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Papers authored by Brandt JT

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Prasugrel pharmacokinetics and pharmacodynamics in subjects with moderate renal impairment and end-stage renal disease.

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Small DS, Wrishko RE, Ernest CS, Ni L, Winters KJ, Farid NA, Li YG, Brandt JT, Salazar DE, Borel AG, Kles KA, and Payne CD

Journal of clinical pharmacy and therapeutics 34(5):585-94, 2009 Oct - Who cited this? | PubMed ID: 19744014 | Fulltext

Effect of rifampin on the pharmacokinetics and pharmacodynamics of prasugrel in healthy male subjects.

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Farid NA, Jakubowski JA, Payne CD, Li YG, Jin Y, Ernest II CS, Winters KJ, Brandt JT, Salazar DE, and Small DS

Current medical research and opinion 25(8):1821-9, 2009 Aug - Who cited this? | PubMed ID: 19530977 | Fulltext

Inhibition of platelet aggregation with prasugrel and clopidogrel: an integrated analysis in 846 subjects.

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Li YG, Ni L, Brandt JT, Small DS, Payne CD, Ernest CS, Rohatagi S, Farid NA, Jakubowski JA, and Winters KJ

Platelets 20(5):316-27, 2009 Aug - Who cited this? | PubMed ID: 19637095 | Fulltext

Genetic variation of CYP2C19 affects both pharmacokinetic and pharmacodynamic responses to clopidogrel but not prasugrel in aspirin-treated patients with coronary artery disease.

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Varenhorst C, James S, Erlinge D, Brandt JT, Braun OO, Man M, Siegbahn A, Walker J, Wallentin L, Winters KJ, and Close SL

European heart journal 30(14):1744-52, 2009 Jul - Who cited this? | PubMed ID: 19429918 | Fulltext

Cytochrome p450 genetic polymorphisms and the response to prasugrel: relationship to pharmacokinetic, pharmacodynamic, and clinical outcomes.

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Mega JL, Close SL, Wiviott SD, Shen L, Hockett RD, Brandt JT, Walker JR, Antman EM, Macias WL, Braunwald E, and Sabatine MS

Circulation 119(19):2553-60, 2009 May 19 - Who cited this? | PubMed ID: 19414633 | Fulltext

Assessment of P2Y(12) inhibition with the point-of-care device VerifyNow P2Y12 in patients treated with prasugrel or clopidogrel coadministered with aspirin.

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Varenhorst C, James S, Erlinge D, Braun OO, Brandt JT, Winters KJ, Jakubowski JA, Olofsson S, Wallentin L, and Siegbahn A

American heart journal 157(3):562.e1-9, 2009 Mar - Who cited this? | PubMed ID: 19249429 | Fulltext

Cytochrome p-450 polymorphisms and response to clopidogrel.

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Mega JL, Close SL, Wiviott SD, Shen L, Hockett RD, Brandt JT, Walker JR, Antman EM, Macias W, Braunwald E, and Sabatine MS

The New England journal of medicine 360(4):354-62, 2009 Jan 22 - Who cited this? | PubMed ID: 19106084 | Fulltext

Patients with poor responsiveness to thienopyridine treatment or with diabetes have lower levels of circulating active metabolite, but their platelets respond normally to active metabolite added ex vivo.

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Erlinge D, Varenhorst C, Braun OO, James S, Winters KJ, Jakubowski JA, Brandt JT, Sugidachi A, Siegbahn A, and Wallentin L

Journal of the American College of Cardiology 52(24):1968-77, 2008 Dec 9 - Who cited this? | PubMed ID: 19055987 | Fulltext

Effect of atorvastatin on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel in healthy subjects.

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Farid NA, Small DS, Payne CD, Jakubowski JA, Brandt JT, Li YG, Ernest CS, Salazar DE, Konkoy CS, and Winters KJ

Pharmacotherapy 28(12):1483-94, 2008 Dec - Who cited this? | PubMed ID: 19025429 | Fulltext

Greater reduction of platelet activation markers and platelet-monocyte aggregates by prasugrel compared to clopidogrel in stable coronary artery disease.

