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Papers authored by Bodine PV

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Secreted frizzled related protein 1 is a target to improve fracture healing.

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Gaur T, Wixted JJ, Hussain S, O'Connell SL, Morgan EF, Ayers DC, Komm BS, Bodine PV, Stein GS, and Lian JB

Journal of cellular physiology 220(1):174-81, 2009 Jul - Who cited this? | PubMed ID: 19301255 | Fulltext

A small molecule inhibitor of the Wnt antagonist secreted frizzled-related protein-1 stimulates bone formation.

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Bodine PV, Stauffer B, Ponce-de-Leon H, Bhat RA, Mangine A, Seestaller-Wehr LM, Moran RA, Billiard J, Fukayama S, Komm BS, Pitts K, Krishnamurthy G, Gopalsamy A, Shi M, Kern JC, Commons TJ,

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Bone 44(6):1063-8, 2009 Jun - Who cited this? | PubMed ID: 19254787 | Fulltext

Parathyroid hormone synergizes with non-cyclic AMP pathways to activate the cyclic AMP response element.

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Murrills RJ, Andrews JL, Samuel RL, Coleburn VE, Bhat BM, Bhat RA, Bex FJ, and Bodine PV

Journal of cellular biochemistry 106(5):887-95, 2009 Apr 1 - Who cited this? | PubMed ID: 19180574 | Fulltext

Modulation of Wnt signaling through inhibition of secreted frizzled-related protein I (sFRP-1) with N-substituted piperidinyl diphenylsulfonyl sulfonamides.

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Moore WJ, Kern JC, Bhat R, Commons TJ, Fukayama S, Goljer I, Krishnamurthy G, Magolda RL, Nogle L, Pitts K, Stauffer B, Trybulski EJ, Welmaker GS, Wilson M, and Bodine PV

Journal of medicinal chemistry 52(1):105-16, 2009 Jan 8 - Who cited this? | PubMed ID: 19072540 | Fulltext

The pairing of a selective estrogen receptor modulator, bazedoxifene, with conjugated estrogens as a new paradigm for the treatment of menopausal symptoms and osteoporosis prevention.

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Kharode Y, Bodine PV, Miller CP, Lyttle CR, and Komm BS

Endocrinology 149(12):6084-91, 2008 Dec - Who cited this? | PubMed ID: 18703623 | Fulltext

Wnt5a induces homodimerization and activation of Ror2 receptor tyrosine kinase.

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Liu Y, Rubin B, Bodine PV, and Billiard J

Journal of cellular biochemistry, 2008 Jul 9 - Who cited this? | PubMed ID: 18615587 | Fulltext

Expression of secreted frizzled related protein 1, a Wnt antagonist, in brain, kidney, and skeleton is dispensable for normal embryonic development.

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Trevant B, Gaur T, Hussain S, Symons J, Komm BS, Bodine PV, Stein GS, and Lian JB

Journal of cellular physiology 217(1):113, 2008 May 22 - Who cited this? | PubMed ID: 18498122 | Fulltext

Wnt signaling control of bone cell apoptosis.

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Bodine PV

Cell research 18(2):248-53, 2008 Feb - Who cited this? | PubMed ID: 18212734 | Fulltext

Utility of the ovariectomized rat as a model for human osteoporosis in drug discovery.

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Kharode YP, Sharp MC, and Bodine PV

Methods in molecular biology (Clifton, N.J.) 455:111, 2008 - Who cited this? | PubMed ID: 18463814 | Fulltext

Turning genetic discoveries into new treatments: The Wnt/LRP-5 system as a source of new drug targets for skeletal diseases.

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Bodine PV

Journal of musculoskeletal & neuronal interactions 8(4):296-7, 2008 - Who cited this? | PubMed ID: 19147946 | Fulltext

Ror2, a novel modulator of osteogenesis.

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Liu Y, Bodine PV, and Billiard J

Journal of musculoskeletal & neuronal interactions 7(4):323 - Who cited this? | PubMed ID: 18094493 | Fulltext

Structure-function analysis of secreted frizzled-related protein-1 for its Wnt antagonist function.

