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Papers authored by Chung DC

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Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial.

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Maguire AM, High KA, Auricchio A, Wright JF, Pierce EA, Testa F, Mingozzi F, Bennicelli JL, Ying GS, Rossi S, Fulton A, Marshall KA, Banfi S, Chung DC, Morgan JI, Hauck B,

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Lancet 374(9701):1597-605, 2009 Nov 7 - Who cited this? | PubMed ID: 19854499 | Fulltext

Oncogenic KRAS and BRAF differentially regulate hypoxia-inducible factor-1alpha and -2alpha in colon cancer.

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Kikuchi H, Pino MS, Zeng M, Shirasawa S, and Chung DC

Cancer research 69(21):8499-506, 2009 Nov 1 - Who cited this? | PubMed ID: 19843849 | Fulltext

Direct Evidence that Bevacizumab, an Anti-VEGF Antibody, Up-regulates SDF1{alpha}, CXCR4, CXCL6, and Neuropilin 1 in Tumors from Patients with Rectal Cancer.

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Xu L, Duda DG, di Tomaso E, Ancukiewicz M, Chung DC, Lauwers GY, Samuel R, Shellito P, Czito BG, Lin PC, Poleski M, Bentley R, Clark JW, Willett CG, and Jain RK

Cancer research 69(20):7905-10, 2009 Oct 15 - Who cited this? | PubMed ID: 19826039 | Fulltext

Cost-effectiveness of prophylactic surgery for duodenal cancer in familial adenomatous polyposis.

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Greenblatt WH, Hur C, Knudsen AB, Evans JA, Chung DC, and Gazelle GS

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 18(10):2677-84, 2009 Oct - Who cited this? | PubMed ID: 19789369 | Fulltext

Recent breakthroughs in gene therapy for inherited retinal degeneration.

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Revere KE and Chung DC

Discovery medicine 8(42):125-9, 2009 Oct - Who cited this? | PubMed ID: 19833058 | Fulltext

Recent advances in ocular gene therapy.

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Chung DC, Lee V, and Maguire AM

Current opinion in ophthalmology 20(5):377-81, 2009 Sep - Who cited this? | PubMed ID: 19667988 | Fulltext

Colorectal cancer risk perception on the basis of genetic test results in individuals at risk for Lynch syndrome.

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Grover S, Stoffel EM, Mercado RC, Ford BM, Kohlman WK, Shannon KM, Conrad PG, Blanco AM, Terdiman JP, Gruber SB, Chung DC, and Syngal S

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 27(24):3981-6, 2009 Aug 20 - Who cited this? | PubMed ID: 19620492 | Fulltext

An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia.

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Benita Y, Kikuchi H, Smith AD, Zhang MQ, Chung DC, and Xavier RJ

Nucleic acids research 37(14):4587-602, 2009 Aug - Who cited this? | PubMed ID: 19491311 | Fulltext

Efficacy, safety, and biomarkers of neoadjuvant bevacizumab, radiation therapy, and fluorouracil in rectal cancer: a multidisciplinary phase II study.

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Willett CG, Duda DG, di Tomaso E, Boucher Y, Ancukiewicz M, Sahani DV, Lahdenranta J, Chung DC, Fischman AJ, Lauwers GY, Shellito P, Czito BG, Wong TZ, Paulson E, Poleski M, Vujaskovic Z,

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Journal of clinical oncology : official journal of the American Society of Clinical Oncology 27(18):3020-6, 2009 Jun 20 - Who cited this? | PubMed ID: 19470921 | Fulltext

Deficient DNA mismatch repair is common in lynch syndrome-associated colorectal adenomas.

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Pino MS, Mino-Kenudson M, Wildemore BM, Ganguly A, Batten J, Sperduti I, Iafrate AJ, and Chung DC

The Journal of molecular diagnostics : JMD 11(3):238-47, 2009 May - Who cited this? | PubMed ID: 19324997 | Fulltext

Five-year efficacy and safety analysis of the Adenoma Prevention with Celecoxib Trial.

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Bertagnolli MM, Eagle CJ, Zauber AG, Redston M, Breazna A, Kim K, Tang J, Rosenstein RB, Umar A, Bagheri D, Collins NT, Burn J, Chung DC, Dewar T, Foley TR, Hoffman N,

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Cancer prevention research (Philadelphia, Pa.) 2(4):310-21, 2009 Apr - Who cited this? | PubMed ID: 19336730 | Fulltext

HIF-1alpha and HIF-2alpha have divergent roles in colon cancer.

