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Papers authored by Attardi LD

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Differential PERP regulation by TP63 mutants provides insight into AEC pathogenesis.

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Beaudry VG, Pathak N, Koster MI, and Attardi LD

American journal of medical genetics. Part A 149A(9):1952-7, 2009 Sep - Who cited this? | PubMed ID: 19353588 | Fulltext

International Research Symposium on Ankyloblepharon-Ectodermal Defects-Cleft Lip/Palate (AEC) syndrome.

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Fete M, vanBokhoven H, Clements SE, McKeon F, Roop DR, Koster MI, Missero C, Attardi LD, Lombillo VA, Ratovitski E, Julapalli M, Ruths D, Sybert VP, Siegfried EC, and Bree AF

American journal of medical genetics. Part A 149A(9):1885-93, 2009 Sep - Who cited this? | PubMed ID: 19353643 | Fulltext

SKP-ing TAp63: stem cell depletion, senescence, and premature aging.

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Beaudry VG and Attardi LD

Cell stem cell 5(1):1-2, 2009 Jul 2 - Who cited this? | PubMed ID: 19570504 | Fulltext

Loss of the desmosomal protein perp enhances the phenotypic effects of pemphigus vulgaris autoantibodies.

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Nguyen B, Dusek RL, Beaudry VG, Marinkovich MP, and Attardi LD

The Journal of investigative dermatology 129(7):1710-8, 2009 Jul - Who cited this? | PubMed ID: 19158843 | Fulltext

Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects.

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McGowan KA, Li JZ, Park CY, Beaudry V, Tabor HK, Sabnis AJ, Zhang W, Fuchs H, de Angelis MH, Myers RM, Attardi LD, and Barsh GS

Nature genetics 40(8):963, 2008 Aug - Who cited this? | PubMed ID: 18641651 | Fulltext

The metastasis-associated gene Prl-3 is a p53 target involved in cell-cycle regulation.

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Basak S, Jacobs SB, Krieg AJ, Pathak N, Zeng Q, Kaldis P, Giaccia AJ, and Attardi LD

Molecular cell 30(3):303, 2008 May 9 - Who cited this? | PubMed ID: 18471976 | Fulltext

Knockin mice expressing a chimeric p53 protein reveal mechanistic differences in how p53 triggers apoptosis and senescence.

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Johnson TM, Meade K, Pathak N, Marques MR, and Attardi LD

Proceedings of the National Academy of Sciences of the United States of America 105(4):1215, 2008 Jan 29 - Who cited this? | PubMed ID: 18216268 | Fulltext

Siva is an apoptosis-selective p53 target gene important for neuronal cell death.

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Jacobs SB, Basak S, Murray JI, Pathak N, and Attardi LD

Cell death and differentiation 14(7):1374-85, 2007 Jul - Who cited this? | PubMed ID: 17464332 | Fulltext

A healthy tan?.

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Barsh G and Attardi LD

The New England journal of medicine 356(21):2208-10, 2007 May 24 - Who cited this? | PubMed ID: 17522405 | Fulltext

Dominant-negative but not gain-of-function effects of a p53.R270H mutation in mouse epithelium tissue after DNA damage.

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Wijnhoven SW, Speksnijder EN, Liu X, Zwart E, vanOostrom CT, Beems RB, Hoogervorst EM, Schaap MM, Attardi LD, Jacks T, van Steeg H, Jonkers J, and de Vries A

Cancer research 67(10):4648-56, 2007 May 15 - Who cited this? | PubMed ID: 17510390 | Fulltext

p63, cell adhesion and survival.

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Carroll DK, Brugge JS, and Attardi LD

Cell cycle (Georgetown, Tex.) 6(3):255-61, 2007 Feb - Who cited this? | PubMed ID: 17297292 | Fulltext

Adult mice lacking the p53/p63 target gene Perp are not predisposed to spontaneous tumorigenesis but display features of ectodermal dysplasia syndromes.

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Ihrie RA, Bronson RT, and Attardi LD

Cell death and differentiation 13(9):1614-8, 2006 Sep - Who cited this? | PubMed ID: 16485031 | Fulltext

Dissecting p53 tumor suppressor function in vivo through the analysis of genetically modified mice.

