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Papers authored by Andersen OA

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Cross-linking of protein crystals as an aid in the generation of binary protein-ligand crystal complexes, exemplified by the human PDE10a-papaverine structure.

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Andersen OA, Schönfeld DL, Toogood-Johnson I, Felicetti B, Albrecht C, Fryatt T, Whittaker M, Hallett D, and Barker J

Acta crystallographica. Section D, Biological crystallography 65(Pt 8):872-4, 2009 Aug - Who cited this? | PubMed ID: 19622871 | Fulltext

Solid-phase synthesis of cyclic peptide chitinase inhibitors: SAR of the argifin scaffold.

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Dixon MJ, Nathubhai A, Andersen OA, van Aalten DM, and Eggleston IM

Organic & biomolecular chemistry 7(2):259-68, 2009 Jan 21 - Who cited this? | PubMed ID: 19109670 | Fulltext

SPPS of the natural product chitinase inhibitor argifin: library generation and biological evaluation.

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Dixon MJ, Andersen OA, van Aalten DM, and Eggleston IM

Advances in experimental medicine and biology 611:143-4, 2009 - Who cited this? | PubMed ID: 19400131 | Fulltext

Synthesis and structure-based dissection of cyclic peptide chitinase inhibitors: new leads for antifungal and anti-inflammatory drugs.

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Dixon MJ, Nathubhai A, Andersen OA, van Aalten DM, and Eggleston IM

Advances in experimental medicine and biology 611:525-6, 2009 - Who cited this? | PubMed ID: 19400296 | Fulltext

Structure-based dissection of the natural product cyclopentapeptide chitinase inhibitor argifin.

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Andersen OA, Nathubhai A, Dixon MJ, Eggleston IM, and van Aalten DM

Chemistry & biology 15(3):295, 2008 Mar - Who cited this? | PubMed ID: 18355729 | Fulltext

Structural basis for enzymatic excision of N1-methyladenine and N3-methylcytosine from DNA.

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Leiros I, Nabong MP, Grøsvik K, Ringvoll J, Haugland GT, Uldal L, Reite K, Olsbu IK, Knaevelsrud I, Moe E, Andersen OA, Birkeland NK, Ruoff P, Klungland A, and Bjelland S

The EMBO journal 26(8):2206, 2007 Apr 18 - Who cited this? | PubMed ID: 17396151 | Fulltext

Crystal structure of alkaline phosphatase from the Antarctic bacterium TAB5.

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Wang E, Koutsioulis D, Leiros HK, Andersen OA, Bouriotis V, Hough E, and Heikinheimo P

Journal of molecular biology 366(4):1318-31, 2007 Mar 2 - Who cited this? | PubMed ID: 17198711 | Fulltext

Screening-based discovery and structural dissection of a novel family 18 chitinase inhibitor.

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Schüttelkopf AW, Andersen OA, Rao FV, Allwood M, Lloyd C, Eggleston IM, and van Aalten DM

The Journal of biological chemistry 281(37):27278-85, 2006 Sep 15 - Who cited this? | PubMed ID: 16844689 | Fulltext

An efficient synthesis of argifin: a natural product chitinase inhibitor with chemotherapeutic potential.

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Dixon MJ, Andersen OA, van Aalten DM, and Eggleston IM

Bioorganic & medicinal chemistry letters 15(21):4717, 2005 Nov 1 - Who cited this? | PubMed ID: 16153835 | Fulltext

Natural product family 18 chitinase inhibitors.

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Andersen OA, Dixon MJ, Eggleston IM, and van Aalten DM

Natural product reports 22(5):563, 2005 Oct - Who cited this? | PubMed ID: 16193156 | Fulltext

Methylxanthine drugs are chitinase inhibitors: investigation of inhibition and binding modes.

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Rao FV, Andersen OA, Vora KA, Demartino JA, and van Aalten DM

Chemistry & biology 12(9):973-80, 2005 Sep - Who cited this? | PubMed ID: 16183021 | Fulltext

Trypsin specificity as elucidated by LIE calculations, X-ray structures, and association constant measurements.

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Leiros HK, Brandsdal BO, Andersen OA, Os V, Leiros I, Helland R, Otlewski J, Willassen NP, and Smalås AO

Protein science : a publication of the Protein Society 13(4):1056-70, 2004 Apr - Who cited this? | PubMed ID: 15044735 | Fulltext

2.0A resolution crystal structures of the ternary complexes of human phenylalanine hydroxylase catalytic domain with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine or L-norleucine: substrate specificity and molecular motions related to substrate binding.

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Andersen OA, Stokka AJ, Flatmark T, and Hough E

Journal of molecular biology 333(4):747-57, 2003 Oct 31 - Who cited this? | PubMed ID: 14568534 | Fulltext

Deamidation of labile asparagine residues in the autoregulatory sequence of human phenylalanine hydroxylase.

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Solstad T, Carvalho RN, Andersen OA, Waidelich D, and Flatmark T

European journal of biochemistry / FEBS 270(5):929, 2003 Mar - Who cited this? | PubMed ID: 12603326 | Fulltext

Studies on the regulatory properties of the pterin cofactor and dopamine bound at the active site of human phenylalanine hydroxylase.

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Solstad T, Stokka AJ, Andersen OA, and Flatmark T

European journal of biochemistry / FEBS 270(5):981-90, 2003 Mar - Who cited this? | PubMed ID: 12603331 | Fulltext

Crystal structure of the ternary complex of the catalytic domain of human phenylalanine hydroxylase with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine, and its implications for the mechanism of catalysis and substrate activation.

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Andersen OA, Flatmark T, and Hough E

Journal of molecular biology 320(5):1095-108, 2002 Jul 26 - Who cited this? | PubMed ID: 12126628 | Fulltext

High resolution crystal structures of the catalytic domain of human phenylalanine hydroxylase in its catalytically active Fe(II) form and binary complex with tetrahydrobiopterin.

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Andersen OA, Flatmark T, and Hough E

Journal of molecular biology 314(2):279-91, 2001 Nov 23 - Who cited this? | PubMed ID: 11718561 | Fulltext

High-resolution structures of three new trypsin-squash-inhibitor complexes: a detailed comparison with other trypsins and their complexes.

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Helland R, Berglund GI, Otlewski J, Apostoluk W, Andersen OA, Willassen NP, and Smalås AO

Acta crystallographica. Section D, Biological crystallography 55(Pt 1):139-48, 1999 Jan - Who cited this? | PubMed ID: 10089404 | Fulltext

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