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Papers authored by Bertino JR

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Cancer research: from folate antagonism to molecular targets.

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Bertino JR

Best practice & research. Clinical haematology 22(4):577-82, 2009 Dec - Who cited this? | PubMed ID: 19959110 | Fulltext

Translational modulation of proteins expressed from bicistronic vectors.

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Mishra PJ, Menon LG, Mishra PJ, Mayer-Kuckuk P, Bertino JR, and Banerjee D

Molecular imaging : official journal of the Society for Molecular Imaging 8(6):305-18, 2009 Dec - Who cited this? | PubMed ID: 20003889 | Fulltext

Heparin and Suramin Alter Plitidepsin Uptake Via Inhibition of GPCR Coupled Signaling.

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Longo-Sorbello GS, Gao H, Mishra PJ, Kamen B, Soto A, Jimeno J, Aracil M, Paz DE Paz MF, Bertino JR, and Banerjee D

Journal of chemotherapy (Florence, Italy) 21(5):550-7, 2009 Nov - Who cited this? | PubMed ID: 19933047 | Fulltext

Species-specific differences in translational regulation of dihydrofolate reductase.

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Hsieh YC, Skacel NE, Bansal N, Scotto KW, Banerjee D, Bertino JR, and Abali EE

Molecular pharmacology 76(4):723-33, 2009 Oct - Who cited this? | PubMed ID: 19570950 | Fulltext

Accelerated R-COP: a pilot study for the treatment of advanced low grade lymphomas that has a high complete response rate.

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Levitt MJ, Gharibo M, Strair R, Schaar D, Rubin A, and Bertino JR

Journal of chemotherapy (Florence, Italy) 21(4):434-8, 2009 Aug - Who cited this? | PubMed ID: 19622463 | Fulltext

MicroRNA polymorphisms: the future of pharmacogenomics, molecular epidemiology and individualized medicine.

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Mishra PJ and Bertino JR

Pharmacogenomics 10(3):399-416, 2009 Mar - Who cited this? | PubMed ID: 19290790 | Fulltext

Retinoblastoma tumor suppressor gene expression determines the response to sequential flavopiridol and Doxorubicin treatment in small-cell lung carcinoma.

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Budak-Alpdogan T, Chen B, Warrier A, Medina DJ, Moore D, and Bertino JR

Clinical cancer research : an official journal of the American Association for Cancer Research 15(4):1232-40, 2009 Feb 15 - Who cited this? | PubMed ID: 19174488 | Fulltext

Molecular targets for epigenetic therapy of cancer.

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Humeniuk R, Mishra PJ, Bertino JR, and Banerjee D

Current pharmaceutical biotechnology 10(2):161-5, 2009 Feb - Who cited this? | PubMed ID: 19199948 | Fulltext

Chemoprotection by transfer of resistance genes.

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Budak-Alpdogan T and Bertino JR

Methods in molecular biology (Clifton, N.J.) 542:661-704, 2009 - Who cited this? | PubMed ID: 19565927 | Fulltext

MiR-24 Tumor Suppressor Activity Is Regulated Independent of p53 and through a Target Site Polymorphism.

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Mishra PJ, Song B, Mishra PJ, Wang Y, Humeniuk R, Banerjee D, Merlino G, Ju J, and Bertino JR

PLoS ONE 4(12):e8445, 2009 - Who cited this? | PubMed ID: 20041160 | Fulltext

Implantable pump for long-term chemotherapy administration via the hepatic artery: has it fulfilled its promise?.

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Bertino JR

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 26(28):4528-9, 2008 Oct 1 - Who cited this? | PubMed ID: 18824703 | Fulltext

Transfer of drug resistance genes into hematopoietic stem cells for marrow protection.

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Bertino JR

The oncologist 13(10):1036-42, 2008 Oct - Who cited this? | PubMed ID: 18952565 | Fulltext

Potential regional differences for the tolerability profiles of fluoropyrimidines.

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Haller DG, Cassidy J, Clarke SJ, Cunningham D, Van Cutsem E, Hoff PM, Rothenberg ML, Saltz LB, Schmoll HJ, Allegra C, Bertino JR, Douillard JY, Gustavsson BG, Milano G, O'Connell M, Rustum Y,

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Journal of clinical oncology : official journal of the American Society of Clinical Oncology 26(13):2118-23, 2008 May 1 - Who cited this? | PubMed ID: 18445840 | Fulltext

MiRSNPs or MiR-polymorphisms, new players in microRNA mediated regulation of the cell: Introducing microRNA pharmacogenomics.

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Mishra PJ, Mishra PJ, Banerjee D, and Bertino JR

Cell cycle (Georgetown, Tex.) 7(7):853, 2008 Apr - Who cited this? | PubMed ID: 18414050 | Fulltext

Quantitative correlation between promoter methylation and messenger RNA levels of the reduced folate carrier.