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Braun OO, Johnell M, Varenhorst C, James S, Brandt JT, Jakubowski JA, Winters KJ, Wallentin L, Erlinge D, and Siegbahn A

Thrombosis and haemostasis 100(4):626-33, 2008 Oct - Who cited this? | PubMed ID: 18841285 | Fulltext

Switching directly to prasugrel from clopidogrel results in greater inhibition of platelet aggregation in aspirin-treated subjects.

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Payne CD, Li YG, Brandt JT, Jakubowski JA, Small DS, Farid NA, Salazar DE, and Winters KJ

Platelets 19(4):275-81, 2008 Jun - Who cited this? | PubMed ID: 18569863 | Fulltext

Effects of the proton pump inhibitor lansoprazole on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel.

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Small DS, Farid NA, Payne CD, Weerakkody GJ, Li YG, Brandt JT, Salazar DE, and Winters KJ

Journal of clinical pharmacology 48(4):475-84, 2008 Apr - Who cited this? | PubMed ID: 18303127 | Fulltext

The use of the VerifyNow P2Y12 point-of-care device to monitor platelet function across a range of P2Y(12) inhibition levels following prasugrel and clopidogrel administration.

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Jakubowski JA, Payne CD, Li YG, Brandt JT, Small DS, Farid NA, Salazar DE, and Winters KJ

Thrombosis and haemostasis 99(2):409-15, 2008 Feb - Who cited this? | PubMed ID: 18278193 | Fulltext

A comparison of the antiplatelet effects of prasugrel and high-dose clopidogrel as assessed by VASP-phosphorylation and light transmission aggregometry.

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Jakubowski JA, Payne CD, Li YG, Farid NA, Brandt JT, Small DS, Salazar DE, and Winters KJ

Thrombosis and haemostasis 99(1):215-22, 2008 Jan - Who cited this? | PubMed ID: 18217157 | Fulltext

Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel.

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Brandt JT, Close SL, Iturria SJ, Payne CD, Farid NA, Ernest CS, Lachno DR, Salazar D, and Winters KJ

Journal of thrombosis and haemostasis : JTH 5(12):2429-36, 2007 Dec - Who cited this? | PubMed ID: 17900275 | Fulltext

Laboratory reporting of the international normalized ratio: progress and problems.

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Olson JD, Brandt JT, Chandler WL, Van Cott EM, Cunningham MT, Hayes TE, Kottke-Marchant KK, Makar RS, Uy AB, and Wang EC

Archives of pathology & laboratory medicine 131(11):1641-7, 2007 Nov - Who cited this? | PubMed ID: 17979481 | Fulltext

Increased active metabolite formation explains the greater platelet inhibition with prasugrel compared to high-dose clopidogrel.

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Payne CD, Li YG, Small DS, Ernest CS, Farid NA, Jakubowski JA, Brandt JT, Salazar DE, and Winters KJ

Journal of cardiovascular pharmacology 50(5):555-62, 2007 Nov - Who cited this? | PubMed ID: 18030066 | Fulltext

Greater inhibition of platelet aggregation and reduced response variability with prasugrel versus clopidogrel: an integrated analysis.

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Weerakkody GJ, Jakubowski JA, Brandt JT, Payne CD, Naganuma H, and Winters KJ

Journal of cardiovascular pharmacology and therapeutics 12(3):205-12, 2007 Sep - Who cited this? | PubMed ID: 17875947 | Fulltext

Clopidogrel poor responders: an objective definition based on Bayesian classification.

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Weerakkody GJ, Brandt JT, Payne CD, Jakubowski JA, Naganuma H, and Winters KJ

Platelets 18(6):428-35, 2007 Sep - Who cited this? | PubMed ID: 17763152 | Fulltext

Comparison of speed of onset of platelet inhibition after loading doses of clopidogrel versus prasugrel in healthy volunteers and correlation with responder status.

