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Papers authored by Castrillon DH

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FoxO4 Inhibits NF-kappaB and Protects Mice Against Colonic Injury and Inflammation.

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Zhou W, Cao Q, Peng Y, Zhang QJ, Castrillon DH, Depinho RA, and Liu ZP

Gastroenterology 137(4):1403-14, 2009 Oct - Who cited this? | PubMed ID: 19560465 | Fulltext

Kit signaling via PI3K promotes ovarian follicle maturation but is dispensable for primordial follicle activation.

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John GB, Shidler MJ, Besmer P, and Castrillon DH

Developmental biology 331(2):292-9, 2009 Jul 15 - Who cited this? | PubMed ID: 19447101 | Fulltext

Foxo3-/- mice demonstrate reduced numbers of pre-B and recirculating B cells but normal splenic B cell sub-population distribution.

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Hinman RM, Nichols WA, Diaz TM, Gallardo TD, Castrillon DH, and Satterthwaite AB

International immunology 21(7):831-42, 2009 Jul - Who cited this? | PubMed ID: 19502585 | Fulltext

Transcription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells.

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Dejean AS, Beisner DR, Ch'en IL, Kerdiles YM, Babour A, Arden KC, Castrillon DH, DePinho RA, and Hedrick SM

Nature immunology 10(5):504-13, 2009 May - Who cited this? | PubMed ID: 19363483 | Fulltext

Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor.

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Kerdiles YM, Beisner DR, Tinoco R, Dejean AS, Castrillon DH, Depinho RA, and Hedrick SM

Nature immunology 10(2):176-84, 2009 Feb - Who cited this? | PubMed ID: 19136962 | Fulltext

Somatic LKB1 mutations promote cervical cancer progression.

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Wingo SN, Gallardo TD, Akbay EA, Liang MC, Contreras CM, Boren T, Shimamura T, Miller DS, Sharpless NE, Bardeesy N, Kwiatkowski DJ, Schorge JO, Wong KK, and Castrillon DH

PLoS ONE 4(4):e5137, 2009 - Who cited this? | PubMed ID: 19340305 | Fulltext

Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation.

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Dengler HS, Baracho GV, Omori SA, Bruckner S, Arden KC, Castrillon DH, Depinho RA, and Rickert RC

Nature immunology, 2008 Nov 2 - Who cited this? | PubMed ID: 18978794 | Fulltext

Differential roles of telomere attrition in type I and II endometrial carcinogenesis.

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Akbay EA, Contreras CM, Perera SA, Sullivan JP, Broaddus RR, Schorge JO, Ashfaq R, Saboorian H, Wong KK, and Castrillon DH

The American journal of pathology 173(2):536, 2008 Aug - Who cited this? | PubMed ID: 18599611 | Fulltext

DNA methyltransferase loading, but not de novo methylation, is an oocyte-autonomous process stimulated by SCF signalling.

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Lees-Murdock DJ, Lau HT, Castrillon DH, De Felici M, and Walsh CP

Developmental biology, 2008 Jun 25 - Who cited this? | PubMed ID: 18616936 | Fulltext

Foxo3 is a PI3K-dependent molecular switch controlling the initiation of oocyte growth.

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John GB, Gallardo TD, Shirley LJ, and Castrillon DH

Developmental biology, 2008 Jun 20 - Who cited this? | PubMed ID: 18601916 | Fulltext

Telomere dysfunction promotes genome instability and metastatic potential in a K-ras p53 mouse model of lung cancer.

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Perera SA, Maser RS, Xia H, McNamara K, Protopopov A, Chen L, Hezel AF, Kim CF, Bronson RT, Castrillon DH, Chin L, Bardeesy N, Depinho RA, and Wong KK

Carcinogenesis 29(4):747-53, 2008 Apr - Who cited this? | PubMed ID: 18283039 | Fulltext

Loss of Lkb1 provokes highly invasive endometrial adenocarcinomas.

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Contreras CM, Gurumurthy S, Haynie JM, Shirley LJ, Akbay EA, Wingo SN, Schorge JO, Broaddus RR, Wong KK, Bardeesy N, and Castrillon DH

Cancer research 68(3):759-66, 2008 Feb 1 - Who cited this? | PubMed ID: 18245476 | Fulltext

Sequence variation at the human FOXO3 locus: a study of premature ovarian failure and primary amenorrhea.