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Johnson TM and Attardi LD

Cell death and differentiation 13(6):902-8, 2006 Jun - Who cited this? | PubMed ID: 16557272 | Fulltext

Genome-wide analysis of p53 under hypoxic conditions.

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Hammond EM, Mandell DJ, Salim A, Krieg AJ, Johnson TM, Shirazi HA, Attardi LD, and Giaccia AJ

Molecular and cellular biology 26(9):3492-504, 2006 May - Who cited this? | PubMed ID: 16611991 | Fulltext

The requirement for perp in postnatal viability and epithelial integrity reflects an intrinsic role in stratified epithelia.

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Marques MR, Ihrie RA, Horner JS, and Attardi LD

The Journal of investigative dermatology 126(1):69, 2006 Jan - Who cited this? | PubMed ID: 16417219 | Fulltext

Probing p53 biological functions through the use of genetically engineered mouse models.

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Attardi LD and Donehower LA

Mutation research 576(1-2):4-21, 2005 Aug 25 - Who cited this? | PubMed ID: 16038709 | Fulltext

Mice lacking the p53/p63 target gene Perp are resistant to papilloma development.

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Marques MR, Horner JS, Ihrie RA, Bronson RT, and Attardi LD

Cancer research 65(15):6551-6, 2005 Aug 1 - Who cited this? | PubMed ID: 16061634 | Fulltext

A new Perp in the lineup: linking p63 and desmosomal adhesion.

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Ihrie RA and Attardi LD

Cell cycle (Georgetown, Tex.) 4(7):873-6, 2005 Jul - Who cited this? | PubMed ID: 15970683 | Fulltext

Pathways connecting telomeres and p53 in senescence, apoptosis, and cancer.

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Artandi SE and Attardi LD

Biochemical and biophysical research communications 331(3):881-90, 2005 Jun 10 - Who cited this? | PubMed ID: 15865944 | Fulltext

p53QS: an old mutant teaches us new tricks.

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Johnson TM and Attardi LD

Cell cycle (Georgetown, Tex.) 4(6):731-4, 2005 Jun - Who cited this? | PubMed ID: 15908788 | Fulltext

Perp is a p63-regulated gene essential for epithelial integrity.

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Ihrie RA, Marques MR, Nguyen BT, Horner JS, Papazoglu C, Bronson RT, Mills AA, and Attardi LD

Cell 120(6):843, 2005 Mar 25 - Who cited this? | PubMed ID: 15797384 | Fulltext

The role of apoptosis in cancer development and treatment response.

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Brown JM and Attardi LD

Nature reviews. Cancer 5(3):231-7, 2005 Mar - Who cited this? | PubMed ID: 15738985 | Fulltext

The p53QS transactivation-deficient mutant shows stress-specific apoptotic activity and induces embryonic lethality.

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Johnson TM, Hammond EM, Giaccia A, and Attardi LD

Nature genetics 37(2):145-52, 2005 Feb - Who cited this? | PubMed ID: 15654339 | Fulltext

The role of p53-mediated apoptosis as a crucial anti-tumor response to genomic instability: lessons from mouse models.

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Attardi LD

Mutation research 569(1-2):145-57, 2005 Jan 6 - Who cited this? | PubMed ID: 15603759 | Fulltext

Developmental context determines latency of MYC-induced tumorigenesis.

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Beer S, Zetterberg A, Ihrie RA, McTaggart RA, Yang Q, Bradon N, Arvanitis C, Attardi LD, Feng S, Ruebner B, Cardiff RD, and Felsher DW

PLoS biology 2(11):0, 2004 Nov - Who cited this? | PubMed ID: 15455033 | Fulltext

Increased sensitivity to UV radiation in mice with a p53 point mutation at Ser389.

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Bruins W, Zwart E, Attardi LD, Iwakuma T, Hoogervorst EM, Beems RB, Miranda B, Van Oostrom CT, van den Berg J, van den Aardweg GJ, Lozano G, van Steeg H, Jacks T, and de Vries A

Molecular and cellular biology 24(20):8884, 2004 Oct - Who cited this? | PubMed ID: 15456863 | Fulltext

Perp-etrating p53-dependent apoptosis.

