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Papers authored by Cross NC

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Harmonization of molecular monitoring of CML therapy in Europe.

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Müller MC, Cross NC, Erben P, Schenk T, Hanfstein B, Ernst T, Hehlmann R, Branford S, Saglio G, and Hochhaus A

Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 23(11):1957-63, 2009 Nov - Who cited this? | PubMed ID: 19710700 | Fulltext

A high-throughput candidate gene mutation screen in lymphoproliferative and myeloproliferative neoplasias.

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Kreil S, Hochhaus A, Cross NC, and Chase A

Leukemia research 33(9):e168-9, 2009 Sep - Who cited this? | PubMed ID: 19464057 | Fulltext

Clinical evidence for a graft-versus-tumour effect following allogeneic HSCT for t(8;13) atypical myeloproliferative disorder.

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Townsend W, Cross NC, Waghorn K, Somana K, Ramsay A, Thomson K, and Peggs K

Bone marrow transplantation 44(3):197-9, 2009 Aug - Who cited this? | PubMed ID: 19234514 | Fulltext

Frequent upregulation of MYC in plasma cell leukemia.

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Chiecchio L, Dagrada GP, White HE, Towsend MR, Protheroe RK, Cheung KL, Stockley DM, Orchard KH, Cross NC, Harrison CJ, Ross FM, and UK Myeloma Forum

Genes, chromosomes & cancer 48(7):624-36, 2009 Jul - Who cited this? | PubMed ID: 19396865 | Fulltext

Loss of 1p and rearrangement of MYC are associated with progression of smouldering myeloma to myeloma: sequential analysis of a single case.

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Chiecchio L, Dagrada GP, Protheroe RK, Stockley DM, Smith AG, Orchard KH, Cross NC, Harrison CJ, Ross FM, and UK Myeloma Forum

Haematologica 94(7):1024-8, 2009 Jul - Who cited this? | PubMed ID: 19454499 | Fulltext

Acute myeloid leukaemia with associated eosinophilia: justification for FIP1L1-PDGFRA screening in cases lacking the CBFB-MYH11 fusion gene.

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Sorour Y, Dalley CD, Snowden JA, Cross NC, and Reilly JT

British journal of haematology 146(2):225-7, 2009 Jul - Who cited this? | PubMed ID: 19466970 | Fulltext

Frequent CBL mutations associated with 11q acquired uniparental disomy in myeloproliferative neoplasms.

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Grand FH, Hidalgo-Curtis CE, Ernst T, Zoi K, Zoi C, McGuire C, Kreil S, Jones A, Score J, Metzgeroth G, Oscier D, Hall A, Brandts C, Serve H, Reiter A, Chase AJ,

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Blood 113(24):6182-92, 2009 Jun 11 - Who cited this? | PubMed ID: 19387008 | Fulltext

JAK2 haplotype is a major risk factor for the development of myeloproliferative neoplasms.

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Jones AV, Chase A, Silver RT, Oscier D, Zoi K, Wang YL, Cario H, Pahl HL, Collins A, Reiter A, Grand F, and Cross NC

Nature genetics 41(4):446-9, 2009 Apr - Who cited this? | PubMed ID: 19287382 | Fulltext

No evidence for increased prevalence of JAK2 V617F in women with a history of recurrent miscarriage.

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Dahabreh IJ, Jones AV, Voulgarelis M, Giannouli S, Zoi C, Alafakis-Tzannatos C, Varla-Leftherioti M, Moutsopoulos HM, Loukopoulos D, Fotiou S, Cross NC, and Zoi K

British journal of haematology 144(5):802-3, 2009 Mar - Who cited this? | PubMed ID: 19036091 | Fulltext

Clonal diversity in the myeloproliferative neoplasms: independent origins of genetically distinct clones.

