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Papers authored by Beinborn M

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TGF-{beta} regulates T-cell neurokinin-1 receptor internalization and function.

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Beinborn M, Blum A, Hang L, Setiawan T, Schroeder JC, Stoyanoff K, Leung J, and Weinstock JV

Proceedings of the National Academy of Sciences of the United States of America 107(9):4293-8, 2010 Mar 2 - Who cited this? | PubMed ID: 20160079 | Fulltext

Pharmacological characterization of human incretin receptor missense variants.

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Fortin JP, Schroeder JC, Zhu Y, Beinborn M, and Kopin AS

The Journal of pharmacology and experimental therapeutics 332(1):274-80, 2010 Jan - Who cited this? | PubMed ID: 19841474 | Fulltext

Neurogenin 3-specific dipeptidyl peptidase-2 deficiency causes impaired glucose tolerance, insulin resistance, and visceral obesity.

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Danilova OV, Tai AK, Mele DA, Beinborn M, Leiter AB, Greenberg AS, Perfield JW, Defuria J, Singru PS, Lechan RM, and Huber BT

Endocrinology 150(12):5240-8, 2009 Dec - Who cited this? | PubMed ID: 19819973 | Fulltext

Membrane-tethered ligands are effective probes for exploring class B1 G protein-coupled receptor function.

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Fortin JP, Zhu Y, Choi C, Beinborn M, Nitabach MN, and Kopin AS

Proceedings of the National Academy of Sciences of the United States of America 106(19):8049-54, 2009 May 12 - Who cited this? | PubMed ID: 19416829 | Fulltext

Facile synthesis of glucagon-like peptide-1 (GLP-1) mimetics.

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Han SY, Beinborn M, and Ahn JM

Advances in experimental medicine and biology 611:119-20, 2009 - Who cited this? | PubMed ID: 19400120 | Fulltext

Rational design of peptidomimetics for class B GPCRs: potent non-peptide GLP-1 receptor agonists.

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Ahn JM, Han SY, Murage E, and Beinborn M

Advances in experimental medicine and biology 611:125-6, 2009 - Who cited this? | PubMed ID: 19400122 | Fulltext

Seeking for alpha-helical propensity in a receptor-bound conformation of glucagon-like peptide-1.

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Murage E, Beinborn M, and Ahn JM

Advances in experimental medicine and biology 611:289-90, 2009 - Who cited this? | PubMed ID: 19400196 | Fulltext

Search for alpha-helical propensity in the receptor-bound conformation of glucagon-like peptide-1.

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Murage EN, Schroeder JC, Beinborn M, and Ahn JM

Bioorganic & medicinal chemistry 16(23):10106-12, 2008 Dec 1 - Who cited this? | PubMed ID: 18952440 | Fulltext

Influence of Selective Fluorination on the Biological Activity and Proteolytic Stability of Glucagon-like Peptide-1.

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Meng H, Krishnaji ST, Beinborn M, and Kumar K

Journal of medicinal chemistry 51(22):7303-7, 2008 Nov 27 - Who cited this? | PubMed ID: 18950150 | Fulltext

Pharmacological analysis of human d1 and d2 dopamine receptor missense variants.

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Al-Fulaij MA, Ren Y, Beinborn M, and Kopin AS

Journal of molecular neuroscience : MN 34(3):211-23, 2008 - Who cited this? | PubMed ID: 18210231 | Fulltext

Four missense mutations in the ghrelin receptor result in distinct pharmacological abnormalities.

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Liu G, Fortin JP, Beinborn M, and Kopin AS

The Journal of pharmacology and experimental therapeutics 322(3):1036, 2007 Sep - Who cited this? | PubMed ID: 17596538 | Fulltext

Identification of amino acid determinants of dopamine 2 receptor synthetic agonist function.

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Al-Fulaij MA, Ren Y, Beinborn M, and Kopin AS

The Journal of pharmacology and experimental therapeutics 321(1):298-307, 2007 Apr - Who cited this? | PubMed ID: 17204745 | Fulltext

Point mutations in either subunit of the GABAB receptor confer constitutive activity to the heterodimer.