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Gallardo TD, John GB, Bradshaw K, Welt C, Reijo-Pera R, Vogt PH, Touraine P, Bione S, Toniolo D, Nelson LM, Zinn AR, and Castrillon DH

Human reproduction (Oxford, England) 23(1):216-21, 2008 Jan - Who cited this? | PubMed ID: 17959613 | Fulltext

A Foxo/Notch pathway controls myogenic differentiation and fiber type specification.

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Kitamura T, Kitamura YI, Funahashi Y, Shawber CJ, Castrillon DH, Kollipara R, Depinho RA, Kitajewski J, and Accili D

The Journal of clinical investigation 117(9):2477, 2007 Sep - Who cited this? | PubMed ID: 17717603 | Fulltext

Genomewide discovery and classification of candidate ovarian fertility genes in the mouse.

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Gallardo TD, John GB, Shirley L, Contreras CM, Akbay EA, Haynie JM, Ward SE, Shidler MJ, and Castrillon DH

Genetics 177(1):179-94, 2007 Sep - Who cited this? | PubMed ID: 17660561 | Fulltext

LKB1 modulates lung cancer differentiation and metastasis.

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Ji H, Ramsey MR, Hayes DN, Fan C, McNamara K, Kozlowski P, Torrice C, Wu MC, Shimamura T, Perera SA, Liang MC, Cai D, Naumov GN, Bao L, Contreras CM, Li D,

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Nature 448(7155):807, 2007 Aug 16 - Who cited this? | PubMed ID: 17676035 | Fulltext

Simplifying the preevacuation testing strategy for patients with molar pregnancy.

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Knowles LM, Drake RD, Ashfaq R, Castrillon DH, Miller DS, and Schorge JO

The Journal of reproductive medicine 52(8):685-8, 2007 Aug - Who cited this? | PubMed ID: 17879828 | Fulltext

Viable mice with compound mutations in the Wnt/Dvl pathway antagonists nkd1 and nkd2.

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Zhang S, Cagatay T, Amanai M, Zhang M, Kline J, Castrillon DH, Ashfaq R, Oz OK, and Wharton KA

Molecular and cellular biology 27(12):4454-64, 2007 Jun - Who cited this? | PubMed ID: 17438140 | Fulltext

Generation of a germ cell-specific mouse transgenic Cre line, Vasa-Cre.

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Gallardo T, Shirley L, John GB, and Castrillon DH

Genesis (New York, N.Y. : 2000) 45(6):413-7, 2007 Jun - Who cited this? | PubMed ID: 17551945 | Fulltext

Specificity of the requirement for Foxo3 in primordial follicle activation.

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John GB, Shirley LJ, Gallardo TD, and Castrillon DH

Reproduction (Cambridge, England) 133(5):855-63, 2007 May - Who cited this? | PubMed ID: 17616716 | Fulltext

FoxO4 regulates tumor necrosis factor alpha-directed smooth muscle cell migration by activating matrix metalloproteinase 9 gene transcription.

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Li H, Liang J, Castrillon DH, Depinho RA, Olson EN, and Liu ZP

Molecular and cellular biology 27(7):2676, 2007 Apr - Who cited this? | PubMed ID: 17242183 | Fulltext

FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis.

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Paik JH, Kollipara R, Chu G, Ji H, Xiao Y, Ding Z, Miao L, Tothova Z, Horner JW, Carrasco DR, Jiang S, Gilliland DG, Chin L, Wong WH, Castrillon DH, and Depinho RA

Cell 128(2):309, 2007 Jan 26 - Who cited this? | PubMed ID: 17254969 | Fulltext

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress.

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Tothova Z, Kollipara R, Huntly BJ, Lee BH, Castrillon DH, Cullen DE, McDowell EP, Lazo-Kallanian S, Williams IR, Sears C, Armstrong SA, Passegué E, Depinho RA, and Gilliland DG

Cell 128(2):325, 2007 Jan 26 - Who cited this? | PubMed ID: 17254970 | Fulltext

Foxo transcription factors blunt cardiac hypertrophy by inhibiting calcineurin signaling.

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Ni YG, Berenji K, Wang N, Oh M, Sachan N, Dey A, Cheng J, Lu G, Morris DJ, Castrillon DH, Gerard RD, Rothermel BA, and Hill JA

Circulation 114(11):1159-68, 2006 Sep 12 - Who cited this? | PubMed ID: 16952979 | Fulltext

Germ cell lineage differentiation in non-seminomatous germ cell tumours.