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Weerakkody GJ, Jakubowski JA, Brandt JT, Farid NA, Payne CD, Zhu J, Warner MR, Naganuma H, and Winters KJ

The American journal of cardiology 100(2):331-6, 2007 Jul 15 - Who cited this? | PubMed ID: 17631093 | Fulltext

Cytochrome P450 3A inhibition by ketoconazole affects prasugrel and clopidogrel pharmacokinetics and pharmacodynamics differently.

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Farid NA, Payne CD, Small DS, Winters KJ, Ernest CS, Brandt JT, Darstein C, Jakubowski JA, and Salazar DE

Clinical pharmacology and therapeutics 81(5):735-41, 2007 May - Who cited this? | PubMed ID: 17361128 | Fulltext

A phase II study of the oral factor Xa inhibitor LY517717 for the prevention of venous thromboembolism after hip or knee replacement.

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Agnelli G, Haas S, Ginsberg JS, Krueger KA, Dmitrienko A, and Brandt JT

Journal of thrombosis and haemostasis : JTH 5(4):746, 2007 Apr - Who cited this? | PubMed ID: 17408408 | Fulltext

A multiple dose study of prasugrel (CS-747), a novel thienopyridine P2Y12 inhibitor, compared with clopidogrel in healthy humans.

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Jakubowski JA, Matsushima N, Asai F, Naganuma H, Brandt JT, Hirota T, Freestone S, and Winters KJ

British journal of clinical pharmacology 63(4):421-30, 2007 Apr - Who cited this? | PubMed ID: 17076696 | Fulltext

Quality assurance in hemostasis: the perspective from the College of American Pathologists proficiency testing program.

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Cunningham MT, Brandt JT, Chandler WL, Eby CS, Hayes TE, Krishnan J, Lefkowitz JB, Olson JD, Stasik CJ, Teruya J, and Van Cott EM

Seminars in thrombosis and hemostasis 33(3):250-8, 2007 Apr - Who cited this? | PubMed ID: 17427059 | Fulltext

Dose-dependent inhibition of human platelet aggregation by prasugrel and its interaction with aspirin in healthy subjects.

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Jakubowski JA, Payne CD, Weerakkody GJ, Brandt JT, Farid NA, Li YG, Naganuma H, Lachno DR, and Winters KJ

Journal of cardiovascular pharmacology 49(3):167-73, 2007 Mar - Who cited this? | PubMed ID: 17414229 | Fulltext

A comparison of prasugrel and clopidogrel loading doses on platelet function: magnitude of platelet inhibition is related to active metabolite formation.

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Brandt JT, Payne CD, Wiviott SD, Weerakkody G, Farid NA, Small DS, Jakubowski JA, Naganuma H, and Winters KJ

American heart journal 153(1):66.e9-16, 2007 Jan - Who cited this? | PubMed ID: 17174640 | Fulltext

Effect of fondaparinux on coagulation assays: results of College of American Pathologists proficiency testing.

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Smogorzewska A, Brandt JT, Chandler WL, Cunningham MT, Hayes TE, Olson JD, Kottke-Marchant K, and Van Cott EM

Archives of pathology & laboratory medicine 130(11):1605-11, 2006 Nov - Who cited this? | PubMed ID: 17076521 | Fulltext

External peer review quality assurance testing in von Willebrand disease: the recent experience of the United States College of American Pathologists proficiency testing program.

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Hayes TE, Brandt JT, Chandler WL, Eby CS, Kottke-Marchant K, Krishnan J, Lefkowitz JB, Olson JD, Rund CR, Van Cott EM, and Cunningham MT

Seminars in thrombosis and hemostasis 32(5):499-504, 2006 Jul - Who cited this? | PubMed ID: 16862523 | Fulltext

Platelet inhibitory activity and pharmacokinetics of prasugrel (CS-747) a novel thienopyridine P2Y12 inhibitor: a single ascending dose study in healthy humans.