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Mukherjee RS, McBride EW, Beinborn M, Dunlap K, and Kopin AS

Molecular pharmacology 70(4):1406, 2006 Oct - Who cited this? | PubMed ID: 16847143 | Fulltext

Class B GPCRs: a hidden agonist within?.

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Beinborn M

Molecular pharmacology 70(1):1, 2006 Jul - Who cited this? | PubMed ID: 16632645 | Fulltext

A human glucagon-like peptide-1 receptor polymorphism results in reduced agonist responsiveness.

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Beinborn M, Worrall CI, McBride EW, and Kopin AS

Regulatory peptides 130(1-2):1-6, 2005 Aug 15 - Who cited this? | PubMed ID: 15975668 | Fulltext

Basal receptor activation by locally produced glucagon-like peptide-1 contributes to maintaining beta-cell function.

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Masur K, Tibaduiza EC, Chen C, Ligon B, and Beinborn M

Molecular endocrinology (Baltimore, Md.) 19(5):1373-82, 2005 May - Who cited this? | PubMed ID: 15677711 | Fulltext

Ménétrier's disease in a patient with Helicobacter pylori infection is linked to elevated glucagon-like peptide-2 activity.

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Watanabe K, Beinborn M, Nagamatsu S, Ishida H, and Takahashi S

Scandinavian journal of gastroenterology 40(4):477-81, 2005 Apr - Who cited this? | PubMed ID: 16028444 | Fulltext

Interleukin-1 upregulates anaphylatoxin receptors on mononuclear cells.

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Takabayashi T, Shimizu S, Clark BD, Beinborn M, Burke JF, and Gelfand JA

Surgery 135(5):544-54, 2004 May - Who cited this? | PubMed ID: 15118592 | Fulltext

Ligand function at constitutively active receptor mutants is affected by two distinct yet interacting mechanisms.

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Beinborn M, Ren Y, Bläker M, Chen C, and Kopin AS

Molecular pharmacology 65(3):753-60, 2004 Mar - Who cited this? | PubMed ID: 14978254 | Fulltext

Established theory of radiation-induced decay is not generalizable to Bolton-Hunter labeled peptides.

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Doran AC, Wan YP, Kopin AS, and Beinborn M

Biochemical pharmacology 65(9):1515-20, 2003 May 1 - Who cited this? | PubMed ID: 12732364 | Fulltext

Identification of a series of CCK-2 receptor nonpeptide agonists: sensitivity to stereochemistry and a receptor point mutation.

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Kopin AS, McBride EW, Chen C, Freidinger RM, Chen D, Zhao CM, and Beinborn M

Proceedings of the National Academy of Sciences of the United States of America 100(9):5525-30, 2003 Apr 29 - Who cited this? | PubMed ID: 12697901 | Fulltext

Conserved cholecystokinin receptor transmembrane domain IV amino acids confer peptide affinity.

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Ren Y, Bläker M, Seshadri L, McBride EW, Beinborn M, and Kopin AS

Journal of molecular neuroscience : MN 20(2):115-24, 2003 Apr - Who cited this? | PubMed ID: 12794305 | Fulltext

A Drosophila dopamine 2-like receptor: Molecular characterization and identification of multiple alternatively spliced variants.

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Hearn MG, Ren Y, McBride EW, Reveillaud I, Beinborn M, and Kopin AS

Proceedings of the National Academy of Sciences of the United States of America 99(22):14554, 2002 Oct 29 - Who cited this? | PubMed ID: 12391323 | Fulltext

A small molecule ligand of the glucagon-like peptide 1 receptor targets its amino-terminal hormone binding domain.

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Tibaduiza EC, Chen C, and Beinborn M

The Journal of biological chemistry 276(41):37787-93, 2001 Oct 12 - Who cited this? | PubMed ID: 11498540 | Fulltext

Inhibition of morphine tolerance development by a substance P-opioid peptide chimera.

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Foran SE, Carr DB, Lipkowski AW, Maszczynska I, Marchand JE, Misicka A, Beinborn M, Kopin AS, and Kream RM

The Journal of pharmacology and experimental therapeutics 295(3):1142-8, 2000 Dec - Who cited this? | PubMed ID: 11082451 | Fulltext

Investigation of gastroprotective compounds at subcellular level in isolated gastric mucosal cells.

