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Papers authored by Chahine M

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Cardiac metabolic state and Brugada syndrome: a link revealed.

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Chahine M

Circulation research 105(8):721-3, 2009 Oct 9 - Who cited this? | PubMed ID: 19815826 | Fulltext

Bioavailability of alpha-linolenic acid from flaxseed diets as a function of the age of the subject.

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Patenaude A, Rodriguez-Leyva D, Edel AL, Dibrov E, Dupasquier CM, Austria JA, Richard MN, Chahine MN, Malcolmson LJ, and Pierce GN

European journal of clinical nutrition 63(9):1123-9, 2009 Sep - Who cited this? | PubMed ID: 19584895 | Fulltext

Therapeutic targeting of nuclear protein import in pathological cell conditions.

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Chahine MN and Pierce GN

Pharmacological reviews 61(3):358-72, 2009 Sep - Who cited this? | PubMed ID: 19805478 | Fulltext

Characterization of novel KCNH2 mutations in type 2 long QT syndrome manifesting as seizures.

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Keller DI, Grenier J, Christé G, Dubouloz F, Osswald S, Brink M, Ficker E, and Chahine M

The Canadian journal of cardiology 25(8):455-62, 2009 Aug - Who cited this? | PubMed ID: 19668779 | Fulltext

Effect of preslaughter feeding and ractopamine hydrochloride supplementation on growth performance, carcass characteristics, and end product quality in market dairy cows.

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Allen JD, Ahola JK, Chahine M, Szasz JI, Hunt CW, Schneider CS, Murdoch GK, and Hill RA

Journal of animal science 87(7):2400-8, 2009 Jul - Who cited this? | PubMed ID: 19359500 | Fulltext

Contribution of Long-QT Syndrome Genetic Variants in Sudden Infant Death Syndrome.

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Millat G, Kugener B, Chevalier P, Chahine M, Huang H, Malicier D, Rodriguez-Lafrasse C, and Rousson R

Pediatric cardiology 30(4):502-9, 2009 May - Who cited this? | PubMed ID: 19322600 | Fulltext

Biophysical characterization of a new SCN5A mutation S1333Y in a SIDS infant linked to long QT syndrome.

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Huang H, Millat G, Rodriguez-Lafrasse C, Rousson R, Kugener B, Chevalier P, and Chahine M

FEBS letters 583(5):890-6, 2009 Mar 4 - Who cited this? | PubMed ID: 19302788 | Fulltext

Oxidized LDL affects smooth muscle cell growth through MAPK-mediated actions on nuclear protein import.

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Chahine MN, Blackwood DP, Dibrov E, Richard MN, and Pierce GN

Journal of molecular and cellular cardiology 46(3):431-41, 2009 Mar - Who cited this? | PubMed ID: 19010332 | Fulltext

Assessment of management and basic beef quality assurance practices on Idaho dairies.

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Glaze JB and Chahine M

Journal of dairy science 92(3):1265-71, 2009 Mar - Who cited this? | PubMed ID: 19233819 | Fulltext

Gain-of-function mutation of Nav1.5 in atrial fibrillation enhances cellular excitability and lowers the threshold for action potential firing.

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Li Q, Huang H, Liu G, Lam K, Rutberg J, Green MS, Birnie DH, Lemery R, Chahine M, and Gollob MH

Biochemical and biophysical research communications 380(1):132-7, 2009 Feb 27 - Who cited this? | PubMed ID: 19167345 | Fulltext

Phosphorylation of the Consensus Sites of Protein Kinase A on {alpha}1D L-type Calcium Channel.

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Ramadan O, Qu Y, Wadgaonkar R, Baroudi G, Karnabi E, Chahine M, and Boutjdir M

The Journal of biological chemistry 284(8):5042-9, 2009 Feb 20 - Who cited this? | PubMed ID: 19074150 | Fulltext

In utero onset of long QT syndrome with atrioventricular block and spontaneous or lidocaine-induced ventricular tachycardia: Compound effects of hERG pore region mutation and SCN5A N-terminus variant.

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Lin MT, Wu MH, Chang CC, Chiu SN, Thériault O, Huang H, Christé G, Ficker E, and Chahine M

Heart rhythm : the official journal of the Heart Rhythm Society 5(11):1567-74, 2008 Nov - Who cited this? | PubMed ID: 18848812 | Fulltext

A new C-terminal hERG mutation A915fs+47X associated with symptomatic LQT2 and auditory-trigger syncope.

