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Papers authored by Bottomley J

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Risk of birth defects increased in pregnancies conceived by assisted human reproduction.

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El-Chaar D, Yang Q, Gao J, Bottomley J, Leader A, Wen SW, and Walker M

Fertility and sterility 92(5):1557-61, 2009 Nov - Who cited this? | PubMed ID: 18973885 | Fulltext

Reply of the Authors: Risk of birth defects increased in pregnancies conceived by assisted human reproduction.

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El-Chaar D, Yang Q, Bottomley J, Leader A, Wen SW, and Walker M

Fertility and sterility 92(1):e8, 2009 Jul - Who cited this? | PubMed ID: 19501820 | Fulltext

Pregnancy Outcomes in Diabetes Subtypes: How Do They Compare? A Province-based Study of Ontario, 2005-2006.

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Peticca P, Keely EJ, Walker MC, Yang Q, and Bottomley J

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC 31(6):487-96, 2009 Jun - Who cited this? | PubMed ID: 19646313 | Fulltext

In Vitro Fertilization is Associated with an Increased Risk for Preeclampsia.

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Chen XK, Wen SW, Bottomley J, Smith GN, Leader A, and Walker MC

Hypertension in pregnancy : official journal of the International Society for the Study of Hypertension in Pregnancy 28(1):1-12, 2009 Feb - Who cited this? | PubMed ID: 19165665 | Fulltext

Utilization of health care services of pregnant women complicated by preeclampsia in ontario.

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Liu A, Wen SW, Bottomley J, Walker MC, and Smith G

Hypertension in pregnancy : official journal of the International Society for the Study of Hypertension in Pregnancy 28(1):76-84, 2009 Feb - Who cited this? | PubMed ID: 19165672 | Fulltext

A Globally Optimal k-Anonymity Method for the De-Identification of Health Data.

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El Emam K, Dankar FK, Issa R, Jonker E, Amyot D, Cogo E, Corriveau JP, Walker M, Chowdhury S, Vaillancourt R, Roffey T, and Bottomley J

Journal of the American Medical Informatics Association : JAMIA 16(5):670-82, 2009 - Who cited this? | PubMed ID: 19567795 | Fulltext

Metastatic gestational trophoblastic tumour presenting as spontaneous subcapsular renal haematoma.

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Vijay RK, Kaduthodil MJ, Bottomley JR, and Abdi S

The British journal of radiology 81(969):e234-7, 2008 Sep - Who cited this? | PubMed ID: 18769012 | Fulltext

Pharmaco-economic issues for diabetes therapy.

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Bottomley JM and Raymond FD

Best practice & research. Clinical endocrinology & metabolism 21(4):657, 2007 Dec - Who cited this? | PubMed ID: 18054741 | Fulltext

PROactive 06: cost-effectiveness of pioglitazone in Type 2 diabetes in the UK.

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Valentine WJ, Bottomley JM, Palmer AJ, Brändle M, Foos V, Williams R, Dormandy JA, Yates J, Tan MH, Massi-Benedetti M, and PROactive Study Group

Diabetic medicine : a journal of the British Diabetic Association 24(9):982-1002, 2007 Sep - Who cited this? | PubMed ID: 17593245 | Fulltext

Cost-effectiveness of the two-compound formulation calcipotriol and betamethasone dipropionate compared with commonly used topical treatments in the management of moderately severe plaque psoriasis in Scotland.

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Bottomley JM, Auland ME, Morais J, Boyd G, and Douglas WS

Current medical research and opinion 23(8):1887-901, 2007 Aug - Who cited this? | PubMed ID: 17610804 | Fulltext

A lifetime modelled economic evaluation comparing pioglitazone and rosiglitazone for the treatment of type 2 diabetes mellitus in the UK.

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Tilden DP, Mariz S, O'Bryan-Tear G, Bottomley J, and Diamantopoulos A

PharmacoEconomics 25(1):39-54, 2007 - Who cited this? | PubMed ID: 17192117 | Fulltext

Long-term retrievability of IVC filters: should we abandon permanent devices?.