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Beer PA, Jones AV, Bench AJ, Goday-Fernandez A, Boyd EM, Vaghela KJ, Erber WN, Odeh B, Wright C, McMullin MF, Cullis J, Huntly BJ, Harrison CN, Cross NC, and Green AR

British journal of haematology 144(6):904-8, 2009 Mar - Who cited this? | PubMed ID: 19170680 | Fulltext

Identification of a MYO18A-PDGFRB fusion gene in an eosinophilia-associated atypical myeloproliferative neoplasm with a t(5;17)(q33-34;q11.2).

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Walz C, Haferlach C, Hänel A, Metzgeroth G, Erben P, Gosenca D, Hochhaus A, Cross NC, and Reiter A

Genes, chromosomes & cancer 48(2):179-83, 2009 Feb - Who cited this? | PubMed ID: 19006078 | Fulltext

Imatinib sensitivity as a consequence of a CSF1R-Y571D mutation and CSF1/CSF1R signaling abnormalities in the cell line GDM1.

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Chase A, Schultheis B, Kreil S, Baxter J, Hidalgo-Curtis C, Jones A, Zhang L, Grand FH, Melo JV, and Cross NC

Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 23(2):358-64, 2009 Feb - Who cited this? | PubMed ID: 18971950 | Fulltext

Detection and molecular monitoring of FIP1L1-PDGFRA-positive disease by analysis of patient-specific genomic DNA fusion junctions.

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Score J, Walz C, Jovanovic JV, Jones AV, Waghorn K, Hidalgo-Curtis C, Lin F, Grimwade D, Grand F, Reiter A, and Cross NC

Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 23(2):332-9, 2009 Feb - Who cited this? | PubMed ID: 18987650 | Fulltext

The molecular anatomy of the FIP1L1-PDGFRA fusion gene.

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Walz C, Score J, Mix J, Cilloni D, Roche-Lestienne C, Yeh RF, Wiemels JL, Ottaviani E, Erben P, Hochhaus A, Baccarani M, Grimwade D, Preudhomme C, Apperley J, Martinelli G, Saglio G,

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Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 23(2):271-8, 2009 Feb - Who cited this? | PubMed ID: 18987651 | Fulltext

Safety and efficacy of imatinib in chronic eosinophilic leukaemia and hypereosinophilic syndrome - a phase-II study.

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Metzgeroth G, Walz C, Erben P, Popp H, Schmitt-Graeff A, Haferlach C, Fabarius A, Schnittger S, Grimwade D, Cross NC, Hehlmann R, Hochhaus A, and Reiter A

British journal of haematology 143(5):707-15, 2008 Dec - Who cited this? | PubMed ID: 18950453 | Fulltext

BCR-ABL1-positive CML and BCR-ABL1-negative chronic myeloproliferative disorders: some common and contrasting features.

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Cross NC, Daley GQ, Green AR, Hughes TP, Jamieson C, Manley P, Mughal T, Perrotti D, Radich J, Skoda R, Soverini S, Vainchenker W, Verstovsek S, Villeval JL, and Goldman JM

Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 22(11):1975-89, 2008 Nov - Who cited this? | PubMed ID: 19002192 | Fulltext

Desirable performance characteristics for BCR-ABL measurement on an international reporting scale to allow consistent interpretation of individual patient response and comparison of response rates between clinical trials.

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Branford S, Fletcher L, Cross NC, Müller MC, Hochhaus A, Kim DW, Radich JP, Saglio G, Pane F, Kamel-Reid S, Wang YL, Press RD, Lynch K, Rudzki Z, Goldman JM, and Hughes T

Blood 112(8):3330-8, 2008 Oct 15 - Who cited this? | PubMed ID: 18684859 | Fulltext

Rapid identification of JAK2 exon 12 mutations using high resolution melting analysis.

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Jones AV, Cross NC, White HE, Green AR, and Scott LM

Haematologica 93(10):1560-4, 2008 Oct - Who cited this? | PubMed ID: 18698085 | Fulltext

Evolutional change of karyotype with t(8;9)(p22;p24) and HLA-DR immunophenotype in relapsed acute myeloid leukemia.

