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Papers authored by Breyer MD

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Effects of global or targeted deletion of the EP4 receptor on the response of osteoblasts to prostaglandin in vitro and on bone histomorphometry in aged mice.

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Gao Q, Zhan P, Alander CB, Kream BE, Hao C, Breyer MD, Pilbeam CC, and Raisz LG

Bone 45(1):98-103, 2009 Jul - Who cited this? | PubMed ID: 19344793 | Fulltext

Reduction of renal superoxide dismutase in progressive diabetic nephropathy.

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Fujita H, Fujishima H, Chida S, Takahashi K, Qi Z, Kanetsuna Y, Breyer MD, Harris RC, Yamada Y, and Takahashi T

Journal of the American Society of Nephrology : JASN 20(6):1303-13, 2009 Jun - Who cited this? | PubMed ID: 19470681 | Fulltext

Measurement of glomerular filtration rate in conscious mice.

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Qi Z and Breyer MD

Methods in molecular biology (Clifton, N.J.) 466:1-12, 2009 - Who cited this? | PubMed ID: 19148601 | Fulltext

Macrophage EP4 Deficiency Increases Apoptosis and Suppresses Early Atherosclerosis.

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Babaev VR, Chew JD, Ding L, Davis S, Breyer MD, Breyer RM, Oates JA, Fazio S, and Linton MF

Cell metabolism 8(6):492-501, 2008 Dec - Who cited this? | PubMed ID: 19041765 | Fulltext

Single amino Acid substitution in aquaporin 11 causes renal failure.

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Tchekneva EE, Khuchua Z, Davis LS, Kadkina V, Dunn SR, Bachman S, Ishibashi K, Rinchik EM, Harris RC, Dikov MM, and Breyer MD

Journal of the American Society of Nephrology : JASN 19(10):1955-64, 2008 Oct - Who cited this? | PubMed ID: 18701606 | Fulltext

Stacking the deck for drug discovery in diabetic nephropathy: in search of an animal model.

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Breyer MD

Journal of the American Society of Nephrology : JASN 19(9):1623-4, 2008 Sep - Who cited this? | PubMed ID: 18684892 | Fulltext

Markers of Glycemic Control in the Mouse: Comparisons of Six-hour and Overnight Fasted Blood Glucoses to HbA1c.

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Han BG, Hao CM, Tchekneva EE, Wang YY, Lee CA, Ebrahim B, Harris RC, Kern TS, Wasserman DH, Breyer MD, and Qi Z

American journal of physiology. Endocrinology and metabolism, 2008 Jul 29 - Who cited this? | PubMed ID: 18664598 | Fulltext

Expression profiling of hepatic genes associated with lipid metabolism in nephrotic rats.

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Zhou Y, Zhang X, Chen L, Wu J, Dang H, Wei MF, Fan Y, Zhang Y, Zhu Y, Wang N, Breyer MD, and Guan Y

American journal of physiology. Renal physiology, 2008 Jul 9 - Who cited this? | PubMed ID: 18614621 | Fulltext

Apoptosis of the Thick Ascending Limb Results in Acute Kidney Injury.

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Srichai MB, Hao C, Davis L, Golovin A, Zhao M, Moeckel G, Dunn S, Bulus N, Harris RC, Zent R, and Breyer MD

Journal of the American Society of Nephrology : JASN, 2008 May 21 - Who cited this? | PubMed ID: 18495962 | Fulltext

Mouse EP3 {alpha}, {beta}, and {gamma} Receptor Variants Reduce Tumor Cell Proliferation and Tumorigenesis in Vivo.

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Macias-Perez IM, Zent R, Carmosino M, Breyer MD, Breyer RM, and Pozzi A

The Journal of biological chemistry 283(18):12538-45, 2008 May 2 - Who cited this? | PubMed ID: 18230618 | Fulltext

Physiological regulation of prostaglandins in the kidney.

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Hao CM and Breyer MD

Annual review of physiology 70:357, 2008 - Who cited this? | PubMed ID: 17988207 | Fulltext

Insight into the genetics of diabetic nephropathy through the study of mice.

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Breyer MD, Qi Z, Tchekneva EE, and Harris RC

Current opinion in nephrology and hypertension 17(1):82-6, 2008 Jan - Who cited this? | PubMed ID: 18090675 | Fulltext

Examining diabetic nephropathy through the lens of mouse genetics.

