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Papers authored by Barsoum J

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The novel HSP90 inhibitor STA-1474 exhibits biologic activity against osteosarcoma cell lines.

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McCleese JK, Bear MD, Fossey SL, Mihalek RM, Foley KP, Ying W, Barsoum J, and London CA

International journal of cancer. Journal international du cancer 125(12):2792-801, 2009 Dec 15 - Who cited this? | PubMed ID: 19544563 | Fulltext

Society of toxicologic pathology's 27th annual symposium presentations.

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Lin TY, Foley K, Ying W, Barsoum J, London C, Matsumoto I, Kouchi M, Okimoto K, Ueda T, Yamada T, Inoue T, Seki T, Hino O, Radi ZA, Metz A, Bruner R,

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Toxicologic pathology 37(1):123-54, 2009 - Who cited this? | PubMed ID: 19234236 | Fulltext

Elesclomol induces cancer cell apoptosis through oxidative stress.

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Kirshner JR, He S, Balasubramanyam V, Kepros J, Yang CY, Zhang M, Du Z, Barsoum J, and Bertin J

Molecular cancer therapeutics 7(8):2319-27, 2008 Aug - Who cited this? | PubMed ID: 18723479 | Fulltext

The novel HSP90 inhibitor STA-9090 exhibits activity against Kit-dependent and -independent malignant mast cell tumors.

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Lin TY, Bear M, Foley K, Ying W, Barsoum J, and London C

Experimental hematology, 2008 Jul 24 - Who cited this? | PubMed ID: 18657349 | Fulltext

Selective abrogation of Th1 response by STA-5326, a potent IL-12/IL-23 inhibitor.

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Wada Y, Lu R, Zhou D, Chu J, Przewloka T, Zhang S, Li L, Wu Y, Qin J, Balasubramanyam V, Barsoum J, and Ono M

Blood 109(3):1156-64, 2007 Feb 1 - Who cited this? | PubMed ID: 17053051 | Fulltext

Sonic hedgehog delivered by an adeno-associated virus protects dopaminergic neurones against 6-OHDA toxicity in the rat.

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Dass B, Iravani MM, Huang C, Barsoum J, Engber TM, Galdes A, and Jenner P

Journal of neural transmission (Vienna, Austria : 1996) 112(6):763-78, 2005 Jun - Who cited this? | PubMed ID: 15586304 | Fulltext

Combined 5-fluorouracil/systemic interferon-beta gene therapy results in long-term survival in mice with established colorectal liver metastases.

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Choi EA, Lei H, Maron DJ, Mick R, Barsoum J, Yu QC, Fraker DL, Wilson JM, and Spitz FR

Clinical cancer research : an official journal of the American Association for Cancer Research 10(4):1535-44, 2004 Feb 15 - Who cited this? | PubMed ID: 14977858 | Fulltext

Stat1-dependent induction of tumor necrosis factor-related apoptosis-inducing ligand and the cell-surface death signaling pathway by interferon beta in human cancer cells.

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Choi EA, Lei H, Maron DJ, Wilson JM, Barsoum J, Fraker DL, El-Deiry WS, and Spitz FR

Cancer research 63(17):5299-307, 2003 Sep 1 - Who cited this? | PubMed ID: 14500361 | Fulltext

Direct evidence that IFN-beta functions as a tumor-suppressor protein.

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Kaynor C, Xin M, Wakefield J, Barsoum J, and Qin XQ

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 22(11):1089-98, 2002 Nov - Who cited this? | PubMed ID: 12513908 | Fulltext

Cytotoxicity of combinations of IFN-beta and chemotherapeutic drugs.

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Brickelmaier M, Carmillo A, Goelz S, Barsoum J, and Qin XQ

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 22(8):873-80, 2002 Aug - Who cited this? | PubMed ID: 12396726 | Fulltext

CD4+ T helper cell-independent antitumor response mediated by murine IFN-beta gene delivery in immunocompetent mice.

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Brown JL, Barsoum J, and Qin XQ

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 22(6):719-28, 2002 Jun - Who cited this? | PubMed ID: 12162884 | Fulltext

Human and mouse IFN-beta gene therapy exhibits different anti-tumor mechanisms in mouse models.

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Qin XQ, Beckham C, Brown JL, Lukashev M, and Barsoum J

Molecular therapy : the journal of the American Society of Gene Therapy 4(4):356-64, 2001 Oct - Who cited this? | PubMed ID: 11592839 | Fulltext

Eradication of intraperitoneal and distant tumor by adenovirus-mediated interferon-beta gene therapy is attributable to induction of systemic immunity.

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Odaka M, Sterman DH, Wiewrodt R, Zhang Y, Kiefer M, Amin KM, Gao GP, Wilson JM, Barsoum J, Kaiser LR, and Albelda SM

Cancer research 61(16):6201-12, 2001 Aug 15 - Who cited this? | PubMed ID: 11507073 | Fulltext

Systemic IFN-beta gene therapy results in long-term survival in mice with established colorectal liver metastases.

