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Papers authored by Brady H

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The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development.

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Gascoyne DM, Long E, Veiga-Fernandes H, de Boer J, Williams O, Seddon B, Coles M, Kioussis D, and Brady HJ

Nature immunology 10(10):1118-24, 2009 Oct - Who cited this? | PubMed ID: 19749763 | Fulltext

Pomalidomide and lenalidomide induce p21 WAF-1 expression in both lymphoma and multiple myeloma through a LSD1-mediated epigenetic mechanism.

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Escoubet-Lozach L, Lin IL, Jensen-Pergakes K, Brady HA, Gandhi AK, Schafer PH, Muller GW, Worland PJ, Chan KW, and Verhelle D

Cancer research 69(18):7347-56, 2009 Sep 15 - Who cited this? | PubMed ID: 19738071 | Fulltext

The CDK inhibitor, R-roscovitine, promotes eosinophil apoptosis by down-regulation of Mcl-1.

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Duffin R, Leitch AE, Sheldrake TA, Hallett JM, Meyer C, Fox S, Alessandri AL, Martin MC, Brady HJ, Teixeira MM, Dransfield I, Haslett C, and Rossi AG

FEBS letters 583(15):2540-6, 2009 Aug 6 - Who cited this? | PubMed ID: 19616548 | Fulltext

Dicer independent small RNAs associate with telomeric heterochromatin.

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Cao F, Li X, Hiew S, Brady H, Liu Y, and Dou Y

RNA (New York, N.Y.) 15(7):1274-81, 2009 Jul - Who cited this? | PubMed ID: 19460867 | Fulltext

ERG is a megakaryocytic oncogene.

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Salek-Ardakani S, Smooha G, de Boer J, Sebire NJ, Morrow M, Rainis L, Lee S, Williams O, Izraeli S, and Brady HJ

Cancer research 69(11):4665-73, 2009 Jun 1 - Who cited this? | PubMed ID: 19487285 | Fulltext

Transcriptome of hypertension-induced left ventricular hypertrophy and its regression by antihypertensive therapies.

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Gallego-Delgado J, Connolly SB, Lázaro A, Sadlier D, Kieran NE, Sugrue DD, Doran P, Brady HR, Osende J, and Egido J

Hypertension research : official journal of the Japanese Society of Hypertension 32(5):347-57, 2009 May - Who cited this? | PubMed ID: 19325563 | Fulltext

Identification of a novel cyclin required for the intrinsic apoptosis pathway in lymphoid cells.

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Roig MB, Roset R, Ortet L, Balsiger NA, Anfosso A, Cabellos L, Garrido M, Alameda F, Brady HJ, and Gil-Gómez G

Cell death and differentiation, 2008 Oct 17 - Who cited this? | PubMed ID: 18927588 | Fulltext

IHG-1 amplifies TGF-beta1 signaling and is increased in renal fibrosis.

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Murphy M, Docherty NG, Griffin B, Howlin J, McArdle E, McMahon R, Schmid H, Kretzler M, Droguett A, Mezzano S, Brady HR, Furlong F, Godson C, and Martin F

Journal of the American Society of Nephrology : JASN 19(9):1672-80, 2008 Sep - Who cited this? | PubMed ID: 18508967 | Fulltext

The Ikaros splice isoform, Ikaros 6, immortalizes murine haematopoietic progenitor cells.

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Ruiz A, Williams O, and Brady HJ

International journal of cancer. Journal international du cancer 123(6):1240, 2008 Jul 11 - Who cited this? | PubMed ID: 18623087 | Fulltext

Ataxia telangiectasia mutated and p21CIP1 modulate cell survival of drug-induced senescent tumor cells: implications for chemotherapy.

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Crescenzi E, Palumbo G, de Boer J, and Brady HJ

Clinical cancer research : an official journal of the American Association for Cancer Research 14(6):1877-87, 2008 Mar 15 - Who cited this? | PubMed ID: 18347191 | Fulltext

Pomalidomide and lenalidomide regulate erythropoiesis and fetal hemoglobin production in human CD34+ cells.

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Moutouh-de Parseval LA, Verhelle D, Glezer E, Jensen-Pergakes K, Ferguson GD, Corral LG, Morris CL, Muller G, Brady H, and Chan K

The Journal of clinical investigation 118(1):248, 2008 Jan - Who cited this? | PubMed ID: 18064299 | Fulltext

Insights from clinical studies into the role of the MLL gene in infant and childhood leukemia.