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Yang R, Li WW, Hoang BH, Kim H, Banerjee D, Kheradpour A, Healey JH, Meyers PA, Bertino JR, and Gorlick R

BMC cancer 8:124, 2008 - Who cited this? | PubMed ID: 18452618 | Fulltext

Aplidin synergizes with cytosine arabinoside: functional relevance of mitochondria in Aplidin-induced cytotoxicity.

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Humeniuk R, Menon LG, Mishra PJ, Saydam G, Longo-Sorbello GS, Elisseyeff Y, Lewis LD, Aracil M, Jimeno J, Bertino JR, and Banerjee D

Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 21(12):2399, 2007 Dec - Who cited this? | PubMed ID: 17713546 | Fulltext

Pharmacogenomics of microRNA: a miRSNP towards individualized therapy.

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Bertino JR, Banerjee D, and Mishra PJ

Pharmacogenomics 8(12):1625-7, 2007 Dec - Who cited this? | PubMed ID: 18085993 | Fulltext

Maintaining the dose intensity of ICE chemotherapy with a thrombopoietic agent, PEG-rHuMGDF, may confer a survival advantage in relapsed and refractory aggressive non-Hodgkin lymphoma.

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Moskowitz CH, Hamlin PA, Gabrilove J, Bertino JR, Portlock CS, Straus DJ, Gencarelli AN, Nimer SD, and Zelenetz AD

Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 18(11):1842, 2007 Nov - Who cited this? | PubMed ID: 17872903 | Fulltext

A miR-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads to methotrexate resistance.

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Mishra PJ, Humeniuk R, Mishra PJ, Longo-Sorbello GS, Banerjee D, and Bertino JR

Proceedings of the National Academy of Sciences of the United States of America 104(33):13513-8, 2007 Aug 14 - Who cited this? | PubMed ID: 17686970 | Fulltext

Role of pemetrexed in non-small cell lung cancer.

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Longo-Sorbello GS, Chen B, Budak-Alpdogan T, and Bertino JR

Cancer investigation 25(1):59-66, 2007 Feb - Who cited this? | PubMed ID: 17364559 | Fulltext

EGFP fluorescence as an indicator of cancer cells response to methotrexate.

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Dabrowska M, Hendrikx PJ, Skierski J, Malinowska M, Bertino JR, and Rode W

European journal of pharmacology 555(2-3):93-9, 2007 Jan 26 - Who cited this? | PubMed ID: 17141212 | Fulltext

E2F-1 overexpression in U2OS cells increases cyclin B1 levels and cdc2 kinase activity and sensitizes cells to antimitotic agents.

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Russo AJ, Magro PG, Hu Z, Li WW, Peters R, Mandola J, Banerjee D, and Bertino JR

Cancer research 66(14):7253, 2006 Jul 15 - Who cited this? | PubMed ID: 16849574 | Fulltext

Molecular imaging reveals skeletal engraftment sites of transplanted bone marrow cells.

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Mayer-Kuckuk P, Doubrovin M, Bidaut L, Budak-Alpdogan T, Cai S, Hubbard V, Alpdogan O, van den Brink M, Bertino JR, Blasberg RG, Banerjee D, and Gelovani J

Cell transplantation 15(1):75-82, 2006 - Who cited this? | PubMed ID: 16700332 | Fulltext

Hematopoietic stem cell gene therapy with drug resistance genes: an update.

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Budak-Alpdogan T, Banerjee D, and Bertino JR

Cancer gene therapy 12(11):849-63, 2005 Nov - Who cited this? | PubMed ID: 16037821 | Fulltext

High-resolution imaging of bone precursor cells within the intact bone marrow cavity of living mice.

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Mayer-Kuckuk P, Gade TP, Buchanan IM, Doubrovin M, Ageyeva L, Bertino JR, Boskey AL, Blasberg RG, Koutcher JA, and Banerjee D

Molecular therapy : the journal of the American Society of Gene Therapy 12(1):33-41, 2005 Jul - Who cited this? | PubMed ID: 15963918 | Fulltext

Identification of amino acids required for the functional up-regulation of human dihydrofolate reductase protein in response to antifolate Treatment.

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Skacel N, Menon LG, Mishra PJ, Peters R, Banerjee D, Bertino JR, and Abali EE

The Journal of biological chemistry 280(24):22721-31, 2005 Jun 17 - Who cited this? | PubMed ID: 15817466 | Fulltext

Protection of hematopoietic stem cells from pemetrexed toxicity by retroviral gene transfer with a mutant dihydrofolate reductase-mutant thymidylate synthase fusion gene.

