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Papers authored by Akita H

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Immunohistochemical localization of the STRO-1 antigen in developing rat teeth by light microscopy and electron microscopy.

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Kaneko R, Akita H, Shimauchi H, and Sasano Y

Journal of electron microscopy 58(6):363-73, 2009 Dec - Who cited this? | PubMed ID: 19525367 | Fulltext

A pH-sensitive fusogenic peptide facilitates endosomal escape and greatly enhances the gene silencing of siRNA-containing nanoparticles in vitro and in vivo.

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Hatakeyama H, Ito E, Akita H, Oishi M, Nagasaki Y, Futaki S, and Harashima H

Journal of controlled release : official journal of the Controlled Release Society 139(2):127-32, 2009 Oct 15 - Who cited this? | PubMed ID: 19540888 | Fulltext

First syntheses of (-)-tauranin and antibiotic (-)-BE-40644 based on lipase-catalyzed optical resolution of albicanol.

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Ishii S, Fujii M, and Akita H

Chemical & pharmaceutical bulletin 57(10):1103-6, 2009 Oct - Who cited this? | PubMed ID: 19801866 | Fulltext

Envelope-type lipid nanoparticles incorporating a short PEG-lipid conjugate for improved control of intracellular trafficking and transgene transcription.

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Masuda T, Akita H, Niikura K, Nishio T, Ukawa M, Enoto K, Danev R, Nagayama K, Ijiro K, and Harashima H

Biomaterials 30(27):4806-14, 2009 Sep - Who cited this? | PubMed ID: 19520424 | Fulltext

Enhanced gene expression by a novel stearylated INF7 peptide derivative through fusion independent endosomal escape.

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El-Sayed A, Masuda T, Khalil I, Akita H, and Harashima H

Journal of controlled release : official journal of the Controlled Release Society 138(2):160-7, 2009 Sep 1 - Who cited this? | PubMed ID: 19465073 | Fulltext

Significance of RRM1 and ERCC1 expression in resectable pancreatic adenocarcinoma.

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Akita H, Zheng Z, Takeda Y, Kim C, Kittaka N, Kobayashi S, Marubashi S, Takemasa I, Nagano H, Dono K, Nakamori S, Monden M, Mori M, Doki Y, and Bepler G

Oncogene 28(32):2903-9, 2009 Aug 13 - Who cited this? | PubMed ID: 19543324 | Fulltext

[Molecular targeted drugs in the developmental stage: 2) Various molecular targets and therapeutic agents under investigation].

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Akita H

Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 98(8):1894-900, 2009 Aug 10 - Who cited this? | PubMed ID: 19894350 | Fulltext

Structural insight into the binding mode between the targeting domain of ALE-1 (92AA) and pentaglycine of peptidoglycan.

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Hirakawa H, Akita H, Fujiwara T, Sugai M, and Kuhara S

Protein engineering, design & selection : PEDS 22(7):385-91, 2009 Jul - Who cited this? | PubMed ID: 19457979 | Fulltext

Effect of polyethyleneglycol spacer on the binding properties of nuclear localization signal-modified liposomes to isolated nucleus.

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Kurihara D, Akita H, Kudo A, Masuda T, Futaki S, and Harashima H

Biological & pharmaceutical bulletin 32(7):1303-6, 2009 Jul - Who cited this? | PubMed ID: 19571404 | Fulltext

Novel lipidated sorbitol-based molecular transporters for non-viral gene delivery.

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Higashi T, Khalil IA, Maiti KK, Lee WS, Akita H, Harashima H, and Chung SK

Journal of controlled release : official journal of the Controlled Release Society 136(2):140-7, 2009 Jun 5 - Who cited this? | PubMed ID: 19331845 | Fulltext

A case of primary retroperitoneal mucinous cystadenocarcinoma.

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Ichiya T, Nomura M, Mitsui S, Shida H, Komaba F, Kin T, Yane K, Matsui T, Nishimori H, Tsuji K, Kang J, Osanai M, Katanuma A, Takahashi K, Maguchi H, Shinohara T,

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Nippon Shokakibyo Gakkai zasshi The Japanese journal of gastro-enterology 106(6):826-33, 2009 Jun - Who cited this? | PubMed ID: 19498315 | Fulltext

Multi-layered nanoparticles for penetrating the endosome and nuclear membrane via a step-wise membrane fusion process.

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Akita H, Kudo A, Minoura A, Yamaguti M, Khalil IA, Moriguchi R, Masuda T, Danev R, Nagayama K, Kogure K, and Harashima H

Biomaterials 30(15):2940-9, 2009 May - Who cited this? | PubMed ID: 19261326 | Fulltext

Efficient Short Interference RNA Delivery to Tumor Cells Using a Combination of Octaarginine, GALA and Tumor-Specific, Cleavable Polyethylene Glycol System.