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Christé G, Thériault O, Chahine M, Millat G, Rodriguez-Lafrasse C, Rousson R, Deschênes I, Ficker E, and Chevalier P

Heart rhythm : the official journal of the Heart Rhythm Society 5(11):1577-86, 2008 Nov - Who cited this? | PubMed ID: 18984536 | Fulltext

Enzyme Domain Affects the Movement of the Voltage Sensor in Ascidian and Zebrafish Voltage-sensing Phosphatases.

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Hossain MI, Iwasaki H, Okochi Y, Chahine M, Higashijima S, Nagayama K, and Okamura Y

The Journal of biological chemistry 283(26):18248, 2008 Jun 27 - Who cited this? | PubMed ID: 18375390 | Fulltext

Biophysical properties of human nav1.7 splice variants and their regulation by protein kinase a.

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Chatelier A, Dahllund L, Eriksson A, Krupp J, and Chahine M

Journal of neurophysiology 99(5):2241-50, 2008 May - Who cited this? | PubMed ID: 18337362 | Fulltext

Voltage-gated sodium channels in neurological disorders.

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Chahine M, Chatelier A, Babich O, and Krupp JJ

CNS & neurological disorders drug targets 7(2):144-58, 2008 Apr - Who cited this? | PubMed ID: 18537643 | Fulltext

Bioavailability of alpha-linolenic acid in subjects after ingestion of three different forms of flaxseed.

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Austria JA, Richard MN, Chahine MN, Edel AL, Malcolmson LJ, Dupasquier CM, and Pierce GN

Journal of the American College of Nutrition 27(2):214-21, 2008 Apr - Who cited this? | PubMed ID: 18689552 | Fulltext

Ceramide regulation of nuclear protein import.

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Faustino RS, Cheung P, Richard MN, Dibrov E, Kneesch AL, Deniset JF, Chahine MN, Lee K, Blackwood D, and Pierce GN

Journal of lipid research 49(3):654, 2008 Mar - Who cited this? | PubMed ID: 18083977 | Fulltext

Protein kinase C activation inhibits alpha(1D) L-type Ca channel: A single-channel analysis.

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Chahine M, Qu Y, Mancarella S, and Boutjdir M

Pflugers Archiv : European journal of physiology 455(5):913-9, 2008 Feb - Who cited this? | PubMed ID: 17909852 | Fulltext

The occurrence of Brugada syndrome and isolated cardiac conductive disease in the same family could be due to a single SCN5A mutation or to the accidental association of both diseases.

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Six I, Hermida JS, Huang H, Gouas L, Fressart V, Benammar N, Hainque B, Denjoy I, Chahine M, and Guicheney P

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 10(1):79-85, 2008 Jan - Who cited this? | PubMed ID: 18156160 | Fulltext

Changes in action potentials and intracellular ionic homeostasis in a ventricular cell model related to a persistent sodium current in SCN5A mutations underlying LQT3.

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Christé G, Chahine M, Chevalier P, and Pásek M

Progress in biophysics and molecular biology 96(1-3):281-93, 2008 - Who cited this? | PubMed ID: 17892895 | Fulltext

The Brugada syndrome in Canada: A unique French-Canadian experience.

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Champagne J, Philippon F, Gilbert M, Molin F, Blier L, Nault I, Sarrazin JF, Charbonneau L, Dufort L, Drolet B, Chahine M, and O'hara GE

The Canadian journal of cardiology 23 Suppl B:71B-5B, 2007 Oct - Who cited this? | PubMed ID: 17932591 | Fulltext

Lidocaine promotes the trafficking and functional expression of Na(v)1.8 sodium channels in mammalian cells.

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Zhao J, Ziane R, Chatelier A, O'leary ME, and Chahine M

Journal of neurophysiology 98(1):467-77, 2007 Jul - Who cited this? | PubMed ID: 17507497 | Fulltext

Acidic residues on the voltage-sensor domain determine the activation of the NaChBac sodium channel.

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Blanchet J, Pilote S, and Chahine M

Biophysical journal 92(10):3513-23, 2007 May 15 - Who cited this? | PubMed ID: 17325004 | Fulltext

Expression of skeletal muscle Na(V)1.4 Na channel isoform in canine cardiac Purkinje myocytes.