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Breyer MD, Tchekneva E, Qi Z, Takahashi T, Fogo AB, and Harris RC

Current diabetes reports 7(6):459-66, 2007 Dec - Who cited this? | PubMed ID: 18255011 | Fulltext

Effect of selective cyclooxygenase-2 (COX-2) inhibitor treatment on glucose-stimulated insulin secretion in C57BL/6 mice.

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Fujita H, Kakei M, Fujishima H, Morii T, Yamada Y, Qi Z, and Breyer MD

Biochemical and biophysical research communications 363(1):37-43, 2007 Nov 9 - Who cited this? | PubMed ID: 17825788 | Fulltext

Antihypertensive effects of selective prostaglandin E2 receptor subtype 1 targeting.

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Guan Y, Zhang Y, Wu J, Qi Z, Yang G, Dou D, Gao Y, Chen L, Zhang X, Davis LS, Wei M, Fan X, Carmosino M, Hao C, Imig JD, Breyer RM,

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The Journal of clinical investigation 117(9):2496, 2007 Sep - Who cited this? | PubMed ID: 17710229 | Fulltext

Peroxisome proliferator activated receptor alpha/gamma dual agonist tesaglitazar attenuates diabetic nephropathy in db/db mice.

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Cha DR, Zhang X, Zhang Y, Wu J, Su D, Han JY, Fang X, Yu B, Breyer MD, and Guan Y

Diabetes 56(8):2036-45, 2007 Aug - Who cited this? | PubMed ID: 17536062 | Fulltext

Prostaglandin E2-EP4 receptor promotes endothelial cell migration via ERK activation and angiogenesis in vivo.

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Rao R, Redha R, Macias-Perez I, Su Y, Hao C, Zent R, Breyer MD, and Pozzi A

The Journal of biological chemistry 282(23):16959-68, 2007 Jun 8 - Who cited this? | PubMed ID: 17401137 | Fulltext

Physiologic and pathophysiologic roles of lipid mediators in the kidney.

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Hao CM and Breyer MD

Kidney international 71(11):1105-15, 2007 Jun - Who cited this? | PubMed ID: 17361113 | Fulltext

Deficiency of endothelial nitric-oxide synthase confers susceptibility to diabetic nephropathy in nephropathy-resistant inbred mice.

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Kanetsuna Y, Takahashi K, Nagata M, Gannon MA, Breyer MD, Harris RC, and Takahashi T

The American journal of pathology 170(5):1473-84, 2007 May - Who cited this? | PubMed ID: 17456755 | Fulltext

Expression of nestin in the podocytes of normal and diseased human kidneys.

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Su W, Chen J, Yang H, You L, Xu L, Wang X, Li R, Gao L, Gu Y, Lin S, Xu H, Breyer MD, and Hao CM

American journal of physiology. Regulatory, integrative and comparative physiology 292(5):R1761-7, 2007 May - Who cited this? | PubMed ID: 17255215 | Fulltext

Roles of lipid mediators in kidney injury.

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Hao CM and Breyer MD

Seminars in nephrology 27(3):338-51, 2007 May - Who cited this? | PubMed ID: 17533010 | Fulltext

Long-term treatment of glucagon-like peptide-1 analog exendin-4 ameliorates diabetic nephropathy through improving metabolic anomalies in db/db mice.

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Park CW, Kim HW, Ko SH, Lim JH, Ryu GR, Chung HW, Han SW, Shin SJ, Bang BK, Breyer MD, and Chang YS

Journal of the American Society of Nephrology : JASN 18(4):1227-38, 2007 Apr - Who cited this? | PubMed ID: 17360951 | Fulltext

Diabetic nephropathy: introduction.

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Breyer MD

Seminars in nephrology 27(2):129, 2007 Mar - Who cited this? | PubMed ID: 17418681 | Fulltext

Genetics of diabetic nephropathy: lessons from mice.

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Breyer MD, Tchekneva E, Qi Z, Takahashi T, Fogo AB, Zhao HJ, and Harris RC

Seminars in nephrology 27(2):237-47, 2007 Mar - Who cited this? | PubMed ID: 17418691 | Fulltext

Glycogen synthase kinase 3 inhibition improves insulin-stimulated glucose metabolism but not hypertension in high-fat-fed C57BL/6J mice.

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Rao R, Hao CM, Redha R, Wasserman DH, McGuinness OP, and Breyer MD

Diabetologia 50(2):452-60, 2007 Feb - Who cited this? | PubMed ID: 17151860 | Fulltext

Overexpression of cyclooxygenase-2 predisposes to podocyte injury.