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Sakurai Y, Hatakeyama H, Akita H, Oishi M, Nagasaki Y, Futaki S, and Harashima H

Biological & pharmaceutical bulletin 32(5):928-32, 2009 May - Who cited this? | PubMed ID: 19420766 | Fulltext

Delivery may affect arterial elasticity in women.

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Hashimoto M, Miyamoto Y, Iwai C, Matsuda Y, Hiraoka E, Kanazawa K, Nishimura K, Sugiyama D, Ito K, Yamori Y, and Akita H

Circulation journal : official journal of the Japanese Circulation Society 73(4):750-4, 2009 Apr - Who cited this? | PubMed ID: 19225209 | Fulltext

Intermolecular methoxycarbonylation of terminal alkynes catalyzed by palladium(II) bis(oxazoline) complexes.

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Kato K, Motodate S, Mochida T, Kobayashi T, and Akita H

Angewandte Chemie (International ed. in English) 48(18):3326-8, 2009 - Who cited this? | PubMed ID: 19191366 | Fulltext

The single-knot method with Lapra-Ty clips is useful for training surgeons in vesicourethral anastomosis during laparoscopic radical prostatectomy.

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Yasui T, Itoh Y, Maruyama T, Akita H, Hashimoto Y, Tozawa K, and Kohri K

International urology and nephrology 41(2):281-5, 2009 - Who cited this? | PubMed ID: 18568411 | Fulltext

Advantages of Second Line Estramustine for Overall Survival of Hormone-Refractory Prostate Cancer (HRPC) Patients.

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Naiki T, Okamura T, Kawai N, Sakagami H, Yamada Y, Fujita K, Akita H, Hashimoto Y, Tozawa K, and Kohri K

Asian Pacific journal of cancer prevention : APJCP 10(1):71-4, 2009 - Who cited this? | PubMed ID: 19469628 | Fulltext

Effects of neoadjuvant chemotherapy on primary tumor and lymph node metastasis in esophageal squamous cell carcinoma: additive association with prognosis.

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Akita H, Doki Y, Yano M, Miyata H, Miyashiro I, Ohigashi H, Ishikawa O, Nishiyama A, and Imaoka S

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E 22(4):291-7, 2009 - Who cited this? | PubMed ID: 19021686 | Fulltext

A foreign body granuloma after gastric perforation mimicking peritoneal dissemination of gastric cancer: report of a case.

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Akita H, Watanabe Y, Ishida H, Nakaguchi K, Okino T, and Kabuto T

Surgery today 39(9):795-9, 2009 - Who cited this? | PubMed ID: 19779777 | Fulltext

Real-time intraoperative assessment of residual liver functional reserve using pulse dye densitometry.

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Akita H, Sasaki Y, Yamada T, Gotoh K, Ohigashi H, Eguchi H, Yano M, Ishikawa O, and Imaoka S

World journal of surgery 32(12):2668-74, 2008 Dec - Who cited this? | PubMed ID: 18841411 | Fulltext

Sharpea azabuensis gen. nov., sp. nov., a Gram-positive, strictly anaerobic bacterium isolated from the faeces of thoroughbred horses.

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Morita H, Shiratori C, Murakami M, Takami H, Toh H, Kato Y, Nakajima F, Takagi M, Akita H, Masaoka T, and Hattori M

International journal of systematic and evolutionary microbiology 58(Pt 12):2682-6, 2008 Dec - Who cited this? | PubMed ID: 19060040 | Fulltext

Oligosaccharide-mediated nuclear transport of nanoparticles.

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Niikura K, Sekiguchi S, Nishio T, Masuda T, Akita H, Matsuo Y, Kogure K, Harashima H, and Ijiro K

Chembiochem : a European journal of chemical biology 9(16):2623-7, 2008 Nov 3 - Who cited this? | PubMed ID: 18821556 | Fulltext

Conversion of optically active hydrindanone to (+)-bakkenolide-a.

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Kusakabe T, Kato K, Motodate S, Takaishi S, and Akita H

Chemical & pharmaceutical bulletin 56(10):1436-7, 2008 Oct - Who cited this? | PubMed ID: 18827385 | Fulltext

Testicular metastasis from an extramedullary plasmacytoma.

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Kamisawa H, Akita H, Naiki T, Kato T, and Okamura T

International journal of clinical oncology / Japan Society of Clinical Oncology 13(5):464-6, 2008 Oct - Who cited this? | PubMed ID: 18946760 | Fulltext

Efficacy of bacillus Calmette-Guérin in the treatment of superficial bladder cancer: the impact of previous intravesical treatment.