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Imamura T, Kikuchi H, Herraiz MT, Park DY, Mizukami Y, Mino-Kenduson M, Lynch MP, Rueda BR, Benita Y, Xavier RJ, and Chung DC

International journal of cancer. Journal international du cancer 124(4):763-71, 2009 Feb 15 - Who cited this? | PubMed ID: 19030186 | Fulltext

Stool DNA testing and colon cancer prevention: another step forward.

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Chung DC

Annals of internal medicine 149(7):509-10, 2008 Oct 7 - Who cited this? | PubMed ID: 18838731 | Fulltext

Priorities for improving the management of gastroenteropancreatic neuroendocrine tumors.

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Modlin IM, Moss SF, Chung DC, Jensen RT, and Snyderwine E

Journal of the National Cancer Institute 100(18):1282-9, 2008 Sep 17 - Who cited this? | PubMed ID: 18780869 | Fulltext

Hoxc6 Is Overexpressed in Gastrointestinal Carcinoids and Interacts With JunD to Regulate Tumor Growth.

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Fujiki K, Duerr EM, Kikuchi H, Ng A, Xavier RJ, Mizukami Y, Imamura T, Kulke MH, and Chung DC

Gastroenterology 135(3):907-916.e2, 2008 Sep - Who cited this? | PubMed ID: 18655788 | Fulltext

Sonic hedgehog derived from human pancreatic cancer cells augments angiogenic function of endothelial progenitor cells.

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Yamazaki M, Nakamura K, Mizukami Y, Ii M, Sasajima J, Sugiyama Y, Nishikawa T, Nakano Y, Yanagawa N, Sato K, Maemoto A, Tanno S, Okumura T, Karasaki H, Kono T, Fujiya M,

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Cancer science 99(6):1131, 2008 Jun - Who cited this? | PubMed ID: 18422746 | Fulltext

Sharing genetic test results in Lynch syndrome: communication with close and distant relatives.

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Stoffel EM, Ford B, Mercado RC, Punglia D, Kohlmann W, Conrad P, Blanco A, Shannon KM, Powell M, Gruber SB, Terdiman J, Chung DC, and Syngal S

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 6(3):333-8, 2008 Mar - Who cited this? | PubMed ID: 18258490 | Fulltext

Defining molecular classifications and targets in gastroenteropancreatic neuroendocrine tumors through DNA microarray analysis.

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Duerr EM, Mizukami Y, Ng A, Xavier RJ, Kikuchi H, Deshpande V, Warshaw AL, Glickman J, Kulke MH, and Chung DC

Endocrine-related cancer 15(1):243-56, 2008 Mar - Who cited this? | PubMed ID: 18310291 | Fulltext

Mechanisms of Cables 1 gene inactivation in human ovarian cancer development.

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Sakamoto H, Friel AM, Wood AW, Guo L, Ilic A, Seiden MV, Chung DC, Lynch MP, Serikawa T, Munro E, Oliva E, Orsulic S, Kirley SD, Foster R, Zukerberg LR, and Rueda BR

Cancer biology & therapy 7(2):180, 2008 Feb - Who cited this? | PubMed ID: 18059193 | Fulltext

Gastroenteropancreatic neuroendocrine tumours.

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Modlin IM, Oberg K, Chung DC, Jensen RT, de Herder WW, Thakker RV, Caplin M, Delle Fave G, Kaltsas GA, Krenning EP, Moss SF, Nilsson O, Rindi G, Salazar R, Ruszniewski P, and Sundin A

The lancet oncology 9(1):61-72, 2008 Jan - Who cited this? | PubMed ID: 18177818 | Fulltext

Pseudocoarctation of the aorta associated with the anomalous origin of the left vertebral artery: a case report.

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Son JS, Hong KB, and Chung DC

Korean journal of radiology : official journal of the Korean Radiological Society 9(3):283-5, 2008 - Who cited this? | PubMed ID: 18525233 | Fulltext

Expression of CD95 and CD95L on astrocytes in the CA1 area of the immature rat hippocampus after hypoxia-ischemia injury.

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Kim MJ, Lim HS, Yoo YB, Lee YI, Hahm DH, Lee HJ, Jung KW, Kim JW, Yoe SM, Chung DC, and Chang YP

Comparative medicine 57(6):581-9, 2007 Dec - Who cited this? | PubMed ID: 18246871 | Fulltext

The cables gene on chromosome 18q is silenced by promoter hypermethylation and allelic loss in human colorectal cancer.