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Cheng H, Wang S, Jo YI, Hao CM, Zhang M, Fan X, Kennedy C, Breyer MD, Moeckel GW, and Harris RC

Journal of the American Society of Nephrology : JASN 18(2):551-9, 2007 Feb - Who cited this? | PubMed ID: 17202413 | Fulltext

Urine concentrating defect in prostaglandin EP1-deficient mice.

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Kennedy CR, Xiong H, Rahal S, Vanderluit J, Slack RS, Zhang Y, Guan Y, Breyer MD, and Hébert RL

American journal of physiology. Renal physiology 292(2):F868-75, 2007 Feb - Who cited this? | PubMed ID: 16885154 | Fulltext

A sensitized screen of N-ethyl-N-nitrosourea-mutagenized mice identifies dominant mutants predisposed to diabetic nephropathy.

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Tchekneva EE, Rinchik EM, Polosukhina D, Davis LS, Kadkina V, Mohamed Y, Dunn SR, Sharma K, Qi Z, Fogo AB, and Breyer MD

Journal of the American Society of Nephrology : JASN 18(1):103, 2007 Jan - Who cited this? | PubMed ID: 17151334 | Fulltext

Axial heterogeneity of vasopressin-receptor subtypes along the human and mouse collecting duct.

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Carmosino M, Brooks HL, Cai Q, Davis LS, Opalenik S, Hao C, and Breyer MD

American journal of physiology. Renal physiology 292(1):F351-60, 2007 Jan - Who cited this? | PubMed ID: 16835408 | Fulltext

Peroxisome proliferator-activated receptor-alpha deficiency protects aged mice from insulin resistance induced by high-fat diet.

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Cha DR, Han JY, Su DM, Zhang Y, Fan X, Breyer MD, and Guan Y

American journal of nephrology 27(5):479-82, 2007 - Who cited this? | PubMed ID: 17652964 | Fulltext

Characterization of diabetic nephropathy in a transgenic model of hypoinsulinemic diabetes.

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Kanetsuna Y, Hirano K, Nagata M, Gannon MA, Takahashi K, Harris RC, Breyer MD, and Takahashi T

American journal of physiology. Renal physiology 291(6):F1315-22, 2006 Dec - Who cited this? | PubMed ID: 16705146 | Fulltext

Expression of mouse membrane-associated prostaglandin E2 synthase-2 (mPGES-2) along the urogenital tract.

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Yang G, Chen L, Zhang Y, Zhang X, Wu J, Li S, Wei M, Zhang Z, Breyer MD, and Guan Y

Biochimica et biophysica acta 1761(12):1459-68, 2006 Dec - Who cited this? | PubMed ID: 17064959 | Fulltext

Endothelial nitric oxide synthase deficiency produces accelerated nephropathy in diabetic mice.

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Zhao HJ, Wang S, Cheng H, Zhang MZ, Takahashi T, Fogo AB, Breyer MD, and Harris RC

Journal of the American Society of Nephrology : JASN 17(10):2664-9, 2006 Oct - Who cited this? | PubMed ID: 16971655 | Fulltext

Differentiation of cyclooxygenase 1- and 2-derived prostanoids in mouse kidney and aorta.

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Qi Z, Cai H, Morrow JD, and Breyer MD

Hypertension 48(2):323-8, 2006 Aug - Who cited this? | PubMed ID: 16801485 | Fulltext

Glomerular injury is exacerbated in diabetic integrin alpha1-null mice.

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Zent R, Yan X, Su Y, Hudson BG, Borza DB, Moeckel GW, Qi Z, Sado Y, Breyer MD, Voziyan P, and Pozzi A

Kidney international 70(3):460-70, 2006 Aug - Who cited this? | PubMed ID: 16775606 | Fulltext

Cardiovascular effects of selective COX-2 inhibition: is there a class effect? The International COX-2 Study Group.

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Crofford LJ, Breyer MD, Strand CV, Rushitzka F, Brune K, Farkouh ME, and Simon LS

The Journal of rheumatology 33(7):1403-8, 2006 Jul - Who cited this? | PubMed ID: 16724374 | Fulltext

Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel.

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Nakagawa K, Holla VR, Wei Y, Wang WH, Gatica A, Wei S, Mei S, Miller CM, Cha DR, Price E, Zent R, Pozzi A, Breyer MD, Guan Y, Falck JR, Waterman MR,

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The Journal of clinical investigation 116(6):1696-702, 2006 Jun - Who cited this? | PubMed ID: 16691295 | Fulltext

Differential expression of the intermediate filament protein nestin during renal development and its localization in adult podocytes.