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Okamura T, Akita H, Imura M, Kaneko T, Mizuno K, Tozawa K, and Kohri K

International journal of urology : official journal of the Japanese Urological Association 15(11):976-80, 2008 Oct - Who cited this? | PubMed ID: 18721199 | Fulltext

Craniocervical paraganglioma with numerous pulmonary metastases.

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Kamoshima Y, Sawamura Y, Hokari M, Iwasaki Y, and Akita H

Neurologia medico-chirurgica 48(9):401, 2008 Sep - Who cited this? | PubMed ID: 18812683 | Fulltext

meso-Phbox-Pd(ii) catalyzed tandem carbonylative cyclization of 1-ethynyl-1-propargyl acetate.

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Kato K, Teraguchi R, Motodate S, Uchida A, Mochida T, Peganova TA, Vologdin NV, and Akita H

Chemical communications (Cambridge, England)(31):3687-9, 2008 Aug 21 - Who cited this? | PubMed ID: 18665300 | Fulltext

Advances in non-viral gene delivery: using multifunctional envelope-type nano-device.

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Akita H and Harashima H

Expert opinion on drug delivery 5(8):847-59, 2008 Aug - Who cited this? | PubMed ID: 18712995 | Fulltext

Supramolecular control of polyplex dissociation and cell transfection: Efficacy of amino groups and threading cyclodextrins in biocleavable polyrotaxanes.

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Yamashita A, Kanda D, Katoono R, Yui N, Ooya T, Maruyama A, Akita H, Kogure K, and Harashima H

Journal of controlled release : official journal of the Controlled Release Society, 2008 Jul 17 - Who cited this? | PubMed ID: 18700157 | Fulltext

Six novel mutations of the ADAR1 gene in patients with dyschromatosis symmetrica hereditaria: Histological observation and comparison of genotypes and clinical phenotypes.

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Kondo T, Suzuki T, Mitsuhashi Y, Ito S, Kono M, Komine M, Akita H, and Tomita Y

The Journal of dermatology 35(7):395-406, 2008 Jul - Who cited this? | PubMed ID: 18705826 | Fulltext

Photosensitized Breakage and Damage of DNA by CdSe-ZnS Quantum Dots.

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Anas A, Akita H, Harashima H, Itoh T, Ishikawa M, and Biju V

The journal of physical chemistry. B, 2008 Jun 26 - Who cited this? | PubMed ID: 18582008 | Fulltext

Image of the month. Gastrocolic fistula associated with a gastric ulcer.

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Iida T, Akita H, Sasaki M, Hanyu N, and Yanaga K

Archives of surgery (Chicago, Ill. : 1960) 143(6):609-10, 2008 Jun - Who cited this? | PubMed ID: 18559759 | Fulltext

[Childhood bacterial meningitis trends in Japan from 2005 to 2006].

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Sunakawa K, Ubukata K, Chiba N, Hasegawa K, Nonoyama M, Iwata S, Akita H, and Sato Y

Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 82(3):187, 2008 May - Who cited this? | PubMed ID: 18546848 | Fulltext

[Non-small-cell lung cancer].

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Akita H and Kinoshita I

Gan to kagaku ryoho. Cancer & chemotherapy 35(5):720, 2008 May - Who cited this? | PubMed ID: 18487906 | Fulltext

Heterologous expression of Na+/H+ antiporter gene (CvNHA1) from salt-tolerant yeast Candida versatilis in Saccharomyces cerevisiae Na+-transporter deficient mutants.

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Watanabe Y, Akita H, Higuchi Y, Tsujimatsu R, Kaneta T, and Tamai Y

Bioscience, biotechnology, and biochemistry 72(4):1005-14, 2008 Apr - Who cited this? | PubMed ID: 18391463 | Fulltext

Multifunctional envelope-type nano device (MEND) as a non-viral gene delivery system.

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Kogure K, Akita H, Yamada Y, and Harashima H

Advanced drug delivery reviews 60(4-5):559, 2008 Mar 1 - Who cited this? | PubMed ID: 18037529 | Fulltext

Autopsy cases of fulminant-type bacterial infection with necrotizing fasciitis: Group A (beta) hemolytic Streptococcus pyogenes versus Vibrio vulnificus infection.

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Tajiri T, Tate G, Akita H, Ohike N, Masunaga A, Kunimura T, Mitsuya T, and Morohoshi T

Pathology international 58(3):196-202, 2008 Mar - Who cited this? | PubMed ID: 18251785 | Fulltext

Hepatocyte growth factor improves synaptic localization of the NMDA receptor and intracellular signaling after excitotoxic injury in cultured hippocampal neurons.