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Chowdhury T and Brady HJ

Blood cells, molecules & diseases 40(2):192-9, 2008 - Who cited this? | PubMed ID: 17905612 | Fulltext

Mll has a critical role in fetal and adult hematopoietic stem cell self-renewal.

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McMahon KA, Hiew SY, Hadjur S, Veiga-Fernandes H, Menzel U, Price AJ, Kioussis D, Williams O, and Brady HJ

Cell stem cell 1(3):338-45, 2007 Sep 13 - Who cited this? | PubMed ID: 18371367 | Fulltext

Association of VEGF-1499C-->T polymorphism with diabetic nephropathy in type 1 diabetes mellitus.

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McKnight AJ, Maxwell AP, Patterson CC, Brady HR, and Savage DA

Journal of diabetes and its complications 21(4):242 - Who cited this? | PubMed ID: 17616354 | Fulltext

Comparison of children's diets as reported by the child via the Youth/Adolescent Questionnaire and the parent via the Willett food-frequency questionnaire.

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Lamb MM, Ross CA, Brady HL, and Norris JM

Public health nutrition 10(7):663-70, 2007 Jul - Who cited this? | PubMed ID: 17381935 | Fulltext

Plasma micronutrients are associated with dietary intake and environmental tobacco smoke exposure in a paediatric population.

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Brady H, Lamb MM, Sokol RJ, Ross CA, Seifert JA, Rewers MJ, and Norris JM

Public health nutrition 10(7):712-8, 2007 Jul - Who cited this? | PubMed ID: 17381951 | Fulltext

TEL-AML1 preleukemic activity requires the DNA binding domain of AML1 and the dimerization and corepressor binding domains of TEL.

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Morrow M, Samanta A, Kioussis D, Brady HJ, and Williams O

Oncogene 26(30):4404-14, 2007 Jun 28 - Who cited this? | PubMed ID: 17237815 | Fulltext

Immunomodulatory drug CC-4047 is a cell-type and stimulus-selective transcriptional inhibitor of cyclooxygenase 2.

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Ferguson GD, Jensen-Pergakes K, Wilkey C, Jhaveri U, Richard N, Verhelle D, De Parseval LM, Corral LG, Xie W, Morris CL, Brady H, and Chan K

Journal of clinical immunology 27(2):210-20, 2007 Mar - Who cited this? | PubMed ID: 17308870 | Fulltext

Common polymorphisms of the PAI1 gene do not play a major role in the development of diabetic nephropathy in Type 1 diabetes.

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Martin RJ, Savage DA, Patterson CC, Brady HR, and Maxwell AP

Diabetic medicine : a journal of the British Diabetic Association 24(3):259-65, 2007 Mar - Who cited this? | PubMed ID: 17263760 | Fulltext

Lenalidomide and CC-4047 inhibit the proliferation of malignant B cells while expanding normal CD34+ progenitor cells.

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Verhelle D, Corral LG, Wong K, Mueller JH, Moutouh-de Parseval L, Jensen-Pergakes K, Schafer PH, Chen R, Glezer E, Ferguson GD, Lopez-Girona A, Muller GW, Brady HA, and Chan KW

Cancer research 67(2):746, 2007 Jan 15 - Who cited this? | PubMed ID: 17234786 | Fulltext

Association between haptoglobin gene variants and diabetic nephropathy: haptoglobin polymorphism in nephropathy susceptibility.

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Conway BR, Savage DA, Brady HR, and Maxwell AP

Nephron. Experimental nephrology 105(3):e75-9, 2007 - Who cited this? | PubMed ID: 17220636 | Fulltext

Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis.

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Rossi AG, Sawatzky DA, Walker A, Ward C, Sheldrake TA, Riley NA, Caldicott A, Martinez-Losa M, Walker TR, Duffin R, Gray M, Crescenzi E, Martin MC, Brady HJ, Savill JS, Dransfield I,

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Nature medicine 12(9):1056-64, 2006 Sep - Who cited this? | PubMed ID: 16951685 | Fulltext

Emerging role of Mcl-1 in actively counteracting BH3-only proteins in apoptosis.

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Zhuang J and Brady HJ

Cell death and differentiation 13(8):1263, 2006 Aug - Who cited this? | PubMed ID: 16676002 | Fulltext

ETV4 and Myeov knockdown impairs colon cancer cell line proliferation and invasion.

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Moss AC, Lawlor G, Murray D, Tighe D, Madden SF, Mulligan AM, Keane CO, Brady HR, Doran PP, and MacMathuna P

Biochemical and biophysical research communications 345(1):216-21, 2006 Jun 23 - Who cited this? | PubMed ID: 16678123 | Fulltext

The MLL recombinome of acute leukemias.