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Asai F, Jakubowski JA, Naganuma H, Brandt JT, Matsushima N, Hirota T, Freestone S, and Winters KJ

Platelets 17(4):209-17, 2006 Jun - Who cited this? | PubMed ID: 16769598 | Fulltext

Platelet inhibitory activity and pharmacokinetics of prasugrel (CS-747) a novel thienopyridine P2Y12 inhibitor: a multiple-dose study in healthy humans.

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Matsushima N, Jakubowski JA, Asai F, Naganuma H, Brandt JT, Hirota T, Freestone S, and Winters KJ

Platelets 17(4):218-26, 2006 Jun - Who cited this? | PubMed ID: 16769599 | Fulltext

Correlation between the papanicolaou stain and the Wright-Giemsa stain in body fluids: a quality assurance study.

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Gammon RR, Kharazi M, Brandt JT, and Keyhani-Rofagha S

Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 28(3):171-4, 2006 Jun - Who cited this? | PubMed ID: 16786726 | Fulltext

Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease.

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Jernberg T, Payne CD, Winters KJ, Darstein C, Brandt JT, Jakubowski JA, Naganuma H, Siegbahn A, and Wallentin L

European heart journal 27(10):1166-73, 2006 May - Who cited this? | PubMed ID: 16621870 | Fulltext

The platelet inhibitory effects and pharmacokinetics of prasugrel after administration of loading and maintenance doses in healthy subjects.

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Jakubowski JA, Payne CD, Brandt JT, Weerakkody GJ, Farid NA, Small DS, Naganuma H, Li GY, and Winters KJ

Journal of cardiovascular pharmacology 47(3):377-84, 2006 Mar - Who cited this? | PubMed ID: 16633079 | Fulltext

Urinary desmosine as a biomarker in acute lung injury.

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Fill JA, Brandt JT, Wiedemann HP, Rinehart BL, Lindemann CF, Komara JJ, Bowsher RR, Spence MC, and Zeiher BG

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 11(1):85-96, 2006 - Who cited this? | PubMed ID: 16484139 | Fulltext

Effect of double antigen bridging immunoassay format on antigen coating concentration dependence and implications for designing immunogenicity assays for monoclonal antibodies.

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Bourdage JS, Lee TN, Taylor JM, Willey MB, Brandt JT, and Konrad RJ

Journal of pharmaceutical and biomedical analysis 39(3-4):685-90, 2005 Sep 15 - Who cited this? | PubMed ID: 15927431 | Fulltext

Differential reactivity of anti-primate and anti-human secondary antibodies against human and monkey immunoglobulins: implications for determining the sensitivity of immunogenicity assays.

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Bourdage JS, Brandt JT, Lee TN, and Konrad RJ

Journal of immunological methods 303(1-2):76-80, 2005 Aug - Who cited this? | PubMed ID: 16033697 | Fulltext

Development, validation, and implementation of a multiplex immunoassay for the simultaneous determination of five cytokines in human serum.

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Ray CA, Bowsher RR, Smith WC, Devanarayan V, Willey MB, Brandt JT, and Dean RA

Journal of pharmaceutical and biomedical analysis 36(5):1037-44, 2005 Jan 4 - Who cited this? | PubMed ID: 15620530 | Fulltext

Treatment effects of drotrecogin alfa (activated) in patients with severe sepsis with or without overt disseminated intravascular coagulation.

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Dhainaut JF, Yan SB, Joyce DE, Pettilä V, Basson B, Brandt JT, Sundin DP, and Levi M

Journal of thrombosis and haemostasis : JTH 2(11):1924-33, 2004 Nov - Who cited this? | PubMed ID: 15550023 | Fulltext

Survival advantage associated with heterozygous factor V Leiden mutation in patients with severe sepsis and in mouse endotoxemia.

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Kerlin BA, Yan SB, Isermann BH, Brandt JT, Sood R, Basson BR, Joyce DE, Weiler H, and Dhainaut JF

Blood 102(9):3085-92, 2003 Nov 1 - Who cited this? | PubMed ID: 12869495 | Fulltext

Plasminogen and tissue-type plasminogen activator deficiency as risk factors for thromboembolic disease.