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Akita H, Takagi N, Ishihara N, Takagi K, Murotomi K, Funakoshi H, Matsumoto K, Nakamura T, and Takeo S

Experimental neurology 210(1):83-94, 2008 Mar - Who cited this? | PubMed ID: 18001712 | Fulltext

Evaluation of operative complications related to laparoscopic radical prostatectomy.

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Tozawa K, Hashimoto Y, Yasui T, Itoh Y, Nagata D, Akita H, Kawai N, Hayashi Y, and Kohri K

International journal of urology : official journal of the Japanese Urological Association 15(3):222-5, 2008 Mar - Who cited this? | PubMed ID: 18304216 | Fulltext

Concise syntheses of coronarin a, coronarin e, austrochaparol and pacovatinin a.

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Miyake T, Uda K, Kinoshita M, Fujii M, and Akita H

Chemical & pharmaceutical bulletin 56(3):398-403, 2008 Mar - Who cited this? | PubMed ID: 18310958 | Fulltext

[Development of various multifunctional envelope-type nano device MEND based on novel assembly technologies].

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Kogure K, Akita H, and Harashima H

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 128(2):219, 2008 Feb - Who cited this? | PubMed ID: 18239369 | Fulltext

MITO-Porter: A liposome-based carrier system for delivery of macromolecules into mitochondria via membrane fusion.

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Yamada Y, Akita H, Kamiya H, Kogure K, Yamamoto T, Shinohara Y, Yamashita K, Kobayashi H, Kikuchi H, and Harashima H

Biochimica et biophysica acta 1778(2):423, 2008 Feb - Who cited this? | PubMed ID: 18054323 | Fulltext

Development of lipid particles targeted via sugar-lipid conjugates as novel nuclear gene delivery system.

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Masuda T, Akita H, Nishio T, Niikura K, Kogure K, Ijiro K, and Harashima H

Biomaterials 29(6):709, 2008 Feb - Who cited this? | PubMed ID: 18001828 | Fulltext

Process Development and Large-Scale Synthesis of NK(1) Antagonist.

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Araya I, Kanazawa S, and Akita H

Chemical & pharmaceutical bulletin 56(2):176-80, 2008 Feb - Who cited this? | PubMed ID: 18239303 | Fulltext

A novel IRQ ligand-modified nano-carrier targeted to a unique pathway of caveolar endocytic pathway.

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Mudhakir D, Akita H, Tan E, and Harashima H

Journal of controlled release : official journal of the Controlled Release Society 125(2):164, 2008 Jan 22 - Who cited this? | PubMed ID: 18054812 | Fulltext

Nonviral gene delivery.

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Akita H and Harashima H

Contributions to nephrology 159:13, 2008 - Who cited this? | PubMed ID: 18391582 | Fulltext

Use of a metallic-wall stent in the magnet compression anastomosis technique for bile duct obstruction after liver transplantation.

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Akita H, Hikita H, Yamanouchi E, Marubashi S, Nagano H, Umeshita K, Dono K, Tsutsui S, Hayashi N, and Monden M

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 14(1):118-20, 2008 Jan - Who cited this? | PubMed ID: 18161766 | Fulltext

Chemoenzymatic Synthesis of (+)-alpha-Polypodatetraene and Methyl (5R,10R,13R)-Labda-8-en-15-oate.

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Kinoshita M, Miyake T, Arima Y, Oguma M, and Akita H

Chemical & pharmaceutical bulletin 56(1):118-23, 2008 Jan - Who cited this? | PubMed ID: 18175991 | Fulltext

(R)-ACX, a pancreatic beta-cell selective sulfonylurea, does not aggravate myocardial ischemia-reperfusion damage.

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Namekata I, Yamaguchi Y, Moriguchi S, Yamazaki S, Terasawa A, Yamagishi R, Aikawa T, Saito T, Kurashima K, Seri K, Imamura Y, Akita H, Shigenobu K, and Tanaka H

European journal of pharmacology 577(1-3):211-8, 2007 Dec 22 - Who cited this? | PubMed ID: 17927975 | Fulltext

Lactobacillus hayakitensis sp. nov., isolated from intestines of healthy thoroughbreds.

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Morita H, Shiratori C, Murakami M, Takami H, Kato Y, Endo A, Nakajima F, Takagi M, Akita H, Okada S, and Masaoka T

International journal of systematic and evolutionary microbiology 57(Pt 12):2836-9, 2007 Dec - Who cited this? | PubMed ID: 18048734 | Fulltext

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