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Park do Y, Sakamoto H, Kirley SD, Ogino S, Kawasaki T, Kwon E, Mino-Kenudson M, Lauwers GY, Chung DC, Rueda BR, and Zukerberg LR

The American journal of pathology 171(5):1509-19, 2007 Nov - Who cited this? | PubMed ID: 17982127 | Fulltext

Hypoxia inducible factor-1 independent pathways in tumor angiogenesis.

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Mizukami Y, Kohgo Y, and Chung DC

Clinical cancer research : an official journal of the American Association for Cancer Research 13(19):5670-4, 2007 Oct 1 - Who cited this? | PubMed ID: 17908955 | Fulltext

Knowledge and attitudes about microsatellite instability testing among high-risk individuals diagnosed with colorectal cancer.

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Manne SL, Chung DC, Weinberg DS, Vig HS, Catts Z, Cabral MK, Shannon K, and Meropol NJ

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 16(10):2110-7, 2007 Oct - Who cited this? | PubMed ID: 17932359 | Fulltext

Microsatellite instability is frequently observed in rectal cancer and influenced by neoadjuvant chemoradiation.

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Choi MY, Lauwers GY, Hur C, Willett CG, and Chung DC

International journal of radiation oncology, biology, physics 68(5):1584, 2007 Aug 1 - Who cited this? | PubMed ID: 17674996 | Fulltext

Case records of the Massachusetts General Hospital. Case 22-2007. A woman with a family history of gastric and breast cancer.

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Chung DC, Yoon SS, Lauwers GY, and Patel D

The New England journal of medicine 357(3):283-91, 2007 Jul 19 - Who cited this? | PubMed ID: 17634464 | Fulltext

Pressure on the neck during laryngoscopy.

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Ho AM and Chung DC

Paediatric anaesthesia 17(6):601; author reply 601, 2007 Jun - Who cited this? | PubMed ID: 17498031 | Fulltext

Prevalence of thyroid cancer in familial adenomatous polyposis syndrome and the role of screening ultrasound examinations.

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Herraiz M, Barbesino G, Faquin W, Chan-Smutko G, Patel D, Shannon KM, Daniels GH, and Chung DC

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 5(3):367-73, 2007 Mar - Who cited this? | PubMed ID: 17258512 | Fulltext

Molecular genetics of neuroendocrine tumors.

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Duerr EM and Chung DC

Best practice & research. Clinical endocrinology & metabolism 21(1):1-14, 2007 Mar - Who cited this? | PubMed ID: 17382262 | Fulltext

Gene transfer to ocular stem cells by early gestational intraamniotic injection of lentiviral vector.

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Endo M, Zoltick PW, Chung DC, Bennett J, Radu A, Muvarak N, and Flake AW

Molecular therapy : the journal of the American Society of Gene Therapy 15(3):579-87, 2007 Mar - Who cited this? | PubMed ID: 17245352 | Fulltext

The management of small polyps found by virtual colonoscopy: results of a decision analysis.

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Hur C, Chung DC, Schoen RE, and Gazelle GS

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 5(2):237-44, 2007 Feb - Who cited this? | PubMed ID: 17296532 | Fulltext

Hereditary colorectal cancer syndromes: an overview.

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Kwak EL and Chung DC

Clinical colorectal cancer 6(5):340-4, 2007 Jan - Who cited this? | PubMed ID: 17311698 | Fulltext

Case records of the Massachusetts General Hospital. Case 37-2006. A 19-year-old woman with thyroid cancer and lower gastrointestinal bleeding.

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Chung DC, Maher MM, and Faquin WC

The New England journal of medicine 355(22):2349-57, 2006 Nov 30 - Who cited this? | PubMed ID: 17135589 | Fulltext

The serrated polyp comes of age.

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Lauwers GY and Chung DC

Gastroenterology 131(5):1631-4, 2006 Nov - Who cited this? | PubMed ID: 17067594 | Fulltext

Celecoxib for the prevention of sporadic colorectal adenomas.

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Bertagnolli MM, Eagle CJ, Zauber AG, Redston M, Solomon SD, Kim K, Tang J, Rosenstein RB, Wittes J, Corle D, Hess TM, Woloj GM, Boisserie F, Anderson WF, Viner JL, Bagheri D,

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The New England journal of medicine 355(9):873-84, 2006 Aug 31 - Who cited this? | PubMed ID: 16943400 | Fulltext

Hypoxic regulation of vascular endothelial growth factor through the induction of phosphatidylinositol 3-kinase/Rho/ROCK and c-Myc.

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Mizukami Y, Fujiki K, Duerr EM, Gala M, Jo WS, Zhang X, and Chung DC

The Journal of biological chemistry 281(20):13957, 2006 May 19 - Who cited this? | PubMed ID: 16543245 | Fulltext

Dynamic airflow limitation after topical anaesthesia of the upper airway.