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Nagy L, Morales RE, Beinborn M, Vattay P, and Szabo S

American journal of physiology. Gastrointestinal and liver physiology 279(6):G1201-8, 2000 Dec - Who cited this? | PubMed ID: 11093942 | Fulltext

CCK receptor polymorphisms: an illustration of emerging themes in pharmacogenomics.

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Kopin AS, McBride EW, Schaffer K, and Beinborn M

Trends in pharmacological sciences 21(9):346-53, 2000 Sep - Who cited this? | PubMed ID: 10973088 | Fulltext

CCK-B/Gastrin receptor transmembrane domain mutations selectively alter synthetic agonist efficacy without affecting the activity of endogenous peptides.

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Bläker M, Ren Y, Seshadri L, McBride EW, Beinborn M, and Kopin AS

Molecular pharmacology 58(2):399-406, 2000 Aug - Who cited this? | PubMed ID: 10908308 | Fulltext

A substance P-opioid chimeric peptide as a unique nontolerance-forming analgesic.

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Foran SE, Carr DB, Lipkowski AW, Maszczynska I, Marchand JE, Misicka A, Beinborn M, Kopin AS, and Kream RM

Proceedings of the National Academy of Sciences of the United States of America 97(13):7621-6, 2000 Jun 20 - Who cited this? | PubMed ID: 10852965 | Fulltext

The cholecystokinin-A receptor mediates inhibition of food intake yet is not essential for the maintenance of body weight.

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Kopin AS, Mathes WF, McBride EW, Nguyen M, Al-Haider W, Schmitz F, Bonner-Weir S, Kanarek R, and Beinborn M

The Journal of clinical investigation 103(3):383-91, 1999 Feb - Who cited this? | PubMed ID: 9927499 | Fulltext

Mutations within the cholecystokinin-B/gastrin receptor ligand 'pocket' interconvert the functions of nonpeptide agonists and antagonists.

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Bläker M, Ren Y, Gordon MC, Hsu JE, Beinborn M, and Kopin AS

Molecular pharmacology 54(5):857-63, 1998 Nov - Who cited this? | PubMed ID: 9804620 | Fulltext

Interspecies polymorphisms confer constitutive activity to the Mastomys cholecystokinin-B/gastrin receptor.

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Schaffer K, McBride EW, Beinborn M, and Kopin AS

The Journal of biological chemistry 273(44):28779-84, 1998 Oct 30 - Who cited this? | PubMed ID: 9786876 | Fulltext

Minor modifications of a cholecystokinin-B/gastrin receptor non-peptide antagonist confer a broad spectrum of functional properties.

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Beinborn M, Quinn SM, and Kopin AS

The Journal of biological chemistry 273(23):14146-51, 1998 Jun 5 - Who cited this? | PubMed ID: 9603914 | Fulltext

Small synthetic ligands of the cholecystokinin-B/gastrin receptor can mimic the function of endogenous peptide hormones.

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Beinborn M, Chen C, DeMeo L, McBride EW, and Kopin AS

The Yale journal of biology and medicine 71(3-4):337-46, 1998 - Who cited this? | PubMed ID: 10461364 | Fulltext

Abnormal gastric morphology and function in CCK-B/gastrin receptor-deficient mice.

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Rindi G, Langhans N, Rehfeld JF, Beinborn M, and Kopin AS

The Yale journal of biology and medicine 71(3-4):347-54, 1998 - Who cited this? | PubMed ID: 10461365 | Fulltext

Inter- and intraspecies polymorphisms in the cholecystokinin-B/gastrin receptor alter drug efficacy.

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Kopin AS, McBride EW, Gordon MC, Quinn SM, and Beinborn M

Proceedings of the National Academy of Sciences of the United States of America 94(20):11043-8, 1997 Sep 30 - Who cited this? | PubMed ID: 9380756 | Fulltext

Abnormal gastric histology and decreased acid production in cholecystokinin-B/gastrin receptor-deficient mice.

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Langhans N, Rindi G, Chiu M, Rehfeld JF, Ardman B, Beinborn M, and Kopin AS

Gastroenterology 112(1):280-6, 1997 Jan - Who cited this? | PubMed ID: 8978369 | Fulltext

Identification of cholecystokinin-B/gastrin receptor domains that confer high gastrin affinity: utilization of a novel Xenopus laevis cholecystokinin receptor.