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Meyer C, Schneider B, Jakob S, Strehl S, Attarbaschi A, Schnittger S, Schoch C, Jansen MW, van Dongen JJ, den Boer ML, Pieters R, Ennas MG, Angelucci E, Koehl U, Greil J, Griesinger F,

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Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 20(5):777-84, 2006 May - Who cited this? | PubMed ID: 16511515 | Fulltext

Mcl-1 interacts with truncated Bid and inhibits its induction of cytochrome c release and its role in receptor-mediated apoptosis.

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Clohessy JG, Zhuang J, de Boer J, Gil-Gómez G, and Brady HJ

The Journal of biological chemistry 281(9):5750-9, 2006 Mar 3 - Who cited this? | PubMed ID: 16380381 | Fulltext

A genome-wide DNA microsatellite association screen to identify chromosomal regions harboring candidate genes in diabetic nephropathy.

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McKnight AJ, Maxwell AP, Sawcer S, Compston A, Setakis E, Patterson CC, Brady HR, and Savage DA

Journal of the American Society of Nephrology : JASN 17(3):831, 2006 Mar - Who cited this? | PubMed ID: 16467450 | Fulltext

Characterization of the t(17;19) translocation by gene-specific fluorescent in situ hybridization-based cytogenetics and detection of the E2A-HLF fusion transcript and protein in patients' cells.

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Yeung J, Kempski H, Neat M, Bailey S, Smith O, and Brady HJ

Haematologica 91(3):422-4, 2006 Mar - Who cited this? | PubMed ID: 16531271 | Fulltext

Regulation of axin2 expression at the levels of transcription, translation and protein stability in lung and colon cancer.

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Hughes TA and Brady HJ

Cancer letters 233(2):338-47, 2006 Feb 28 - Who cited this? | PubMed ID: 15885887 | Fulltext

Resequencing of the characterised CTGF gene to identify novel or known variants, and analysis of their association with diabetic nephropathy.

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McKnight AJ, Savage DA, Patterson CC, Brady HR, and Maxwell AP

Journal of human genetics 51(4):383-6, 2006 - Who cited this? | PubMed ID: 16501850 | Fulltext

Microarray and bioinformatic detection of novel and established genes expressed in experimental anti-Thy1 nephritis.

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Sadlier DM, Ouyang X, McMahon B, Mu W, Ohashi R, Rodgers K, Murray D, Nakagawa T, Godson C, Doran P, Brady HR, and Johnson RJ

Kidney international 68(6):2542-61, 2005 Dec - Who cited this? | PubMed ID: 16316330 | Fulltext

Roscovitine modulates DNA repair and senescence: implications for combination chemotherapy.

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Crescenzi E, Palumbo G, and Brady HJ

Clinical cancer research : an official journal of the American Association for Cancer Research 11(22):8158-71, 2005 Nov 15 - Who cited this? | PubMed ID: 16299248 | Fulltext

Continuous MLL-ENL expression is necessary to establish a "Hox Code" and maintain immortalization of hematopoietic progenitor cells.

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Horton SJ, Grier DG, McGonigle GJ, Thompson A, Morrow M, De Silva I, Moulding DA, Kioussis D, Lappin TR, Brady HJ, and Williams O

Cancer research 65(20):9245-52, 2005 Oct 15 - Who cited this? | PubMed ID: 16230385 | Fulltext

The challenge of a multicultural environment for critical care nursing in Saudi Arabia.

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Brady H and Arabi Y

Middle East journal of anesthesiology 18(3):541-50, 2005 Oct - Who cited this? | PubMed ID: 16381260 | Fulltext

cMet and Fas receptor interaction inhibits death-inducing signaling complex formation in endothelial cells.

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Smyth LA and Brady HJ

Hypertension 46(1):100-6, 2005 Jul - Who cited this? | PubMed ID: 15911745 | Fulltext

Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy.

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Dolan V, Murphy M, Sadlier D, Lappin D, Doran P, Godson C, Martin F, O'Meara Y, Schmid H, Henger A, Kretzler M, Droguett A, Mezzano S, and Brady HR

American journal of kidney diseases : the official journal of the National Kidney Foundation 45(6):1034-9, 2005 Jun - Who cited this? | PubMed ID: 15957132 | Fulltext

E2F1 up-regulates the expression of the tumour suppressor axin2 both by activation of transcription and by mRNA stabilisation.

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Hughes TA and Brady HJ

Biochemical and biophysical research communications 329(4):1267-74, 2005 Apr 22 - Who cited this? | PubMed ID: 15766563 | Fulltext

Expression of axin2 is regulated by the alternative 5'-untranslated regions of its mRNA.

