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Papers authored by Björnstedt M

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Cancer cell death induced by phosphine gold(I) compounds targeting thioredoxin reductase.

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Gandin V, Fernandes AP, Rigobello MP, Dani B, Sorrentino F, Tisato F, Björnstedt M, Bindoli A, Sturaro A, Rella R, and Marzano C

Biochemical pharmacology 79(2):90-101, 2010 Jan 15 - Who cited this? | PubMed ID: 19665452 | Fulltext

Treatment of human cancer cells with selenite or tellurite in combination with auranofin enhances cell death due to redox shift.

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Rigobello MP, Gandin V, Folda A, Rundlöf AK, Fernandes AP, Bindoli A, Marzano C, and Björnstedt M

Free radical biology & medicine 47(6):710-21, 2009 Sep 15 - Who cited this? | PubMed ID: 19486940 | Fulltext

Selenite is a potent cytotoxic agent for human primary AML cells.

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Olm E, Jönsson-Videsäter K, Ribera-Cortada I, Fernandes AP, Eriksson LC, Lehmann S, Rundlöf AK, Paul C, and Björnstedt M

Cancer letters 282(1):116-23, 2009 Sep 8 - Who cited this? | PubMed ID: 19345479 | Fulltext

Expression profiles of thioredoxin family proteins in human lung cancer tissue: correlation with proliferation and differentiation.

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Fernandes AP, Capitanio A, Selenius M, Brodin O, Rundlöf AK, and Björnstedt M

Histopathology 55(3):313-20, 2009 Sep - Who cited this? | PubMed ID: 19723146 | Fulltext

Extracellular thiol-assisted selenium uptake dependent on the x(c)- cystine transporter explains the cancer-specific cytotoxicity of selenite.

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Olm E, Fernandes AP, Hebert C, Rundlöf AK, Larsen EH, Danielsson O, and Björnstedt M

Proceedings of the National Academy of Sciences of the United States of America 106(27):11400-5, 2009 Jul 7 - Who cited this? | PubMed ID: 19549867 | Fulltext

Effects of the antioxidant Pycnogenol on cellular redox systems in U1285 human lung carcinoma cells.

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Gandin V, Nyström C, Rundlöf AK, Jönsson-Videsäter K, Schönlau F, Hörkkö J, Björnstedt M, and Fernandes AP

The FEBS journal 276(2):532-40, 2009 Jan - Who cited this? | PubMed ID: 19077163 | Fulltext

Phenotype-dependent apoptosis signalling in mesothelioma cells after selenite exposure.

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Nilsonne G, Olm E, Szulkin A, Mundt F, Stein A, Kocic B, Rundlöf AK, Fernandes AP, Björnstedt M, and Dobra K

Journal of experimental & clinical cancer research : CR 28:92, 2009 - Who cited this? | PubMed ID: 19563663 | Fulltext

Treatment of lung cancer cells with cytotoxic levels of sodium selenite: effects on the thioredoxin system.

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Selenius M, Fernandes AP, Brodin O, Björnstedt M, and Rundlöf AK

Biochemical pharmacology 75(11):2092, 2008 Jun 1 - Who cited this? | PubMed ID: 18405881 | Fulltext

Molecular and structural basis for redox regulation of beta-actin.

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Lassing I, Schmitzberger F, Björnstedt M, Holmgren A, Nordlund P, Schutt CE, and Lindberg U

Journal of molecular biology 370(2):331-48, 2007 Jul 6 - Who cited this? | PubMed ID: 17521670 | Fulltext

Biliary epithelial cell antibodies link adaptive and innate immune responses in primary sclerosing cholangitis.

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Karrar A, Broomé U, Södergren T, Jaksch M, Bergquist A, Björnstedt M, and Sumitran-Holgersson S

Gastroenterology 132(4):1504-14, 2007 Apr - Who cited this? | PubMed ID: 17408653 | Fulltext

Increased expression of specific thioredoxin family proteins; a pilot immunohistochemical study on human hepatocellular carcinoma.