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Huang KP, Chase AJ, Cross NC, Reiter A, Li TY, Wang TF, Chu SC, Lu XY, Li CC, and Kao RH

International journal of hematology, 2008 Jul 2 - Who cited this? | PubMed ID: 18594780 | Fulltext

Fibroblast Growth Factor Receptor and Platelet-Derived Growth Factor Receptor Abnormalities in Eosinophilic Myeloproliferative Disorders.

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Cross NC and Reiter A

Acta haematologica 119(4):199, 2008 Jun 20 - Who cited this? | PubMed ID: 18566537 | Fulltext

Comparison of mutated ABL1 and JAK2 as oncogenes and drug targets in myeloproliferative disorders.

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Walz C, Cross NC, Van Etten RA, and Reiter A

Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, 2008 Jun 5 - Who cited this? | PubMed ID: 18528425 | Fulltext

JAK2 Mutations are present in all cases of polycythemia vera.

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Wang YL, Vandris K, Jones A, Cross NC, Christos P, Adriano F, and Silver RT

Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 22(6):1289, 2008 Jun - Who cited this? | PubMed ID: 18079740 | Fulltext

The t(1;9)(p34;q34) and t(8;12)(p11;q15) fuse pre-mRNA processing proteins SFPQ (PSF) and CPSF6 to ABL and FGFR1.

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Hidalgo-Curtis C, Chase A, Drachenberg M, Roberts MW, Finkelstein JZ, Mould S, Oscier D, Cross NC, and Grand FH

Genes, chromosomes & cancer 47(5):379-85, 2008 May - Who cited this? | PubMed ID: 18205209 | Fulltext

Hitchhikers' guide to the leukemia genome.

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Cross NC

Blood 111(9):4428-9, 2008 May 1 - Who cited this? | PubMed ID: 18441244 | Fulltext

International standardisation of quantitative real-time RT-PCR for BCR-ABL.

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Cross NC, Hughes TP, Hochhaus A, and Goldman JM

Leukemia research 32(3):505-6, 2008 Mar - Who cited this? | PubMed ID: 17512589 | Fulltext

No evidence for amplification of V617F JAK2 in myeloproliferative disorders.

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Jones AV, Bunyan DJ, and Cross NC

Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 21(12):2561-3, 2007 Dec - Who cited this? | PubMed ID: 17611555 | Fulltext

The severity of FIP1L1-PDGFRA-positive chronic eosinophilic leukaemia is associated with polymorphic variation at the IL5RA locus.

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Burgstaller S, Kreil S, Waghorn K, Metzgeroth G, Preudhomme C, Zoi K, White H, Cilloni D, Zoi C, Brito-Babapulle F, Walz C, Reiter A, and Cross NC

Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 21(12):2428-32, 2007 Dec - Who cited this? | PubMed ID: 17914408 | Fulltext

Activity of TKI258 against primary cells and cell lines with FGFR1 fusion genes associated with the 8p11 myeloproliferative syndrome.

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Chase A, Grand FH, and Cross NC

Blood 110(10):3729-34, 2007 Nov 15 - Who cited this? | PubMed ID: 17698633 | Fulltext

Methylation-sensitive high-resolution melting-curve analysis of the SNRPN gene as a diagnostic screen for Prader-Willi and Angelman syndromes.

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White HE, Hall VJ, and Cross NC

Clinical chemistry 53(11):1960, 2007 Nov - Who cited this? | PubMed ID: 17890436 | Fulltext

Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma.

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Jenner MW, Leone PE, Walker BA, Ross FM, Johnson DC, Gonzalez D, Chiecchio L, Dachs Cabanas E, Dagrada GP, Nightingale M, Protheroe RK, Stockley D, Else M, Dickens NJ, Cross NC, Davies FE,

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Blood 110(9):3291-300, 2007 Nov 1 - Who cited this? | PubMed ID: 17609426 | Fulltext

A constitutively active SPTBN1-FLT3 fusion in atypical chronic myeloid leukemia is sensitive to tyrosine kinase inhibitors and immunotherapy.