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Schmitz F, Pratt DS, Wu MJ, Kolakowski LF, Beinborn M, and Kopin AS

Molecular pharmacology 50(2):436-41, 1996 Aug - Who cited this? | PubMed ID: 8700154 | Fulltext

Characterization of CCKA receptor mediated pepsinogen secretion in porcine chief cells.

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Meyer G, Beinborn M, and Sewing KF

Pharmacology 53(1):48-59, 1996 Jul - Who cited this? | PubMed ID: 8875601 | Fulltext

Purinoceptor P2U identification and function in human intrahepatic biliary epithelial cell lines.

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Wolkoff LI, Perrone RD, Grubman SA, Lee DW, Soltoff SP, Rogers LC, Beinborn M, Fang SL, Cheng SH, and Jefferson DM

Cell calcium 17(5):375-83, 1995 May - Who cited this? | PubMed ID: 7553790 | Fulltext

The role of the cholecystokinin-B/gastrin receptor transmembrane domains in determining affinity for subtype-selective ligands.

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Kopin AS, McBride EW, Quinn SM, Kolakowski LF, and Beinborn M

The Journal of biological chemistry 270(10):5019-23, 1995 Mar 10 - Who cited this? | PubMed ID: 7890609 | Fulltext

The effect of recombinant cytokines on [14C]-aminopyrine accumulation by isolated canine parietal cells.

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Nompleggi DJ, Beinborn M, Roy A, and Wolfe MM

The Journal of pharmacology and experimental therapeutics 270(2):440-5, 1994 Aug - Who cited this? | PubMed ID: 7520939 | Fulltext

The CCK-B/gastrin receptor. Identification of amino acids that determine nonpeptide antagonist affinity.

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Kopin AS, Beinborn M, Lee YM, McBride EW, and Quinn SM

Annals of the New York Academy of Sciences 713:67-78, 1994 Mar 23 - Who cited this? | PubMed ID: 8185216 | Fulltext

Phospholipid synthesis in isolated porcine gastric mucous cells.

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Bernhard W, Linck M, Beinborn M, Schünemann P, and Sewing KF

Pharmacology 48(3):176-86, 1994 Mar - Who cited this? | PubMed ID: 8153145 | Fulltext

Isolation, identification and quantitative evaluation of specific cell types from the mammalian gastric mucosa.

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Beinborn M, Giebel J, Linck M, Cetin Y, Schwenk M, and Sewing KF

Cell and tissue research 274(2):229-40, 1993 Nov - Who cited this? | PubMed ID: 7505719 | Fulltext

The human brain cholecystokinin-B/gastrin receptor. Cloning and characterization.

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Lee YM, Beinborn M, McBride EW, Lu M, Kolakowski LF, and Kopin AS

The Journal of biological chemistry 268(11):8164-9, 1993 Apr 15 - Who cited this? | PubMed ID: 7681836 | Fulltext

A single amino acid of the cholecystokinin-B/gastrin receptor determines specificity for non-peptide antagonists.

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Beinborn M, Lee YM, McBride EW, Quinn SM, and Kopin AS

Nature 362(6418):348-50, 1993 Mar 25 - Who cited this? | PubMed ID: 8455720 | Fulltext

Gastric prostaglandin E2 receptors are the common antisecretory target of mucosal prostanoids.

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Hennies S, Beinborn M, and Sewing KF

European journal of pharmacology 218(2-3):303-10, 1992 Aug 6 - Who cited this? | PubMed ID: 1385167 | Fulltext

Expression cloning and characterization of the canine parietal cell gastrin receptor.

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Kopin AS, Lee YM, McBride EW, Miller LJ, Lu M, Lin HY, Kolakowski LF, and Beinborn M

Proceedings of the National Academy of Sciences of the United States of America 89(8):3605-9, 1992 Apr 15 - Who cited this? | PubMed ID: 1373504 | Fulltext

Subcellular localization of prostaglandin E2 receptors in the gastric mucosa.

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Beinborn M, Netz S, Staar U, and Sewing KF

Acta physiologica Hungarica 80(1-4):159-73, 1992 - Who cited this? | PubMed ID: 1345183 | Fulltext

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