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Hughes TA and Brady HJ

The Journal of biological chemistry 280(9):8581-8, 2005 Mar 4 - Who cited this? | PubMed ID: 15611123 | Fulltext

Potentiation of glucocorticoid activity in hypoxia through induction of the glucocorticoid receptor.

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Leonard MO, Godson C, Brady HR, and Taylor CT

Journal of immunology (Baltimore, Md. : 1950) 174(4):2250-7, 2005 Feb 15 - Who cited this? | PubMed ID: 15699159 | Fulltext

Cross-talk between pRb/E2F and Wnt/beta-catenin pathways: E2F1 induces axin2 leading to repression of Wnt signalling and to increased cell death.

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Hughes TA and Brady HJ

Experimental cell research 303(1):32-46, 2005 Feb 1 - Who cited this? | PubMed ID: 15572025 | Fulltext

Connective tissue growth factor [CTGF]/CCN2 stimulates mesangial cell migration through integrated dissolution of focal adhesion complexes and activation of cell polarization.

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Crean JK, Furlong F, Finlay D, Mitchell D, Murphy M, Conway B, Brady HR, Godson C, and Martin F

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 18(13):1541, 2004 Oct - Who cited this? | PubMed ID: 15319369 | Fulltext

Cdk2 activation acts upstream of the mitochondrion during glucocorticoid induced thymocyte apoptosis.

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Granés F, Roig MB, Brady HJ, and Gil-Gómez G

European journal of immunology 34(10):2781-90, 2004 Oct - Who cited this? | PubMed ID: 15368294 | Fulltext

Role of alpha-adducin DNA polymorphisms in the genetic predisposition to diabetic nephropathy.

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Conway BR, Martin R, McKnight AJ, Savage DA, Brady HR, and Maxwell AP

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 19(8):2019-24, 2004 Aug - Who cited this? | PubMed ID: 15187197 | Fulltext

Sequential extracellular matrix-focused and baited-global cluster analysis of serial transcriptomic profiles identifies candidate modulators of renal tubulointerstitial fibrosis in murine adriamycin-induced nephropathy.

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Sadlier DM, Connolly SB, Kieran NE, Roxburgh S, Brazil DP, Kairaitis L, Wang Y, Harris DC, Doran P, and Brady HR

The Journal of biological chemistry 279(28):29670-80, 2004 Jul 9 - Who cited this? | PubMed ID: 15033991 | Fulltext

Lead identification of a potent benzopyranone selective estrogen receptor modulator.

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McKie JA, Bhagwat SS, Brady H, Doubleday M, Gayo L, Hickman M, Jalluri RK, Khammungkhune S, Kois A, Mortensen D, Richard N, Sapienza J, Shevlin G, Stein B, and Sutherland M

Bioorganic & medicinal chemistry letters 14(13):3407-10, 2004 Jul 5 - Who cited this? | PubMed ID: 15177442 | Fulltext

Ensuring quality information for patients: development and preliminary validation of a new instrument to improve the quality of written health care information.

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Moult B, Franck LS, and Brady H

Health expectations : an international journal of public participation in health care and health policy 7(2):165-75, 2004 Jun - Who cited this? | PubMed ID: 15117391 | Fulltext

E4BP4 expression is regulated by the t(17;19)-associated oncoprotein E2A-HLF in pro-B cells.

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Yeung J, O'Sullivan E, Hubank M, and Brady HJ

British journal of haematology 125(5):560-7, 2004 Jun - Who cited this? | PubMed ID: 15147370 | Fulltext

Characterisation of Mcl-1 cleavage during apoptosis of haematopoietic cells.

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Clohessy JG, Zhuang J, and Brady HJ

British journal of haematology 125(5):655-65, 2004 Jun - Who cited this? | PubMed ID: 15147382 | Fulltext

TEL-AML1 promotes development of specific hematopoietic lineages consistent with preleukemic activity.

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Morrow M, Horton S, Kioussis D, Brady HJ, and Williams O

Blood 103(10):3890-6, 2004 May 15 - Who cited this? | PubMed ID: 14726384 | Fulltext

Overexpression of the Ikaros 6 isoform is restricted to t(4;11) acute lymphoblastic leukaemia in children and infants and has a role in B-cell survival.

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Ruiz A, Jiang J, Kempski H, and Brady HJ

British journal of haematology 125(1):31-7, 2004 Apr - Who cited this? | PubMed ID: 15015965 | Fulltext

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