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Tada H, Maron DJ, Choi EA, Barsoum J, Lei H, Xie Q, Liu W, Ellis L, Moscioni AD, Tazelaar J, Fawell S, Qin X, Propert KJ, Davis A, Fraker DL, Wilson JM,

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The Journal of clinical investigation 108(1):83-95, 2001 Jul - Who cited this? | PubMed ID: 11435460 | Fulltext

Sevelamer, Ca x P product and vitamin D.

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Fournier A, Barsoum J, Fickl R, Oprisiu R, El Esper N, and Moriniere P

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 16(2):429-30, 2001 Feb - Who cited this? | PubMed ID: 11158431 | Fulltext

Sequestration of adenoviral vector by Kupffer cells leads to a nonlinear dose response of transduction in liver.

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Tao N, Gao GP, Parr M, Johnston J, Baradet T, Wilson JM, Barsoum J, and Fawell SE

Molecular therapy : the journal of the American Society of Gene Therapy 3(1):28-35, 2001 Jan - Who cited this? | PubMed ID: 11162308 | Fulltext

Concentration of recombinant baculovirus by cation-exchange chromatography.

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Barsoum J

BioTechniques 26(5):834-6, 838, 840, 1999 May - Who cited this? | PubMed ID: 10337471 | Fulltext

Baculovirus vector requires electrostatic interactions including heparan sulfate for efficient gene transfer in mammalian cells.

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Duisit G, Saleun S, Douthe S, Barsoum J, Chadeuf G, and Moullier P

The journal of gene medicine 1(2):93-102, 1999 - Who cited this? | PubMed ID: 10738573 | Fulltext

Interferon-beta gene therapy inhibits tumor formation and causes regression of established tumors in immune-deficient mice.

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Qin XQ, Tao N, Dergay A, Moy P, Fawell S, Davis A, Wilson JM, and Barsoum J

Proceedings of the National Academy of Sciences of the United States of America 95(24):14411-6, 1998 Nov 24 - Who cited this? | PubMed ID: 9826714 | Fulltext

Efficient transduction of mammalian cells by a recombinant baculovirus having the vesicular stomatitis virus G glycoprotein.

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Barsoum J, Brown R, McKee M, and Boyce FM

Human gene therapy 8(17):2011-8, 1997 Nov 20 - Who cited this? | PubMed ID: 9414250 | Fulltext

Interferon-beta induces S phase accumulation selectively in human transformed cells.

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Qin XQ, Runkel L, Deck C, DeDios C, and Barsoum J

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 17(6):355-67, 1997 Jun - Who cited this? | PubMed ID: 9198003 | Fulltext

Differential cell cycle effects induced by E2F1 mutants.

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Qin XQ and Barsoum J

Oncogene 14(1):53-62, 1997 Jan 9 - Who cited this? | PubMed ID: 9010232 | Fulltext

Sequences flanking the core DNA-binding domain of bovine papillomavirus type 1 E2 contribute to DNA-binding function.

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Pepinsky RB, Prakash SS, Corina K, Grossel MJ, Barsoum J, and Androphy EJ

Journal of virology 71(1):828-31, 1997 Jan - Who cited this? | PubMed ID: 8985425 | Fulltext

Tat-mediated protein delivery can facilitate MHC class I presentation of antigens.

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Moy P, Daikh Y, Pepinsky B, Thomas D, Fawell S, and Barsoum J

Molecular biotechnology 6(2):105-13, 1996 Oct - Who cited this? | PubMed ID: 8970166 | Fulltext

The BPV-1 E2 DNA-contact helix cysteine is required for transcriptional activation but not replication in mammalian cells.

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Grossel MJ, Barsoum J, Prakash SS, and Androphy EJ

Virology 217(1):301-10, 1996 Mar 1 - Who cited this? | PubMed ID: 8599215 | Fulltext

Endosomolytic activity of cationic liposomes enhances the delivery of human immunodeficiency virus-1 trans-activator protein (TAT) to mammalian cells.

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Huang L, Farhood H, Serbina N, Teepe AG, and Barsoum J

Biochemical and biophysical research communications 217(3):761-8, 1995 Dec 26 - Who cited this? | PubMed ID: 8554596 | Fulltext

Increased cellular uptake of the human immunodeficiency virus-1 Tat protein after modification with biotin.

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Chen LL, Frankel AD, Harder JL, Fawell S, Barsoum J, and Pepinsky B

Analytical biochemistry 227(1):168-75, 1995 May 1 - Who cited this? | PubMed ID: 7668378 | Fulltext

Codelivery to mammalian cells of a transcriptional factor with cis-acting element using cationic liposomes.

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Farhood H, Gao X, Barsoum J, and Huang L

Analytical biochemistry 225(1):89-93, 1995 Feb 10 - Who cited this? | PubMed ID: 7778790 | Fulltext

Stable integration of vectors at high copy number for high-level expression in animal cells.