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Bhat RA, Stauffer B, Komm BS, and Bodine PV

Journal of cellular biochemistry 102(6):1519, 2007 Dec 15 - Who cited this? | PubMed ID: 17471511 | Fulltext

Homodimerization of Ror2 tyrosine kinase receptor induces 14-3-3(beta) phosphorylation and promotes osteoblast differentiation and bone formation.

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Liu Y, Ross JF, Bodine PV, and Billiard J

Molecular endocrinology (Baltimore, Md.) 21(12):3050, 2007 Dec - Who cited this? | PubMed ID: 17717073 | Fulltext

The orphan receptor tyrosine kinase Ror2 promotes osteoblast differentiation and enhances ex vivo bone formation.

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Liu Y, Bhat RA, Seestaller-Wehr LM, Fukayama S, Mangine A, Moran RA, Komm BS, Bodine PV, and Billiard J

Molecular endocrinology (Baltimore, Md.) 21(2):376, 2007 Feb - Who cited this? | PubMed ID: 17095577 | Fulltext

Bone anabolic effects of parathyroid hormone are blunted by deletion of the Wnt antagonist secreted frizzled-related protein-1.

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Bodine PV, Seestaller-Wehr L, Kharode YP, Bex FJ, and Komm BS

Journal of cellular physiology 210(2):352-7, 2007 Feb - Who cited this? | PubMed ID: 17044082 | Fulltext

Secreted frizzled related protein 1 regulates Wnt signaling for BMP2 induced chondrocyte differentiation.

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Gaur T, Rich L, Lengner CJ, Hussain S, Trevant B, Ayers D, Stein JL, Bodine PV, Komm BS, Stein GS, and Lian JB

Journal of cellular physiology 208(1):87-96, 2006 Jul - Who cited this? | PubMed ID: 16575902 | Fulltext

Wnt signaling and osteoblastogenesis.

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Bodine PV and Komm BS

Reviews in endocrine & metabolic disorders 7(1-2):33, 2006 Jun - Who cited this? | PubMed ID: 16960757 | Fulltext

The Wnt antagonist secreted frizzled-related protein-1 controls osteoblast and osteocyte apoptosis.

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Bodine PV, Billiard J, Moran RA, Ponce-de-Leon H, McLarney S, Mangine A, Scrimo MJ, Bhat RA, Stauffer B, Green J, Stein GS, Lian JB, and Komm BS

Journal of cellular biochemistry 96(6):1212-30, 2005 Dec 15 - Who cited this? | PubMed ID: 16149051 | Fulltext

Canonical WNT signaling promotes osteogenesis by directly stimulating Runx2 gene expression.

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Gaur T, Lengner CJ, Hovhannisyan H, Bhat RA, Bodine PV, Komm BS, Javed A, van Wijnen AJ, Stein JL, Stein GS, and Lian JB

The Journal of biological chemistry 280(39):33132, 2005 Sep 30 - Who cited this? | PubMed ID: 16043491 | Fulltext

Bazedoxifene acetate: a selective estrogen receptor modulator with improved selectivity.

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Komm BS, Kharode YP, Bodine PV, Harris HA, Miller CP, and Lyttle CR

Endocrinology 146(9):3999, 2005 Sep - Who cited this? | PubMed ID: 15961563 | Fulltext

The orphan receptor tyrosine kinase Ror2 modulates canonical Wnt signaling in osteoblastic cells.

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Billiard J, Way DS, Seestaller-Wehr LM, Moran RA, Mangine A, and Bodine PV

Molecular endocrinology (Baltimore, Md.) 19(1):90-101, 2005 Jan - Who cited this? | PubMed ID: 15388793 | Fulltext

Regulated expression of sFRP-1 protein by the GeneSwitch system.

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Bhat RA, Stauffer B, Komm BS, and Bodine PV

Protein expression and purification 37(2):327-35, 2004 Oct - Who cited this? | PubMed ID: 15358354 | Fulltext

The Wnt antagonist secreted frizzled-related protein-1 is a negative regulator of trabecular bone formation in adult mice.

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Bodine PV, Zhao W, Kharode YP, Bex FJ, Lambert AJ, Goad MB, Gaur T, Stein GS, Lian JB, and Komm BS

Molecular endocrinology (Baltimore, Md.) 18(5):1222-37, 2004 May - Who cited this? | PubMed ID: 14976225 | Fulltext

Glucocorticoids induce glutamine synthetase expression in human osteoblastic cells: a novel observation in bone.