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Capiaux GM, Budak-Alpdogan T, Alpdogan O, Bornmann W, Takebe N, Banerjee D, Maley F, and Bertino JR

Cancer gene therapy 11(12):767-73, 2004 Dec - Who cited this? | PubMed ID: 15359285 | Fulltext

The NHL-15 protocol for aggressive non-Hodgkin's lymphomas: a sequential dose-dense, dose-intense regimen of doxorubicin, vincristine and high-dose cyclophosphamide.

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Portlock CS, Qin J, Schaindlin P, Roistacher N, Myers J, Filippa D, Louie D, Zelenetz AD, O'Brien JP, Moskowitz C, Norton L, Yahalom J, Straus DJ, and Bertino JR

Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 15(10):1495, 2004 Oct - Who cited this? | PubMed ID: 15367410 | Fulltext

Methotrexate and cytarabine inhibit progression of human lymphoma in NOD/SCID mice carrying a mutant dihydrofolate reductase and cytidine deaminase fusion gene.

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Budak-Alpdogan T, Alpdogan O, Banerjee D, Wang E, Moore MA, and Bertino JR

Molecular therapy : the journal of the American Society of Gene Therapy 10(3):574-84, 2004 Sep - Who cited this? | PubMed ID: 15336657 | Fulltext

p14ARF expression increases dihydrofolate reductase degradation and paradoxically results in resistance to folate antagonists in cells with nonfunctional p53.

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Magro PG, Russo AJ, Li WW, Banerjee D, and Bertino JR

Cancer research 64(12):4338-45, 2004 Jun 15 - Who cited this? | PubMed ID: 15205349 | Fulltext

Specific tumour localisation of a huA33 antibody--carboxypeptidase A conjugate and activation of methotrexate-phenylalanine.

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Deckert PM, Bornmann WG, Ritter G, Williams C, Franke J, Keilholz U, Thiel E, Old LJ, Bertino JR, and Welt S

International journal of oncology 24(5):1289-95, 2004 May - Who cited this? | PubMed ID: 15067353 | Fulltext

Role of reporter gene imaging in molecular and cellular biology.

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Mayer-Kuckuk P, Menon LG, Blasberg RG, Bertino JR, and Banerjee D

Biological chemistry 385(5):353-61, 2004 May - Who cited this? | PubMed ID: 15195994 | Fulltext

Thymidylate synthase as an oncogene?.

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Bertino JR and Banerjee D

Cancer cell 5(4):301-2, 2004 Apr - Who cited this? | PubMed ID: 15093534 | Fulltext

Overexpression of E2F-1 in lung and liver metastases of human colon cancer is associated with gene amplification.

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Iwamoto M, Banerjee D, Menon LG, Jurkiewicz A, Rao PH, Kemeny NE, Fong Y, Jhanwar SC, Gorlick R, and Bertino JR

Cancer biology & therapy 3(4):395-9, 2004 Apr - Who cited this? | PubMed ID: 14726656 | Fulltext

Status of methylthioadenosine phosphorylase and its impact on cellular response to L-alanosine and methylmercaptopurine riboside in human soft tissue sarcoma cells.

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Li W, Su D, Mizobuchi H, Martin DS, Gu B, Gorlick R, Cole P, and Bertino JR

Oncology research 14(7-8):373-9, 2004 - Who cited this? | PubMed ID: 15301428 | Fulltext

Imaging of dihydrofolate reductase fusion gene expression in xenografts of human liver metastases of colorectal cancer in living rats.

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Mayer-Kuckuk P, Doubrovin M, Gusani NJ, Gade T, Balatoni J, Akhurst T, Finn R, Fong Y, Koutcher JA, Larson S, Blasberg R, Tjuvajev JG, Bertino JR, and Banerjee D

European journal of nuclear medicine and molecular imaging 30(9):1281-91, 2003 Sep - Who cited this? | PubMed ID: 12664136 | Fulltext

Reduced folate carrier and dihydrofolate reductase expression in acute lymphocytic leukemia may predict outcome: a Children's Cancer Group Study.

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Levy AS, Sather HN, Steinherz PG, Sowers R, La M, Moscow JA, Gaynon PS, Uckun FM, Bertino JR, Gorlick R, and Children's Cancer Group Study

Journal of pediatric hematology/oncology : official journal of the American Society of Pediatric Hematology/Oncology 25(9):688-95, 2003 Sep - Who cited this? | PubMed ID: 12972803 | Fulltext

mRNA expression levels of E2F transcription factors correlate with dihydrofolate reductase, reduced folate carrier, and thymidylate synthase mRNA expression in osteosarcoma.

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Sowers R, Toguchida J, Qin J, Meyers PA, Healey JH, Huvos A, Banerjee D, Bertino JR, and Gorlick R

Molecular cancer therapeutics 2(6):535, 2003 Jun - Who cited this? | PubMed ID: 12813132 | Fulltext

Is the measurement of thymidylate synthase to determine suitability for treatment with 5-fluoropyrimidines ready for prime time?.