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Grand FH, Iqbal S, Zhang L, Russell NH, Chase A, and Cross NC

Experimental hematology 35(11):1723-7, 2007 Nov - Who cited this? | PubMed ID: 17764812 | Fulltext

Diagnostic and therapeutic management of eosinophilia-associated chronic myeloproliferative disorders.

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Reiter A, Grimwade D, and Cross NC

Haematologica 92(9):1153-8, 2007 Sep - Who cited this? | PubMed ID: 17768117 | Fulltext

Heterogeneous prognostic impact of derivative chromosome 9 deletions in chronic myelogenous leukemia.

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Kreil S, Pfirrmann M, Haferlach C, Waghorn K, Chase A, Hehlmann R, Reiter A, Hochhaus A, Cross NC, and German Chronic Myelogenous Leukemia (CML) Study Group

Blood 110(4):1283-90, 2007 Aug 15 - Who cited this? | PubMed ID: 17456720 | Fulltext

A novel ETV6-PDGFRB fusion transcript missed by standard screening in a patient with an imatinib responsive chronic myeloproliferative disease.

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Curtis CE, Grand FH, Waghorn K, Sahoo TP, George J, and Cross NC

Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 21(8):1839-41, 2007 Aug - Who cited this? | PubMed ID: 17508004 | Fulltext

Two novel imatinib-responsive PDGFRA fusion genes in chronic eosinophilic leukaemia.

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Curtis CE, Grand FH, Musto P, Clark A, Murphy J, Perla G, Minervini MM, Stewart J, Reiter A, and Cross NC

British journal of haematology 138(1):77, 2007 Jul - Who cited this? | PubMed ID: 17555450 | Fulltext

JAK2-V617F mutation in a patient with Philadelphia-chromosome-positive chronic myeloid leukaemia.

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Krämer A, Reiter A, Kruth J, Erben P, Hochhaus A, Müller M, Cross NC, Jones AV, Ho AD, and Hensel M

The lancet oncology 8(7):658, 2007 Jul - Who cited this? | PubMed ID: 17613428 | Fulltext

Chronic myeloid leukemia--some topical issues.

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Mughal T, Cortes J, Cross NC, Donato N, Hantschel O, Jabbour E, Kantarjian H, Melo JV, Skorski T, Silver RT, and Goldman JM

Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 21(7):1347-52, 2007 Jul - Who cited this? | PubMed ID: 17495971 | Fulltext

Recurrent finding of the FIP1L1-PDGFRA fusion gene in eosinophilia-associated acute myeloid leukemia and lymphoblastic T-cell lymphoma.

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Metzgeroth G, Walz C, Score J, Siebert R, Schnittger S, Haferlach C, Popp H, Haferlach T, Erben P, Mix J, Müller MC, Beneke H, Müller L, Del Valle F, Aulitzky WE, Wittkowsky G,

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Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 21(6):1183, 2007 Jun - Who cited this? | PubMed ID: 17377585 | Fulltext

Low-dose imatinib mesylate leads to rapid induction of major molecular responses and achievement of complete molecular remission in FIP1L1-PDGFRA-positive chronic eosinophilic leukemia.

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Jovanovic JV, Score J, Waghorn K, Cilloni D, Gottardi E, Metzgeroth G, Erben P, Popp H, Walz C, Hochhaus A, Roche-Lestienne C, Preudhomme C, Solomon E, Apperley J, Rondoni M, Ottaviani E,

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Blood 109(11):4635, 2007 Jun 1 - Who cited this? | PubMed ID: 17299092 | Fulltext

Amplification refractory mutation system, a highly sensitive and simple polymerase chain reaction assay, for the detection of JAK2 V617F mutation in chronic myeloproliferative disorders.

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Chen Q, Lu P, Jones AV, Cross NC, Silver RT, and Wang YL

The Journal of molecular diagnostics : JMD 9(2):272-6, 2007 Apr - Who cited this? | PubMed ID: 17384221 | Fulltext

FIP1L1-PDGFRA in chronic eosinophilic leukemia and BCR-ABL1 in chronic myeloid leukemia affect different leukemic cells.