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Brandt JT

Archives of pathology & laboratory medicine 126(11):1376-81, 2002 Nov - Who cited this? | PubMed ID: 12421144 | Fulltext

Laboratory diagnosis of dysfibrinogenemia.

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Cunningham MT, Brandt JT, Laposata M, and Olson JD

Archives of pathology & laboratory medicine 126(4):499-505, 2002 Apr - Who cited this? | PubMed ID: 11900586 | Fulltext

Diagnosing heparin-induced thrombocytopenia.

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Brandt JT

CAP today / College of American Pathologists 14(5):40, 44, 48, 50-52, 2000 May - Who cited this? | PubMed ID: 11066533 | Fulltext

Prevalence of the factor VLeiden mutation among autopsy patients with pulmonary thromboembolic disease using an improved method for factor VLeiden detection.

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Gorman TE, Arcot AN, Baker P, Prior TW, and Brandt JT

American journal of clinical pathology 111(3):413-7, 1999 Mar - Who cited this? | PubMed ID: 10078118 | Fulltext

A method for proficiency testing of small peer groups in the College of American Pathologists Coagulation Surveys.

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Cunningham MT, Praestgaard J, Styer PE, Brandt JT, Fairweather RB, Laposata M, Olson JD, Sosolik RC, and Triplett DA

Archives of pathology & laboratory medicine 123(3):199-205, 1999 Mar - Who cited this? | PubMed ID: 10086507 | Fulltext

Oral anticoagulants: mechanism of action, clinical effectiveness, and optimal therapeutic range.

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Hirsh J, Dalen JE, Anderson DR, Poller L, Bussey H, Ansell J, Deykin D, and Brandt JT

Chest 114(5 Suppl):445S-469S, 1998 Nov - Who cited this? | PubMed ID: 9822057 | Fulltext

College of American Pathologists Conference XXXI on laboratory monitoring of anticoagulant therapy: introduction.

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Brandt JT

Archives of pathology & laboratory medicine 122(9):765-6, 1998 Sep - Who cited this? | PubMed ID: 9740134 | Fulltext

College of American Pathologists Conference XXXI on laboratory monitoring of anticoagulant therapy: laboratory monitoring of oral anticoagulant therapy.

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Fairweather RB, Ansell J, van den Besselaar AM, Brandt JT, Bussey HI, Poller L, Triplett DA, and White RH

Archives of pathology & laboratory medicine 122(9):768-81, 1998 Sep - Who cited this? | PubMed ID: 9740135 | Fulltext

College of American Pathologists Conference XXXI on laboratory monitoring of anticoagulant therapy: laboratory monitoring of unfractionated heparin therapy.

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Olson JD, Arkin CF, Brandt JT, Cunningham MT, Giles A, Koepke JA, and Witte DL

Archives of pathology & laboratory medicine 122(9):782-98, 1998 Sep - Who cited this? | PubMed ID: 9740136 | Fulltext

Differential diagnosis of hereditary hemochromatosis from other liver disorders by genetic analysis: gene mutation analysis of patients previously diagnosed with hemochromatosis by liver biopsy.

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Bartolo C, McAndrew PE, Sosolik RC, Cawley KA, Balcerzak SP, Brandt JT, and Prior TW

Archives of pathology & laboratory medicine 122(7):633-7, 1998 Jul - Who cited this? | PubMed ID: 9674544 | Fulltext

The preoperative bleeding time test lacks clinical benefit: College of American Pathologists' and American Society of Clinical Pathologists' position article.

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Peterson P, Hayes TE, Arkin CF, Bovill EG, Fairweather RB, Rock WA, Triplett DA, and Brandt JT

Archives of surgery (Chicago, Ill. : 1960) 133(2):134-9, 1998 Feb - Who cited this? | PubMed ID: 9484723 | Fulltext

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