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Ihrie RA and Attardi LD

Cell cycle (Georgetown, Tex.) 3(3):267-9, 2004 Mar - Who cited this? | PubMed ID: 14726658 | Fulltext

Activation of the p53-dependent G1 checkpoint response in mouse embryo fibroblasts depends on the specific DNA damage inducer.

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Attardi LD, de Vries A, and Jacks T

Oncogene 23(4):973, 2004 Jan 29 - Who cited this? | PubMed ID: 14749764 | Fulltext

Conquering the complexity of p53.

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Attardi LD and DePinho RA

Nature genetics 36(1):7-8, 2004 Jan - Who cited this? | PubMed ID: 14702030 | Fulltext

Multiple response elements and differential p53 binding control Perp expression during apoptosis.

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Reczek EE, Flores ER, Tsay AS, Attardi LD, and Jacks T

Molecular cancer research : MCR 1(14):1048, 2003 Dec - Who cited this? | PubMed ID: 14707288 | Fulltext

Perp is a mediator of p53-dependent apoptosis in diverse cell types.

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Ihrie RA, Reczek E, Horner JS, Khachatrian L, Sage J, Jacks T, and Attardi LD

Current biology : CB 13(22):1985-90, 2003 Nov 11 - Who cited this? | PubMed ID: 14614825 | Fulltext

Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization.

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Sage J, Mulligan GJ, Attardi LD, Miller A, Chen S, Williams B, Theodorou E, and Jacks T

Genes & development 14(23):3037, 2000 Dec 1 - Who cited this? | PubMed ID: 11114892 | Fulltext

PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family.

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Attardi LD, Reczek EE, Cosmas C, Demicco EG, McCurrach ME, Lowe SW, and Jacks T

Genes & development 14(6):704-18, 2000 Mar 15 - Who cited this? | PubMed ID: 10733530 | Fulltext

The role of p53 in tumour suppression: lessons from mouse models.

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Attardi LD and Jacks T

Cellular and molecular life sciences : CMLS 55(1):48-63, 1999 Jan - Who cited this? | PubMed ID: 10065151 | Fulltext

Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis.

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Attardi LD, Lowe SW, Brugarolas J, and Jacks T

The EMBO journal 15(14):3693-701, 1996 Jul 15 - Who cited this? | PubMed ID: 8758936 | Fulltext

A subset of p53-deficient embryos exhibit exencephaly.

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Sah VP, Attardi LD, Mulligan GJ, Williams BO, Bronson RT, and Jacks T

Nature genetics 10(2):175-80, 1995 Jun - Who cited this? | PubMed ID: 7663512 | Fulltext

Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators.

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Chen JL, Attardi LD, Verrijzer CP, Yokomori K, and Tjian R

Cell 79(1):93-105, 1994 Oct 7 - Who cited this? | PubMed ID: 7923382 | Fulltext

Ectopic expression of wild-type or a dominant-negative mutant of transcription factor NTF-1 disrupts normal Drosophila development.

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Attardi LD, Von Seggern D, and Tjian R

Proceedings of the National Academy of Sciences of the United States of America 90(22):10563-7, 1993 Nov 15 - Who cited this? | PubMed ID: 8248145 | Fulltext

Drosophila tissue-specific transcription factor NTF-1 contains a novel isoleucine-rich activation motif.

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Attardi LD and Tjian R

Genes & development 7(7B):1341-53, 1993 Jul - Who cited this? | PubMed ID: 8330738 | Fulltext

In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs.

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Yu GL, Bradley JD, Attardi LD, and Blackburn EH

Nature 344(6262):126-32, 1990 Mar 8 - Who cited this? | PubMed ID: 1689810 | Fulltext

Functional analysis of NTF-1, a developmentally regulated Drosophila transcription factor that binds neuronal cis elements.

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Dynlacht BD, Attardi LD, Admon A, Freeman M, and Tjian R

Genes & development 3(11):1677-88, 1989 Nov - Who cited this? | PubMed ID: 2606344 | Fulltext

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