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Berczi V, Bottomley JR, Thomas SM, Taneja S, Gaines PA, and Cleveland TJ

Cardiovascular and interventional radiology 30(5):820-7, 2007 - Who cited this? | PubMed ID: 17763901 | Fulltext

The impact of clinical audit on antibiotic prescribing in general dental practice.

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Chate RA, White S, Hale LR, Howat AP, Bottomley J, Barnet-Lamb J, Lindsay J, Davies TI, and Heath JM

British dental journal 201(10):635-41, 2006 Nov 25 - Who cited this? | PubMed ID: 17128233 | Fulltext

Stent implantation for acute iliac artery occlusions: initial experience.

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Berczi V, Thomas SM, Turner DR, Bottomley JR, Cleveland TJ, and Gaines PA

Journal of vascular and interventional radiology : JVIR 17(4):645-9, 2006 Apr - Who cited this? | PubMed ID: 16614147 | Fulltext

Endovascular embolization of visceral artery aneurysms with ethylene-vinyl alcohol (Onyx): a case series.

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Bratby MJ, Lehmann ED, Bottomley J, Kessel DO, Nicholson AA, McPherson SJ, Morgan RA, and Belli AM

Cardiovascular and interventional radiology 29(6):1125-8, 2006 - Who cited this? | PubMed ID: 16625409 | Fulltext

Do people with type 2 diabetes and their carers lose income? (T2ARDIS-4).

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Holmes J, Gear E, Bottomley J, Gillam S, Murphy M, and Williams R

Health policy (Amsterdam, Netherlands) 64(3):291-6, 2003 Jun - Who cited this? | PubMed ID: 12745168 | Fulltext

A series of 2(Z)-2-benzylidene-6,7-dihydroxybenzofuran-3[2H]-ones as inhibitors of chorismate synthase.

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Thomas MG, Lawson C, Allanson NM, Leslie BW, Bottomley JR, McBride A, and Olusanya OA

Bioorganic & medicinal chemistry letters 13(3):423-6, 2003 Feb 10 - Who cited this? | PubMed ID: 12565943 | Fulltext

GAP1IP4BP contains a novel group I pleckstrin homology domain that directs constitutive plasma membrane association.

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Cozier GE, Lockyer PJ, Reynolds JS, Kupzig S, Bottomley JR, Millard TH, Banting G, and Cullen PJ

The Journal of biological chemistry 275(36):28261-8, 2000 Sep 8 - Who cited this? | PubMed ID: 10869341 | Fulltext

Molecular modelling and site-directed mutagenesis of the inositol 1,3,4,5-tetrakisphosphate-binding pleckstrin homology domain from the Ras GTPase-activating protein GAP1IP4BP.

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Cozier G, Sessions R, Bottomley JR, Reynolds JS, and Cullen PJ

The Biochemical journal 349(Pt 1):333-42, 2000 Jul 1 - Who cited this? | PubMed ID: 10861245 | Fulltext

Equilibrium and kinetic studies of substrate binding to 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Escherichia coli.

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Bermingham A, Bottomley JR, Primrose WU, and Derrick JP

The Journal of biological chemistry 275(24):17962-7, 2000 Jun 16 - Who cited this? | PubMed ID: 10751386 | Fulltext

Health-related quality of life in type 2 diabetes (TARDIS-2).

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Holmes J, McGill S, Kind P, Bottomley J, Gillam S, and Murphy M

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 3 Suppl 1:47-51, 2000 - Who cited this? | PubMed ID: 16464209 | Fulltext

Structural and functional analysis of the putative inositol 1,3,4, 5-tetrakisphosphate receptors GAP1(IP4BP) and GAP1(m).

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Bottomley JR, Reynolds JS, Lockyer PJ, and Cullen PJ

Biochemical and biophysical research communications 250(1):143-9, 1998 Sep 8 - Who cited this? | PubMed ID: 9735347 | Fulltext

Modulation of Ins(2,4,5)P3-stimulated Ca2+ mobilization by ins(1,3,4, 5)P4: enhancement by activated G-proteins, and evidence for the involvement of a GAP1 protein, a putative Ins(1,3,4,5)P4 receptor.

