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Papers authored by Brunger AT

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Neuroligin-1 performs neurexin-dependent and neurexin-independent functions in synapse validation.

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Ko J, Zhang C, Arac D, Boucard AA, Brunger AT, and Südhof TC

The EMBO journal 28(20):3244-55, 2009 Oct 21 - Who cited this? | PubMed ID: 19730411 | Fulltext

Receptor and substrate interactions of clostridial neurotoxins.

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Brunger AT and Rummel A

Toxicon : official journal of the International Society on Toxinology 54(5):550-60, 2009 Oct - Who cited this? | PubMed ID: 19268493 | Fulltext

Polarizable atomic multipole X-ray refinement: application to peptide crystals.

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Schnieders MJ, Fenn TD, Pande VS, and Brunger AT

Acta crystallographica. Section D, Biological crystallography 65(Pt 9):952-65, 2009 Sep - Who cited this? | PubMed ID: 19690373 | Fulltext

Mechanistic insights into active site-associated polyubiquitination by the ubiquitin-conjugating enzyme Ube2g2.

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Li W, Tu D, Li L, Wollert T, Ghirlando R, Brunger AT, and Ye Y

Proceedings of the National Academy of Sciences of the United States of America 106(10):3722-7, 2009 Mar 10 - Who cited this? | PubMed ID: 19223579 | Fulltext

X-ray structure determination at low resolution.

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Brunger AT, Delabarre B, Davies JM, and Weis WI

Acta crystallographica. Section D, Biological crystallography 65(Pt 2):128-33, 2009 Feb - Who cited this? | PubMed ID: 19171967 | Fulltext

Single-Molecule Studies of the Neuronal SNARE Fusion Machinery.

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Brunger AT, Weninger K, Bowen M, and Chu S

Annual review of biochemistry 78:903-28, 2009 - Who cited this? | PubMed ID: 19489736 | Fulltext

A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has a Very Different Conformation than SNAP-25 Substrate.

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Zuniga JE, Schmidt JJ, Fenn T, Burnett JC, Araç D, Gussio R, Stafford RG, Badie SS, Bavari S, and Brunger AT

Structure (London, England : 1993) 16(10):1588-97, 2008 Oct - Who cited this? | PubMed ID: 18940613 | Fulltext

Highly specific interactions between botulinum neurotoxins and synaptic vesicle proteins.

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Brunger AT, Jin R, and Breidenbach MA

Cellular and molecular life sciences : CMLS 65(15):2296-306, 2008 Aug - Who cited this? | PubMed ID: 18425411 | Fulltext

Improved Structures of Full-Length p97, an AAA ATPase: Implications for Mechanisms of Nucleotide-Dependent Conformational Change.

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Davies JM, Brunger AT, and Weis WI

Structure (London, England : 1993) 16(5):715-26, 2008 May - Who cited this? | PubMed ID: 18462676 | Fulltext

Accessory Proteins Stabilize the Acceptor Complex for Synaptobrevin, the 1:1 Syntaxin/SNAP-25 Complex.

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Weninger K, Bowen ME, Choi UB, Chu S, and Brunger AT

Structure (London, England : 1993) 16(2):308-20, 2008 Feb - Who cited this? | PubMed ID: 18275821 | Fulltext

Rab and Arl GTPase family members cooperate in the localization of the golgin GCC185.

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Burguete AS, Fenn TD, Brunger AT, and Pfeffer SR

Cell 132(2):286, 2008 Jan 25 - Who cited this? | PubMed ID: 18243103 | Fulltext

The Structure of the Yeast Plasma Membrane SNARE Complex Reveals Destabilizing Water-filled Cavities.

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Strop P, Kaiser SE, Vrljic M, and Brunger AT

The Journal of biological chemistry 283(2):1113-9, 2008 Jan 11 - Who cited this? | PubMed ID: 17956869 | Fulltext

Structures of neuroligin-1 and the neuroligin-1/neurexin-1 beta complex reveal specific protein-protein and protein-Ca2+ interactions.

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Araç D, Boucard AA, Ozkan E, Strop P, Newell E, Südhof TC, and Brunger AT

Neuron 56(6):992, 2007 Dec 20 - Who cited this? | PubMed ID: 18093522 | Fulltext

Transglutaminase 2 undergoes a large conformational change upon activation.

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Pinkas DM, Strop P, Brunger AT, and Khosla C

PLoS biology 5(12), 2007 Dec - Who cited this? | PubMed ID: 18092889 | Fulltext

Combining efficient conformational sampling with a deformable elastic network model facilitates structure refinement at low resolution.

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Schröder GF, Brunger AT, and Levitt M

Structure (London, England : 1993) 15(12):1630-41, 2007 Dec - Who cited this? | PubMed ID: 18073112 | Fulltext

Inaugural Article: Structure and function of the yeast U-box-containing ubiquitin ligase Ufd2p.