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Ho AM, Chung DC, Karmakar MK, Gomersall CD, Peng Z, and Tay BA

Anaesthesia and intensive care 34(2):211-5, 2006 Apr - Who cited this? | PubMed ID: 16617642 | Fulltext

Colorectal cancer screening: today and tomorrow.

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Hung KE and Chung DC

Southern medical journal 99(3):240-6; quiz 247-9, 2006 Mar - Who cited this? | PubMed ID: 16553098 | Fulltext

Wnt signaling can repress thrombospondin-1 expression in colonic tumorigenesis.

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Jo WS, Mizukami Y, Duerr EM, Zukerberg LR, and Chung DC

Cancer biology & therapy 4(12):1361-6, 2005 Dec - Who cited this? | PubMed ID: 16258261 | Fulltext

Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients.

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Willett CG, Boucher Y, Duda DG, di Tomaso E, Munn LL, Tong RT, Kozin SV, Petit L, Jain RK, Chung DC, Sahani DV, Kalva SP, Cohen KS, Scadden DT, Fischman AJ, Clark JW,

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Journal of clinical oncology : official journal of the American Society of Clinical Oncology 23(31):8136-9, 2005 Nov 1 - Who cited this? | PubMed ID: 16258121 | Fulltext

Case records of the Massachusetts General Hospital. Case 33-2005. A 43-year-old man with lower gastrointestinal bleeding.

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Korzenik J, Chung DC, Digumarthy S, and Badizadegan K

The New England journal of medicine 353(17):1836-44, 2005 Oct 27 - Who cited this? | PubMed ID: 16251540 | Fulltext

Correlation of polyp number and family history of colon cancer with germline MYH mutations.

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Jo WS, Bandipalliam P, Shannon KM, Niendorf KB, Chan-Smutko G, Hur C, Syngal S, and Chung DC

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 3(10):1022-8, 2005 Oct - Who cited this? | PubMed ID: 16234049 | Fulltext

Induction of interleukin-8 preserves the angiogenic response in HIF-1alpha-deficient colon cancer cells.

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Mizukami Y, Jo WS, Duerr EM, Gala M, Li J, Zhang X, Zimmer MA, Iliopoulos O, Zukerberg LR, Kohgo Y, Lynch MP, Rueda BR, and Chung DC

Nature medicine 11(9):992, 2005 Sep - Who cited this? | PubMed ID: 16127434 | Fulltext

The Cables gene on chromosome 18Q regulates colon cancer progression in vivo.

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Kirley SD, D'Apuzzo M, Lauwers GY, Graeme-Cook F, Chung DC, and Zukerberg LR

Cancer biology & therapy 4(8):861-3, 2005 Aug - Who cited this? | PubMed ID: 16210915 | Fulltext

Oncogenic K-ras stimulates Wnt signaling in colon cancer through inhibition of GSK-3beta.

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Li J, Mizukami Y, Zhang X, Jo WS, and Chung DC

Gastroenterology 128(7):1907-18, 2005 Jun - Who cited this? | PubMed ID: 15940626 | Fulltext

Increased growth rate, delayed senescense and decreased serum dependence characterize cables-deficient cells.

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Kirley SD, Rueda BR, Chung DC, and Zukerberg LR

Cancer biology & therapy 4(6):654-8, 2005 Jun - Who cited this? | PubMed ID: 15908791 | Fulltext

Low rate of microsatellite instability in young patients with adenomas: reassessing the Bethesda guidelines.

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Velayos FS, Allen BA, Conrad PG, Gum J, Kakar S, Chung DC, Truta B, Sleisenger MH, Kim YS, and Terdiman JP

The American journal of gastroenterology 100(5):1143-9, 2005 May - Who cited this? | PubMed ID: 15842591 | Fulltext

Mutational analysis of PPARG as a candidate tumour suppressor gene in enteropancreatic endocrine tumours.

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Costa-Guda J, Rosen ED, Jensen RT, Chung DC, and Arnold A

Clinical endocrinology 62(5):603-6, 2005 May - Who cited this? | PubMed ID: 15853832 | Fulltext

Overexpression of cyclin D1 in pancreatic beta-cells in vivo results in islet hyperplasia without hypoglycemia.

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Zhang X, Gaspard JP, Mizukami Y, Li J, Graeme-Cook F, and Chung DC

Diabetes 54(3):712, 2005 Mar - Who cited this? | PubMed ID: 15734847 | Fulltext

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