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Loomis-Husselbee JW, Walker CD, Bottomley JR, Cullen PJ, Irvine RF, and Dawson AP

The Biochemical journal 331 ( Pt 3):947-52, 1998 May 1 - Who cited this? | PubMed ID: 9560326 | Fulltext

Distinct subcellular localisations of the putative inositol 1,3,4,5-tetrakisphosphate receptors GAP1IP4BP and GAP1m result from the GAP1IP4BP PH domain directing plasma membrane targeting.

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Lockyer PJ, Bottomley JR, Reynolds JS, McNulty TJ, Venkateswarlu K, Potter BV, Dempsey CE, and Cullen PJ

Current biology : CB 7(12):1007-10, 1997 Dec 1 - Who cited this? | PubMed ID: 9382842 | Fulltext

Cloning, sequencing, expression, purification and preliminary characterization of a type II dehydroquinase from Helicobacter pylori.

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Bottomley JR, Clayton CL, Chalk PA, and Kleanthous C

The Biochemical journal 319 ( Pt 2):559-65, 1996 Oct 15 - Who cited this? | PubMed ID: 8912695 | Fulltext

Conformational changes and the role of metals in the mechanism of type II dehydroquinase from Aspergillus nidulans.

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Bottomley JR, Hawkins AR, and Kleanthous C

The Biochemical journal 319 ( Pt 1):269-78, 1996 Oct 1 - Who cited this? | PubMed ID: 8870678 | Fulltext

Dentofacial form in the five-year-old child with unilateral cleft lip and palate.

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Mackay F, Bottomley J, Semb G, and Roberts C

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 31(5):372-5, 1994 Sep - Who cited this? | PubMed ID: 7986798 | Fulltext

Ropinirole (SK and F 101468) in the treatment of Parkinson's disease.

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Kleedorfer B, Stern GM, Lees AJ, Bottomley JM, and Sree-Haran N

Journal of neurology, neurosurgery, and psychiatry 54(10):938, 1991 Oct - Who cited this? | PubMed ID: 1683897 | Fulltext

Dyspepsia in England and Scotland.

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Jones RH, Lydeard SE, Hobbs FD, Kenkre JE, Williams EI, Jones SJ, Repper JA, Caldow JL, Dunwoodie WM, and Bottomley JM

Gut 31(4):401-5, 1990 Apr - Who cited this? | PubMed ID: 2338264 | Fulltext

The dimensional stability of self-disinfecting alginate impressions compared to various immersion regimes.

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Jones ML, Newcombe RG, Bellis H, and Bottomley J

The Angle orthodontist 60(2):123-8, 1990 - Who cited this? | PubMed ID: 2111646 | Fulltext

Treatment of Parkinson's disease with novel dopamine D2 agonist SK&F 101468.

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Kapoon R, Pirtosek Z, Frankel JP, Stern GM, Lees AJ, Bottomley JM, and Haran NS

Lancet 1(8652):1445-6, 1989 Jun 24 - Who cited this? | PubMed ID: 2567448 | Fulltext

Cimetidine-nicoumalone interaction in man: stereochemical considerations.

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Gill TS, Hopkins KJ, Bottomley J, Gupta SK, and Rowland M

British journal of clinical pharmacology 27(4):469-74, 1989 Apr - Who cited this? | PubMed ID: 2719902 | Fulltext

Unexplained spontaneous regression and alpha-interferon as treatment for metastatic renal carcinoma.

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Oliver RT, Nethersell AB, and Bottomley JM

British journal of urology 63(2):128-31, 1989 Feb - Who cited this? | PubMed ID: 2702395 | Fulltext

A Reflex Plotter investigation into the dimensional stability of alginate impressions following disinfection by varying regimes employing 2.2 per cent glutaraldehyde.

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Jones ML, Newcombe RG, Barry G, Bellis H, and Bottomley J

British journal of orthodontics 15(3):185-92, 1988 Aug - Who cited this? | PubMed ID: 3139024 | Fulltext

Treatment of myelodysplasia with alpha-interferon.

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Galvani D, Nethersell A, and Bottomley J

Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1(11):786-7, 1987 Nov - Who cited this? | PubMed ID: 3479666 | Fulltext

The graying of America. Opportunities for physical therapy.