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Cunnea P, Fernandes AP, Capitanio A, Eken S, Spyrou G, and Björnstedt M

International journal of immunopathology and pharmacology 20(1):17 - Who cited this? | PubMed ID: 17346424 | Fulltext

Quantification of alternative mRNA species and identification of thioredoxin reductase 1 isoforms in human tumor cells.

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Rundlöf AK, Fernandes AP, Selenius M, Babic M, Shariatgorji M, Nilsonne G, Ilag LL, Dobra K, and Björnstedt M

Differentiation; research in biological diversity 75(2):123-32, 2007 Feb - Who cited this? | PubMed ID: 17316382 | Fulltext

Curative bone marrow transplantation in erythropoietic protoporphyria after reversal of severe cholestasis.

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Wahlin S, Aschan J, Björnstedt M, Broomé U, and Harper P

Journal of hepatology 46(1):174-9, 2007 Jan - Who cited this? | PubMed ID: 17112627 | Fulltext

Selenite induces apoptosis in sarcomatoid malignant mesothelioma cells through oxidative stress.

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Nilsonne G, Sun X, Nyström C, Rundlöf AK, Potamitou Fernandes A, Björnstedt M, and Dobra K

Free radical biology & medicine 41(6):874-85, 2006 Sep 15 - Who cited this? | PubMed ID: 16934670 | Fulltext

Adriamycin cytotoxicity may stimulate growth of hepatocellular tumours in an experimental model for adjuvant systemic chemotherapy in liver transplantation.

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Rissler P, Söderdahl G, Nordman T, Xia L, Torndal UB, Björnstedt M, Ericzon BG, Olsson JM, and Eriksson LC

Transplant international : official journal of the European Society for Organ Transplantation 18(8):992-1000, 2005 Aug - Who cited this? | PubMed ID: 16008751 | Fulltext

The role of thioredoxin reductase activity in selenium-induced cytotoxicity.

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Madeja Z, Sroka J, Nyström C, Björkhem-Bergman L, Nordman T, Damdimopoulos A, Nalvarte I, Eriksson LC, Spyrou G, Olsson JM, and Björnstedt M

Biochemical pharmacology 69(12):1765-72, 2005 Jun 15 - Who cited this? | PubMed ID: 15935149 | Fulltext

Differential effects of selenite and selenate on human melanocytes, keratinocytes, and melanoma cells.

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Bandura L, Drukala J, Wolnicka-Glubisz A, Björnstedt M, and Korohoda W

Biochemistry and cell biology = Biochimie et biologie cellulaire 83(2):196-211, 2005 Apr - Who cited this? | PubMed ID: 15864328 | Fulltext

Selenium prevents tumor development in a rat model for chemical carcinogenesis.

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Björkhem-Bergman L, Torndal UB, Eken S, Nyström C, Capitanio A, Larsen EH, Björnstedt M, and Eriksson LC

Carcinogenesis 26(1):125-31, 2005 Jan - Who cited this? | PubMed ID: 15459019 | Fulltext

Overexpression of enzymatically active human cytosolic and mitochondrial thioredoxin reductase in HEK-293 cells. Effect on cell growth and differentiation.

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Nalvarte I, Damdimopoulos AE, Nystöm C, Nordman T, Miranda-Vizuete A, Olsson JM, Eriksson L, Björnstedt M, Arnér ES, and Spyrou G

The Journal of biological chemistry 279(52):54510-7, 2004 Dec 24 - Who cited this? | PubMed ID: 15471857 | Fulltext

Mammalian thioredoxin reductase alters cytolytic activity of an antibacterial peptide.

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Björkhem-Bergman L, Jönsson-Videsäter K, Paul C, Björnstedt M, and Andersson M

Peptides 25(11):1849-55, 2004 Nov - Who cited this? | PubMed ID: 15501515 | Fulltext

Selenite-induced apoptosis in doxorubicin-resistant cells and effects on the thioredoxin system.

