 - Who cited this? | PubMed ID: 19049469 | Fulltext

Oxo-ester mediated native chemical ligation: concept and applications.

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Wan Q, Chen J, Yuan Y, and Danishefsky SJ

Journal of the American Chemical Society 130(47):15814-6, 2008 Nov 26 - Who cited this? | PubMed ID: 18855357 | Fulltext

On the two-component microwave-mediated reaction of isonitriles with carboxylic acids: regarding alleged formimidate carboxylate mixed anhydrides.

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Li X, Yuan Y, Berkowitz WF, Todaro LJ, and Danishefsky SJ

Journal of the American Chemical Society 130(40):13222-4, 2008 Oct 8 - Who cited this? | PubMed ID: 18783224 | Fulltext

An oligosaccharide-based HIV-1 2G12 mimotope vaccine induces carbohydrate-specific antibodies that fail to neutralize HIV-1 virions.

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Joyce JG, Krauss IJ, Song HC, Opalka DW, Grimm KM, Nahas DD, Esser MT, Hrin R, Feng M, Dudkin VY, Chastain M, Shiver JW, and Danishefsky SJ

Proceedings of the National Academy of Sciences of the United States of America, 2008 Oct 6 - Who cited this? | PubMed ID: 18838688 | Fulltext

Native Chemical Ligation at Valine: A Contribution to Peptide and Glycopeptide Synthesis.

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Chen J, Wan Q, Yuan Y, Zhu J, and Danishefsky SJ

Angewandte Chemie (International ed. in English), 2008 Oct 2 - Who cited this? | PubMed ID: 18833563 | Fulltext

Toward a Prostate Specific Antigen-Based Prostate Cancer Diagnostic Assay: Preparation of Keyhole Limpet Hemocyanin -Conjugated Normal and Transformed Prostate Specific Antigen Fragments.

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Dudkin VY, Miller JS, Dudkina AS, Antczak C, Scheinberg DA, and Danishefsky SJ

Journal of the American Chemical Society, 2008 Sep 18 - Who cited this? | PubMed ID: 18798614 | Fulltext

The coupling of isonitriles and carboxylic acids occurring by sequential concerted rearrangement mechanisms.

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Jones GO, Li X, Hayden AE, Houk KN, and Danishefsky SJ

Organic letters 10(18):4093-6, 2008 Sep 18 - Who cited this? | PubMed ID: 18707109 | Fulltext

Total Syntheses of (+)- and (-)-Peribysin E.

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Angeles AR, Waters SP, and Danishefsky SJ

Journal of the American Chemical Society, 2008 Sep 11 - Who cited this? | PubMed ID: 18783227 | Fulltext

Addressing Mechanistic Issues in the Coupling of Isonitriles and Carboxylic Acids: Potential Routes to Peptidic Constructs.

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Li X, Yuan Y, Kan C, and Danishefsky SJ

Journal of the American Chemical Society, 2008 Sep 11 - Who cited this? | PubMed ID: 18783225 | Fulltext

Therapeutic effect against human xenograft tumors in nude mice by the third generation microtubule stabilizing epothilones.

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Chou TC, Zhang X, Zhong ZY, Li Y, Feng L, Eng S, Myles DR, Johnson R, Wu N, Yin YI, Wilson RM, and Danishefsky SJ

Proceedings of the National Academy of Sciences of the United States of America, 2008 Aug 28 - Who cited this? | PubMed ID: 18755900 | Fulltext

New chemistry with old functional groups: on the reaction of isonitriles with carboxylic acids-a route to various amide types.

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Li X and Danishefsky SJ

Journal of the American Chemical Society 130(16):5446-8, 2008 Apr 23 - Who cited this? | PubMed ID: 18370392 | Fulltext

A direct route to fluostatin C by a fascinating Diels-Alder reaction.

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Yu M and Danishefsky SJ

Journal of the American Chemical Society 130(9):2783-5, 2008 Mar 5 - Who cited this? | PubMed ID: 18254631 | Fulltext

Synthesis and cytotoxic evaluation of some cribrostatin-ecteinascidin analogues.

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Wright BJ, Chan C, and Danishefsky SJ

Journal of natural products 71(3):409-14, 2008 Mar - Who cited this? | PubMed ID: 18278868 | Fulltext

Noncatalytic reaction of isonitriles and carboxylic acids en route to amide-type linkages.

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Li X and Danishefsky SJ

Nature protocols 3(10):1666-70, 2008 - Who cited this? | PubMed ID: 18833204 | Fulltext

Fully synthetic carbohydrate HIV antigens designed on the logic of the 2G12 antibody.

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Krauss IJ, Joyce JG, Finnefrock AC, Song HC, Dudkin VY, Geng X, Warren JD, Chastain M, Shiver JW, and Danishefsky SJ

Journal of the American Chemical Society 129(36):11042-4, 2007 Sep 12 - Who cited this? | PubMed ID: 17711286 | Fulltext

Total synthesis of (+)-suaveolindole: establishment of its absolute configuration.

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Velthuisen EJ and Danishefsky SJ

Journal of the American Chemical Society 129(35):10640-1, 2007 Sep 5 - Who cited this? | PubMed ID: 17696355 | Fulltext

Creating quaternary centers with high exo stereoselectivity using activated alpha-alkynyl dienophiles.