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Barsoum J

Methods in molecular biology (Clifton, N.J.) 48:225-37, 1995 - Who cited this? | PubMed ID: 8528394 | Fulltext

Specific inhibition of a human papillomavirus E2 trans-activator by intracellular delivery of its repressor.

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Pepinsky RB, Androphy EJ, Corina K, Brown R, and Barsoum J

DNA and cell biology 13(10):1011-9, 1994 Oct - Who cited this? | PubMed ID: 7945933 | Fulltext

Cationic liposomes for direct gene transfer in therapy of cancer and other diseases.

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Farhood H, Gao X, Son K, Yang YY, Lazo JS, Huang L, Barsoum J, Bottega R, and Epand RM

Annals of the New York Academy of Sciences 716:23-34; discussion 34-5, 1994 May 31 - Who cited this? | PubMed ID: 8024197 | Fulltext

Tat-mediated delivery of heterologous proteins into cells.

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Fawell S, Seery J, Daikh Y, Moore C, Chen LL, Pepinsky B, and Barsoum J

Proceedings of the National Academy of Sciences of the United States of America 91(2):664-8, 1994 Jan 18 - Who cited this? | PubMed ID: 8290579 | Fulltext

The tryptophan bridge is a critical feature of the papillomavirus E2 DNA binding domain.

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Corina K, Grossman SR, Barsoum J, Prakash SS, Androphy EJ, and Pepinsky RB

Virology 197(1):391-6, 1993 Nov - Who cited this? | PubMed ID: 8212573 | Fulltext

Mechanism of action of the papillomavirus E2 repressor: repression in the absence of DNA binding.

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Barsoum J, Prakash SS, Han P, and Androphy EJ

Journal of virology 66(6):3941-5, 1992 Jun - Who cited this? | PubMed ID: 1316493 | Fulltext

Transactivation of heterologous promoters by HIV-1 tat.

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Han P, Brown R, and Barsoum J

Nucleic acids research 19(25):7225-9, 1991 Dec - Who cited this? | PubMed ID: 1662814 | Fulltext

Introduction of stable high-copy-number DNA into Chinese hamster ovary cells by electroporation.

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Barsoum J

DNA and cell biology 9(4):293-300, 1990 May - Who cited this? | PubMed ID: 2112395 | Fulltext

Trans activation by the bovine papillomavirus E2 protein in Saccharomyces cerevisiae.

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Morrissey LC, Barsoum J, and Androphy EJ

Journal of virology 63(10):4422-5, 1989 Oct - Who cited this? | PubMed ID: 2550673 | Fulltext

Simian virus 40 minichromosomes contain torsionally strained DNA molecules.

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Barsoum J and Berg P

Molecular and cellular biology 5(11):3048-57, 1985 Nov - Who cited this? | PubMed ID: 3018497 | Fulltext

Preferential localization of variant nucleosomes near the 5'-end of the mouse dihydrofolate reductase gene.

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Barsoum J and Varshavsky A

The Journal of biological chemistry 260(12):7688-97, 1985 Jun 25 - Who cited this? | PubMed ID: 2987265 | Fulltext

Mitogenic hormones and tumor promoters greatly increase the incidence of colony-forming cells bearing amplified dihydrofolate reductase genes.

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Barsoum J and Varshavsky A

Proceedings of the National Academy of Sciences of the United States of America 80(17):5330-4, 1983 Sep - Who cited this? | PubMed ID: 6351057 | Fulltext

Cellular and SV40 chromatin: replication, segregation, ubiquitination, nuclease-hypersensitive sites, HMG-containing nucleosomes, and heterochromatin-specific protein.

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Varshavsky A, Levinger L, Sundin O, Barsoum J, Ozkaynak E, Swerdlow P, and Finley D

Cold Spring Harbor symposia on quantitative biology 47 Pt 1:511-28, 1983 - Who cited this? | PubMed ID: 6305564 | Fulltext

Acquisition and loss of amplified genes: dramatic effects of hormones, tumor promoters and cytotoxic drugs.

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Varshavsky A, Barsoum J, Roninson I, and Snapka R

Princess Takamatsu symposia 14:235-54, 1983 - Who cited this? | PubMed ID: 6394591 | Fulltext

On the chromatin structure of the amplified, transcriptionally active gene for dihydrofolate reductase in mouse cells.

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Barsoum J, Levinger L, and Varshavsky A

The Journal of biological chemistry 257(9):5274-82, 1982 May 10 - Who cited this? | PubMed ID: 6896057 | Fulltext

New way to isolate simian virus 40 nucleoprotein complexes from infected cells: use of a thiol-specific reagent.

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Boyce FM, Sundin O, Barsoum J, and Varshavsky A

Journal of virology 42(1):292-6, 1982 Apr - Who cited this? | PubMed ID: 6283146 | Fulltext

Two-dimensional hybridization mapping of nucleosomes. comparison of DNA and protein patterns.

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Levinger L, Barsoum J, and Varshavsky A

Journal of molecular biology 146(3):287-304, 1981 Mar 5 - Who cited this? | PubMed ID: 7265232 | Fulltext

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