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Jönsson-Videsäter K, Björkhem-Bergman L, Hossain A, Söderberg A, Eriksson LC, Paul C, Rosén A, and Björnstedt M

Biochemical pharmacology 67(3):513-22, 2004 Feb 1 - Who cited this? | PubMed ID: 15037203 | Fulltext

Extramitochondrial reduction of ubiquinone by flavoenzymes.

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Björnstedt M, Nordman T, and Olsson JM

Methods in enzymology 378:131-8, 2004 - Who cited this? | PubMed ID: 15038962 | Fulltext

The mammalian cytosolic selenoenzyme thioredoxin reductase reduces ubiquinone. A novel mechanism for defense against oxidative stress.

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Xia L, Nordman T, Olsson JM, Damdimopoulos A, Björkhem-Bergman L, Nalvarte I, Eriksson LC, Arnér ES, Spyrou G, and Björnstedt M

The Journal of biological chemistry 278(4):2141-6, 2003 Jan 24 - Who cited this? | PubMed ID: 12435734 | Fulltext

Regeneration of the antioxidant ubiquinol by lipoamide dehydrogenase, thioredoxin reductase and glutathione reductase.

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Nordman T, Xia L, Björkhem-Bergman L, Damdimopoulos A, Nalvarte I, Arnér ES, Spyrou G, Eriksson LC, Björnstedt M, and Olsson JM

BioFactors (Oxford, England) 18(1-4):45-50, 2003 - Who cited this? | PubMed ID: 14695919 | Fulltext

Drug-resistant human lung cancer cells are more sensitive to selenium cytotoxicity. Effects on thioredoxin reductase and glutathione reductase.

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Björkhem-Bergman L, Jönsson K, Eriksson LC, Olsson JM, Lehmann S, Paul C, and Björnstedt M

Biochemical pharmacology 63(10):1875-84, 2002 May 15 - Who cited this? | PubMed ID: 12034372 | Fulltext

Increased levels of cytosolic thioredoxin reductase activity and mRNA in rat liver nodules.

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Björkhem L, Teclebrhan H, Kesen E, Olsson JM, Eriksson LC, and Björnstedt M

Journal of hepatology 35(2):259-64, 2001 Aug - Who cited this? | PubMed ID: 11580149 | Fulltext

Reduction of ubiquinone by lipoamide dehydrogenase. An antioxidant regenerating pathway.

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Xia L, Björnstedt M, Nordman T, Eriksson LC, and Olsson JM

European journal of biochemistry / FEBS 268(5):1486-90, 2001 Mar - Who cited this? | PubMed ID: 11231302 | Fulltext

Upregulation of 9 genes, including that for thioredoxin, during epithelial differentiation of mesothelioma cells.

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Sun X, Dobra K, Björnstedt M, and Hjerpe A

Differentiation; research in biological diversity 66(4-5):181-8, 2000 Dec - Who cited this? | PubMed ID: 11269944 | Fulltext

Ubiquinone is reduced by lipoamide dehydrogenase and this reaction is potently stimulated by zinc.

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Olsson JM, Xia L, Eriksson LC, and Björnstedt M

FEBS letters 448(1):190-2, 1999 Apr 1 - Who cited this? | PubMed ID: 10217438 | Fulltext

Measurements of plasma glutaredoxin and thioredoxin in healthy volunteers and during open-heart surgery.

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Nakamura H, Vaage J, Valen G, Padilla CA, Björnstedt M, and Holmgren A

Free radical biology & medicine 24(7-8):1176-86, 1998 May - Who cited this? | PubMed ID: 9626572 | Fulltext

Selenium and the thioredoxin and glutaredoxin systems.

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Björnstedt M, Kumar S, Björkhem L, Spyrou G, and Holmgren A

Biomedical and environmental sciences : BES 10(2-3):271-9, 1997 Sep - Who cited this? | PubMed ID: 9315320 | Fulltext

Human IgG is substrate for the thioredoxin system: differential cleavage pattern of interchain disulfide bridges in IgG subclasses.