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Olkku A, Bodine PV, Linnala-Kankkunen A, and Mahonen A

Bone 34(2):320-9, 2004 Feb - Who cited this? | PubMed ID: 14962810 | Fulltext

High bone mass in mice expressing a mutant LRP5 gene.

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Babij P, Zhao W, Small C, Kharode Y, Yaworsky PJ, Bouxsein ML, Reddy PS, Bodine PV, Robinson JA, Bhat B, Marzolf J, Moran RA, and Bex F

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 18(6):960-74, 2003 Jun - Who cited this? | PubMed ID: 12817748 | Fulltext

Transcriptional profiling of human osteoblast differentiation.

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Billiard J, Moran RA, Whitley MZ, Chatterjee-Kishore M, Gillis K, Brown EL, Komm BS, and Bodine PV

Journal of cellular biochemistry 89(2):389-400, 2003 May 15 - Who cited this? | PubMed ID: 12704802 | Fulltext

Estrogens activate bone morphogenetic protein-2 gene transcription in mouse mesenchymal stem cells.

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Zhou S, Turgeman G, Harris SE, Leitman DC, Komm BS, Bodine PV, and Gazit D

Molecular endocrinology (Baltimore, Md.) 17(1):56-66, 2003 Jan - Who cited this? | PubMed ID: 12511606 | Fulltext

PTH-dependent adenylyl cyclase activation in SaOS-2 cells: passage dependent effects on G protein interactions.

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Gao H, Bodine PV, Murrills R, Bex FJ, Bilezikian JP, and Morris SA

Journal of cellular physiology 193(1):10-8, 2002 Oct - Who cited this? | PubMed ID: 12209875 | Fulltext

Estrogenic effects of 7alpha-methyl-17alpha-ethynylestradiol: a newly discovered tibolone metabolite.

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Bodine PV, Harris HA, Lyttle CR, and Komm BS

Steroids 67(8):681-6, 2002 Jul - Who cited this? | PubMed ID: 12117614 | Fulltext

Signal transduction pathways involved in macrophage migration induced by peritoneal fluid chemotactic factors in stages I and II endometriosis.

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Perez MC, Bodine PV, Leiva MC, Isaacson KB, and Komm BS

Fertility and sterility 77(6):1261-8, 2002 Jun - Who cited this? | PubMed ID: 12057738 | Fulltext

Tissue culture models for studies of hormone and vitamin action in bone cells.

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Bodine PV and Komm BS

Vitamins and hormones 64:101-51, 2002 - Who cited this? | PubMed ID: 11898390 | Fulltext

Systemically administered rhBMP-2 promotes MSC activity and reverses bone and cartilage loss in osteopenic mice.

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Turgeman G, Zilberman Y, Zhou S, Kelly P, Moutsatsos IK, Kharode YP, Borella LE, Bex FJ, Komm BS, Bodine PV, and Gazit D

Journal of cellular biochemistry 86(3):461-74, 2002 - Who cited this? | PubMed ID: 12210753 | Fulltext

Expression and regulation of Runx2/Cbfa1 and osteoblast phenotypic markers during the growth and differentiation of human osteoblasts.

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Prince M, Banerjee C, Javed A, Green J, Lian JB, Stein GS, Bodine PV, and Komm BS

Journal of cellular biochemistry 80(3):424-40, 2001 - Who cited this? | PubMed ID: 11135373 | Fulltext

Evidence that conditionally immortalized human osteoblasts express an osteocalcin receptor.

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Bodine PV and Komm BS

Bone 25(5):535-43, 1999 Nov - Who cited this? | PubMed ID: 10574573 | Fulltext

Suppression of ligand-dependent estrogen receptor activity by bone-resorbing cytokines in human osteoblasts.

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Bodine PV, Harris HA, and Komm BS

Endocrinology 140(6):2439-51, 1999 Jun - Who cited this? | PubMed ID: 10342828 | Fulltext

Estrogen receptor-alpha is developmentally regulated during osteoblast differentiation and contributes to selective responsiveness of gene expression.