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Qu Y, Karnabi E, Chahine M, Vassalle M, and Boutjdir M

Biochemical and biophysical research communications 355(1):28-33, 2007 Mar 30 - Who cited this? | PubMed ID: 17286959 | Fulltext

Effect of dietary hempseed intake on cardiac ischemia-reperfusion injury.

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Al-Khalifa A, Maddaford TG, Chahine MN, Austria JA, Edel AL, Richard MN, Ander BP, Gavel N, Kopilas M, Ganguly R, Ganguly PK, and Pierce GN

American journal of physiology. Regulatory, integrative and comparative physiology 292(3):R1198-203, 2007 Mar - Who cited this? | PubMed ID: 17122327 | Fulltext

Accessibility of four arginine residues on the S4 segment of the Bacillus halodurans sodium channel.

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Blanchet J and Chahine M

The Journal of membrane biology 215(2-3):169-80, 2007 Feb - Who cited this? | PubMed ID: 17568977 | Fulltext

A novel mutation in the SCN5A gene is associated with Brugada syndrome.

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Shin DJ, Kim E, Park SB, Jang WC, Bae Y, Han J, Jang Y, Joung B, Lee MH, Kim SS, Huang H, Chahine M, and Yoon SK

Life sciences 80(8):716-24, 2007 Jan 30 - Who cited this? | PubMed ID: 17141278 | Fulltext

[A channel without pore? The primary structure of a proton permeable channel is finally revealed].

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Chahine M, Blanchet J, El Chemaly A, and Bois P

Medecine sciences : M/S 22(11):930-1, 2006 Nov - Who cited this? | PubMed ID: 17101093 | Fulltext

Protein kinase C activation inhibits Cav1.3 calcium channel at NH2-terminal serine 81 phosphorylation site.

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Baroudi G, Qu Y, Ramadan O, Chahine M, and Boutjdir M

American journal of physiology. Heart and circulatory physiology 291(4):H1614-22, 2006 Oct - Who cited this? | PubMed ID: 16973824 | Fulltext

SCN5A polymorphism restores trafficking of a Brugada syndrome mutation on a separate gene.

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Poelzing S, Forleo C, Samodell M, Dudash L, Sorrentino S, Anaclerio M, Troccoli R, Iacoviello M, Romito R, Guida P, Chahine M, Pitzalis M, and Deschênes I

Circulation 114(5):368, 2006 Aug 1 - Who cited this? | PubMed ID: 16864729 | Fulltext

ETB receptor dependent alteration in aortic responses to ET-1 in the cardiomyopathic hamster.

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Al-Khoury J, Bkaily G, Chahine M, Jacques D, and D'Orléans-Juste P

Canadian journal of physiology and pharmacology 84(7):787-94, 2006 Jul - Who cited this? | PubMed ID: 16998542 | Fulltext

A novel SCN5A mutation, F1344S, identified in a patient with Brugada syndrome and fever-induced ventricular fibrillation.

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Keller DI, Huang H, Zhao J, Frank R, Suarez V, Delacrétaz E, Brink M, Osswald S, Schwick N, and Chahine M

Cardiovascular research 70(3):521-9, 2006 Jun 1 - Who cited this? | PubMed ID: 16616735 | Fulltext

Nav1.5/R1193Q polymorphism is associated with both long QT and Brugada syndromes.

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Huang H, Zhao J, Barrane FZ, Champagne J, and Chahine M

The Canadian journal of cardiology 22(4):309-13, 2006 Mar 15 - Who cited this? | PubMed ID: 16568155 | Fulltext

Clinical aspects and physiopathology of Brugada syndrome: review of current concepts.

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Herbert E and Chahine M

Canadian journal of physiology and pharmacology 84(8-9):795-802, 2006 - Who cited this? | PubMed ID: 17111025 | Fulltext

Regulation of Na v channels in sensory neurons.

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Chahine M, Ziane R, Vijayaragavan K, and Okamura Y

Trends in pharmacological sciences 26(10):496-502, 2005 Oct - Who cited this? | PubMed ID: 16125256 | Fulltext

A novel nonsense mutation in the SCN5A gene leads to Brugada syndrome and a silent gene mutation carrier state.

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Keller DI, Barrane FZ, Gouas L, Martin J, Pilote S, Suarez V, Osswald S, Brink M, Guicheney P, Schwick N, and Chahine M

The Canadian journal of cardiology 21(11):925-31, 2005 Sep - Who cited this? | PubMed ID: 16239976 | Fulltext

NHE-1-dependent intracellular sodium overload in hypertrophic hereditary cardiomyopathy: prevention by NHE-1 inhibitor.