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Bertino JR and Banerjee D

Clinical cancer research : an official journal of the American Association for Cancer Research 9(4):1235-9, 2003 Apr - Who cited this? | PubMed ID: 12684389 | Fulltext

A33scFv-cytosine deaminase: a recombinant protein construct for antibody-directed enzyme-prodrug therapy.

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Deckert PM, Renner C, Cohen LS, Jungbluth A, Ritter G, Bertino JR, Old LJ, and Welt S

British journal of cancer 88(6):937-9, 2003 Mar 24 - Who cited this? | PubMed ID: 12644833 | Fulltext

Retroviral transduction of a mutant dihydrofolate reductase-thymidylate synthase fusion gene into murine marrow cells confers resistance to both methotrexate and 5-fluorouracil.

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Capiaux GM, Budak-Alpdogan T, Takebe N, Mayer-Kuckuk P, Banerjee D, Maley F, and Bertino JR

Human gene therapy 14(5):435-46, 2003 Mar 20 - Who cited this? | PubMed ID: 12691609 | Fulltext

Sequence alterations in the reduced folate carrier are observed in osteosarcoma tumor samples.

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Yang R, Sowers R, Mazza B, Healey JH, Huvos A, Grier H, Bernstein M, Beardsley GP, Krailo MD, Devidas M, Bertino JR, Meyers PA, and Gorlick R

Clinical cancer research : an official journal of the American Association for Cancer Research 9(2):837-44, 2003 Feb - Who cited this? | PubMed ID: 12576457 | Fulltext

Sequence-dependent synergistic cytotoxicity of ecteinascidin-743 and paclitaxel in human breast cancer cell lines in vitro and in vivo.

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Takahashi N, Li W, Banerjee D, Guan Y, Wada-Takahashi Y, Brennan MF, Chou TC, Scotto KW, and Bertino JR

Cancer research 62(23):6909-15, 2002 Dec 1 - Who cited this? | PubMed ID: 12460906 | Fulltext

Fas-mediated signaling enhances sensitivity of human soft tissue sarcoma cells to anticancer drugs by activation of p38 kinase.

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Li W and Bertino JR

Molecular cancer therapeutics 1(14):1343-8, 2002 Dec - Who cited this? | PubMed ID: 12516968 | Fulltext

Characterization of potent inhibitors of the Bcr-Abl and the c-kit receptor tyrosine kinases.

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Wisniewski D, Lambek CL, Liu C, Strife A, Veach DR, Nagar B, Young MA, Schindler T, Bornmann WG, Bertino JR, Kuriyan J, and Clarkson B

Cancer research 62(15):4244, 2002 Aug 1 - Who cited this? | PubMed ID: 12154026 | Fulltext

Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase.

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Banerjee D, Mayer-Kuckuk P, Capiaux G, Budak-Alpdogan T, Gorlick R, and Bertino JR

Biochimica et biophysica acta 1587(2-3):164-73, 2002 Jul 18 - Who cited this? | PubMed ID: 12084458 | Fulltext

Molecular therapies for colorectal cancer metastatic to the liver.

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Mayer-Kuckuk P, Banerjee D, Kemeny N, Fong Y, and Bertino JR

Molecular therapy : the journal of the American Society of Gene Therapy 5(5 Pt 1):492-500, 2002 May - Who cited this? | PubMed ID: 11991739 | Fulltext

Cells exposed to antifolates show increased cellular levels of proteins fused to dihydrofolate reductase: a method to modulate gene expression.

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Mayer-Kuckuk P, Banerjee D, Malhotra S, Doubrovin M, Iwamoto M, Akhurst T, Balatoni J, Bornmann W, Finn R, Larson S, Fong Y, Gelovani Tjuvajev J, Blasberg R, and Bertino JR

Proceedings of the National Academy of Sciences of the United States of America 99(6):3400-5, 2002 Mar 19 - Who cited this? | PubMed ID: 11891321 | Fulltext

Methotrexate selection of long-term culture initiating cells following transduction of CD34(+) cells with a retrovirus containing a mutated human dihydrofolate reductase gene.

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Takebe N, Xu LC, MacKenzie KL, Bertino JR, and Moore MA

Cancer gene therapy 9(3):308-20, 2002 Mar - Who cited this? | PubMed ID: 11896448 | Fulltext

Methylthioadenosine phosphorylase gene deletions are common in osteosarcoma.

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García-Castellano JM, Villanueva A, Healey JH, Sowers R, Cordon-Cardo C, Huvos A, Bertino JR, Meyers P, and Gorlick R

Clinical cancer research : an official journal of the American Association for Cancer Research 8(3):782-7, 2002 Mar - Who cited this? | PubMed ID: 11895909 | Fulltext

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