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Bodine PV, Henderson RA, Green J, Aronow M, Owen T, Stein GS, Lian JB, and Komm BS

Endocrinology 139(4):2048-57, 1998 Apr - Who cited this? | PubMed ID: 9528993 | Fulltext

The ongoing saga of osteoporosis treatment.

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Komm BS and Bodine PV

Journal of cellular biochemistry. Supplement 30-31:277-83, 1998 - Who cited this? | PubMed ID: 9893280 | Fulltext

Functional properties of a conditionally phenotypic, estrogen-responsive, human osteoblast cell line.

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Bodine PV, Green J, Harris HA, Bhat RA, Stein GS, Lian JB, and Komm BS

Journal of cellular biochemistry 65(3):368-87, 1997 Jun 1 - Who cited this? | PubMed ID: 9138093 | Fulltext

Establishment and hormonal regulation of a conditionally transformed preosteocytic cell line from adult human bone.

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Bodine PV, Vernon SK, and Komm BS

Endocrinology 137(11):4592-604, 1996 Nov - Who cited this? | PubMed ID: 8895322 | Fulltext

Development and characterization of a conditionally transformed adult human osteoblastic cell line.

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Bodine PV, Trailsmith M, and Komm BS

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 11(6):806-19, 1996 Jun - Who cited this? | PubMed ID: 8725178 | Fulltext

Modulator inhibits nuclear translocation of the glucocorticoid receptor and inhibits glucocorticoid-induced apoptosis in the human leukemic cell line CEM C-7.

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Robertson NM, Bodine PV, Hsu TC, Alnemri ES, and Litwack G

Cancer research 55(3):548-56, 1995 Feb 1 - Who cited this? | PubMed ID: 7834624 | Fulltext

Regulation of c-fos expression and TGF-beta production by gonadal and adrenal androgens in normal human osteoblastic cells.

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Bodine PV, Riggs BL, and Spelsberg TC

The Journal of steroid biochemistry and molecular biology 52(2):149-58, 1995 Feb - Who cited this? | PubMed ID: 7873450 | Fulltext

Synthetic peptides derived from the steroid binding domain block modulator and molybdate action toward the rat glucocorticoid receptor.

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Bodine PV, Alnemri ES, and Litwack G

Receptor 5(2):117-22, 1995 - Who cited this? | PubMed ID: 7580937 | Fulltext

Purification of the glucocorticoid receptor-mineralocorticoid receptor modulator-2 from rabbit liver.

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Bodine PV and Litwack G

Receptor 5(3):133-43, 1995 - Who cited this? | PubMed ID: 8729193 | Fulltext

A new synthetic ether aminophosphoglyceride exhibits partial modulator activity towards the glucocorticoid receptor.

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Bodine PV, Hajdu J, and Litwack G

Biochemical and biophysical research communications 203(1):408-15, 1994 Aug 30 - Who cited this? | PubMed ID: 8074685 | Fulltext

Modulators of the glucocorticoid receptor also regulate mineralocorticoid receptor function.

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Schulman G, Bodine PV, and Litwack G

Biochemistry 31(6):1734-41, 1992 Feb 18 - Who cited this? | PubMed ID: 1310618 | Fulltext

Endogenous modulators of glucocorticoid receptor function also regulate purified protein kinase C.

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Hsu TC, Bodine PV, and Litwack G

The Journal of biological chemistry 266(26):17573-9, 1991 Sep 15 - Who cited this? | PubMed ID: 1894640 | Fulltext

Evaluation of synthetic novel ether aminophosphoglycerides for glucocorticoid-receptor complex modulator activity.

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Bodine PV, Garcia ML, Pascual J, Bastida E, Carganico G, and Litwack G

Receptor 1(3):167-80, 1991 - Who cited this? | PubMed ID: 1843206 | Fulltext

Modulator: the missing link.

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Bodine PV and Litwack G

Molecular and cellular endocrinology 74(1):C77-81, 1990 Nov 12 - Who cited this? | PubMed ID: 2178104 | Fulltext

Purification and characterization of two novel phosphoglycerides that modulate the glucocorticoid-receptor complex. Evidence for two modulator binding sites in the occupied/unactivated steroid hormone receptor.

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Bodine PV and Litwack G

The Journal of biological chemistry 265(16):9544-54, 1990 Jun 5 - Who cited this? | PubMed ID: 2345182 | Fulltext

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