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Honecker F, Stoop H, Mayer F, Bokemeyer C, Castrillon DH, Lau YF, Looijenga LH, and Oosterhuis JW

The Journal of pathology 208(3):395, 2006 Feb - Who cited this? | PubMed ID: 16273510 | Fulltext

Regulation of oxidative stress by the anti-aging hormone klotho.

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Yamamoto M, Clark JD, Pastor JV, Gurnani P, Nandi A, Kurosu H, Miyoshi M, Ogawa Y, Castrillon DH, Rosenblatt KP, and Kuro-o M

The Journal of biological chemistry 280(45):38029-34, 2005 Nov 11 - Who cited this? | PubMed ID: 16186101 | Fulltext

Duration of human chorionic gonadotropin surveillance for partial hydatidiform moles.

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Lavie I, Rao GG, Castrillon DH, Miller DS, and Schorge JO

American journal of obstetrics and gynecology 192(5):1362-4, 2005 May - Who cited this? | PubMed ID: 15902109 | Fulltext

Complete hydatidiform mole retaining a chromosome 11 of maternal origin: molecular genetic analysis of a case.

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Fisher RA, Nucci MR, Thaker HM, Weremowicz S, Genest DR, and Castrillon DH

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 17(9):1155, 2004 Sep - Who cited this? | PubMed ID: 15314611 | Fulltext

Immunohistochemistry for the imprinted gene product IPL/PHLDA2 for facilitating the differential diagnosis of complete hydatidiform mole.

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Thaker HM, Berlin A, Tycko B, Goldstein DP, Berkowitz RS, Castrillon DH, and Genest DR

The Journal of reproductive medicine 49(8):630-6, 2004 Aug - Who cited this? | PubMed ID: 15457853 | Fulltext

The differential impact of p16(INK4a) or p19(ARF) deficiency on cell growth and tumorigenesis.

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Sharpless NE, Ramsey MR, Balasubramanian P, Castrillon DH, and Depinho RA

Oncogene 23(2):379, 2004 Jan 15 - Who cited this? | PubMed ID: 14724566 | Fulltext

Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a.

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Castrillon DH, Miao L, Kollipara R, Horner JW, and DePinho RA

Science (New York, N.Y.) 301(5630):215-8, 2003 Jul 11 - Who cited this? | PubMed ID: 12855809 | Fulltext

Biomarkers in diagnostic obstetric and gynecologic pathology: a review.

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Nucci MR, Castrillon DH, Bai H, Quade BJ, Ince TA, Genest DR, Lee KR, Mutter GL, and Crum CP

Advances in anatomic pathology 10(2):55-68, 2003 Mar - Who cited this? | PubMed ID: 12605088 | Fulltext

The maternally transcribed gene p57(KIP2) (CDNK1C) is abnormally expressed in both androgenetic and biparental complete hydatidiform moles.

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Fisher RA, Hodges MD, Rees HC, Sebire NJ, Seckl MJ, Newlands ES, Genest DR, and Castrillon DH

Human molecular genetics 11(26):3267, 2002 Dec 15 - Who cited this? | PubMed ID: 12471053 | Fulltext

Constitutive telomerase expression promotes mammary carcinomas in aging mice.

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Artandi SE, Alson S, Tietze MK, Sharpless NE, Ye S, Greenberg RA, Castrillon DH, Horner JW, Weiler SR, Carrasco RD, and DePinho RA

Proceedings of the National Academy of Sciences of the United States of America 99(12):8191-6, 2002 Jun 11 - Who cited this? | PubMed ID: 12034875 | Fulltext

p16(INK4a) and p53 deficiency cooperate in tumorigenesis.

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Sharpless NE, Alson S, Chan S, Silver DP, Castrillon DH, and DePinho RA

Cancer research 62(10):2761-5, 2002 May 15 - Who cited this? | PubMed ID: 12019151 | Fulltext

Ploidy and imprinting in hydatidiform moles. Complementary use of flow cytometry and immunohistochemistry of the imprinted gene product p57KIP2 to assist molar classification.

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Genest DR, Dorfman DM, and Castrillon DH

The Journal of reproductive medicine 47(5):342-6, 2002 May - Who cited this? | PubMed ID: 12063872 | Fulltext

Genetic analysis of Pten and Ink4a/Arf interactions in the suppression of tumorigenesis in mice.