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Crescenzi B, Chase A, Starza RL, Beacci D, Rosti V, Gallì A, Specchia G, Martelli MF, Vandenberghe P, Cools J, Jones AV, Cross NC, Marynen P, and Mecucci C

Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 21(3):397, 2007 Mar - Who cited this? | PubMed ID: 17215855 | Fulltext

Characterization of three new imatinib-responsive fusion genes in chronic myeloproliferative disorders generated by disruption of the platelet-derived growth factor receptor beta gene.

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Walz C, Metzgeroth G, Haferlach C, Schmitt-Graeff A, Fabarius A, Hagen V, Prümmer O, Rauh S, Hehlmann R, Hochhaus A, Cross NC, and Reiter A

Haematologica 92(2):163-9, 2007 Feb - Who cited this? | PubMed ID: 17296564 | Fulltext

Tyrosine kinases as therapeutic targets in BCR-ABL negative chronic myeloproliferative disorders.

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Reiter A, Walz C, and Cross NC

Current drug targets 8(2):205-16, 2007 Feb - Who cited this? | PubMed ID: 17305499 | Fulltext

Simultaneous MLPA-based multiplex point mutation and deletion analysis of the dystrophin gene.

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Bunyan DJ, Skinner AC, Ashton EJ, Sillibourne J, Brown T, Collins AL, Cross NC, Harvey JF, and Robinson DO

Molecular biotechnology 35(2):135-40, 2007 Feb - Who cited this? | PubMed ID: 17435279 | Fulltext

Evaluation of JAK2 in B and T cell neoplasms: identification of JAK2(V617F) mutation of undetermined significance (JMUS) in the bone marrow of three individuals.

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Wang YL, Lee JW, Kui JS, Chadburn A, Cross NC, Knowles DM, and Coleman M

Acta haematologica 118(4):209, 2007 - Who cited this? | PubMed ID: 18032883 | Fulltext

Durable responses to imatinib in patients with PDGFRB fusion gene-positive and BCR-ABL-negative chronic myeloproliferative disorders.

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David M, Cross NC, Burgstaller S, Chase A, Curtis C, Dang R, Gardembas M, Goldman JM, Grand F, Hughes G, Huguet F, Lavender L, McArthur GA, Mahon FX, Massimini G, Melo J,

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Blood 109(1):61-4, 2007 Jan 1 - Who cited this? | PubMed ID: 16960151 | Fulltext

Chronic myeloproliferative disorders: the role of tyrosine kinases in pathogenesis, diagnosis and therapy.

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Macdonald D and Cross NC

Pathobiology : journal of immunopathology, molecular and cellular biology 74(2):81-8, 2007 - Who cited this? | PubMed ID: 17587879 | Fulltext

Rationale for the recommendations for harmonizing current methodology for detecting BCR-ABL transcripts in patients with chronic myeloid leukaemia.

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Branford S, Cross NC, Hochhaus A, Radich J, Saglio G, Kaeda J, Goldman J, and Hughes T

Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 20(11):1925-30, 2006 Nov - Who cited this? | PubMed ID: 16990771 | Fulltext

JAK2V617F mutational frequency in polycythemia vera: 100%, >90%, less?.

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Verstovsek S, Silver RT, Cross NC, and Tefferi A

Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 20(11):2067, 2006 Nov - Who cited this? | PubMed ID: 16990780 | Fulltext

Transient response to imatinib in a chronic eosinophilic leukemia associated with ins(9;4)(q33;q12q25) and a CDK5RAP2-PDGFRA fusion gene.

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Walz C, Curtis C, Schnittger S, Schultheis B, Metzgeroth G, Schoch C, Lengfelder E, Erben P, Müller MC, Haferlach T, Hochhaus A, Hehlmann R, Cross NC, and Reiter A

Genes, chromosomes & cancer 45(10):950-6, 2006 Oct - Who cited this? | PubMed ID: 16845659 | Fulltext

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