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Chen J, Boyle S, Zhao M, Su W, Takahashi K, Davis L, Decaestecker M, Takahashi T, Breyer MD, and Hao CM

Journal of the American Society of Nephrology : JASN 17(5):1283, 2006 May - Who cited this? | PubMed ID: 16571784 | Fulltext

Liver X receptor agonist TO-901317 upregulates SCD1 expression in renal proximal straight tubule.

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Zhang Y, Zhang X, Chen L, Wu J, Su D, Lu WJ, Hwang MT, Yang G, Li S, Wei M, Davis L, Breyer MD, and Guan Y

American journal of physiology. Renal physiology 290(5):F1065-73, 2006 May - Who cited this? | PubMed ID: 16368743 | Fulltext

Diabetic nephropathy: leveraging mouse genetics.

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Breyer MD, Qi Z, and Tchekneva E

Current opinion in nephrology and hypertension 15(3):227-32, 2006 May - Who cited this? | PubMed ID: 16609287 | Fulltext

Accelerated diabetic nephropathy in mice lacking the peroxisome proliferator-activated receptor alpha.

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Park CW, Kim HW, Ko SH, Chung HW, Lim SW, Yang CW, Chang YS, Sugawara A, Guan Y, and Breyer MD

Diabetes 55(4):885-93, 2006 Apr - Who cited this? | PubMed ID: 16567507 | Fulltext

Update on cyclooxygenase-2 inhibitors.

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Harris RC and Breyer MD

Clinical journal of the American Society of Nephrology : CJASN 1(2):236-45, 2006 Mar - Who cited this? | PubMed ID: 17699212 | Fulltext

Cyclooxygenase-1 deficiency in bone marrow cells increases early atherosclerosis in apolipoprotein E- and low-density lipoprotein receptor-null mice.

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Babaev VR, Ding L, Reese J, Morrow JD, Breyer MD, Dey SK, Fazio S, and Linton MF

Circulation 113(1):108-17, 2006 Jan 3 - Who cited this? | PubMed ID: 16380543 | Fulltext

Increased severity of renal impairment in nephritic mice lacking the EP1 receptor.

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Rahal S, McVeigh LI, Zhang Y, Guan Y, Breyer MD, and Kennedy CR

Canadian journal of physiology and pharmacology 84(8-9):877-85, 2006 - Who cited this? | PubMed ID: 17111032 | Fulltext

Effect of deletion of the prostaglandin EP4 receptor on stimulation of calcium release from cultured mouse calvariae: impaired responsiveness in heterozygotes.

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Zhan P, Alander C, Kaneko H, Pilbeam CC, Guan Y, Zhang Y, Breyer MD, and Raisz LG

Prostaglandins & other lipid mediators 78(1-4):19-26, 2005 Dec - Who cited this? | PubMed ID: 16303601 | Fulltext

Characterization of a rabbit kidney prostaglandin F(2{alpha}) receptor exhibiting G(i)-restricted signaling that inhibits water absorption in the collecting duct.

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Hébert RL, Carmosino M, Saito O, Yang G, Jackson CA, Qi Z, Breyer RM, Natarajan C, Hata AN, Zhang Y, Guan Y, and Breyer MD

The Journal of biological chemistry 280(41):35028-37, 2005 Oct 14 - Who cited this? | PubMed ID: 16096282 | Fulltext

Diabetic nephropathy: big and bad.

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Qi Z and Breyer MD

Kidney international 68(4):1896-7, 2005 Oct - Who cited this? | PubMed ID: 16164670 | Fulltext

Getting to the heart of COX-2 inhibition.

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Breyer MD

Cell metabolism 2(3):149, 2005 Sep - Who cited this? | PubMed ID: 16154096 | Fulltext

Characterization of susceptibility of inbred mouse strains to diabetic nephropathy.

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Qi Z, Fujita H, Jin J, Davis LS, Wang Y, Fogo AB, and Breyer MD

Diabetes 54(9):2628-37, 2005 Sep - Who cited this? | PubMed ID: 16123351 | Fulltext

Bradykinin B2 type receptor activation regulates fluid and electrolyte transport in the rabbit kidney.

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Hébert RL, Regoli D, Xiong H, Breyer MD, and Plante GE

Peptides 26(8):1308-16, 2005 Aug - Who cited this? | PubMed ID: 16042972 | Fulltext

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