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You MJ, Castrillon DH, Bastian BC, O'Hagan RC, Bosenberg MW, Parsons R, Chin L, and DePinho RA

Proceedings of the National Academy of Sciences of the United States of America 99(3):1455-60, 2002 Feb 5 - Who cited this? | PubMed ID: 11818530 | Fulltext

VASA is a specific marker for both normal and malignant human germ cells.

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Zeeman AM, Stoop H, Boter M, Gillis AJ, Castrillon DH, Oosterhuis JW, and Looijenga LH

Laboratory investigation; a journal of technical methods and pathology 82(2):159-66, 2002 Feb - Who cited this? | PubMed ID: 11850529 | Fulltext

Distinction between endometrial and endocervical adenocarcinoma: an immunohistochemical study.

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Castrillon DH, Lee KR, and Nucci MR

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 21(1):4-10, 2002 Jan - Who cited this? | PubMed ID: 11781516 | Fulltext

Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions.

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Sharpless NE, Ferguson DO, O'Hagan RC, Castrillon DH, Lee C, Farazi PA, Alson S, Fleming J, Morton CC, Frank K, Chin L, Alt FW, and Depinho RA

Molecular cell 8(6):1187, 2001 Dec - Who cited this? | PubMed ID: 11779495 | Fulltext

Pathologic findings in eight cases of ovarian serous borderline tumors, three with foci of serous carcinoma, that preceded death or morbidity from invasive carcinoma.

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Lee KR, Castrillon DH, and Nucci MR

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 20(4):329-34, 2001 Oct - Who cited this? | PubMed ID: 11603215 | Fulltext

Discrimination of complete hydatidiform mole from its mimics by immunohistochemistry of the paternally imprinted gene product p57KIP2.

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Castrillon DH, Sun D, Weremowicz S, Fisher RA, Crum CP, and Genest DR

The American journal of surgical pathology 25(10):1225-30, 2001 Oct - Who cited this? | PubMed ID: 11688455 | Fulltext

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis.

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Sharpless NE, Bardeesy N, Lee KH, Carrasco D, Castrillon DH, Aguirre AJ, Wu EA, Horner JW, and DePinho RA

Nature 413(6851):86-91, 2001 Sep 6 - Who cited this? | PubMed ID: 11544531 | Fulltext

Excessive tumor-elaborated VEGF and its neutralization define a lethal paraneoplastic syndrome.

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Wong AK, Alfert M, Castrillon DH, Shen Q, Holash J, Yancopoulos GD, and Chin L

Proceedings of the National Academy of Sciences of the United States of America 98(13):7481-6, 2001 Jun 19 - Who cited this? | PubMed ID: 11404464 | Fulltext

Multimodality therapy in early-stage neuroendocrine carcinoma of the uterine cervix.

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Boruta DM, Schorge JO, Duska LA, Crum CP, Castrillon DH, and Sheets EE

Gynecologic oncology 81(1):82-7, 2001 Apr - Who cited this? | PubMed ID: 11277655 | Fulltext

Modeling prostate cancer in the mouse.

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Castrillon DH and DePinho RA

Advances in cancer research 82:187-204, 2001 - Who cited this? | PubMed ID: 11447763 | Fulltext

The human VASA gene is specifically expressed in the germ cell lineage.

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Castrillon DH, Quade BJ, Wang TY, Quigley C, and Crum CP

Proceedings of the National Academy of Sciences of the United States of America 97(17):9585-90, 2000 Aug 15 - Who cited this? | PubMed ID: 10920202 | Fulltext

UbcD1, a Drosophila ubiquitin-conjugating enzyme required for proper telomere behavior.

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Cenci G, Rawson RB, Belloni G, Castrillon DH, Tudor M, Petrucci R, Goldberg ML, Wasserman SA, and Gatti M

Genes & development 11(7):863-75, 1997 Apr 1 - Who cited this? | PubMed ID: 9106658 | Fulltext

Control of male sexual behavior and sexual orientation in Drosophila by the fruitless gene.

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Ryner LC, Goodwin SF, Castrillon DH, Anand A, Villella A, Baker BS, Hall JC, Taylor BJ, and Wasserman SA

Cell 87(6):1079-89, 1996 Dec 13 - Who cited this? | PubMed ID: 8978612 | Fulltext

Diaphanous is required for cytokinesis in Drosophila and shares domains of similarity with the products of the limb deformity gene.

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Castrillon DH and Wasserman SA

Development (Cambridge, England) 120(12):3367-77, 1994 Dec - Who cited this? | PubMed ID: 7821209 | Fulltext

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