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Chahine M, Bkaily G, Nader M, Al-Khoury J, Jacques D, Beier N, and Scholz W

Journal of molecular and cellular cardiology 38(4):571-82, 2005 Apr - Who cited this? | PubMed ID: 15808834 | Fulltext

A novel SCN5A mutation manifests as a malignant form of long QT syndrome with perinatal onset of tachycardia/bradycardia.

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Chang CC, Acharfi S, Wu MH, Chiang FT, Wang JK, Sung TC, and Chahine M

Cardiovascular research 64(2):268-78, 2004 Nov 1 - Who cited this? | PubMed ID: 15485686 | Fulltext

Role of arginine residues on the S4 segment of the Bacillus halodurans Na+ channel in voltage-sensing.

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Chahine M, Pilote S, Pouliot V, Takami H, and Sato C

The Journal of membrane biology 201(1):9-24, 2004 Sep 1 - Who cited this? | PubMed ID: 15635808 | Fulltext

Role of auxiliary beta1-, beta2-, and beta3-subunits and their interaction with Na(v)1.8 voltage-gated sodium channel.

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Vijayaragavan K, Powell AJ, Kinghorn IJ, and Chahine M

Biochemical and biophysical research communications 319(2):531-40, 2004 Jun 25 - Who cited this? | PubMed ID: 15178439 | Fulltext

Differential modulation of Nav1.7 and Nav1.8 peripheral nerve sodium channels by the local anesthetic lidocaine.

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Chevrier P, Vijayaragavan K, and Chahine M

British journal of pharmacology 142(3):576-84, 2004 Jun - Who cited this? | PubMed ID: 15148257 | Fulltext

Modulation of Nav1.7 and Nav1.8 peripheral nerve sodium channels by protein kinase A and protein kinase C.

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Vijayaragavan K, Boutjdir M, and Chahine M

Journal of neurophysiology 91(4):1556-69, 2004 Apr - Who cited this? | PubMed ID: 14657190 | Fulltext

Loss of function associated with novel mutations of the SCN5A gene in patients with Brugada syndrome.

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Baroudi G, Napolitano C, Priori SG, Del Bufalo A, and Chahine M

The Canadian journal of cardiology 20(4):425-30, 2004 Mar 15 - Who cited this? | PubMed ID: 15057319 | Fulltext

The C-terminal region as a modulator of rNa(v)1.7 and rNa(v)1.8 expression levels.

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Vijayaragavan K, Acharfi S, and Chahine M

FEBS letters 559(1-3):39-44, 2004 Feb 13 - Who cited this? | PubMed ID: 14960304 | Fulltext

Genetic analysis of the cardiac sodium channel gene SCN5A in Koreans with Brugada syndrome.

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Shin DJ, Jang Y, Park HY, Lee JE, Yang K, Kim E, Bae Y, Kim J, Kim J, Kim SS, Lee MH, Chahine M, and Yoon SK

Journal of human genetics 49(10):573-8, 2004 - Who cited this? | PubMed ID: 15338453 | Fulltext

Closing and inactivation potentiate the cocaethylene inhibition of cardiac sodium channels by distinct mechanisms.

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O'Leary ME, Digregorio M, and Chahine M

Molecular pharmacology 64(6):1575-85, 2003 Dec - Who cited this? | PubMed ID: 14645689 | Fulltext

A novel mutation in SCN5A, delQKP 1507-1509, causing long QT syndrome: role of Q1507 residue in sodium channel inactivation.

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Keller DI, Acharfi S, Delacrétaz E, Benammar N, Rotter M, Pfammatter JP, Fressart V, Guicheney P, and Chahine M

Journal of molecular and cellular cardiology 35(12):1513-21, 2003 Dec - Who cited this? | PubMed ID: 14654377 | Fulltext

Pathophysiology of Brugada syndrome.

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Chahine M

Journal of cardiovascular electrophysiology 14(11):1257-8; author reply 1258, 2003 Nov - Who cited this? | PubMed ID: 14678148 | Fulltext

Anesthetic management of a patient having a carcinoid syndrome.

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Jabbour-Khoury S, Dabbous A, al-Jazzar M, Rizk M, Chahine M, Khalife M, Ayoub C, and Baraka A

Middle East journal of anesthesiology 17(3):435-47, 2003 Oct - Who cited this? | PubMed ID: 14740596 | Fulltext

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