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Tu D, Li W, Ye Y, and Brunger AT

Proceedings of the National Academy of Sciences of the United States of America 104(40):15599, 2007 Oct 2 - Who cited this? | PubMed ID: 17890322 | Fulltext

Structural and biochemical studies of botulinum neurotoxin serotype C1 light chain protease: implications for dual substrate specificity.

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Jin R, Sikorra S, Stegmann CM, Pich A, Binz T, and Brunger AT

Biochemistry 46(37):10685-93, 2007 Sep 18 - Who cited this? | PubMed ID: 17718519 | Fulltext

Botulinum neurotoxin heavy chain belt as an intramolecular chaperone for the light chain.

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Brunger AT, Breidenbach MA, Jin R, Fischer A, Santos JS, and Montal M

PLoS pathogens 3(9):1191, 2007 Sep 7 - Who cited this? | PubMed ID: 17907800 | Fulltext

Crystallography: crystallographic evidence for deviating C3b structure.

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Janssen BJ, Read RJ, Brünger AT, and Gros P

Nature 448(7154), 2007 Aug 9 - Who cited this? | PubMed ID: 17687277 | Fulltext

Crystal structure of a hyperactive Escherichia coli glycerol kinase mutant Gly230 --> Asp obtained using microfluidic crystallization devices.

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Anderson MJ, DeLaBarre B, Raghunathan A, Palsson BO, Brunger AT, and Quake SR

Biochemistry 46(19):5722, 2007 May 15 - Who cited this? | PubMed ID: 17441732 | Fulltext

A ubiquitin ligase transfers preformed polyubiquitin chains from a conjugating enzyme to a substrate.

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Li W, Tu D, Brunger AT, and Ye Y

Nature 446(7133):333-7, 2007 Mar 15 - Who cited this? | PubMed ID: 17310145 | Fulltext

Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons.

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Burnett JC, Ruthel G, Stegmann CM, Panchal RG, Nguyen TL, Hermone AR, Stafford RG, Lane DJ, Kenny TA, McGrath CF, Wipf P, Stahl AM, Schmidt JJ, Gussio R, Brunger AT, and Bavari S

The Journal of biological chemistry 282(7):5004-14, 2007 Feb 16 - Who cited this? | PubMed ID: 17092934 | Fulltext

Ab initio molecular-replacement phasing for symmetric helical membrane proteins.

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Strop P, Brzustowicz MR, and Brunger AT

Acta crystallographica. Section D, Biological crystallography 63(Pt 2):188-96, 2007 Feb - Who cited this? | PubMed ID: 17242512 | Fulltext

Version 1.2 of the Crystallography and NMR system.

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Brunger AT

Nature protocols 2(11):2728-33, 2007 - Who cited this? | PubMed ID: 18007608 | Fulltext

Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity.

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Jin R, Rummel A, Binz T, and Brunger AT

Nature 444(7122):1092-5, 2006 Dec 21 - Who cited this? | PubMed ID: 17167421 | Fulltext

Structural and functional comparisons of nucleotide pyrophosphatase/phosphodiesterase and alkaline phosphatase: implications for mechanism and evolution.

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Zalatan JG, Fenn TD, Brunger AT, and Herschlag D

Biochemistry 45(32):9788, 2006 Aug 15 - Who cited this? | PubMed ID: 16893180 | Fulltext

Ensemble molecular dynamics yields submillisecond kinetics and intermediates of membrane fusion.

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Kasson PM, Kelley NW, Singhal N, Vrljic M, Brunger AT, and Pande VS

Proceedings of the National Academy of Sciences of the United States of America 103(32):11916, 2006 Aug 8 - Who cited this? | PubMed ID: 16880392 | Fulltext

Considerations for the refinement of low-resolution crystal structures.

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DeLaBarre B and Brunger AT

Acta crystallographica. Section D, Biological crystallography 62(Pt 8):923-32, 2006 Aug - Who cited this? | PubMed ID: 16855310 | Fulltext

Conformation of the synaptobrevin transmembrane domain.

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Bowen M and Brunger AT

Proceedings of the National Academy of Sciences of the United States of America 103(22):8378-83, 2006 May 30 - Who cited this? | PubMed ID: 16709671 | Fulltext

Central pore residues mediate the p97/VCP activity required for ERAD.

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DeLaBarre B, Christianson JC, Kopito RR, and Brunger AT

Molecular cell 22(4):451, 2006 May 19 - Who cited this? | PubMed ID: 16713576 | Fulltext

Neuronal SNAREs do not trigger fusion between synthetic membranes but do promote PEG-mediated membrane fusion.

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Dennison SM, Bowen ME, Brunger AT, and Lentz BR

Biophysical journal 90(5):1661-75, 2006 Mar 1 - Who cited this? | PubMed ID: 16339880 | Fulltext

A hybrid machine-learning approach for segmentation of protein localization data.

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Kasson PM, Huppa JB, Davis MM, and Brunger AT

Bioinformatics (Oxford, England) 21(19):3778, 2005 Oct 1 - Who cited this? | PubMed ID: 16091410 | Fulltext

Automated crystallographic ligand building using the medial axis transform of an electron-density isosurface.

