Papers authored by Begthel H

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The ets-domain transcription factor spdef promotes maturation of goblet and paneth cells in the intestinal epithelium.
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Gregorieff A, Stange DE, Kujala P, Begthel H, van den Born M, Korving J, Peters PJ, and Clevers H
Gastroenterology 137(4):1333-1345.e3, 2009 Oct - Who cited this? | PubMed ID: 19549527 | Fulltext
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Prominin-1/CD133 Marks Stem Cells and Early Progenitors in Mouse Small Intestine.
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Snippert HJ, van Es JH, van den Born M, Begthel H, Stange DE, Barker N, and Clevers H
Gastroenterology 136(7):2187-2194.e1, 2009 Jun - Who cited this? | PubMed ID: 19324043 | Fulltext
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MafB oncoprotein detected by immunohistochemistry as a highly sensitive and specific marker for the prognostic unfavorable t(14;20) (q32;q12) in multiple myeloma patients.
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Stralen E, Leguit RJ, Begthel H, Michaux L, Buijs A, Lemmens H, Scheiff JM, Doyen C, Pierre P, Forget F, Clevers HC, and Bast B
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 23(4):801-3, 2009 Apr - Who cited this? | PubMed ID: 18830254 | Fulltext
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Mst4 and Ezrin induce brush borders downstream of the Lkb1/Strad/Mo25 polarization complex.
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ten Klooster JP, Jansen M, Yuan J, Oorschot V, Begthel H, Di Giacomo V, Colland F, de Koning J, Maurice MM, Hornbeck P, and Clevers H
Developmental cell 16(4):551-62, 2009 Apr - Who cited this? | PubMed ID: 19386264 | Fulltext
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Transcription factor achaete scute-like 2 controls intestinal stem cell fate.
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van der Flier LG, van Gijn ME, Hatzis P, Kujala P, Haegebarth A, Stange DE, Begthel H, van den Born M, Guryev V, Oving I, van Es JH, Barker N, Peters PJ, van de Wetering M, and Clevers H
Cell 136(5):903-12, 2009 Mar 6 - Who cited this? | PubMed ID: 19269367 | Fulltext
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Crypt stem cells as the cells-of-origin of intestinal cancer.
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Barker N, Ridgway RA, van Es JH, van de Wetering M, Begthel H, van den Born M, Danenberg E, Clarke AR, Sansom OJ, and Clevers H
Nature 457(7229):608-11, 2009 Jan 29 - Who cited this? | PubMed ID: 19092804 | Fulltext
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Identification of stem cells in small intestine and colon by marker gene Lgr5.
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Barker N, van Es JH, Kuipers J, Kujala P, van den Born M, Cozijnsen M, Haegebarth A, Korving J, Begthel H, Peters PJ, and Clevers H
Nature 449(7165):1003-7, 2007 Oct 25 - Who cited this? | PubMed ID: 17934449 | Fulltext
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T-cell factor 4 (Tcf7l2) maintains proliferative compartments in zebrafish intestine.
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Muncan V, Faro A, Haramis AP, Hurlstone AF, Wienholds E, van Es J, Korving J, Begthel H, Zivkovic D, and Clevers H
EMBO reports 8(10):966-73, 2007 Oct - Who cited this? | PubMed ID: 17823612 | Fulltext
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Rapid loss of intestinal crypts upon conditional deletion of the Wnt/Tcf-4 target gene c-Myc.
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Muncan V, Sansom OJ, Tertoolen L, Phesse TJ, Begthel H, Sancho E, Cole AM, Gregorieff A, de Alboran IM, Clevers H, and Clarke AR
Molecular and cellular biology 26(22):8418, 2006 Nov - Who cited this? | PubMed ID: 16954380 | Fulltext
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Adenomatous polyposis coli-deficient zebrafish are susceptible to digestive tract neoplasia.
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Haramis AP, Hurlstone A, van der Velden Y, Begthel H, van den Born M, Offerhaus GJ, and Clevers HC
EMBO reports 7(4):444-9, 2006 Apr - Who cited this? | PubMed ID: 16439994 | Fulltext
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Expression pattern of Wnt signaling components in the adult intestine.
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Gregorieff A, Pinto D, Begthel H, Destrée O, Kielman M, and Clevers H
Gastroenterology 129(2):626-38, 2005 Aug - Who cited this? | PubMed ID: 16083717 | Fulltext
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EphB receptor activity suppresses colorectal cancer progression.
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Batlle E, Bacani J, Begthel H, Jonkheer S, Gregorieff A, van de Born M, Malats N, Sancho E, Boon E, Pawson T, Gallinger S, Pals S, and Clevers H
Nature 435(7045):1126-30, 2005 Jun 23 - Who cited this? | PubMed ID: 15973414 | Fulltext
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Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells.
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van Es JH, van Gijn ME, Riccio O, van den Born M, Vooijs M, Begthel H, Cozijnsen M, Robine S, Winton DJ, Radtke F, and Clevers H
Nature 435(7044):959-63, 2005 Jun 16 - Who cited this? | PubMed ID: 15959515 | Fulltext
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Wnt signalling induces maturation of Paneth cells in intestinal crypts.
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van Es JH, Jay P, Gregorieff A, van Gijn ME, Jonkheer S, Hatzis P, Thiele A, van den Born M, Begthel H, Brabletz T, Taketo MM, and Clevers H
Nature cell biology 7(4):381-6, 2005 Apr - Who cited this? | PubMed ID: 15778706 | Fulltext
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De novo crypt formation and juvenile polyposis on BMP inhibition in mouse intestine.
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Haramis AP, Begthel H, van den Born M, van Es J, Jonkheer S, Offerhaus GJ, and Clevers H
Science (New York, N.Y.) 303(5664):1684-6, 2004 Mar 12 - Who cited this? | PubMed ID: 15017003 | Fulltext
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The Wnt/beta-catenin pathway regulates cardiac valve formation.
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Hurlstone AF, Haramis AP, Wienholds E, Begthel H, Korving J, Van Eeden F, Cuppen E, Zivkovic D, Plasterk RH, and Clevers H
Nature 425(6958):633-7, 2003 Oct 9 - Who cited this? | PubMed ID: 14534590 | Fulltext
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Canonical Wnt signals are essential for homeostasis of the intestinal epithelium.
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Pinto D, Gregorieff A, Begthel H, and Clevers H
Genes & development 17(14):1709-13, 2003 Jul 15 - Who cited this? | PubMed ID: 12865297 | Fulltext
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