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Jette AM and Bottomley JM

Physical therapy 67(10):1537-42, 1987 Oct - Who cited this? | PubMed ID: 2958888 | Fulltext

Natural IFN-alpha therapy in hairy-cell leukaemia (namalva-type IFN--Wellferon).

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Worman CP, Nethersell AB, Bottomley JM, Apostolov K, Barker W, and Cawley JC

Klinische Wochenschrift 65(14):685-7, 1987 Jul 15 - Who cited this? | PubMed ID: 3306138 | Fulltext

Alpha-interferon in myelodysplasia.

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Galvani DW, Cawley JC, Nethersell A, and Bottomley JM

British journal of haematology 66(1):145-6, 1987 May - Who cited this? | PubMed ID: 3593652 | Fulltext

The U.K. experience with human lymphoblastoid interferon in HCL: a report of the first 50 cases.

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Worman CP, Catovsky D, Cawley JC, Bevan PC, Bottomley JM, and Nethersell AB

Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1(4):320-2, 1987 Apr - Who cited this? | PubMed ID: 3669754 | Fulltext

Successful use of interferon alfa-n1 in the treatment of hairy cell leukemia.

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Cawley JC, Bottomley JM, and Worman CP

The Medical clinics of North America Suppl:37-9, 1986 May - Who cited this? | PubMed ID: 3488481 | Fulltext

Combining interferon with cytotoxic chemotherapy in patients with advanced breast cancer.

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Ashford R, Priestman T, Mott T, and Bottomley JM

Cancer immunology, immunotherapy : CII 23(3):217-9, 1986 - Who cited this? | PubMed ID: 3791306 | Fulltext

Interferon is effective in hairy-cell leukaemia.

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Worman CP, Catovsky D, Bevan PC, Camba L, Joyner M, Green PJ, Williams HJ, Bottomley JM, Gordon-Smith EC, and Cawley JC

British journal of haematology 60(4):759-63, 1985 Aug - Who cited this? | PubMed ID: 3875366 | Fulltext

Fibrinogen Manchester. Detection of a heterozygous phenotype in the intraplatelet pool.

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Southan C, Lane DA, Knight I, Ireland H, and Bottomley J

The Biochemical journal 229(3):723-30, 1985 Aug 1 - Who cited this? | PubMed ID: 4052020 | Fulltext

Congenital factor XII deficiency: successful open heart surgery and anticoagulation.

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Kelsey PR, Bottomley J, Grotte GJ, and Maciver JE

Clinical and laboratory haematology 7(4):379-81, 1985 - Who cited this? | PubMed ID: 3879475 | Fulltext

Platelet lipid composition in human migraine.

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Bottomley JM, Hanington E, Jones RJ, and Chapman D

Headache 22(6):256-60, 1982 Nov - Who cited this? | PubMed ID: 7174302 | Fulltext

Comparison of liquid and dried sodium citrate as the anticoagulant for Thrombotest and prothrombin time estimations.

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Hoctor D, Bottomley J, Hyde K, Gowenlock AH, and Maciver JE

Journal of clinical pathology 34(8):902-5, 1981 Aug - Who cited this? | PubMed ID: 7276209 | Fulltext

Cholesterol depletion from baiomembranes of murine lymphocytes and human tonsil lymphocytes. Transformation effects.

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Bottomley JM, Kramers MT, and Chapman D

FEBS letters 119(2):261-4, 1980 Oct 6 - Who cited this? | PubMed ID: 7428938 | Fulltext

Studies of liposome interactions with rat thymocytes.

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Kramers MT, Patrick J, Bottomley JM, Quinn PJ, and Chapman D

European journal of biochemistry / FEBS 110(2):579-85, 1980 Sep - Who cited this? | PubMed ID: 7439175 | Fulltext

Practolol therapy associated with a systemic lupus erythematosus-like syndrome and an inhibitor to factor XIII.

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Milner GR, Holt PJ, Bottomley J, and Maciver JE

Journal of clinical pathology 30(8):770-3, 1977 Aug - Who cited this? | PubMed ID: 599192 | Fulltext

Dimer X in hysterosalpingography.

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Markham GC, Bottomley JP, and Ansell G

The British journal of radiology 50(590):101-4, 1977 Feb - Who cited this? | PubMed ID: 318881 | Fulltext

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