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Min SJ, Jones GO, Houk KN, and Danishefsky SJ

Journal of the American Chemical Society 129(33):10078-9, 2007 Aug 22 - Who cited this? | PubMed ID: 17655309 | Fulltext

Applications of total synthesis toward the discovery of clinically useful anticancer agents.

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Wilson RM and Danishefsky SJ

Chemical Society reviews 36(8):1207-26, 2007 Aug - Who cited this? | PubMed ID: 17619682 | Fulltext

Pattern recognition in retrosynthetic analysis: snapshots in total synthesis.

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Wilson RM and Danishefsky SJ

The Journal of organic chemistry 72(12):4293-305, 2007 Jun 8 - Who cited this? | PubMed ID: 17539594 | Fulltext

The total synthesis of spirotenuipesines A and B.

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Dai M and Danishefsky SJ

Journal of the American Chemical Society 129(12):3498-9, 2007 Mar 28 - Who cited this? | PubMed ID: 17335213 | Fulltext

Chemistry and biology in search of antimetastatic agents.

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Pérez L and Danishefsky SJ

ACS chemical biology 2(3):159-62, 2007 Mar 20 - Who cited this? | PubMed ID: 17373763 | Fulltext

Highly selective Diels-Alder reactions of directly connected enyne dienophiles.

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Dai M, Sarlah D, Yu M, Danishefsky SJ, Jones GO, and Houk KN

Journal of the American Chemical Society 129(3):645-57, 2007 Jan 24 - Who cited this? | PubMed ID: 17227028 | Fulltext

Total synthesis of paecilomycine A.

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Min SJ and Danishefsky SJ

Angewandte Chemie (International ed. in English) 46(13):2199, 2007 - Who cited this? | PubMed ID: 17300126 | Fulltext

On the rearrangement of an azaspiroindolenine to a precursor to phalarine: mechanistic insights.

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Li C, Chan C, Heimann AC, and Danishefsky SJ

Angewandte Chemie (International ed. in English) 46(9):1444-7, 2007 - Who cited this? | PubMed ID: 17387654 | Fulltext

Total synthesis of phalarine.

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Li C, Chan C, Heimann AC, and Danishefsky SJ

Angewandte Chemie (International ed. in English) 46(9):1448-50, 2007 - Who cited this? | PubMed ID: 17387655 | Fulltext

Total synthesis of peribysin E necessitates revision of the assignment of its absolute configuration.

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Angeles AR, Dorn DC, Kou CA, Moore MA, and Danishefsky SJ

Angewandte Chemie (International ed. in English) 46(9):1451-4, 2007 - Who cited this? | PubMed ID: 17387656 | Fulltext

Total synthesis of (+)-isomigrastatin.

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Krauss IJ, Mandal M, and Danishefsky SJ

Angewandte Chemie (International ed. in English) 46(29):5576-9, 2007 - Who cited this? | PubMed ID: 17583888 | Fulltext

Development of efficient methods for accomplishing cysteine-free peptide and glycopeptide coupling.

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Chen G, Wan Q, Tan Z, Kan C, Hua Z, Ranganathan K, and Danishefsky SJ

Angewandte Chemie (International ed. in English) 46(39):7383-7, 2007 - Who cited this? | PubMed ID: 17828726 | Fulltext

Conformational locking through allylic strain as a device for stereocontrol--total synthesis of grandisine A.

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Maloney DJ and Danishefsky SJ

Angewandte Chemie (International ed. in English) 46(41):7789-92, 2007 - Who cited this? | PubMed ID: 17876796 | Fulltext

Differentiation of nonconventional "carbanions"-the total synthesis of nemorosone and clusianone.

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Tsukano C, Siegel DR, and Danishefsky SJ

Angewandte Chemie (International ed. in English) 46(46):8840-4, 2007 - Who cited this? | PubMed ID: 17935090 | Fulltext

Free-radical-based, specific desulfurization of cysteine: a powerful advance in the synthesis of polypeptides and glycopolypeptides.

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Wan Q and Danishefsky SJ

Angewandte Chemie (International ed. in English) 46(48):9248-52, 2007 - Who cited this? | PubMed ID: 18046687 | Fulltext

The total synthesis of (+/-)-11-O-debenzoyltashironin.

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Cook SP, Polara A, and Danishefsky SJ

Journal of the American Chemical Society 128(51):16440-1, 2006 Dec 27 - Who cited this? | PubMed ID: 17177359 | Fulltext

An interesting issue of Diels-Alder selectivity discovered en route to 11-O-debenzoyltashironin.

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Cook SP and Danishefsky SJ

Organic letters 8(25):5693-5, 2006 Dec 7 - Who cited this? | PubMed ID: 17134249 | Fulltext

A total synthesis of xestodecalactone a and proof of its absolute stereochemistry: interesting observations on dienophilic control with 1,3-disubstituted nonequivalent allenes.

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Yoshino T, Ng F, and Danishefsky SJ

Journal of the American Chemical Society 128(43):14185-91, 2006 Nov 1 - Who cited this? | PubMed ID: 17061903 | Fulltext

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