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Magnusson CG, Björnstedt M, and Holmgren A

Molecular immunology 34(10):709-17, 1997 Jul - Who cited this? | PubMed ID: 9430198 | Fulltext

Selenite and selenate inhibit human lymphocyte growth via different mechanisms.

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Spyrou G, Björnstedt M, Skog S, and Holmgren A

Cancer research 56(19):4407-12, 1996 Oct 1 - Who cited this? | PubMed ID: 8813134 | Fulltext

Selenite incubated with NADPH and mammalian thioredoxin reductase yields selenide, which inhibits lipoxygenase and changes the electron spin resonance spectrum of the active site iron.

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Björnstedt M, Odlander B, Kuprin S, Claesson HE, and Holmgren A

Biochemistry 35(26):8511-6, 1996 Jul 2 - Who cited this? | PubMed ID: 8679612 | Fulltext

AP-1 DNA-binding activity is inhibited by selenite and selenodiglutathione.

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Spyrou G, Björnstedt M, Kumar S, and Holmgren A

FEBS letters 368(1):59-63, 1995 Jul 10 - Who cited this? | PubMed ID: 7615089 | Fulltext

Human thioredoxin reductase directly reduces lipid hydroperoxides by NADPH and selenocystine strongly stimulates the reaction via catalytically generated selenols.

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Björnstedt M, Hamberg M, Kumar S, Xue J, and Holmgren A

The Journal of biological chemistry 270(20):11761-4, 1995 May 19 - Who cited this? | PubMed ID: 7744824 | Fulltext

1-Chloro-2,4-dinitrobenzene is an irreversible inhibitor of human thioredoxin reductase. Loss of thioredoxin disulfide reductase activity is accompanied by a large increase in NADPH oxidase activity.

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Arnér ES, Björnstedt M, and Holmgren A

The Journal of biological chemistry 270(8):3479-82, 1995 Feb 24 - Who cited this? | PubMed ID: 7876079 | Fulltext

Thioredoxin and thioredoxin reductase.

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Holmgren A and Björnstedt M

Methods in enzymology 252:199-208, 1995 - Who cited this? | PubMed ID: 7476354 | Fulltext

Selenite and selenodiglutathione: reactions with thioredoxin systems.

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Björnstedt M, Kumar S, and Holmgren A

Methods in enzymology 252:209-19, 1995 - Who cited this? | PubMed ID: 7476355 | Fulltext

The thioredoxin and glutaredoxin systems are efficient electron donors to human plasma glutathione peroxidase.

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Björnstedt M, Xue J, Huang W, Akesson B, and Holmgren A

The Journal of biological chemistry 269(47):29382-4, 1994 Nov 25 - Who cited this? | PubMed ID: 7961915 | Fulltext

Mutagenesis of structural half-cystine residues in human thioredoxin and effects on the regulation of activity by selenodiglutathione.

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Ren X, Björnstedt M, Shen B, Ericson ML, and Holmgren A

Biochemistry 32(37):9701-8, 1993 Sep 21 - Who cited this? | PubMed ID: 8373774 | Fulltext

Selenite is a substrate for calf thymus thioredoxin reductase and thioredoxin and elicits a large non-stoichiometric oxidation of NADPH in the presence of oxygen.

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Kumar S, Björnstedt M, and Holmgren A

European journal of biochemistry / FEBS 207(2):435-39, 1992 Jul 15 - Who cited this? | PubMed ID: 1321713 | Fulltext

Selenodiglutathione is a highly efficient oxidant of reduced thioredoxin and a substrate for mammalian thioredoxin reductase.

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Björnstedt M, Kumar S, and Holmgren A

The Journal of biological chemistry 267(12):8030-4, 1992 Apr 25 - Who cited this? | PubMed ID: 1569062 | Fulltext

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