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Aishima J, Russel DS, Guibas LJ, Adams PD, and Brunger AT

Acta crystallographica. Section D, Biological crystallography 61(Pt 10):1354-63, 2005 Oct - Who cited this? | PubMed ID: 16204887 | Fulltext

Refractive index-based determination of detergent concentration and its application to the study of membrane proteins.

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Strop P and Brunger AT

Protein science : a publication of the Protein Society 14(8):2207-11, 2005 Aug - Who cited this? | PubMed ID: 16046633 | Fulltext

New insights into clostridial neurotoxin-SNARE interactions.

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Breidenbach MA and Brunger AT

Trends in molecular medicine 11(8):377-81, 2005 Aug - Who cited this? | PubMed ID: 16006188 | Fulltext

Structural basis of FFAT motif-mediated ER targeting.

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Kaiser SE, Brickner JH, Reilein AR, Fenn TD, Walter P, and Brunger AT

Structure (London, England : 1993) 13(7):1035, 2005 Jul - Who cited this? | PubMed ID: 16004875 | Fulltext

Single-molecule studies of synaptotagmin and complexin binding to the SNARE complex.

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Bowen ME, Weninger K, Ernst J, Chu S, and Brunger AT

Biophysical journal 89(1):690-702, 2005 Jul - Who cited this? | PubMed ID: 15821166 | Fulltext

Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase.

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Jin R, Junutula JR, Matern HT, Ervin KE, Scheller RH, and Brunger AT

The EMBO journal 24(12):2064-74, 2005 Jun 15 - Who cited this? | PubMed ID: 15920473 | Fulltext

2.3 A crystal structure of tetanus neurotoxin light chain.

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Breidenbach MA and Brunger AT

Biochemistry 44(20):7450-7, 2005 May 24 - Who cited this? | PubMed ID: 15895988 | Fulltext

Nucleotide dependent motion and mechanism of action of p97/VCP.

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DeLaBarre B and Brunger AT

Journal of molecular biology 347(2):437-52, 2005 Mar 25 - Who cited this? | PubMed ID: 15740751 | Fulltext

Low-resolution crystallography is coming of age.

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Brunger AT

Structure (London, England : 1993) 13(2):171, 2005 Feb - Who cited this? | PubMed ID: 15698560 | Fulltext

Structure and function of SNARE and SNARE-interacting proteins.

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Brunger AT

Quarterly reviews of biophysics 38(1):1-47, 2005 Feb - Who cited this? | PubMed ID: 16336742 | Fulltext

Quantitative imaging of lymphocyte membrane protein reorganization and signaling.

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Kasson PM, Huppa JB, Krogsgaard M, Davis MM, and Brunger AT

Biophysical journal 88(1):579-89, 2005 Jan - Who cited this? | PubMed ID: 15501943 | Fulltext

Deformable modeling for improved calculation of molecular velocities from single-particle tracking.

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Kasson PM, Davis MM, and Brunger AT

Proceedings / IEEE Computational Systems Bioinformatics Conference, CSB. IEEE Computational Systems Bioinformatics Conference:208-11, 2005 - Who cited this? | PubMed ID: 16447978 | Fulltext

Substrate recognition strategy for botulinum neurotoxin serotype A.

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Breidenbach MA and Brunger AT

Nature 432(7019):925, 2004 Dec 16 - Who cited this? | PubMed ID: 15592454 | Fulltext

Single molecule observation of liposome-bilayer fusion thermally induced by soluble N-ethyl maleimide sensitive-factor attachment protein receptors (SNAREs).

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Bowen ME, Weninger K, Brunger AT, and Chu S

Biophysical journal 87(5):3569-84, 2004 Nov - Who cited this? | PubMed ID: 15347585 | Fulltext

Structure of a human A-type potassium channel interacting protein DPPX, a member of the dipeptidyl aminopeptidase family.

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Strop P, Bankovich AJ, Hansen KC, Garcia KC, and Brunger AT

Journal of molecular biology 343(4):1055, 2004 Oct 29 - Who cited this? | PubMed ID: 15476821 | Fulltext

Exploring the structural dynamics of the E.coli chaperonin GroEL using translation-libration-screw crystallographic refinement of intermediate states.

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Chaudhry C, Horwich AL, Brunger AT, and Adams PD

Journal of molecular biology 342(1):229-45, 2004 Sep 3 - Who cited this? | PubMed ID: 15313620 | Fulltext

Single-molecule studies of SNARE complex assembly reveal parallel and antiparallel configurations.

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Weninger K, Bowen ME, Chu S, and Brunger AT

Proceedings of the National Academy of Sciences of the United States of America 100(25):14800-5, 2003 Dec 9 - Who cited this? | PubMed ID: 14657376 | Fulltext

NSF and p97/VCP: similar at first, different at last.

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Brunger AT and DeLaBarre B

FEBS letters 555(1):126-33, 2003 Nov 27 - Who cited this? | PubMed ID: 14630332 | Fulltext

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